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The map label for this gene is 17545638

Identifier: 17545638

GI number: 17545638

Start: 970704

End: 971627

Strand: Direct

Name: 17545638

Synonym: RSc0919

Alternate gene names: NA

Gene position: 970704-971627 (Clockwise)

Preceding gene: 17545636

Following gene: 17545639

Centisome position: 26.12

GC content: 66.99

Gene sequence:

>924_bases
ATGGCGACCGGCCTCTACACGCATCCTGAATTCCTCAAGCACGAGATGGGGCACCACCATCCCGAGTGTCCCGACCGCCT
GCGTGCGATCGAAGATCAACTGATCGCGAGCCGCATCGAGCAGTTCCTCGTGCCATGCGAGGCACCGCCGGCCACCGAGG
CGCAGCTGTGCCGCGTGCATCGTCCCGAATACGTGCGCGAACTGGTCGCCAGCGTGCCGATCGCCGGTTATGCGCCGATC
GATCCCGACACGGCGATGAACCCGCACACCTACATGGCGGCGGTGCTGGCGGCCGGCGCAGCGGTGCAGGCCACCGACAA
GGTGATCGCCGGCGCGCTGGAGAACGCCTTCTGCTGTGTGCGTCCACCCGGCCATCATGCCGAGCCGGGCCGGGCCATGG
GGTTCTGCTTCTTCAACAATGTGGCCGTGGCCGCGCGCCATGCGCTGGATCATCACGGGCTCGCACGCGTGGCCATCGTC
GACTTCGACGTCCACCACGGCAACGGCACCGAAGCGGCCTTCCGCGACGAGCCGCGCGTGCTGATGTGCAGCTTCTTCCA
GCACCCGTTCTATCCGTATTCCGGCACGGAGGGCGTGGCGGCCAACATGGTCAACATCCCGTTGCCGGCCTACACCAACG
GCCTGACCGTGCGCGAAGTGGTCGAGACGATCTGGCTGCCGCGCCTGGACGCATTCCGGCCCGAGATGCTGTTCATTTCC
GCCGGCTTCGATGCGCACCGCGAGGACGATCTCGGCCAGATGGGCCTGGTCGAGGCGGACTACGCCTGGATTACCCGGCA
ACTGATGCAGGTGGCGCGCGCACATGCCAAGGGCCGCATCGTCAGCTGCCTGGAAGGCGGCTACAACCTGAGCGCGCTCG
GGCGTAGCGTGGTGGCCCACGTGAAGGCCCTGGCCGAGCTATGA

Upstream 100 bases:

>100_bases
GACCGGGGCATTGTAGCGGATGGGTCCGCCGGCCGCCCCGGCACGGCCGTGCTAACGTAACGGCTGGAGACACCACGACG
CACCGGCACACAACACCAAC

Downstream 100 bases:

>100_bases
AGACGAATTGTCCTCAACATTTGTAAAAGTAATAAAGACATCGTCAAAAAATCGTTCAGCGCATGTAGGGCCTGCCTTAC
ACTAGCGCCTCATTCCAACG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MATGLYTHPEFLKHEMGHHHPECPDRLRAIEDQLIASRIEQFLVPCEAPPATEAQLCRVHRPEYVRELVASVPIAGYAPI
DPDTAMNPHTYMAAVLAAGAAVQATDKVIAGALENAFCCVRPPGHHAEPGRAMGFCFFNNVAVAARHALDHHGLARVAIV
DFDVHHGNGTEAAFRDEPRVLMCSFFQHPFYPYSGTEGVAANMVNIPLPAYTNGLTVREVVETIWLPRLDAFRPEMLFIS
AGFDAHREDDLGQMGLVEADYAWITRQLMQVARAHAKGRIVSCLEGGYNLSALGRSVVAHVKALAEL

Sequences:

>Translated_307_residues
MATGLYTHPEFLKHEMGHHHPECPDRLRAIEDQLIASRIEQFLVPCEAPPATEAQLCRVHRPEYVRELVASVPIAGYAPI
DPDTAMNPHTYMAAVLAAGAAVQATDKVIAGALENAFCCVRPPGHHAEPGRAMGFCFFNNVAVAARHALDHHGLARVAIV
DFDVHHGNGTEAAFRDEPRVLMCSFFQHPFYPYSGTEGVAANMVNIPLPAYTNGLTVREVVETIWLPRLDAFRPEMLFIS
AGFDAHREDDLGQMGLVEADYAWITRQLMQVARAHAKGRIVSCLEGGYNLSALGRSVVAHVKALAEL
>Mature_306_residues
ATGLYTHPEFLKHEMGHHHPECPDRLRAIEDQLIASRIEQFLVPCEAPPATEAQLCRVHRPEYVRELVASVPIAGYAPID
PDTAMNPHTYMAAVLAAGAAVQATDKVIAGALENAFCCVRPPGHHAEPGRAMGFCFFNNVAVAARHALDHHGLARVAIVD
FDVHHGNGTEAAFRDEPRVLMCSFFQHPFYPYSGTEGVAANMVNIPLPAYTNGLTVREVVETIWLPRLDAFRPEMLFISA
GFDAHREDDLGQMGLVEADYAWITRQLMQVARAHAKGRIVSCLEGGYNLSALGRSVVAHVKALAEL

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI20070354, Length=326, Percent_Identity=37.7300613496933, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI13128864, Length=322, Percent_Identity=37.5776397515528, Blast_Score=168, Evalue=4e-42,
Organism=Homo sapiens, GI226529806, Length=323, Percent_Identity=35.2941176470588, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI17158039, Length=352, Percent_Identity=32.6704545454545, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI30795202, Length=352, Percent_Identity=32.6704545454545, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI30795204, Length=352, Percent_Identity=32.6704545454545, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI153085395, Length=253, Percent_Identity=39.5256916996047, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI62750347, Length=258, Percent_Identity=36.4341085271318, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI62750349, Length=258, Percent_Identity=36.4341085271318, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI169234807, Length=255, Percent_Identity=36.078431372549, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI148539870, Length=255, Percent_Identity=36.078431372549, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI13128862, Length=271, Percent_Identity=23.6162361623616, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI293336691, Length=266, Percent_Identity=24.4360902255639, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI13128860, Length=258, Percent_Identity=24.031007751938, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI217272877, Length=248, Percent_Identity=25.4032258064516, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI193209491, Length=345, Percent_Identity=33.3333333333333, Blast_Score=154, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI17540334, Length=308, Percent_Identity=34.4155844155844, Blast_Score=151, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17540332, Length=308, Percent_Identity=34.4155844155844, Blast_Score=150, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI193206283, Length=308, Percent_Identity=34.4155844155844, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI25154020, Length=299, Percent_Identity=32.7759197324415, Blast_Score=149, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI25154022, Length=299, Percent_Identity=32.1070234113712, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17537347, Length=306, Percent_Identity=33.9869281045752, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17534739, Length=307, Percent_Identity=25.4071661237785, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17508561, Length=267, Percent_Identity=26.5917602996255, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17561978, Length=256, Percent_Identity=25.390625, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324307, Length=317, Percent_Identity=32.1766561514196, Blast_Score=146, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6323999, Length=257, Percent_Identity=27.6264591439689, Blast_Score=93, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6325141, Length=287, Percent_Identity=25.7839721254355, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6321244, Length=260, Percent_Identity=28.0769230769231, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6325325, Length=257, Percent_Identity=25.2918287937743, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281360899, Length=307, Percent_Identity=35.8306188925081, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24642146, Length=307, Percent_Identity=35.8306188925081, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24642144, Length=307, Percent_Identity=35.8306188925081, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24642142, Length=307, Percent_Identity=35.8306188925081, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI281360799, Length=343, Percent_Identity=35.5685131195335, Blast_Score=151, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24641720, Length=343, Percent_Identity=35.5685131195335, Blast_Score=151, Evalue=6e-37,
Organism=Drosophila melanogaster, GI281360801, Length=343, Percent_Identity=35.5685131195335, Blast_Score=151, Evalue=7e-37,
Organism=Drosophila melanogaster, GI24657891, Length=273, Percent_Identity=27.8388278388278, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24644244, Length=262, Percent_Identity=24.4274809160305, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649807, Length=261, Percent_Identity=27.5862068965517, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33647; Mature: 33516

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGLYTHPEFLKHEMGHHHPECPDRLRAIEDQLIASRIEQFLVPCEAPPATEAQLCRVH
CCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHC
RPEYVRELVASVPIAGYAPIDPDTAMNPHTYMAAVLAAGAAVQATDKVIAGALENAFCCV
CHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEE
RPPGHHAEPGRAMGFCFFNNVAVAARHALDHHGLARVAIVDFDVHHGNGTEAAFRDEPRV
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCCCCCE
LMCSFFQHPFYPYSGTEGVAANMVNIPLPAYTNGLTVREVVETIWLPRLDAFRPEMLFIS
EHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEE
AGFDAHREDDLGQMGLVEADYAWITRQLMQVARAHAKGRIVSCLEGGYNLSALGRSVVAH
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCCHHHHHHHHHHH
VKALAEL
HHHHHCC
>Mature Secondary Structure 
ATGLYTHPEFLKHEMGHHHPECPDRLRAIEDQLIASRIEQFLVPCEAPPATEAQLCRVH
CCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHC
RPEYVRELVASVPIAGYAPIDPDTAMNPHTYMAAVLAAGAAVQATDKVIAGALENAFCCV
CHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEE
RPPGHHAEPGRAMGFCFFNNVAVAARHALDHHGLARVAIVDFDVHHGNGTEAAFRDEPRV
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCCCCCE
LMCSFFQHPFYPYSGTEGVAANMVNIPLPAYTNGLTVREVVETIWLPRLDAFRPEMLFIS
EHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEE
AGFDAHREDDLGQMGLVEADYAWITRQLMQVARAHAKGRIVSCLEGGYNLSALGRSVVAH
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCCHHHHHHHHHHH
VKALAEL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]