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The map label for this gene is kup2

Identifier: 17546340

GI number: 17546340

Start: 1739587

End: 1741488

Strand: Direct

Name: kup2

Synonym: RSc1621

Alternate gene names: 17546340

Gene position: 1739587-1741488 (Clockwise)

Preceding gene: 17546338

Following gene: 17546343

Centisome position: 46.81

GC content: 64.72

Gene sequence:

>1902_bases
ATGAGTCAAGCTCTTACAGCAACGGGATCCTCGCAATCCAACGTGAACCTGCGCGCCATGGTGGTCGGCGCCGTGGGCGT
GGTGTTCGGCGACATCGGCACCAGTCCGCTGTACGCGCTCAAGGAGTGCTTCAGTCCCGAGCACGGCATTCCGTTTTCCA
CCGCCGCGGTGCTGGGCATCATCTCCATGCTGTTCTGGGCGATGGTGATCGTGGTGTCGCTCAAGTACGTGCTGTTCGTC
ATGCGCGCCGACAACAACGGCGAAGGCGGCATCCTCGCGCTGATGGCGCTGTCGCTGCGCACCGCGAACAAGCAGTCCAA
GCGGATGGCGCTGCTGACCATGCTGGGCGTGTTCGGCGCCTGCATGTTCTACGGCGATGCCGTCATCACGCCGGCCATCT
CGGTGCTTTCGGCCATGGAGGGCCTGGAGATTGCCGCACCGTCGCTGTCTCCGTTCGTGCTGCCGATCACGGTGGTGATC
CTGGCGGCGCTGTTCCTGATCCAGCGCGGGGGCACGTCGGTGGTGGGCAAGCTGTTCGGGCCCGTGATGCTGGTCTGGTT
CGCCGCGCTGGCCGCGCTGGGCCTGGTCAATCTGATGAAGGCGCCGCAGATCCTGGTGGCCGTCAACCCGGTGTACGCGA
TTGCGTTCCTGCATGAGCATGCGCTGCAGGCGTTCGTCGTGCTGGGCTCGGTGTTCCTGGTGCTGACCGGCGCCGAGGCG
CTGTATGCCGACATGGGGCACTTCGGCGCGCGGCCGATCCGCTGGGGCTGGTTCTTCATCGTGGCGCCGAGCCTGCTGCT
GAACTATTTCGGCCAGGGAGCGATGCTGCTGACTGACCCGAGCACGGTCGAAAACCCGTTCTACCGCGCCGTGCCCGAAG
CGCTGCAGTTGCCGATGGTGGTGCTGGCGGCGGCGGCCACGGTGATCGCATCGCAGGCGGTGATCTCCGGCGCCTTCTCG
CTGACGAGCCAGGCCATCCAGCTGGGCTTTGTGCCGCGCATGCGCATCCGCTATACGTCGGAAGCCGAGATCGGCCAGAT
TTACGTGCCGGTGGTGAACTGGATGCTGCTGATCCTGGTGATCAGCGTGGTGCTGGCGTTCAAGAAGTCCGACAACCTGG
CCGCCGCCTACGGCATCGCCGTGACCACCACGATGGTCATCACGACCGTACTGGCCGCGGTGGTGATGCGCTCGGTCTGG
CGCTGGAATCCGGTGCTGGTGACGCTGGTGAGCCTGGGTTTCCTGGTGGTCGACATGGCGTTCTTCTCGGCCAACCTGCT
GAAGATTCGCGACGGCGGATGGTTCCCGCTGATGCTGGGCGGCGCGGTGTTCTTCCTGCTGATGACGTGGTACAAGGGCC
GCCAGCTGGTGCGCGCACGCAGCCTGGAAGACGGCATTCCGCTCGAACCGTTCCTCGCCGGCCTGCTGGCGCACCCGCCG
CACCGCGTGGAGGGCACGGCTGTGTTCTTGACGGCCAATATCGACTTCGTGCCGGTGTCGCTGTTGCATAACCTGAAGCA
CAACCGCGTGCTGCACGAGCGCGTGATCTTCATCAGCTTCGTCACGCGCGACATCCCCTACGTGGACGACAGGTGCCGCG
TGACCGTGCGCGAATTCGGCAGCGGCATCTACCTCGTCAAGGCGGAATATGGGTTCAAGGAAACGCCGGACGTCTATCGT
GTGCTGGAGCTGGGCCAGCCGCAGATCGGCTCGCGCTGCGAGCTGATGGATACGTCGTTCTTCATCGCGCGGGAATCGGT
GGTGCCGTCCAAGCTGCCGGGCATGTCGATGTGGCGCGAGCGGCTGTTTGCGTGGATGCATCAGAACGGCGCCAAGCCTT
CGGACTTCTTCCATATCCCCGCCAACCGCGTGGTGGAGCTGGGGACCAAGGTCGAGATCTGA

Upstream 100 bases:

>100_bases
GTTCGAGGGGGTTGGCGAGCGAGGGCCCAAGAGTACAATCGCGCCTCATTGTGCATTGCACGATTTTCAAGCGGCCGGCA
GTCGCGGCCGACGACAAGGC

Downstream 100 bases:

>100_bases
CCCGTCGCTTCCGGCAAGAACAAACGGCCCGTGCATCGAATGCACGGGCCGTTTTGCTTGGCGGCGCGGGTGCGCTGCGC
TCAGATCTTCGAGGCGGCCT

Product: potassium uptake transmembrane protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 633; Mature: 632

Protein sequence:

>633_residues
MSQALTATGSSQSNVNLRAMVVGAVGVVFGDIGTSPLYALKECFSPEHGIPFSTAAVLGIISMLFWAMVIVVSLKYVLFV
MRADNNGEGGILALMALSLRTANKQSKRMALLTMLGVFGACMFYGDAVITPAISVLSAMEGLEIAAPSLSPFVLPITVVI
LAALFLIQRGGTSVVGKLFGPVMLVWFAALAALGLVNLMKAPQILVAVNPVYAIAFLHEHALQAFVVLGSVFLVLTGAEA
LYADMGHFGARPIRWGWFFIVAPSLLLNYFGQGAMLLTDPSTVENPFYRAVPEALQLPMVVLAAAATVIASQAVISGAFS
LTSQAIQLGFVPRMRIRYTSEAEIGQIYVPVVNWMLLILVISVVLAFKKSDNLAAAYGIAVTTTMVITTVLAAVVMRSVW
RWNPVLVTLVSLGFLVVDMAFFSANLLKIRDGGWFPLMLGGAVFFLLMTWYKGRQLVRARSLEDGIPLEPFLAGLLAHPP
HRVEGTAVFLTANIDFVPVSLLHNLKHNRVLHERVIFISFVTRDIPYVDDRCRVTVREFGSGIYLVKAEYGFKETPDVYR
VLELGQPQIGSRCELMDTSFFIARESVVPSKLPGMSMWRERLFAWMHQNGAKPSDFFHIPANRVVELGTKVEI

Sequences:

>Translated_633_residues
MSQALTATGSSQSNVNLRAMVVGAVGVVFGDIGTSPLYALKECFSPEHGIPFSTAAVLGIISMLFWAMVIVVSLKYVLFV
MRADNNGEGGILALMALSLRTANKQSKRMALLTMLGVFGACMFYGDAVITPAISVLSAMEGLEIAAPSLSPFVLPITVVI
LAALFLIQRGGTSVVGKLFGPVMLVWFAALAALGLVNLMKAPQILVAVNPVYAIAFLHEHALQAFVVLGSVFLVLTGAEA
LYADMGHFGARPIRWGWFFIVAPSLLLNYFGQGAMLLTDPSTVENPFYRAVPEALQLPMVVLAAAATVIASQAVISGAFS
LTSQAIQLGFVPRMRIRYTSEAEIGQIYVPVVNWMLLILVISVVLAFKKSDNLAAAYGIAVTTTMVITTVLAAVVMRSVW
RWNPVLVTLVSLGFLVVDMAFFSANLLKIRDGGWFPLMLGGAVFFLLMTWYKGRQLVRARSLEDGIPLEPFLAGLLAHPP
HRVEGTAVFLTANIDFVPVSLLHNLKHNRVLHERVIFISFVTRDIPYVDDRCRVTVREFGSGIYLVKAEYGFKETPDVYR
VLELGQPQIGSRCELMDTSFFIARESVVPSKLPGMSMWRERLFAWMHQNGAKPSDFFHIPANRVVELGTKVEI
>Mature_632_residues
SQALTATGSSQSNVNLRAMVVGAVGVVFGDIGTSPLYALKECFSPEHGIPFSTAAVLGIISMLFWAMVIVVSLKYVLFVM
RADNNGEGGILALMALSLRTANKQSKRMALLTMLGVFGACMFYGDAVITPAISVLSAMEGLEIAAPSLSPFVLPITVVIL
AALFLIQRGGTSVVGKLFGPVMLVWFAALAALGLVNLMKAPQILVAVNPVYAIAFLHEHALQAFVVLGSVFLVLTGAEAL
YADMGHFGARPIRWGWFFIVAPSLLLNYFGQGAMLLTDPSTVENPFYRAVPEALQLPMVVLAAAATVIASQAVISGAFSL
TSQAIQLGFVPRMRIRYTSEAEIGQIYVPVVNWMLLILVISVVLAFKKSDNLAAAYGIAVTTTMVITTVLAAVVMRSVWR
WNPVLVTLVSLGFLVVDMAFFSANLLKIRDGGWFPLMLGGAVFFLLMTWYKGRQLVRARSLEDGIPLEPFLAGLLAHPPH
RVEGTAVFLTANIDFVPVSLLHNLKHNRVLHERVIFISFVTRDIPYVDDRCRVTVREFGSGIYLVKAEYGFKETPDVYRV
LELGQPQIGSRCELMDTSFFIARESVVPSKLPGMSMWRERLFAWMHQNGAKPSDFFHIPANRVVELGTKVEI

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=624, Percent_Identity=49.5192307692308, Blast_Score=630, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP2_RALSO (Q8XYY5)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_519742.1
- GeneID:   1220456
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc1621
- NMPDR:   fig|267608.1.peg.1621
- HOGENOM:   HBG351154
- OMA:   KECFSPE
- ProtClustDB:   CLSK897039
- BioCyc:   RSOL267608:RSC1621-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 69027; Mature: 68896

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd4b0f5c)-; HASH(0x47f69304)-; HASH(0xd7007f0)-; HASH(0xd2674a0)-; HASH(0xc712238)-; HASH(0x47fce464)-; HASH(0x47f69a3c)-; HASH(0xd3f1d0c)-; HASH(0xd3c8ec4)-; HASH(0xd754118)-; HASH(0x47f2ab2c)-; HASH(0xce4ad70)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQALTATGSSQSNVNLRAMVVGAVGVVFGDIGTSPLYALKECFSPEHGIPFSTAAVLGI
CCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHH
ISMLFWAMVIVVSLKYVLFVMRADNNGEGGILALMALSLRTANKQSKRMALLTMLGVFGA
HHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
CMFYGDAVITPAISVLSAMEGLEIAAPSLSPFVLPITVVILAALFLIQRGGTSVVGKLFG
HHHHCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
PVMLVWFAALAALGLVNLMKAPQILVAVNPVYAIAFLHEHALQAFVVLGSVFLVLTGAEA
HHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LYADMGHFGARPIRWGWFFIVAPSLLLNYFGQGAMLLTDPSTVENPFYRAVPEALQLPMV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHCCCHHHHHHHHHHHHHH
VLAAAATVIASQAVISGAFSLTSQAIQLGFVPRMRIRYTSEAEIGQIYVPVVNWMLLILV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEHHHHHHHHHHHH
ISVVLAFKKSDNLAAAYGIAVTTTMVITTVLAAVVMRSVWRWNPVLVTLVSLGFLVVDMA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FFSANLLKIRDGGWFPLMLGGAVFFLLMTWYKGRQLVRARSLEDGIPLEPFLAGLLAHPP
HHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
HRVEGTAVFLTANIDFVPVSLLHNLKHNRVLHERVIFISFVTRDIPYVDDRCRVTVREFG
CCCCCEEEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEHHHHC
SGIYLVKAEYGFKETPDVYRVLELGQPQIGSRCELMDTSFFIARESVVPSKLPGMSMWRE
CCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCEEECCHHHEEECCCCCCCCCCHHHHHH
RLFAWMHQNGAKPSDFFHIPANRVVELGTKVEI
HHHHHHHHCCCCCCCEEECCCHHHHHCCCCCCH
>Mature Secondary Structure 
SQALTATGSSQSNVNLRAMVVGAVGVVFGDIGTSPLYALKECFSPEHGIPFSTAAVLGI
CCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHH
ISMLFWAMVIVVSLKYVLFVMRADNNGEGGILALMALSLRTANKQSKRMALLTMLGVFGA
HHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
CMFYGDAVITPAISVLSAMEGLEIAAPSLSPFVLPITVVILAALFLIQRGGTSVVGKLFG
HHHHCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
PVMLVWFAALAALGLVNLMKAPQILVAVNPVYAIAFLHEHALQAFVVLGSVFLVLTGAEA
HHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LYADMGHFGARPIRWGWFFIVAPSLLLNYFGQGAMLLTDPSTVENPFYRAVPEALQLPMV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCHHCCCHHHHHHHHHHHHHH
VLAAAATVIASQAVISGAFSLTSQAIQLGFVPRMRIRYTSEAEIGQIYVPVVNWMLLILV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEHHHHHHHHHHHH
ISVVLAFKKSDNLAAAYGIAVTTTMVITTVLAAVVMRSVWRWNPVLVTLVSLGFLVVDMA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FFSANLLKIRDGGWFPLMLGGAVFFLLMTWYKGRQLVRARSLEDGIPLEPFLAGLLAHPP
HHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
HRVEGTAVFLTANIDFVPVSLLHNLKHNRVLHERVIFISFVTRDIPYVDDRCRVTVREFG
CCCCCEEEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEHHHHC
SGIYLVKAEYGFKETPDVYRVLELGQPQIGSRCELMDTSFFIARESVVPSKLPGMSMWRE
CCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCEEECCHHHEEECCCCCCCCCCHHHHHH
RLFAWMHQNGAKPSDFFHIPANRVVELGTKVEI
HHHHHHHHCCCCCCCEEECCCHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852