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The map label for this gene is serC [H]

Identifier: 17545622

GI number: 17545622

Start: 953903

End: 955039

Strand: Direct

Name: serC [H]

Synonym: RSc0903

Alternate gene names: 17545622

Gene position: 953903-955039 (Clockwise)

Preceding gene: 17545621

Following gene: 17545623

Centisome position: 25.67

GC content: 64.03

Gene sequence:

>1137_bases
ATGAACCAAGCGGATCGAGCTCTTCAAGCCAGCCAGGCGCGTGTCTACAACTTTTCGGCGGGGCCGGCCGTGCTGCCGAC
CGAGGTGCTGGAGCAGGCAAGGGAAGAGATGCTCTCTTGGCAAGGCAGCGGCATGAGCGTGATGGAGATGAGCCATCGCG
GCCGCGAGTTCGAAAGCATCATGGCGCAGGCATTCGCCGATTTGCGCGAATTGCTGGCGGTGCCCGACAACTACGAGATC
CTGTTCCTGCAGGGCGGCGCCATCGCCGAGAATGCCATCGTCCCGCTCAATCTGATGCGCCGGCTGTCGCTCGACGCGCC
CAAGGCGGATTACGTCGTGACCGGCACGTGGTCGGTGAAGTCGCAGCAGGAAGCGCGCAAATACGGTGAAGTGAATATCG
CCGCATCGAGCGAGGCCGAGCGTTTCCACCGGATCCCGGATGTGTCCGCCTGGAAGCTGTCGGATGACGCGGCTTACGTG
CATCTGTGCACCAACGAGACCATCGTCGGCGTCGAATACCAGGAGACGCCGGACATTGGCCAGGCGCATGGGCGCGTGGT
GGTGGCCGATGTTTCGAGCCACATTCTGTCGCGGCCGGTCGACTGGAACGGCTATGCGGTGCTTTACGGCGGCGCGCAGA
AGAACATCGGGCCGGCGGGCCTGACCATCGTGATCGCGCGCAAGGATCTGCTGGGCCACGCGCACCCGCTGTGCCCGTCG
GCCTTCAACTGGCGCCTGGTGGCCGAGAACGGCTCGATGTACAACACGCCGCCCACCTACGCCATCTATGTCGCCGGACT
GGTGTTCCAGTGGATCAAGCGCCAGGGCGGCGTGGAGGCGCTGGAGACCCGCAACATCGTCAAGGCGAAGATGCTGTACG
ACTTCATCGACGCCAGCGGTTTCTATCGCAACGACATTCATCCGTCGTGCCGTTCGCGCATGAATGTGCCGTTCTTCCTC
AACGACGAATCCCGCAACGAAGCCTTCCTCGCGCAGGCGCGCGCGCAAGGGCTGGTGCAGCTCAAGGGCCACAAGTCCGT
GGGCGGCATGCGGGCGAGCATCTACAACGCGATGCCGCTGGAGGGCGTGGAGGCGCTGGTCGACTTCATGCGCGAATTCG
AGCGGACCGCCGCCTGA

Upstream 100 bases:

>100_bases
CCGATGATCGGCGCGCGATCCCCGTCGCGCCGCTGATTGATGGATAATGGCTGTTTGGGTTTGCGCCCAGACAGCCATTT
TTCTTTTGCCCCTTTGTCCC

Downstream 100 bases:

>100_bases
GCCGCGCGCCGCAATCACGGCAGAACATTGCGCAAAGCCCCTGCTTTGCGCGGCAATTAGCAATCTGTTGCCGAACCCGA
TCTCTACAATGACCAGTCAG

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MNQADRALQASQARVYNFSAGPAVLPTEVLEQAREEMLSWQGSGMSVMEMSHRGREFESIMAQAFADLRELLAVPDNYEI
LFLQGGAIAENAIVPLNLMRRLSLDAPKADYVVTGTWSVKSQQEARKYGEVNIAASSEAERFHRIPDVSAWKLSDDAAYV
HLCTNETIVGVEYQETPDIGQAHGRVVVADVSSHILSRPVDWNGYAVLYGGAQKNIGPAGLTIVIARKDLLGHAHPLCPS
AFNWRLVAENGSMYNTPPTYAIYVAGLVFQWIKRQGGVEALETRNIVKAKMLYDFIDASGFYRNDIHPSCRSRMNVPFFL
NDESRNEAFLAQARAQGLVQLKGHKSVGGMRASIYNAMPLEGVEALVDFMREFERTAA

Sequences:

>Translated_378_residues
MNQADRALQASQARVYNFSAGPAVLPTEVLEQAREEMLSWQGSGMSVMEMSHRGREFESIMAQAFADLRELLAVPDNYEI
LFLQGGAIAENAIVPLNLMRRLSLDAPKADYVVTGTWSVKSQQEARKYGEVNIAASSEAERFHRIPDVSAWKLSDDAAYV
HLCTNETIVGVEYQETPDIGQAHGRVVVADVSSHILSRPVDWNGYAVLYGGAQKNIGPAGLTIVIARKDLLGHAHPLCPS
AFNWRLVAENGSMYNTPPTYAIYVAGLVFQWIKRQGGVEALETRNIVKAKMLYDFIDASGFYRNDIHPSCRSRMNVPFFL
NDESRNEAFLAQARAQGLVQLKGHKSVGGMRASIYNAMPLEGVEALVDFMREFERTAA
>Mature_378_residues
MNQADRALQASQARVYNFSAGPAVLPTEVLEQAREEMLSWQGSGMSVMEMSHRGREFESIMAQAFADLRELLAVPDNYEI
LFLQGGAIAENAIVPLNLMRRLSLDAPKADYVVTGTWSVKSQQEARKYGEVNIAASSEAERFHRIPDVSAWKLSDDAAYV
HLCTNETIVGVEYQETPDIGQAHGRVVVADVSSHILSRPVDWNGYAVLYGGAQKNIGPAGLTIVIARKDLLGHAHPLCPS
AFNWRLVAENGSMYNTPPTYAIYVAGLVFQWIKRQGGVEALETRNIVKAKMLYDFIDASGFYRNDIHPSCRSRMNVPFFL
NDESRNEAFLAQARAQGLVQLKGHKSVGGMRASIYNAMPLEGVEALVDFMREFERTAA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=366, Percent_Identity=46.9945355191257, Blast_Score=347, Evalue=1e-95,
Organism=Homo sapiens, GI10863955, Length=362, Percent_Identity=43.3701657458564, Blast_Score=299, Evalue=3e-81,
Organism=Escherichia coli, GI1787136, Length=364, Percent_Identity=53.5714285714286, Blast_Score=392, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17506897, Length=372, Percent_Identity=44.6236559139785, Blast_Score=325, Evalue=3e-89,
Organism=Saccharomyces cerevisiae, GI6324758, Length=387, Percent_Identity=41.8604651162791, Blast_Score=279, Evalue=4e-76,
Organism=Drosophila melanogaster, GI21356589, Length=366, Percent_Identity=46.9945355191257, Blast_Score=342, Evalue=2e-94,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 41861; Mature: 41861

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQADRALQASQARVYNFSAGPAVLPTEVLEQAREEMLSWQGSGMSVMEMSHRGREFESI
CCHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHH
MAQAFADLRELLAVPDNYEILFLQGGAIAENAIVPLNLMRRLSLDAPKADYVVTGTWSVK
HHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEHHHHHHHHCCCCCCCCEEEEEEECCC
SQQEARKYGEVNIAASSEAERFHRIPDVSAWKLSDDAAYVHLCTNETIVGVEYQETPDIG
CHHHHHHCCCEEEEECCHHHHHHCCCCCCEEEECCCCEEEEEECCCEEEEEEECCCCCCC
QAHGRVVVADVSSHILSRPVDWNGYAVLYGGAQKNIGPAGLTIVIARKDLLGHAHPLCPS
CCCCEEEEEECHHHHHCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEHHHHCCCCCCCCC
AFNWRLVAENGSMYNTPPTYAIYVAGLVFQWIKRQGGVEALETRNIVKAKMLYDFIDASG
CCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
FYRNDIHPSCRSRMNVPFFLNDESRNEAFLAQARAQGLVQLKGHKSVGGMRASIYNAMPL
CCCCCCCHHHHHCCCCCEEECCCCCCHHHHHHHHHCCEEEEECCCCCCCHHHHHHCCCCH
EGVEALVDFMREFERTAA
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNQADRALQASQARVYNFSAGPAVLPTEVLEQAREEMLSWQGSGMSVMEMSHRGREFESI
CCHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHH
MAQAFADLRELLAVPDNYEILFLQGGAIAENAIVPLNLMRRLSLDAPKADYVVTGTWSVK
HHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEHHHHHHHHCCCCCCCCEEEEEEECCC
SQQEARKYGEVNIAASSEAERFHRIPDVSAWKLSDDAAYVHLCTNETIVGVEYQETPDIG
CHHHHHHCCCEEEEECCHHHHHHCCCCCCEEEECCCCEEEEEECCCEEEEEEECCCCCCC
QAHGRVVVADVSSHILSRPVDWNGYAVLYGGAQKNIGPAGLTIVIARKDLLGHAHPLCPS
CCCCEEEEEECHHHHHCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEHHHHCCCCCCCCC
AFNWRLVAENGSMYNTPPTYAIYVAGLVFQWIKRQGGVEALETRNIVKAKMLYDFIDASG
CCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
FYRNDIHPSCRSRMNVPFFLNDESRNEAFLAQARAQGLVQLKGHKSVGGMRASIYNAMPL
CCCCCCCHHHHHCCCCCEEECCCCCCHHHHHHHHHCCEEEEECCCCCCCHHHHHHCCCCH
EGVEALVDFMREFERTAA
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA