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The map label for this gene is pqqE [H]

Identifier: 17546447

GI number: 17546447

Start: 1848649

End: 1850124

Strand: Direct

Name: pqqE [H]

Synonym: RSc1728

Alternate gene names: 17546447

Gene position: 1848649-1850124 (Clockwise)

Preceding gene: 17546446

Following gene: 17546449

Centisome position: 49.74

GC content: 68.77

Gene sequence:

>1476_bases
ATGAGCCTGCAGACCCCGCAGCCGGCCCGCTACCTGCATGCGGACGATTTCAAGCGCTACGTTCCCGTTCACGTGGTCTG
GGAAATCACCCTGGCCTGTGACCTCAAATGCCTGCATTGCGGCTCCCGCGCCGGACGACGGCGACCCGACGAGCTCAATA
CCGCGGAGTGCCTGGAAGTCATCGAATCGCTCGCGCGGCTGGGCACGCGGGAGGTCTCGCTGATCGGCGGCGAAGCGTAT
CTGCGCAAGGACTGGACCGAGCTGATCCGGGCGATCCGTTCCCACGACATGTACTGCGCGGTCCAGACCGGGGGGCGCAA
CCTGACGCCCAAGCGGCTGGAGCAGGCGGTCGAGGCCGGGCTCAACGGCGTGGGCGTCTCGCTCGACGGGCTGGCGCCGC
TGCACGACAAGGTGCGCAACGTGCCGGGCTCGTTCGACCGGGCCGTGGATACGCTCAGGCGCGCACGCGCGGCGGGTCTG
GCCATCAGTGTGAACACCCAGATCGGCGCGCAGACCATGCCGGACCTCCCGGCCCTGATGGACACCATCATCGAGCTGGG
CGCGACGCACTGGCAGATCCAGCTGACGGTCGCCATGGGCAATGCGGTCGACAACGATGCGCTGCTGCTCCAGCCGTATC
AGCTGCAGGAGCTGATGCCGCTGCTCGCCAGGCTCTACAAGGAGGGCGTGAGCCGCGGGCTGCTGATGAACGTCGGCAAC
AACATCGGCTACTACGGCCCCTATGAGCATCTGTGGCGCGGCTTCGGCGACGAGCGCGTGCACTGGAACGGCTGCGCGGC
GGGCCAGACGGTGATCGCGCTGGAGGCGGACGGCACCGTGAAGGGCTGCCCCTCACTGGCGACGGTGGGCTTTGCCGGGG
GCAATGTCCGCGACCTGTCGCTGGAAGACATCTGGCGCACCAGCGAGGCCATCCACTTCGGCCGCCTGCGCTCGGTGGAC
GATCTGTGGGGCTTCTGCCGGACCTGCTACTACGCCGATGCCTGCCGGGGCGGCTGCACCTGGACCTCGCATTCGCTGCT
CGGCAAGCCGGGCAACAACCCGTATTGCCACTATCGCGTGCTGGAGCTGCAGAAGCAGGGGCTGCGCGAGCGGATCGTCA
AGGAGCAGGACGCCGCCGGCGCCTCCTTCGCGGTCGGGCGCTTCGACCTGGTCACGGAGCGCATCGCGGACGGCACGCCC
GTGGCCAGCATCGTGCGCTCCGGCCAGATTGTCGAGCTGGCGTGGAAGCACAAGGGCAAGCGCGCGCCGGAGGTCGGGCG
GGTGCCGCCGCAACTGAGCCTCTGCCGCAGCTGCAACAGCTACATCTATCCGCACGAGCAGACGTGTCCGCATTGCGGTG
CGGATGTCGAGGCGGGGGCGCAGGCGCATCGCCAGGAAGCGCAGCGGCGGCGGGCGGTGGTGAACCAGCTCGAGCAACTG
CTGGGACTGCCGGCCTCGACGTTCGGGGACGCCTGA

Upstream 100 bases:

>100_bases
CTGAGTCTCGCGCGAGACCGGCCTGCCGCCGCATGCCCTGGCCGCCGGCCGGGCATGCGGCCCAATTCCCCATAAGAAAA
GAACAAGACAGCGAGGCGAT

Downstream 100 bases:

>100_bases
GGCGCTTGCCCGGGGCGGGCGCATGCCGGCGCGCCTTCGGGGCGCGCTAAGCGTCCGGCGTGATCGGCGCCAGGTGCGGC
GCGAGCTGTTCGGCGACCCA

Product: hypothetical protein

Products: NA

Alternate protein names: Pyrroloquinoline quinone biosynthesis protein E [H]

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MSLQTPQPARYLHADDFKRYVPVHVVWEITLACDLKCLHCGSRAGRRRPDELNTAECLEVIESLARLGTREVSLIGGEAY
LRKDWTELIRAIRSHDMYCAVQTGGRNLTPKRLEQAVEAGLNGVGVSLDGLAPLHDKVRNVPGSFDRAVDTLRRARAAGL
AISVNTQIGAQTMPDLPALMDTIIELGATHWQIQLTVAMGNAVDNDALLLQPYQLQELMPLLARLYKEGVSRGLLMNVGN
NIGYYGPYEHLWRGFGDERVHWNGCAAGQTVIALEADGTVKGCPSLATVGFAGGNVRDLSLEDIWRTSEAIHFGRLRSVD
DLWGFCRTCYYADACRGGCTWTSHSLLGKPGNNPYCHYRVLELQKQGLRERIVKEQDAAGASFAVGRFDLVTERIADGTP
VASIVRSGQIVELAWKHKGKRAPEVGRVPPQLSLCRSCNSYIYPHEQTCPHCGADVEAGAQAHRQEAQRRRAVVNQLEQL
LGLPASTFGDA

Sequences:

>Translated_491_residues
MSLQTPQPARYLHADDFKRYVPVHVVWEITLACDLKCLHCGSRAGRRRPDELNTAECLEVIESLARLGTREVSLIGGEAY
LRKDWTELIRAIRSHDMYCAVQTGGRNLTPKRLEQAVEAGLNGVGVSLDGLAPLHDKVRNVPGSFDRAVDTLRRARAAGL
AISVNTQIGAQTMPDLPALMDTIIELGATHWQIQLTVAMGNAVDNDALLLQPYQLQELMPLLARLYKEGVSRGLLMNVGN
NIGYYGPYEHLWRGFGDERVHWNGCAAGQTVIALEADGTVKGCPSLATVGFAGGNVRDLSLEDIWRTSEAIHFGRLRSVD
DLWGFCRTCYYADACRGGCTWTSHSLLGKPGNNPYCHYRVLELQKQGLRERIVKEQDAAGASFAVGRFDLVTERIADGTP
VASIVRSGQIVELAWKHKGKRAPEVGRVPPQLSLCRSCNSYIYPHEQTCPHCGADVEAGAQAHRQEAQRRRAVVNQLEQL
LGLPASTFGDA
>Mature_490_residues
SLQTPQPARYLHADDFKRYVPVHVVWEITLACDLKCLHCGSRAGRRRPDELNTAECLEVIESLARLGTREVSLIGGEAYL
RKDWTELIRAIRSHDMYCAVQTGGRNLTPKRLEQAVEAGLNGVGVSLDGLAPLHDKVRNVPGSFDRAVDTLRRARAAGLA
ISVNTQIGAQTMPDLPALMDTIIELGATHWQIQLTVAMGNAVDNDALLLQPYQLQELMPLLARLYKEGVSRGLLMNVGNN
IGYYGPYEHLWRGFGDERVHWNGCAAGQTVIALEADGTVKGCPSLATVGFAGGNVRDLSLEDIWRTSEAIHFGRLRSVDD
LWGFCRTCYYADACRGGCTWTSHSLLGKPGNNPYCHYRVLELQKQGLRERIVKEQDAAGASFAVGRFDLVTERIADGTPV
ASIVRSGQIVELAWKHKGKRAPEVGRVPPQLSLCRSCNSYIYPHEQTCPHCGADVEAGAQAHRQEAQRRRAVVNQLEQLL
GLPASTFGDA

Specific function: Together With Moac, Is Involved In The Conversion Of A Guanosine Derivative (Gxp) Into Molybdopterin Precursor Z. [C]

COG id: COG0535

COG function: function code R; Predicted Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. PqqE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR017200
- InterPro:   IPR011843
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 54015; Mature: 53884

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQTPQPARYLHADDFKRYVPVHVVWEITLACDLKCLHCGSRAGRRRPDELNTAECLEV
CCCCCCCCCCCCCHHHHHHCCCEEEEEEEEHHHCCHHHHCCCCCCCCCCCCCCHHHHHHH
IESLARLGTREVSLIGGEAYLRKDWTELIRAIRSHDMYCAVQTGGRNLTPKRLEQAVEAG
HHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCC
LNGVGVSLDGLAPLHDKVRNVPGSFDRAVDTLRRARAAGLAISVNTQIGAQTMPDLPALM
CCCCCEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHH
DTIIELGATHWQIQLTVAMGNAVDNDALLLQPYQLQELMPLLARLYKEGVSRGLLMNVGN
HHHHHHCCCEEEEEEEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCEEEECCC
NIGYYGPYEHLWRGFGDERVHWNGCAAGQTVIALEADGTVKGCPSLATVGFAGGNVRDLS
CCCCCCCHHHHHCCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCHHEEECCCCCEEECC
LEDIWRTSEAIHFGRLRSVDDLWGFCRTCYYADACRGGCTWTSHSLLGKPGNNPYCHYRV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEH
LELQKQGLRERIVKEQDAAGASFAVGRFDLVTERIADGTPVASIVRSGQIVELAWKHKGK
HHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEECCCCC
RAPEVGRVPPQLSLCRSCNSYIYPHEQTCPHCGADVEAGAQAHRQEAQRRRAVVNQLEQL
CCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LGLPASTFGDA
HCCCCHHCCCC
>Mature Secondary Structure 
SLQTPQPARYLHADDFKRYVPVHVVWEITLACDLKCLHCGSRAGRRRPDELNTAECLEV
CCCCCCCCCCCCHHHHHHCCCEEEEEEEEHHHCCHHHHCCCCCCCCCCCCCCHHHHHHH
IESLARLGTREVSLIGGEAYLRKDWTELIRAIRSHDMYCAVQTGGRNLTPKRLEQAVEAG
HHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCC
LNGVGVSLDGLAPLHDKVRNVPGSFDRAVDTLRRARAAGLAISVNTQIGAQTMPDLPALM
CCCCCEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHH
DTIIELGATHWQIQLTVAMGNAVDNDALLLQPYQLQELMPLLARLYKEGVSRGLLMNVGN
HHHHHHCCCEEEEEEEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCEEEECCC
NIGYYGPYEHLWRGFGDERVHWNGCAAGQTVIALEADGTVKGCPSLATVGFAGGNVRDLS
CCCCCCCHHHHHCCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCHHEEECCCCCEEECC
LEDIWRTSEAIHFGRLRSVDDLWGFCRTCYYADACRGGCTWTSHSLLGKPGNNPYCHYRV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEH
LELQKQGLRERIVKEQDAAGASFAVGRFDLVTERIADGTPVASIVRSGQIVELAWKHKGK
HHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEECCCCC
RAPEVGRVPPQLSLCRSCNSYIYPHEQTCPHCGADVEAGAQAHRQEAQRRRAVVNQLEQL
CCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LGLPASTFGDA
HCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA