Click here to switch to the map view.

The map label for this gene is nahR [H]

Identifier: 17545811

GI number: 17545811

Start: 1149306

End: 1150208

Strand: Direct

Name: nahR [H]

Synonym: RSc1092

Alternate gene names: 17545811

Gene position: 1149306-1150208 (Clockwise)

Preceding gene: 17545802

Following gene: 17545813

Centisome position: 30.93

GC content: 66.0

Gene sequence:

>903_bases
ATGGAACTGCAAGACATCGACCTCAACCTGCTGGTCGTCTTCAACGAATTGCTCAGGCAGCGGCGCGTTTCGGCCGTCGC
CGAGACCCTCGGCATCACGCAGCCGGCGATCAGCAATGCGCTGAACCGGCTGCGCAAGCTGCTGGGGGATGAACTGTTCG
TCCGCACATCGAAAGGGATGATCCCGACGCCGTTTGCCGAGACGCTCGCCGAGCCGATCGCCTACGCGCTCGGGGCGATC
TACAACTCGCTCAACGCCACCTCCAGGTTCGAGCCCGCCACCAGCACGCGCGCCTTCACGATCGCGATGACGGACATCGG
CGAGATCTATTTCCTGCCGACGCTGATGCGCCGGCTGGCCAGGGACGCGCCCGGCGTCACGGTCAGTACGGTGCGCAACC
ACGCCGATACGTTGCGCGATGAGATGGAAGCGGGGCGCGTGGACCTGGCGATCGGTTTCCTGCCCGACCTGAAGTCGGGC
TTCTTCCAGCGCCGGCTGTTCCGGCAGCGCTATGTGTGCCTGTTCCGCAAGGGCCATCCGCTGGCCAAGCGCGGCATGAC
GATGGAGGGTTTTCTGGAGGCCGAGCATGTGTCGATCGTCGCGGAAGGCACCGGCCACGGCATGGTGGACGCGACGATCC
TGCGCGCCGGCCTGCCGCGGCGCGTGAGCCTGCATGTGCCGCACTTCATCGCGCTCGGGCACATCCTGCAGTCGACCGAC
CTGATCGCGGTGGTCCCGCAGGCGTACGCGACGCGCACGCTCAAGCCGTTCGGCCTCGACACGGCCGCGTGTCCGGTCAA
AATTCCGGACATCACCATCAACGTGCTCTGGCACGCGCGCAACCACCGCGAGCCCGGGAACCAGTGGCTGCGGCAGTTGC
TGTTCGAGACCTTTGCGATCTAG

Upstream 100 bases:

>100_bases
GTGGACGCATCATGACGCGCTTGACGCCATCCATAAATAGAAGCAACCTGATGTGTCATATCACTCGCAGTGATAATGCG
AGACGGCGAGGAGACACGCC

Downstream 100 bases:

>100_bases
CGAAAATGCGGCGGGCAGTCCGCCACGCAGGCGGCGCTGCCCGCGCGACGGCTCGATGATGCGATGGCTCAGGCGCCTTC
GGTGACGGCGGGCAGGGCGC

Product: transcriptional regulatory DNA-binding transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MELQDIDLNLLVVFNELLRQRRVSAVAETLGITQPAISNALNRLRKLLGDELFVRTSKGMIPTPFAETLAEPIAYALGAI
YNSLNATSRFEPATSTRAFTIAMTDIGEIYFLPTLMRRLARDAPGVTVSTVRNHADTLRDEMEAGRVDLAIGFLPDLKSG
FFQRRLFRQRYVCLFRKGHPLAKRGMTMEGFLEAEHVSIVAEGTGHGMVDATILRAGLPRRVSLHVPHFIALGHILQSTD
LIAVVPQAYATRTLKPFGLDTAACPVKIPDITINVLWHARNHREPGNQWLRQLLFETFAI

Sequences:

>Translated_300_residues
MELQDIDLNLLVVFNELLRQRRVSAVAETLGITQPAISNALNRLRKLLGDELFVRTSKGMIPTPFAETLAEPIAYALGAI
YNSLNATSRFEPATSTRAFTIAMTDIGEIYFLPTLMRRLARDAPGVTVSTVRNHADTLRDEMEAGRVDLAIGFLPDLKSG
FFQRRLFRQRYVCLFRKGHPLAKRGMTMEGFLEAEHVSIVAEGTGHGMVDATILRAGLPRRVSLHVPHFIALGHILQSTD
LIAVVPQAYATRTLKPFGLDTAACPVKIPDITINVLWHARNHREPGNQWLRQLLFETFAI
>Mature_300_residues
MELQDIDLNLLVVFNELLRQRRVSAVAETLGITQPAISNALNRLRKLLGDELFVRTSKGMIPTPFAETLAEPIAYALGAI
YNSLNATSRFEPATSTRAFTIAMTDIGEIYFLPTLMRRLARDAPGVTVSTVRNHADTLRDEMEAGRVDLAIGFLPDLKSG
FFQRRLFRQRYVCLFRKGHPLAKRGMTMEGFLEAEHVSIVAEGTGHGMVDATILRAGLPRRVSLHVPHFIALGHILQSTD
LIAVVPQAYATRTLKPFGLDTAACPVKIPDITINVLWHARNHREPGNQWLRQLLFETFAI

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=301, Percent_Identity=25.2491694352159, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87081766, Length=248, Percent_Identity=24.5967741935484, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790147, Length=302, Percent_Identity=23.841059602649, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1786820, Length=246, Percent_Identity=23.9837398373984, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33480; Mature: 33480

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELQDIDLNLLVVFNELLRQRRVSAVAETLGITQPAISNALNRLRKLLGDELFVRTSKGM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCC
IPTPFAETLAEPIAYALGAIYNSLNATSRFEPATSTRAFTIAMTDIGEIYFLPTLMRRLA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHH
RDAPGVTVSTVRNHADTLRDEMEAGRVDLAIGFLPDLKSGFFQRRLFRQRYVCLFRKGHP
HCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCC
LAKRGMTMEGFLEAEHVSIVAEGTGHGMVDATILRAGLPRRVSLHVPHFIALGHILQSTD
HHHHCCCHHHHHHHCEEEEEEECCCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCC
LIAVVPQAYATRTLKPFGLDTAACPVKIPDITINVLWHARNHREPGNQWLRQLLFETFAI
CEEECCHHHHHCCCCCCCCCCCCCCEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELQDIDLNLLVVFNELLRQRRVSAVAETLGITQPAISNALNRLRKLLGDELFVRTSKGM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEECCCC
IPTPFAETLAEPIAYALGAIYNSLNATSRFEPATSTRAFTIAMTDIGEIYFLPTLMRRLA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHH
RDAPGVTVSTVRNHADTLRDEMEAGRVDLAIGFLPDLKSGFFQRRLFRQRYVCLFRKGHP
HCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCC
LAKRGMTMEGFLEAEHVSIVAEGTGHGMVDATILRAGLPRRVSLHVPHFIALGHILQSTD
HHHHCCCHHHHHHHCEEEEEEECCCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCC
LIAVVPQAYATRTLKPFGLDTAACPVKIPDITINVLWHARNHREPGNQWLRQLLFETFAI
CEEECCHHHHHCCCCCCCCCCCCCCEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]