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The map label for this gene is aspC [H]

Identifier: 17545815

GI number: 17545815

Start: 1154015

End: 1155226

Strand: Direct

Name: aspC [H]

Synonym: RSc1096

Alternate gene names: 17545815

Gene position: 1154015-1155226 (Clockwise)

Preceding gene: 17545814

Following gene: 17545816

Centisome position: 31.05

GC content: 69.31

Gene sequence:

>1212_bases
ATGCATGCCATGTTGTCTTCGAAGGTATCGACCCTGGCCCCATCCCCGATCCAGCTGATGGCCGCGAGAACGCGCGAGGC
GCGTGAGGCCGGCCGGGACGTGGTCGATCTCACGCTCGGCGAGCCCGACTTCGCCACGCCCGAGCACATCTGCGAAGCCG
CGCGGCGGGCGATCGCCGACGGCCTGACGAAATACACGCCGATCAGCGGACTGGCGCGCCTGCGGGAAGCGGTCGCCCGC
AAGTTTCGCGACGAAAACGGCATCGAATGCACGGCGGCCGAGACCCTCGTCGGCTGCGGCGGCAAGCAGGTGATTTACCA
GGCGTTCGTCGCCACCATCGATCCTGGCGATGAAGTCCTGATCCCGGCACCGTACTGGTCGTCCTACGCCGACATCGTGA
CCCTGTGCGGCGGCATCGTGAAGCCGCTTCCGACCACGCCCGAGAGCGGCTACGCACTGCAGCCGCAGACGCTGGCCGCG
GGCATTTCGGCGCGGACCAAATGGCTCGTGCTGAATGCGCCGAGCAATCCCAGCGGAACCGCCTACACCGCGGCGCAGCT
GGAGGCCTTTGCCGAAGTCCTGCGCCGCAGCGGCAACCCGCGCCTGCTCATTCTCGCCGACGACATCTACGAGCACATCG
TCTTCGATGGCCTGCGGTTCGCATCCTTTACCGCCGTCGCGCCGGATCTGCGGCACCGCACGCTGACGGTCAACGGCGTG
TCCAAGGCGTACGCTATGACGGGCTGGCGCGTCGGCTACGGCTGCGGGCCGAAGCCGCTGATCGATGCGATGGCGAACGT
GCAGATGCAGGTCAATTCCCATACCGCCTCCATCTCGCAGGCCGCCGCGATCGCCGCGCTCGAGGGGCCGCAGGACGAGC
TGGCGCGCCGGCGCGCCATCTTCGAGCAGCGCCGCGACAGCCTACTGAGCCGCCTGGGCGGCATCGCGGGCCTGCGCACC
CCGCGTCCGCAGGGCGCGTTCTATCTGTTCCCGGACGCGCAGGCCTTCATCGGCCGACGCACGCCCGAAGGGTGCGCCAT
CGACGACGACCAGGCGCTCGCCGCCTATCTGCTGGACAGCGGCGTCGCGGTGGTCCCGGGTTCGGGTTTCGGCATGCCGG
GTTGCCTGCGCCTGTCGTACGCGACATCGGAGGCGCGGCTCGAGCTGGCGGCAACGCGACTTGCCGGCGCGCTGCGCAGG
CTCGGCGACTGA

Upstream 100 bases:

>100_bases
GTCGTGACCGCGGGGCTGATGGCGCTGCGGCCGCTGCTCTGAGGCCGGCCGGCGCCGCGCGCCATCCGGCTTTCCGTATC
AACGAAACAGGAACGCACTC

Downstream 100 bases:

>100_bases
TCTGGGGTGAAGGCAATGTTGAATATAAGCATCGCCTTTTGAGGCTTTTATAGCGTCGAGTATTAGTCATCAGGCGGGCA
TGCTGCTCGCCATGACTGCC

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MHAMLSSKVSTLAPSPIQLMAARTREAREAGRDVVDLTLGEPDFATPEHICEAARRAIADGLTKYTPISGLARLREAVAR
KFRDENGIECTAAETLVGCGGKQVIYQAFVATIDPGDEVLIPAPYWSSYADIVTLCGGIVKPLPTTPESGYALQPQTLAA
GISARTKWLVLNAPSNPSGTAYTAAQLEAFAEVLRRSGNPRLLILADDIYEHIVFDGLRFASFTAVAPDLRHRTLTVNGV
SKAYAMTGWRVGYGCGPKPLIDAMANVQMQVNSHTASISQAAAIAALEGPQDELARRRAIFEQRRDSLLSRLGGIAGLRT
PRPQGAFYLFPDAQAFIGRRTPEGCAIDDDQALAAYLLDSGVAVVPGSGFGMPGCLRLSYATSEARLELAATRLAGALRR
LGD

Sequences:

>Translated_403_residues
MHAMLSSKVSTLAPSPIQLMAARTREAREAGRDVVDLTLGEPDFATPEHICEAARRAIADGLTKYTPISGLARLREAVAR
KFRDENGIECTAAETLVGCGGKQVIYQAFVATIDPGDEVLIPAPYWSSYADIVTLCGGIVKPLPTTPESGYALQPQTLAA
GISARTKWLVLNAPSNPSGTAYTAAQLEAFAEVLRRSGNPRLLILADDIYEHIVFDGLRFASFTAVAPDLRHRTLTVNGV
SKAYAMTGWRVGYGCGPKPLIDAMANVQMQVNSHTASISQAAAIAALEGPQDELARRRAIFEQRRDSLLSRLGGIAGLRT
PRPQGAFYLFPDAQAFIGRRTPEGCAIDDDQALAAYLLDSGVAVVPGSGFGMPGCLRLSYATSEARLELAATRLAGALRR
LGD
>Mature_403_residues
MHAMLSSKVSTLAPSPIQLMAARTREAREAGRDVVDLTLGEPDFATPEHICEAARRAIADGLTKYTPISGLARLREAVAR
KFRDENGIECTAAETLVGCGGKQVIYQAFVATIDPGDEVLIPAPYWSSYADIVTLCGGIVKPLPTTPESGYALQPQTLAA
GISARTKWLVLNAPSNPSGTAYTAAQLEAFAEVLRRSGNPRLLILADDIYEHIVFDGLRFASFTAVAPDLRHRTLTVNGV
SKAYAMTGWRVGYGCGPKPLIDAMANVQMQVNSHTASISQAAAIAALEGPQDELARRRAIFEQRRDSLLSRLGGIAGLRT
PRPQGAFYLFPDAQAFIGRRTPEGCAIDDDQALAAYLLDSGVAVVPGSGFGMPGCLRLSYATSEARLELAATRLAGALRR
LGD

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=394, Percent_Identity=28.9340101522843, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI169881279, Length=394, Percent_Identity=28.9340101522843, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI56713254, Length=327, Percent_Identity=28.1345565749235, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI56713256, Length=327, Percent_Identity=28.1345565749235, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI169881281, Length=393, Percent_Identity=24.9363867684478, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI4507369, Length=394, Percent_Identity=22.5888324873096, Blast_Score=106, Evalue=5e-23,
Organism=Escherichia coli, GI1786816, Length=394, Percent_Identity=30.2030456852792, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788722, Length=386, Percent_Identity=29.7927461139896, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1788627, Length=366, Percent_Identity=28.4153005464481, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1790797, Length=390, Percent_Identity=25.6410256410256, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71994476, Length=438, Percent_Identity=25.7990867579909, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI71994472, Length=438, Percent_Identity=25.7990867579909, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17567663, Length=381, Percent_Identity=24.6719160104987, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17567369, Length=326, Percent_Identity=27.3006134969325, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI71981209, Length=380, Percent_Identity=23.4210526315789, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=410, Percent_Identity=23.4146341463415, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323118, Length=355, Percent_Identity=24.7887323943662, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28573069, Length=324, Percent_Identity=25.3086419753086, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24646114, Length=324, Percent_Identity=25.3086419753086, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28573067, Length=324, Percent_Identity=25.3086419753086, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28573065, Length=324, Percent_Identity=25.3086419753086, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI18859735, Length=411, Percent_Identity=24.330900243309, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI45551451, Length=389, Percent_Identity=24.9357326478149, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641770, Length=389, Percent_Identity=24.9357326478149, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641760, Length=389, Percent_Identity=24.9357326478149, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641768, Length=389, Percent_Identity=24.9357326478149, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641766, Length=389, Percent_Identity=24.9357326478149, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641764, Length=389, Percent_Identity=24.9357326478149, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43000; Mature: 43000

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAMLSSKVSTLAPSPIQLMAARTREAREAGRDVVDLTLGEPDFATPEHICEAARRAIAD
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
GLTKYTPISGLARLREAVARKFRDENGIECTAAETLVGCGGKQVIYQAFVATIDPGDEVL
HHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHCCCCHHHHHHHHHHEECCCCCEE
IPAPYWSSYADIVTLCGGIVKPLPTTPESGYALQPQTLAAGISARTKWLVLNAPSNPSGT
EECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCHHHHHCCCCCEEEEEEECCCCCCCC
AYTAAQLEAFAEVLRRSGNPRLLILADDIYEHIVFDGLRFASFTAVAPDLRHRTLTVNGV
CHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEECCC
SKAYAMTGWRVGYGCGPKPLIDAMANVQMQVNSHTASISQAAAIAALEGPQDELARRRAI
HHHHHHCCCEECCCCCCHHHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHH
FEQRRDSLLSRLGGIAGLRTPRPQGAFYLFPDAQAFIGRRTPEGCAIDDDQALAAYLLDS
HHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCHHHHHCCCCCCCCCCCCHHHHHHHHHHC
GVAVVPGSGFGMPGCLRLSYATSEARLELAATRLAGALRRLGD
CCEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHAMLSSKVSTLAPSPIQLMAARTREAREAGRDVVDLTLGEPDFATPEHICEAARRAIAD
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
GLTKYTPISGLARLREAVARKFRDENGIECTAAETLVGCGGKQVIYQAFVATIDPGDEVL
HHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHCCCCHHHHHHHHHHEECCCCCEE
IPAPYWSSYADIVTLCGGIVKPLPTTPESGYALQPQTLAAGISARTKWLVLNAPSNPSGT
EECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEECCHHHHHCCCCCEEEEEEECCCCCCCC
AYTAAQLEAFAEVLRRSGNPRLLILADDIYEHIVFDGLRFASFTAVAPDLRHRTLTVNGV
CHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEECCC
SKAYAMTGWRVGYGCGPKPLIDAMANVQMQVNSHTASISQAAAIAALEGPQDELARRRAI
HHHHHHCCCEECCCCCCHHHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHH
FEQRRDSLLSRLGGIAGLRTPRPQGAFYLFPDAQAFIGRRTPEGCAIDDDQALAAYLLDS
HHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCHHHHHCCCCCCCCCCCCHHHHHHHHHHC
GVAVVPGSGFGMPGCLRLSYATSEARLELAATRLAGALRRLGD
CCEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]