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The map label for this gene is 17546325

Identifier: 17546325

GI number: 17546325

Start: 1726314

End: 1727285

Strand: Direct

Name: 17546325

Synonym: RSc1606

Alternate gene names: NA

Gene position: 1726314-1727285 (Clockwise)

Preceding gene: 17546322

Following gene: 17546326

Centisome position: 46.45

GC content: 67.8

Gene sequence:

>972_bases
ATGCTCATGCAGGCCTTCTATACCGATCACTTCGTCCTTCCGCTGCCGCCGGGCCATCGGTTTCCAATGCGCAAATACAG
CCTGCTGCGCGAACGCGCCTTGGCCGAGGTGCCCGGACTCGTCATGCACGAGGCGCCGCGTGCCGGGGACGACGCGCTGC
TGCTGGCCCATGCGCCAGACTACGTCAGTGCCGTGGGCGCCGGCAGGCTGGATCCGGCGAGGCAGCGCGAGATCGGCTTT
CCGTGGTCGCCGGAAATGGTGGAGCGCAGTCGCCGTTCCGCCGGGGCGACCATGGCGGCATGCGAGGCCGCCATGGCCGA
TGGCATCGCGGTCAACCTGGCCGGCGGCACGCATCACGCATACGCGGACAAGGGCGGTGGCTTCTGCGTCTTCAATGACG
CGGCCATCGCCTCGCGCTGGATGCAGCGCCGGCCGGGCCGGACACCGGAGCACTTCCCCGTCGCCATCGTCGACCTGGAC
GTGCATCAGGGCAACGGCACGGCTTCGATTCTGCGCGACGATGCTTCGGTGTTTACGCTGTCGGAGCACGGTGAAAAGAA
TTACCCGTTCCGCAAGGAAGCCTCCGACCTGGATGTCGGTCTGCCGGACGGCTGCGGCGATGCGGCTTATCTGGAGGCGC
TGGCGGGCGCGCTCGACACCCTGGCCGCGCGTTTTGCACCGCGCCTGATCATCTATCTCGCCGGCGCCGATCCGCATGAG
GGCGACCGTCTCGGCCGCCTCAGGCTGACCATGGACGGCCTGGCCCGGCGTGACCGGCAGGTCTTCGATTTCGCCTTCCT
GCGGCGGATTCCGATTGCCGTTACCATGGCGGGCGGCTACGGCAACAACATCGACGACACCGTGGCCGTCCACGCACAGA
CCATTGCGCTGGCGGCCCTGCATGCCGCCCGCTGGGCTGCCGGGGAGGCTGCCACGTCGGTCTCTTCCTCTTCTTTGCCG
CTTTCCGCATGA

Upstream 100 bases:

>100_bases
CGGGGGCTGCTTTCAGGCCGCGCCAGCTACAGAAAAACGTTGCAATAGCCTAGGTTACGATTCTGCCGTCCGCCAATTTT
TCGCTGCAGTGCGATCAAAC

Downstream 100 bases:

>100_bases
CCCAAGCGTATTCGGCCGCACGCATGCCGGCCCTTGATTCCCTGTTCGTGGCTGCCATGCCGTGGTTGTTCGTGCTGATC
TGGAGCACGGGTTTTGTCGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MLMQAFYTDHFVLPLPPGHRFPMRKYSLLRERALAEVPGLVMHEAPRAGDDALLLAHAPDYVSAVGAGRLDPARQREIGF
PWSPEMVERSRRSAGATMAACEAAMADGIAVNLAGGTHHAYADKGGGFCVFNDAAIASRWMQRRPGRTPEHFPVAIVDLD
VHQGNGTASILRDDASVFTLSEHGEKNYPFRKEASDLDVGLPDGCGDAAYLEALAGALDTLAARFAPRLIIYLAGADPHE
GDRLGRLRLTMDGLARRDRQVFDFAFLRRIPIAVTMAGGYGNNIDDTVAVHAQTIALAALHAARWAAGEAATSVSSSSLP
LSA

Sequences:

>Translated_323_residues
MLMQAFYTDHFVLPLPPGHRFPMRKYSLLRERALAEVPGLVMHEAPRAGDDALLLAHAPDYVSAVGAGRLDPARQREIGF
PWSPEMVERSRRSAGATMAACEAAMADGIAVNLAGGTHHAYADKGGGFCVFNDAAIASRWMQRRPGRTPEHFPVAIVDLD
VHQGNGTASILRDDASVFTLSEHGEKNYPFRKEASDLDVGLPDGCGDAAYLEALAGALDTLAARFAPRLIIYLAGADPHE
GDRLGRLRLTMDGLARRDRQVFDFAFLRRIPIAVTMAGGYGNNIDDTVAVHAQTIALAALHAARWAAGEAATSVSSSSLP
LSA
>Mature_323_residues
MLMQAFYTDHFVLPLPPGHRFPMRKYSLLRERALAEVPGLVMHEAPRAGDDALLLAHAPDYVSAVGAGRLDPARQREIGF
PWSPEMVERSRRSAGATMAACEAAMADGIAVNLAGGTHHAYADKGGGFCVFNDAAIASRWMQRRPGRTPEHFPVAIVDLD
VHQGNGTASILRDDASVFTLSEHGEKNYPFRKEASDLDVGLPDGCGDAAYLEALAGALDTLAARFAPRLIIYLAGADPHE
GDRLGRLRLTMDGLARRDRQVFDFAFLRRIPIAVTMAGGYGNNIDDTVAVHAQTIALAALHAARWAAGEAATSVSSSSLP
LSA

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI209862883, Length=257, Percent_Identity=31.9066147859922, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI217272877, Length=263, Percent_Identity=31.9391634980989, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI20070354, Length=296, Percent_Identity=30.0675675675676, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI13128864, Length=297, Percent_Identity=29.6296296296296, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI8923769, Length=208, Percent_Identity=27.4038461538462, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI13128862, Length=291, Percent_Identity=26.1168384879725, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI13128860, Length=307, Percent_Identity=25.7328990228013, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI293336691, Length=159, Percent_Identity=29.559748427673, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI17158039, Length=195, Percent_Identity=29.2307692307692, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI30795202, Length=195, Percent_Identity=29.2307692307692, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI30795204, Length=195, Percent_Identity=29.2307692307692, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI226529806, Length=192, Percent_Identity=31.25, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI153085395, Length=196, Percent_Identity=30.1020408163265, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI169234807, Length=154, Percent_Identity=33.1168831168831, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI148539870, Length=154, Percent_Identity=33.1168831168831, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193207430, Length=274, Percent_Identity=29.9270072992701, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI193206283, Length=180, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17540332, Length=180, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17540334, Length=180, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508561, Length=209, Percent_Identity=30.1435406698565, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17561978, Length=209, Percent_Identity=28.7081339712919, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17537347, Length=261, Percent_Identity=29.8850574712644, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193209491, Length=180, Percent_Identity=28.8888888888889, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25154022, Length=237, Percent_Identity=27.0042194092827, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17534739, Length=186, Percent_Identity=26.8817204301075, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321244, Length=292, Percent_Identity=27.0547945205479, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6323999, Length=291, Percent_Identity=28.5223367697594, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324307, Length=342, Percent_Identity=25.4385964912281, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325325, Length=158, Percent_Identity=31.0126582278481, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24649807, Length=194, Percent_Identity=35.0515463917526, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI281360899, Length=279, Percent_Identity=29.0322580645161, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24642142, Length=279, Percent_Identity=29.0322580645161, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24642146, Length=279, Percent_Identity=29.0322580645161, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24642144, Length=279, Percent_Identity=29.0322580645161, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24657891, Length=308, Percent_Identity=26.2987012987013, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24644244, Length=184, Percent_Identity=27.7173913043478, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 34638; Mature: 34638

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMQAFYTDHFVLPLPPGHRFPMRKYSLLRERALAEVPGLVMHEAPRAGDDALLLAHAPD
CCCEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEECCH
YVSAVGAGRLDPARQREIGFPWSPEMVERSRRSAGATMAACEAAMADGIAVNLAGGTHHA
HHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCEEEEECCCCCEE
YADKGGGFCVFNDAAIASRWMQRRPGRTPEHFPVAIVDLDVHQGNGTASILRDDASVFTL
ECCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCEEEEECCCEEEEE
SEHGEKNYPFRKEASDLDVGLPDGCGDAAYLEALAGALDTLAARFAPRLIIYLAGADPHE
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCC
GDRLGRLRLTMDGLARRDRQVFDFAFLRRIPIAVTMAGGYGNNIDDTVAVHAQTIALAAL
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHH
HAARWAAGEAATSVSSSSLPLSA
HHHHHHCCHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLMQAFYTDHFVLPLPPGHRFPMRKYSLLRERALAEVPGLVMHEAPRAGDDALLLAHAPD
CCCEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEECCH
YVSAVGAGRLDPARQREIGFPWSPEMVERSRRSAGATMAACEAAMADGIAVNLAGGTHHA
HHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCEEEEECCCCCEE
YADKGGGFCVFNDAAIASRWMQRRPGRTPEHFPVAIVDLDVHQGNGTASILRDDASVFTL
ECCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCEEEEECCCEEEEE
SEHGEKNYPFRKEASDLDVGLPDGCGDAAYLEALAGALDTLAARFAPRLIIYLAGADPHE
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCC
GDRLGRLRLTMDGLARRDRQVFDFAFLRRIPIAVTMAGGYGNNIDDTVAVHAQTIALAAL
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHH
HAARWAAGEAATSVSSSSLPLSA
HHHHHHCCHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]