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The map label for this gene is corA [H]

Identifier: 17547493

GI number: 17547493

Start: 2984681

End: 2985643

Strand: Direct

Name: corA [H]

Synonym: RSc2774

Alternate gene names: 17547493

Gene position: 2984681-2985643 (Clockwise)

Preceding gene: 17547489

Following gene: 17547502

Centisome position: 80.31

GC content: 63.55

Gene sequence:

>963_bases
ATGATCAACCTGTTCGTTGTGCAAAAAGGCCGTCTCGCGCAAGAACAGGTCGAGGACCGCAACGAACTGCTGCAGCACAA
GCCGATCTGGATCGACGTGATCGATCCGGACGACGAAGAGCTGGCCTGGATCAAGGACACCTACGGCGTGGTGCTGCCCG
AGCTGGAACAGCTGGGCGACCTGGAGGCCTCCGCCCGCTACTTCGAGGGCGAAGACAGCCACATCCACATCCGCACCGAC
TTCCTGCTCGACGAGGAGACCAGCTCGCGCAACGTGCGCGTGGCCTTCGTGCTGACCAAGGACGTGCTCTTCTCGATCCA
CGACGAAGACCTGCCGGCGTTCCGGCTGGTGCGCATGCGGGCGCGGCTGCGGCCCGGCTCGGTGCGCAACGCCAAGGACG
TGCTGATGGACCTGTACGCCACCGACGCGGAATACTCGGCCGACTCGATCGAAGAAGTCTACGAACGCCTGGAAGACGCC
AGCAAGCGTGTGCTGGCCGACGAAGTGACCGACCAGGCCGCCGCCGACGTGCTCGAGATCATCGCCCGCGTGGAAGACCT
CAACGGCCGCATCCGCCGCAACGTGATGGACACGCGCCGCGCGGTGTCCTTCCTGCTGCGCAGCCAGATGCTGTCGCCCG
ACCAGCAGGACGAGGCGCGCCAGGTGCTGCGCGACATCGACTCCATCGAGAACCACACCGCCTTCCTGTCCGACAAGGTC
AACTTCCTGATGGACGCCACGGTCGGCTTCATCAACATCAACCAGAACAAGATCATCAAGCTGTTCTCGGTGGTCTCGGT
GGCGCTGATGCCGCCGACCCTGATCGCCTCGATCTACGGCATGAACTTCAAGGTGATGCCGGAGCTGGACTGGGCGGAGG
GCTACCCCTATGCGATCGTGCTGATGATCGTGTCGGCGGCGATCCCGCTGGTGTATTTCCGGCGCAAGGGCTGGCTGAAA
TAG

Upstream 100 bases:

>100_bases
ATCCGCCGTTTCCGGCTGAATCCGCTGCGTCTTTACGCTACACTCGGCGCGTTTTTGGCGCACCCAGCCGCCTGATCGCC
CCAGTTCCAAGGACATCCGC

Downstream 100 bases:

>100_bases
GCCGCACCCGGCGGCGCGGCCCGCTCCAGCGGCAGCATCAGCCCGAGTAGGCCTTGTAGCTCACCTTGTTGGTGCCTGTG
ACTTGGCTCTTGTCGGGAGC

Product: magnesium/cobalt transporter CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MINLFVVQKGRLAQEQVEDRNELLQHKPIWIDVIDPDDEELAWIKDTYGVVLPELEQLGDLEASARYFEGEDSHIHIRTD
FLLDEETSSRNVRVAFVLTKDVLFSIHDEDLPAFRLVRMRARLRPGSVRNAKDVLMDLYATDAEYSADSIEEVYERLEDA
SKRVLADEVTDQAAADVLEIIARVEDLNGRIRRNVMDTRRAVSFLLRSQMLSPDQQDEARQVLRDIDSIENHTAFLSDKV
NFLMDATVGFININQNKIIKLFSVVSVALMPPTLIASIYGMNFKVMPELDWAEGYPYAIVLMIVSAAIPLVYFRRKGWLK

Sequences:

>Translated_320_residues
MINLFVVQKGRLAQEQVEDRNELLQHKPIWIDVIDPDDEELAWIKDTYGVVLPELEQLGDLEASARYFEGEDSHIHIRTD
FLLDEETSSRNVRVAFVLTKDVLFSIHDEDLPAFRLVRMRARLRPGSVRNAKDVLMDLYATDAEYSADSIEEVYERLEDA
SKRVLADEVTDQAAADVLEIIARVEDLNGRIRRNVMDTRRAVSFLLRSQMLSPDQQDEARQVLRDIDSIENHTAFLSDKV
NFLMDATVGFININQNKIIKLFSVVSVALMPPTLIASIYGMNFKVMPELDWAEGYPYAIVLMIVSAAIPLVYFRRKGWLK
>Mature_320_residues
MINLFVVQKGRLAQEQVEDRNELLQHKPIWIDVIDPDDEELAWIKDTYGVVLPELEQLGDLEASARYFEGEDSHIHIRTD
FLLDEETSSRNVRVAFVLTKDVLFSIHDEDLPAFRLVRMRARLRPGSVRNAKDVLMDLYATDAEYSADSIEEVYERLEDA
SKRVLADEVTDQAAADVLEIIARVEDLNGRIRRNVMDTRRAVSFLLRSQMLSPDQQDEARQVLRDIDSIENHTAFLSDKV
NFLMDATVGFININQNKIIKLFSVVSVALMPPTLIASIYGMNFKVMPELDWAEGYPYAIVLMIVSAAIPLVYFRRKGWLK

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=320, Percent_Identity=44.0625, Blast_Score=268, Evalue=5e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36718; Mature: 36718

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLFVVQKGRLAQEQVEDRNELLQHKPIWIDVIDPDDEELAWIKDTYGVVLPELEQLGD
CEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEHHHHCCCCCCCHHHHCC
LEASARYFEGEDSHIHIRTDFLLDEETSSRNVRVAFVLTKDVLFSIHDEDLPAFRLVRMR
CHHHHHHCCCCCCEEEEEEEEEEECCCCCCCEEEEEEEEEHHHHEECCCCCHHHHHHHHH
ARLRPGSVRNAKDVLMDLYATDAEYSADSIEEVYERLEDASKRVLADEVTDQAAADVLEI
HHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IARVEDLNGRIRRNVMDTRRAVSFLLRSQMLSPDQQDEARQVLRDIDSIENHTAFLSDKV
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NFLMDATVGFININQNKIIKLFSVVSVALMPPTLIASIYGMNFKVMPELDWAEGYPYAIV
HHHHHCCEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCCCCCCCCHHHH
LMIVSAAIPLVYFRRKGWLK
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MINLFVVQKGRLAQEQVEDRNELLQHKPIWIDVIDPDDEELAWIKDTYGVVLPELEQLGD
CEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEHHHHCCCCCCCHHHHCC
LEASARYFEGEDSHIHIRTDFLLDEETSSRNVRVAFVLTKDVLFSIHDEDLPAFRLVRMR
CHHHHHHCCCCCCEEEEEEEEEEECCCCCCCEEEEEEEEEHHHHEECCCCCHHHHHHHHH
ARLRPGSVRNAKDVLMDLYATDAEYSADSIEEVYERLEDASKRVLADEVTDQAAADVLEI
HHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IARVEDLNGRIRRNVMDTRRAVSFLLRSQMLSPDQQDEARQVLRDIDSIENHTAFLSDKV
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
NFLMDATVGFININQNKIIKLFSVVSVALMPPTLIASIYGMNFKVMPELDWAEGYPYAIV
HHHHHCCEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCCCCCCCCHHHH
LMIVSAAIPLVYFRRKGWLK
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA