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The map label for this gene is atpA [H]

Identifier: 17548036

GI number: 17548036

Start: 3582345

End: 3583886

Strand: Reverse

Name: atpA [H]

Synonym: RSc3319

Alternate gene names: 17548036

Gene position: 3583886-3582345 (Counterclockwise)

Preceding gene: 17548037

Following gene: 17548035

Centisome position: 96.43

GC content: 63.49

Gene sequence:

>1542_bases
ATGCAACTGAACCCCTCCGAGATCAGCGACCTGATCAAGACCCGTATCGAGGGCTTGAAGGCTGGCGCTGACGCAAAGAA
CACCGGCACGGTCATCTCCGTGACGGACGGCATCTGCCGCATTCACGGCCTGTCGGGCGTGATGCAGGGCGAAATGCTGG
AATTCCCGGGCAACACGTTCGGCCTCGCGCTGAACCTCGAGCGCGACTCCGTCGGCGCCGTGGTGCTGGGTGACTACGAG
CACATTTCCGAAGGCAACGAAGTCAAGTGCACGGGCCGCATCCTGGAAGTGCCGGTCGGCCCTGAACTGCTTGGCCGCGT
GGTCAACGCGCTGGGCCAGCCGATCGACGGCAAGGGCCCGATCAACGCCAAGAAAACGGACGTGATCGAGAAGGTTGCCC
CGGGCGTGATCGCACGTCAGTCGGTGAGCCAGCCGGTGCAAACCGGCCTGAAGTCGATCGACGCGATGGTGCCGATCGGC
CGTGGCCAGCGTGAGCTGATCATTGGCGACCGCCAGACCGGCAAGACCGCCGTCGCAGTCGACGCCATCATCAACCAGAA
GGGCAAGGGCATCTTCTGCGTGTACGTGGCAATCGGCCAGAAGGCCTCGACGATCGCCAACGTGGTGCGCAAGCTGGAAG
AGCACGGCGCGCTGGAATACACGATCGTGGTGGCTGCCGCCGCTTCCGACTCGGCTGCCATGCAGTACCTGTCGGCCTAC
GCCGGCTGCACGATGGGCGAATACTTCCGCGACCGCGGTGAAGACGCCCTGATCGTTTATGACGACCTGACCAAGCAAGC
TTGGGCTTACCGTCAAGTCTCGCTGCTGCTGCGCCGTCCGCCGGGCCGTGAAGCCTACCCGGGCGACGTGTTCTACCTGC
ACTCGCGCCTGCTGGAGCGTGCTGCCCGTGTGAACGCCGAGCACATCGAGAAGATCACCAACGGTGAAGTCAAGGGCAAG
ACCGGTTCGCTGACCGCACTGCCCGTGATCGAAACGCAGGCCGGCGACGTGTCCGCGTTCGTGCCGACCAACGTGATCTC
GATTACCGACGGCCAGATCTTCCTGGAAACCGACCTGTTCAACGCCGGTATCCGCCCCGCCATCAACGCCGGTATCTCGG
TGTCGCGTGTGGGTGGCGCTGCGCAGACCAAGGTCGTCAAGAAGCTGTCCGGCGGTATCCGTACCGACCTGGCCCAGTAC
CGTGAGCTGGCTGCGTTCGCGCAGTTCGCTTCCGACCTGGACGAGGCGACCCGCAAGCAGCTCGAGCGCGGCCGCCGCGT
GACCGAACTGCTCAAGCAGCCGCAATACCAGCCGCTGCAAGTGTGGCAGCTGGCCGCGTCGCTGTACGCAGCCAACAATG
GCTTCCTCGACAACGTGGACGTGAAGGACATCCTGGCTTTCGAAAAGGGCCTGCACGACCAGCTGAAGACGAAGTACGCC
GACCTCATCAACCGTATCGAAGACACGAAGGATCTGTCGAAGGACGATGAGGCCGCCCTGCGTGCCGCGATCGAGGATTT
CAAGAAGTCCGCCGCGTTCTAA

Upstream 100 bases:

>100_bases
GATGCAGTCTGCGCTCACCGCCGCGTAATGCTGTTCCGCGAGGCTCGGACGAAATCGACGATATCGCCCCGCGGACAGAT
TGAAGAATTAGGAGCATTCG

Downstream 100 bases:

>100_bases
CCGCGTCATTCCCGGAACTGGTCACGCTTAGCCTGCGTGGCCAGGTCTGAACGGAGAGATAGAAATGGCCGGAACGAAAG
AAATCCGAACCAAGATCAAG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLNPSEISDLIKTRIEGLKAGADAKNTGTVISVTDGICRIHGLSGVMQGEMLEFPGNTFGLALNLERDSVGAVVLGDYE
HISEGNEVKCTGRILEVPVGPELLGRVVNALGQPIDGKGPINAKKTDVIEKVAPGVIARQSVSQPVQTGLKSIDAMVPIG
RGQRELIIGDRQTGKTAVAVDAIINQKGKGIFCVYVAIGQKASTIANVVRKLEEHGALEYTIVVAAAASDSAAMQYLSAY
AGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNAEHIEKITNGEVKGK
TGSLTALPVIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINAGISVSRVGGAAQTKVVKKLSGGIRTDLAQY
RELAAFAQFASDLDEATRKQLERGRRVTELLKQPQYQPLQVWQLAASLYAANNGFLDNVDVKDILAFEKGLHDQLKTKYA
DLINRIEDTKDLSKDDEAALRAAIEDFKKSAAF

Sequences:

>Translated_513_residues
MQLNPSEISDLIKTRIEGLKAGADAKNTGTVISVTDGICRIHGLSGVMQGEMLEFPGNTFGLALNLERDSVGAVVLGDYE
HISEGNEVKCTGRILEVPVGPELLGRVVNALGQPIDGKGPINAKKTDVIEKVAPGVIARQSVSQPVQTGLKSIDAMVPIG
RGQRELIIGDRQTGKTAVAVDAIINQKGKGIFCVYVAIGQKASTIANVVRKLEEHGALEYTIVVAAAASDSAAMQYLSAY
AGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNAEHIEKITNGEVKGK
TGSLTALPVIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINAGISVSRVGGAAQTKVVKKLSGGIRTDLAQY
RELAAFAQFASDLDEATRKQLERGRRVTELLKQPQYQPLQVWQLAASLYAANNGFLDNVDVKDILAFEKGLHDQLKTKYA
DLINRIEDTKDLSKDDEAALRAAIEDFKKSAAF
>Mature_513_residues
MQLNPSEISDLIKTRIEGLKAGADAKNTGTVISVTDGICRIHGLSGVMQGEMLEFPGNTFGLALNLERDSVGAVVLGDYE
HISEGNEVKCTGRILEVPVGPELLGRVVNALGQPIDGKGPINAKKTDVIEKVAPGVIARQSVSQPVQTGLKSIDAMVPIG
RGQRELIIGDRQTGKTAVAVDAIINQKGKGIFCVYVAIGQKASTIANVVRKLEEHGALEYTIVVAAAASDSAAMQYLSAY
AGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLERAARVNAEHIEKITNGEVKGK
TGSLTALPVIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAINAGISVSRVGGAAQTKVVKKLSGGIRTDLAQY
RELAAFAQFASDLDEATRKQLERGRRVTELLKQPQYQPLQVWQLAASLYAANNGFLDNVDVKDILAFEKGLHDQLKTKYA
DLINRIEDTKDLSKDDEAALRAAIEDFKKSAAF

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=510, Percent_Identity=56.4705882352941, Blast_Score=576, Evalue=1e-164,
Organism=Homo sapiens, GI4757810, Length=510, Percent_Identity=56.4705882352941, Blast_Score=576, Evalue=1e-164,
Organism=Homo sapiens, GI32189394, Length=506, Percent_Identity=25.8893280632411, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI19913428, Length=308, Percent_Identity=27.9220779220779, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI19913426, Length=314, Percent_Identity=27.3885350318471, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI19913424, Length=333, Percent_Identity=26.1261261261261, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=69.5906432748538, Blast_Score=737, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=439, Percent_Identity=25.0569476082005, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1788251, Length=281, Percent_Identity=27.7580071174377, Blast_Score=109, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71988063, Length=510, Percent_Identity=56.2745098039216, Blast_Score=574, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI71988080, Length=510, Percent_Identity=56.2745098039216, Blast_Score=573, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI71988074, Length=510, Percent_Identity=52.3529411764706, Blast_Score=525, Evalue=1e-149,
Organism=Caenorhabditis elegans, GI25144756, Length=446, Percent_Identity=24.6636771300448, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17570191, Length=303, Percent_Identity=28.0528052805281, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17510931, Length=382, Percent_Identity=25.3926701570681, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17565854, Length=254, Percent_Identity=26.7716535433071, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=54, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71988068, Length=73, Percent_Identity=42.4657534246575, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=511, Percent_Identity=55.9686888454012, Blast_Score=573, Evalue=1e-164,
Organism=Saccharomyces cerevisiae, GI6322581, Length=427, Percent_Identity=26.463700234192, Blast_Score=126, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6319603, Length=308, Percent_Identity=29.2207792207792, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24658560, Length=510, Percent_Identity=56.8627450980392, Blast_Score=575, Evalue=1e-164,
Organism=Drosophila melanogaster, GI24638766, Length=459, Percent_Identity=25.2723311546841, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281361666, Length=305, Percent_Identity=27.8688524590164, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24646341, Length=305, Percent_Identity=27.8688524590164, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI17136796, Length=305, Percent_Identity=27.8688524590164, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI28574560, Length=385, Percent_Identity=24.4155844155844, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24583992, Length=326, Percent_Identity=25.4601226993865, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24583988, Length=255, Percent_Identity=27.0588235294118, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24583986, Length=255, Percent_Identity=27.0588235294118, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24583984, Length=255, Percent_Identity=27.0588235294118, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI20129479, Length=348, Percent_Identity=25.5747126436782, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55364; Mature: 55364

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNPSEISDLIKTRIEGLKAGADAKNTGTVISVTDGICRIHGLSGVMQGEMLEFPGNTF
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHCCCHHHCCCEEECCCCEE
GLALNLERDSVGAVVLGDYEHISEGNEVKCTGRILEVPVGPELLGRVVNALGQPIDGKGP
EEEEEECCCCCCEEEECCHHHHCCCCEEEEECEEEECCCCHHHHHHHHHHHCCCCCCCCC
INAKKTDVIEKVAPGVIARQSVSQPVQTGLKSIDAMVPIGRGQRELIIGDRQTGKTAVAV
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DAIINQKGKGIFCVYVAIGQKASTIANVVRKLEEHGALEYTIVVAAAASDSAAMQYLSAY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHH
AGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLER
HCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNAEHIEKITNGEVKGKTGSLTALPVIETQAGDVSAFVPTNVISITDGQIFLETDLF
HHHCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECHH
NAGIRPAINAGISVSRVGGAAQTKVVKKLSGGIRTDLAQYRELAAFAQFASDLDEATRKQ
CCCCCHHHHCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGRRVTELLKQPQYQPLQVWQLAASLYAANNGFLDNVDVKDILAFEKGLHDQLKTKYA
HHHCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DLINRIEDTKDLSKDDEAALRAAIEDFKKSAAF
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQLNPSEISDLIKTRIEGLKAGADAKNTGTVISVTDGICRIHGLSGVMQGEMLEFPGNTF
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHCCCHHHCCCEEECCCCEE
GLALNLERDSVGAVVLGDYEHISEGNEVKCTGRILEVPVGPELLGRVVNALGQPIDGKGP
EEEEEECCCCCCEEEECCHHHHCCCCEEEEECEEEECCCCHHHHHHHHHHHCCCCCCCCC
INAKKTDVIEKVAPGVIARQSVSQPVQTGLKSIDAMVPIGRGQRELIIGDRQTGKTAVAV
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DAIINQKGKGIFCVYVAIGQKASTIANVVRKLEEHGALEYTIVVAAAASDSAAMQYLSAY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHH
AGCTMGEYFRDRGEDALIVYDDLTKQAWAYRQVSLLLRRPPGREAYPGDVFYLHSRLLER
HCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVNAEHIEKITNGEVKGKTGSLTALPVIETQAGDVSAFVPTNVISITDGQIFLETDLF
HHHCCHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECHH
NAGIRPAINAGISVSRVGGAAQTKVVKKLSGGIRTDLAQYRELAAFAQFASDLDEATRKQ
CCCCCHHHHCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGRRVTELLKQPQYQPLQVWQLAASLYAANNGFLDNVDVKDILAFEKGLHDQLKTKYA
HHHCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DLINRIEDTKDLSKDDEAALRAAIEDFKKSAAF
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA