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The map label for this gene is shlB [H]

Identifier: 17546498

GI number: 17546498

Start: 1914456

End: 1916150

Strand: Direct

Name: shlB [H]

Synonym: RSc1779

Alternate gene names: 17546498

Gene position: 1914456-1916150 (Clockwise)

Preceding gene: 17546497

Following gene: 17546502

Centisome position: 51.51

GC content: 65.6

Gene sequence:

>1695_bases
ATGTCGTCTGCTGTTTTACGTGCCGCAGTTCTCTGTGCCGGTACGGCAAGTTCGTTTGCGCTCGCGCAAGTCGCCCCGGC
GCCTGTCAGCGGTCCCGGTCCTGAAGTCCAACGCCTGCAAGAGCAGCAAGCCGACCAAGCCCGCGATCGCGCCAACGCCC
GCCCCGACGTCTTCACGCCGCCTGCGCCAACTCAGGCGATCTCACTGTCTGCGTTGCCCAAGGAAACACCGTGCTTCCCC
ATCCAGGGCATCGTTCTCGAAGACAACGTCTTCAACTGGCTGCCCTACCTGCTCCAGCCCGTCAACGGCCAGTGCGTGGG
CAAGCAGGGGTTGGAAGCCATCGAGCTTCAGGTCAACAACGCGCTCATCGAGCACGGCTATGTCACCTCGCGCGTGCTGA
TTCCGCAGCAGAACCTGGCCGAGGGCGCGCTGCGGCTCAAGGTGTTGCCCGGCCGCATTGGCGCCGTGCGCAATGCGTCG
GATGACAACATAGGCTGGGCACGCATGGCCCTGCTGGCCGGGCCGGGCGATCTGCTGAACCAGCGCGACCTGGACCAGGC
GCTGGAAACCGTCCGCCGTCTGCCGGGCCAGTCGGAGGCGAGTTTCGACATCGTGCCCGGCGCGCAGGTCGGCGAATCGG
ACATCGTGCTCAAGCCAGGCACCGAGAAGCGCTGGCACGCCACGCTGTCGGCGGACAACACCGGCATGAAGAACACCGGC
AAGTACCAGATGAGCGGCTCGCTGGTCATCGATTCGCCGCTGCATCTGTATGACCAGTTGGCGATTTCCGCATCGTCCAA
TACGGACCGTGGCGCGGCCACGCAGGGCACGCGCTCGTACAGCATCAACTGGAGCGTGCCGGTCGGCTATGCGACGGTGT
TCGTGGGGGCCAACCGGTCGCGCTATCGCCAGACCGTGGCCGGGTTCGAAGACCCGATCGTCTACAGCGGCCAGAGCTCC
GAGGTGAACCTGGGGATCAGCGGGGTGCTGCATCGCGATGCCACGTCCCGCACCGGCGCGCAGTTCAAGGTCTTCCGCAA
GATCAACCGCAACTACCTGGACGACACGGAGATCGAGGTGCAGCGCCACGATGTGGTGGGCTACGAGGCATCCATGTCGC
ACCGGCACTATGTCGGGCCGGTGGCGCTCGATGGCGGGATCGCATGGCGTGAAACGCTGCCGGATCACTCCAACGTGCCG
GGCGTGGTGGTGGGCGACACCACCTATGGCGGCCGCTCGCAGATCGAAACCGCGAATGCGAGCCTGTACTGGCCCTTCAA
GGTCGCAAGCCAGGTCTTCGAGTTCAACAGCAACTGGGCCATTCAGCATGCCCGCACGCGCGTGCTGCCGAGCGATTACT
TCACGATCGGCAACCGCTACACCGTGCGCGGCTTCGACGGCCAGTTGACGCTGGCGGCCGAGGATGGCTGGTACTGGCGC
AACGAACTGGCGTGGCGTGTGGCCGGACAGGCCATCTACGGTGGCATCGATGTGGGCAAGGTGCATGGGCCGAGCGCCGA
ATCCTTGCTCGGCGAGCAGTTGGTCGGTGCCGTGATCGGTGTGCGCGGGCGGGTGCCGTCGGGGCGCTATGCGACGGTCA
ACTACGATCTGTCGTTCGGCTGGCCGCTGTCCAAGCCGGCGGGCTTCCGCTCCGAGCGGCCGGCGGTGATGGCGCAGGTG
GGTGTCGAATTTTAG

Upstream 100 bases:

>100_bases
CGCCGAAAATGGAACAGTTCGACTGGCAGGCATGCCATCCGACGCCGCAGCCTATCAACAGTCGGAGCAATTGAGCGCTC
CCGCCTAACGTTTCTTTCCC

Downstream 100 bases:

>100_bases
GGCGGTGGAACGCACTCAAAAGTGCGAAGCGTTATCGGCGACGGAGGGTACCTGTCGCGCAGTTCTTTTCCGGATGCGCA
GGCACACCGGCACCGATTTC

Product: activation/secretion signal peptide protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 564; Mature: 563

Protein sequence:

>564_residues
MSSAVLRAAVLCAGTASSFALAQVAPAPVSGPGPEVQRLQEQQADQARDRANARPDVFTPPAPTQAISLSALPKETPCFP
IQGIVLEDNVFNWLPYLLQPVNGQCVGKQGLEAIELQVNNALIEHGYVTSRVLIPQQNLAEGALRLKVLPGRIGAVRNAS
DDNIGWARMALLAGPGDLLNQRDLDQALETVRRLPGQSEASFDIVPGAQVGESDIVLKPGTEKRWHATLSADNTGMKNTG
KYQMSGSLVIDSPLHLYDQLAISASSNTDRGAATQGTRSYSINWSVPVGYATVFVGANRSRYRQTVAGFEDPIVYSGQSS
EVNLGISGVLHRDATSRTGAQFKVFRKINRNYLDDTEIEVQRHDVVGYEASMSHRHYVGPVALDGGIAWRETLPDHSNVP
GVVVGDTTYGGRSQIETANASLYWPFKVASQVFEFNSNWAIQHARTRVLPSDYFTIGNRYTVRGFDGQLTLAAEDGWYWR
NELAWRVAGQAIYGGIDVGKVHGPSAESLLGEQLVGAVIGVRGRVPSGRYATVNYDLSFGWPLSKPAGFRSERPAVMAQV
GVEF

Sequences:

>Translated_564_residues
MSSAVLRAAVLCAGTASSFALAQVAPAPVSGPGPEVQRLQEQQADQARDRANARPDVFTPPAPTQAISLSALPKETPCFP
IQGIVLEDNVFNWLPYLLQPVNGQCVGKQGLEAIELQVNNALIEHGYVTSRVLIPQQNLAEGALRLKVLPGRIGAVRNAS
DDNIGWARMALLAGPGDLLNQRDLDQALETVRRLPGQSEASFDIVPGAQVGESDIVLKPGTEKRWHATLSADNTGMKNTG
KYQMSGSLVIDSPLHLYDQLAISASSNTDRGAATQGTRSYSINWSVPVGYATVFVGANRSRYRQTVAGFEDPIVYSGQSS
EVNLGISGVLHRDATSRTGAQFKVFRKINRNYLDDTEIEVQRHDVVGYEASMSHRHYVGPVALDGGIAWRETLPDHSNVP
GVVVGDTTYGGRSQIETANASLYWPFKVASQVFEFNSNWAIQHARTRVLPSDYFTIGNRYTVRGFDGQLTLAAEDGWYWR
NELAWRVAGQAIYGGIDVGKVHGPSAESLLGEQLVGAVIGVRGRVPSGRYATVNYDLSFGWPLSKPAGFRSERPAVMAQV
GVEF
>Mature_563_residues
SSAVLRAAVLCAGTASSFALAQVAPAPVSGPGPEVQRLQEQQADQARDRANARPDVFTPPAPTQAISLSALPKETPCFPI
QGIVLEDNVFNWLPYLLQPVNGQCVGKQGLEAIELQVNNALIEHGYVTSRVLIPQQNLAEGALRLKVLPGRIGAVRNASD
DNIGWARMALLAGPGDLLNQRDLDQALETVRRLPGQSEASFDIVPGAQVGESDIVLKPGTEKRWHATLSADNTGMKNTGK
YQMSGSLVIDSPLHLYDQLAISASSNTDRGAATQGTRSYSINWSVPVGYATVFVGANRSRYRQTVAGFEDPIVYSGQSSE
VNLGISGVLHRDATSRTGAQFKVFRKINRNYLDDTEIEVQRHDVVGYEASMSHRHYVGPVALDGGIAWRETLPDHSNVPG
VVVGDTTYGGRSQIETANASLYWPFKVASQVFEFNSNWAIQHARTRVLPSDYFTIGNRYTVRGFDGQLTLAAEDGWYWRN
ELAWRVAGQAIYGGIDVGKVHGPSAESLLGEQLVGAVIGVRGRVPSGRYATVNYDLSFGWPLSKPAGFRSERPAVMAQVG
VEF

Specific function: Member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 61073; Mature: 60942

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAVLRAAVLCAGTASSFALAQVAPAPVSGPGPEVQRLQEQQADQARDRANARPDVFTP
CCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
PAPTQAISLSALPKETPCFPIQGIVLEDNVFNWLPYLLQPVNGQCVGKQGLEAIELQVNN
CCCCCEEEEECCCCCCCCCCEEEEEEECCHHHHHHHHHCCCCCEEECCCCCEEEEEEECC
ALIEHGYVTSRVLIPQQNLAEGALRLKVLPGRIGAVRNASDDNIGWARMALLAGPGDLLN
EEEECCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCHHHCC
QRDLDQALETVRRLPGQSEASFDIVPGAQVGESDIVLKPGTEKRWHATLSADNTGMKNTG
HHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEECCCCCCCEEEEEECCCCCCCCCC
KYQMSGSLVIDSPLHLYDQLAISASSNTDRGAATQGTRSYSINWSVPVGYATVFVGANRS
CEEEECCEEECCCHHHHHHEEEECCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEECCHH
RYRQTVAGFEDPIVYSGQSSEVNLGISGVLHRDATSRTGAQFKVFRKINRNYLDDTEIEV
HHHHHHCCCCCCEEECCCCCEEEECEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCEEEE
QRHDVVGYEASMSHRHYVGPVALDGGIAWRETLPDHSNVPGVVVGDTTYGGRSQIETANA
EECEEECEECCCCCCEEECCEEECCCEEEHHCCCCCCCCCEEEECCCCCCCCCEEEECCC
SLYWPFKVASQVFEFNSNWAIQHARTRVLPSDYFTIGNRYTVRGFDGQLTLAAEDGWYWR
EEEEHHHHHHHHHHCCCCEEEEEHHHCCCCCCCEECCCEEEEEECCCEEEEEECCCCEEC
NELAWRVAGQAIYGGIDVGKVHGPSAESLLGEQLVGAVIGVRGRVPSGRYATVNYDLSFG
CCCEEEEECEEEECCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEC
WPLSKPAGFRSERPAVMAQVGVEF
CCCCCCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure 
SSAVLRAAVLCAGTASSFALAQVAPAPVSGPGPEVQRLQEQQADQARDRANARPDVFTP
CCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
PAPTQAISLSALPKETPCFPIQGIVLEDNVFNWLPYLLQPVNGQCVGKQGLEAIELQVNN
CCCCCEEEEECCCCCCCCCCEEEEEEECCHHHHHHHHHCCCCCEEECCCCCEEEEEEECC
ALIEHGYVTSRVLIPQQNLAEGALRLKVLPGRIGAVRNASDDNIGWARMALLAGPGDLLN
EEEECCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCHHHCC
QRDLDQALETVRRLPGQSEASFDIVPGAQVGESDIVLKPGTEKRWHATLSADNTGMKNTG
HHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEECCCCCCCEEEEEECCCCCCCCCC
KYQMSGSLVIDSPLHLYDQLAISASSNTDRGAATQGTRSYSINWSVPVGYATVFVGANRS
CEEEECCEEECCCHHHHHHEEEECCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEECCHH
RYRQTVAGFEDPIVYSGQSSEVNLGISGVLHRDATSRTGAQFKVFRKINRNYLDDTEIEV
HHHHHHCCCCCCEEECCCCCEEEECEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCEEEE
QRHDVVGYEASMSHRHYVGPVALDGGIAWRETLPDHSNVPGVVVGDTTYGGRSQIETANA
EECEEECEECCCCCCEEECCEEECCCEEEHHCCCCCCCCCEEEECCCCCCCCCEEEECCC
SLYWPFKVASQVFEFNSNWAIQHARTRVLPSDYFTIGNRYTVRGFDGQLTLAAEDGWYWR
EEEEHHHHHHHHHHCCCCEEEEEHHHCCCCCCCEECCCEEEEEECCCEEEEEECCCCEEC
NELAWRVAGQAIYGGIDVGKVHGPSAESLLGEQLVGAVIGVRGRVPSGRYATVNYDLSFG
CCCEEEEECEEEECCEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEC
WPLSKPAGFRSERPAVMAQVGVEF
CCCCCCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3290200 [H]