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The map label for this gene is gst [C]

Identifier: 182677064

GI number: 182677064

Start: 64407

End: 65102

Strand: Direct

Name: gst [C]

Synonym: Bind_0062

Alternate gene names: 182677064

Gene position: 64407-65102 (Clockwise)

Preceding gene: 182677060

Following gene: 182677065

Centisome position: 1.54

GC content: 57.18

Gene sequence:

>696_bases
ATGAGTTCCGACATCACCCCATTCGATGTAATCAAGCTGCCTAGGATGAAGATTTACGATTTTCCCACGGGCCCTTATCC
GGCGCGTGTGCGTATCGCTTTGGCCGAGAAAAACCTGCAATCGCGCGTCCGGTTTGAGATGGTCGATCTTTACAAAGGTG
AGCACAAGAAGCCCGCGTTCATCGCCACCAAGAATTACTCCGGCACGCTGCCGGTGCTCGAACTCGATGATGGGACCCTG
ATTGCCGAGTGCACGGCCATTACCGAATATCTCGACGCCCTCGATGGCGCTCCGACTCTCACTGGCAGGACACCGCGCGA
AAAAGGCCTGATCCATATGATGAGCAAGCGCGCCGAGTTGGAGTTGCTCGACGCCATCAGTGTTTATTTCCACCACGCCA
CACCAGGGCTTGGACCTGACGTCGAGATTTATCAGAACGCCGAGTGGGGGCTTCGTCAGCGCGACAAAGCCGTGAGGGGG
ATGCACTATTTCGATGGCGTTCTGAGAACACAGCCATTCGTGGCCGGTGAGATCTTCTCGATGGCCGACATCACGGTCAT
CGGCGGTTTGATCTTTGCGGAGATTGTGAAGCTGCCGGTGCCTGCGGAGTGCGAGGCGCTTCAAGCTTGGTACGCAAGGA
TGCAGGAGCGCCCCAGCGTCAAGAACCGGGTGACGATGTCAGAACCGGCCACGTAG

Upstream 100 bases:

>100_bases
GCCTCGCCATCGATTGCCTACCAAGTGACAGATAGACGTTGACCGCCTCAATTTAAAGCCCTATGTGTGATATCTACCAA
TTGGCAGGTAGAGGTGCGCT

Downstream 100 bases:

>100_bases
CGTGAACAATCGATCGGCTTGATCGGGCGCGACGGCGACAGGCCGCCGCCGCGCTGAATATCCGCTTCCAGGATGATCCG
ATGCGGGCACCAGCATCCGA

Product: glutathione S-transferase domain-containing protein

Products: HX; R-S-Glutathione; S-(2,4-dinitrophenyl)glutathione [C]

Alternate protein names: Glutathione S-Transferase; Glutathione S-Transferase Domain Protein; Glutathione S-Transferase Family Protein; Glutathione S-Transferase-Like; Glutathione S-Transferase C-Terminal Domain; Glutathione S-Transferase N-Terminal Domain Protein; Glutathione Transferase; Glutathione S-Transferase Domain; Glutathione-S-Transferase; Glutathione S-Transferase N-Terminal Domain; Glutathione-S Transferase; Glutathione S-Transferase II

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MSSDITPFDVIKLPRMKIYDFPTGPYPARVRIALAEKNLQSRVRFEMVDLYKGEHKKPAFIATKNYSGTLPVLELDDGTL
IAECTAITEYLDALDGAPTLTGRTPREKGLIHMMSKRAELELLDAISVYFHHATPGLGPDVEIYQNAEWGLRQRDKAVRG
MHYFDGVLRTQPFVAGEIFSMADITVIGGLIFAEIVKLPVPAECEALQAWYARMQERPSVKNRVTMSEPAT

Sequences:

>Translated_231_residues
MSSDITPFDVIKLPRMKIYDFPTGPYPARVRIALAEKNLQSRVRFEMVDLYKGEHKKPAFIATKNYSGTLPVLELDDGTL
IAECTAITEYLDALDGAPTLTGRTPREKGLIHMMSKRAELELLDAISVYFHHATPGLGPDVEIYQNAEWGLRQRDKAVRG
MHYFDGVLRTQPFVAGEIFSMADITVIGGLIFAEIVKLPVPAECEALQAWYARMQERPSVKNRVTMSEPAT
>Mature_230_residues
SSDITPFDVIKLPRMKIYDFPTGPYPARVRIALAEKNLQSRVRFEMVDLYKGEHKKPAFIATKNYSGTLPVLELDDGTLI
AECTAITEYLDALDGAPTLTGRTPREKGLIHMMSKRAELELLDAISVYFHHATPGLGPDVEIYQNAEWGLRQRDKAVRGM
HYFDGVLRTQPFVAGEIFSMADITVIGGLIFAEIVKLPVPAECEALQAWYARMQERPSVKNRVTMSEPAT

Specific function: Conjugation Of Reduced Glutathione To A Wide Number Of Exogenous And Endogenous Hydrophobic Electrophiles. [C]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Saccharomyces cerevisiae, GI6322968, Length=208, Percent_Identity=78.8461538461538, Blast_Score=348, Evalue=5e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.5.1.18 [C]

Molecular weight: Translated: 25888; Mature: 25757

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDITPFDVIKLPRMKIYDFPTGPYPARVRIALAEKNLQSRVRFEMVDLYKGEHKKPAF
CCCCCCCHHHEECCCEEEEECCCCCCCCEEEEEEEHHCHHHHHHHHHHHHHCCCCCCCEE
IATKNYSGTLPVLELDDGTLIAECTAITEYLDALDGAPTLTGRTPREKGLIHMMSKRAEL
EEECCCCCCCCEEEECCCCEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
ELLDAISVYFHHATPGLGPDVEIYQNAEWGLRQRDKAVRGMHYFDGVLRTQPFVAGEIFS
HHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
MADITVIGGLIFAEIVKLPVPAECEALQAWYARMQERPSVKNRVTMSEPAT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHCEECCCCCC
>Mature Secondary Structure 
SSDITPFDVIKLPRMKIYDFPTGPYPARVRIALAEKNLQSRVRFEMVDLYKGEHKKPAF
CCCCCCHHHEECCCEEEEECCCCCCCCEEEEEEEHHCHHHHHHHHHHHHHCCCCCCCEE
IATKNYSGTLPVLELDDGTLIAECTAITEYLDALDGAPTLTGRTPREKGLIHMMSKRAEL
EEECCCCCCCCEEEECCCCEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
ELLDAISVYFHHATPGLGPDVEIYQNAEWGLRQRDKAVRGMHYFDGVLRTQPFVAGEIFS
HHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
MADITVIGGLIFAEIVKLPVPAECEALQAWYARMQERPSVKNRVTMSEPAT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; Glutathione; 1-chloro-2,4-dinitrobenzene; reduced glutathione [C]

Specific reaction: RX + Glutathione = HX + R-S-Glutathione 1-chloro-2,4-dinitrobenzene + reduced glutathione = S-(2,4-dinitrophenyl)glutathione [C]

General reaction: Aryl group transfer [C]

Inhibitor: Cd2+; CibacronBlue; Co2+; Cu2+; Hematin; Hg2+; Ni2+; Sulfophthaleins; Tributyl tinacetate; Triethyl tinbromide; Zn2+ [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA