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The map label for this gene is hpmB [H]

Identifier: 17545607

GI number: 17545607

Start: 933257

End: 935029

Strand: Direct

Name: hpmB [H]

Synonym: RSc0888

Alternate gene names: 17545607

Gene position: 933257-935029 (Clockwise)

Preceding gene: 17545606

Following gene: 17545608

Centisome position: 25.11

GC content: 64.69

Gene sequence:

>1773_bases
ATGCAATACAAGAAAAAATCACTGCCGCTCGCACTCGGTGCGGTCGGTTTTCTGATGTCACATCTTCCAGCCGACGTCTT
CGCCCAAACACCCCCCACCCAGTCGGCAGCCACTGCAACCGCCAACACAGAACAGGAACAACGGCTGCGCCAACAGCAAC
AAGCCCGCGAACGCGAGCAAGCCGTGCAGGCCCCCGCAGTCCGCGCCCAGCAAGCCGCCCCGGCCGAGTTCCCCGAACTC
CCCACCGAAACACCCTGCTTCCGCATCGACCGTTTCGCACTGGAGGTCCCGCAGGACTTGCCCGAGGCCGCCCGCACAAA
GGGCGCCTCTGCGCTGCCCCAAGACCCCTTCGCCTTCGCCCAGGCATGGCTTGACCACTACACCGGCGCCTGCGTCGGCA
AGCAAGGCGTGGACCTGCTCACCAAAGGCGTCTCGCAAGCCATCCTGAGCCGGGGCTATGTGACCACACGCGTGCTGCTG
CCCCAGCAGGACCTGAGCACCGGCACGCTGCGCTTCGTCCTGGTGCCCGGCATGATCGGGCAGATCCGTTTCGCGCAGGC
CGATGTGCGGGGCACCTGGAAATCCGCCTTCCCCTCACGCCCGGGTGACCTGCTGAACCTGCGCGACCTCGAACAGGGCC
TGGAGCAAATGAAGCGCGTCGCCAGCCAGGACGTCGACATGCAGCTCGTGCCCACGGACGTGCCGGGCGTGAGCGATGTG
GTGATCTCGGTCAAGCGCACCAAGCCCTGGACGGTCGTCGCTGCGGTGGACAACTCGGGCACGCGGTCGACGGGCAAGCT
GCAAGGCAACCTGAGCCTCAGCCTCGACAACCCGCTGGGACTGAGCGACCTGTTCAACGTGGGCTACAGCCAGGACCTGG
ATTTCAGCAACAAGGAACGTGGCACCCACGGCTGGAACGGCTTCTACTCGGTGCCGTGGGGGTACTGGACGGCGACGGTG
TCGGCGTATTCCAGCACCTACTTCCAGCAGATCGCGGGCGTCAACCAGACCTTCGTGTCGAGCGGCAATTCGCAGAACTT
CGACGTCAAGCTGCAGCGTGTCATCGAGCGTTCGCAGAACGATGTGCTGGGCGTGCAGTTCCGGCTATCCAAGCGGTTCG
GCAAGAACTTCGTCGACGACACCGAGATTCCCCAGCAGCGGCGCAACAACACGGTGGCGGAAGCCGGCCTGACGGACCGC
CATTACTTCGGGGCCGCGCAGTTCGACGGCAGCCTGCTGCTCCGCCACGGCGTGGGCGACTTCGGTGCACAGGACGACAC
GCTGGCCGACGGCGGTGGCCCGACCTGGCACTATCGCATGCTGGTGGCGGATGCCAACCTGTCGGTGCCGTTCAAGGTGG
GGACGCAGCCACTGCGGTATGTGACCACGTTCCGTGGGCAGTTCACCAACGACCATCTGTATTCGATCGACGCGATCACC
ATCGGCAGCCGCTACACCGTGCGGGGCTTCGATGGCGAGATGTCGCTGCTGGGTGATCGCGGCTTCTATTGGCGCAATGA
GCTGCAAGCGCCGATCGGCAACACCGGCCTGTCGCTCTATGGGGGGCTCGACTACGGCCATGTCTATGGCCCGTCGACGG
TGGGCTTGGCGGGCACCCAACTGGCGGGCGCAGTGATCGGGCTGCGCGGCGGATGGGGCACGTCGTATGGTTCGCTGTCC
TACGACCTGTTCATCGGTACGCCAGTCTACAAGCCAGCAGCGTTCAATACCGCCAGGATCACGACCGGGTTCCAACTGGT
CTACCAGTATTGA

Upstream 100 bases:

>100_bases
CGTAGTTGCGTGCAGGCATCCGTTGGATATTAATCTCAGCCCCGGGTCGAGTGTGATTGTCGGGGAAATTGGCGCAAGGA
TTTTGCGCCGAAAATCGAAC

Downstream 100 bases:

>100_bases
GCGACCAACACTCGCTGCACGAGATGACGAGTCAATCTGGCCCCCACCGCAAGTTCGATGCGACGCTGCCGCTGAGCGCC
GCACACCAGGCCTACCCGGA

Product: activation/secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 590; Mature: 590

Protein sequence:

>590_residues
MQYKKKSLPLALGAVGFLMSHLPADVFAQTPPTQSAATATANTEQEQRLRQQQQAREREQAVQAPAVRAQQAAPAEFPEL
PTETPCFRIDRFALEVPQDLPEAARTKGASALPQDPFAFAQAWLDHYTGACVGKQGVDLLTKGVSQAILSRGYVTTRVLL
PQQDLSTGTLRFVLVPGMIGQIRFAQADVRGTWKSAFPSRPGDLLNLRDLEQGLEQMKRVASQDVDMQLVPTDVPGVSDV
VISVKRTKPWTVVAAVDNSGTRSTGKLQGNLSLSLDNPLGLSDLFNVGYSQDLDFSNKERGTHGWNGFYSVPWGYWTATV
SAYSSTYFQQIAGVNQTFVSSGNSQNFDVKLQRVIERSQNDVLGVQFRLSKRFGKNFVDDTEIPQQRRNNTVAEAGLTDR
HYFGAAQFDGSLLLRHGVGDFGAQDDTLADGGGPTWHYRMLVADANLSVPFKVGTQPLRYVTTFRGQFTNDHLYSIDAIT
IGSRYTVRGFDGEMSLLGDRGFYWRNELQAPIGNTGLSLYGGLDYGHVYGPSTVGLAGTQLAGAVIGLRGGWGTSYGSLS
YDLFIGTPVYKPAAFNTARITTGFQLVYQY

Sequences:

>Translated_590_residues
MQYKKKSLPLALGAVGFLMSHLPADVFAQTPPTQSAATATANTEQEQRLRQQQQAREREQAVQAPAVRAQQAAPAEFPEL
PTETPCFRIDRFALEVPQDLPEAARTKGASALPQDPFAFAQAWLDHYTGACVGKQGVDLLTKGVSQAILSRGYVTTRVLL
PQQDLSTGTLRFVLVPGMIGQIRFAQADVRGTWKSAFPSRPGDLLNLRDLEQGLEQMKRVASQDVDMQLVPTDVPGVSDV
VISVKRTKPWTVVAAVDNSGTRSTGKLQGNLSLSLDNPLGLSDLFNVGYSQDLDFSNKERGTHGWNGFYSVPWGYWTATV
SAYSSTYFQQIAGVNQTFVSSGNSQNFDVKLQRVIERSQNDVLGVQFRLSKRFGKNFVDDTEIPQQRRNNTVAEAGLTDR
HYFGAAQFDGSLLLRHGVGDFGAQDDTLADGGGPTWHYRMLVADANLSVPFKVGTQPLRYVTTFRGQFTNDHLYSIDAIT
IGSRYTVRGFDGEMSLLGDRGFYWRNELQAPIGNTGLSLYGGLDYGHVYGPSTVGLAGTQLAGAVIGLRGGWGTSYGSLS
YDLFIGTPVYKPAAFNTARITTGFQLVYQY
>Mature_590_residues
MQYKKKSLPLALGAVGFLMSHLPADVFAQTPPTQSAATATANTEQEQRLRQQQQAREREQAVQAPAVRAQQAAPAEFPEL
PTETPCFRIDRFALEVPQDLPEAARTKGASALPQDPFAFAQAWLDHYTGACVGKQGVDLLTKGVSQAILSRGYVTTRVLL
PQQDLSTGTLRFVLVPGMIGQIRFAQADVRGTWKSAFPSRPGDLLNLRDLEQGLEQMKRVASQDVDMQLVPTDVPGVSDV
VISVKRTKPWTVVAAVDNSGTRSTGKLQGNLSLSLDNPLGLSDLFNVGYSQDLDFSNKERGTHGWNGFYSVPWGYWTATV
SAYSSTYFQQIAGVNQTFVSSGNSQNFDVKLQRVIERSQNDVLGVQFRLSKRFGKNFVDDTEIPQQRRNNTVAEAGLTDR
HYFGAAQFDGSLLLRHGVGDFGAQDDTLADGGGPTWHYRMLVADANLSVPFKVGTQPLRYVTTFRGQFTNDHLYSIDAIT
IGSRYTVRGFDGEMSLLGDRGFYWRNELQAPIGNTGLSLYGGLDYGHVYGPSTVGLAGTQLAGAVIGLRGGWGTSYGSLS
YDLFIGTPVYKPAAFNTARITTGFQLVYQY

Specific function: Probable member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 64536; Mature: 64536

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYKKKSLPLALGAVGFLMSHLPADVFAQTPPTQSAATATANTEQEQRLRQQQQAREREQ
CCCCCCCCCCHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AVQAPAVRAQQAAPAEFPELPTETPCFRIDRFALEVPQDLPEAARTKGASALPQDPFAFA
HHHCCHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHH
QAWLDHYTGACVGKQGVDLLTKGVSQAILSRGYVTTRVLLPQQDLSTGTLRFVLVPGMIG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEEECCCCC
QIRFAQADVRGTWKSAFPSRPGDLLNLRDLEQGLEQMKRVASQDVDMQLVPTDVPGVSDV
CEEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEE
VISVKRTKPWTVVAAVDNSGTRSTGKLQGNLSLSLDNPLGLSDLFNVGYSQDLDFSNKER
EEEEECCCCEEEEEEECCCCCCCCCEEEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCC
GTHGWNGFYSVPWGYWTATVSAYSSTYFQQIAGVNQTFVSSGNSQNFDVKLQRVIERSQN
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHCCCC
DVLGVQFRLSKRFGKNFVDDTEIPQQRRNNTVAEAGLTDRHYFGAAQFDGSLLLRHGVGD
CEEEEEEEEHHHHCCCCCCCCCCCHHHCCCCCHHCCCCCCCEECEECCCCCEEEECCCCC
FGAQDDTLADGGGPTWHYRMLVADANLSVPFKVGTQPLRYVTTFRGQFTNDHLYSIDAIT
CCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEECCCHHHHHHHHCCCCCCCCEEEEEEEE
IGSRYTVRGFDGEMSLLGDRGFYWRNELQAPIGNTGLSLYGGLDYGHVYGPSTVGLAGTQ
ECCEEEEEECCCCEEEECCCCCEEHHHCCCCCCCCCEEEECCCCCCCEECCCCCCCCHHH
LAGAVIGLRGGWGTSYGSLSYDLFIGTPVYKPAAFNTARITTGFQLVYQY
HHCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEECCEEEEEEC
>Mature Secondary Structure
MQYKKKSLPLALGAVGFLMSHLPADVFAQTPPTQSAATATANTEQEQRLRQQQQAREREQ
CCCCCCCCCCHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
AVQAPAVRAQQAAPAEFPELPTETPCFRIDRFALEVPQDLPEAARTKGASALPQDPFAFA
HHHCCHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHH
QAWLDHYTGACVGKQGVDLLTKGVSQAILSRGYVTTRVLLPQQDLSTGTLRFVLVPGMIG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEEECCCCC
QIRFAQADVRGTWKSAFPSRPGDLLNLRDLEQGLEQMKRVASQDVDMQLVPTDVPGVSDV
CEEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEE
VISVKRTKPWTVVAAVDNSGTRSTGKLQGNLSLSLDNPLGLSDLFNVGYSQDLDFSNKER
EEEEECCCCEEEEEEECCCCCCCCCEEEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCC
GTHGWNGFYSVPWGYWTATVSAYSSTYFQQIAGVNQTFVSSGNSQNFDVKLQRVIERSQN
CCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHCCCC
DVLGVQFRLSKRFGKNFVDDTEIPQQRRNNTVAEAGLTDRHYFGAAQFDGSLLLRHGVGD
CEEEEEEEEHHHHCCCCCCCCCCCHHHCCCCCHHCCCCCCCEECEECCCCCEEEECCCCC
FGAQDDTLADGGGPTWHYRMLVADANLSVPFKVGTQPLRYVTTFRGQFTNDHLYSIDAIT
CCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEECCCHHHHHHHHCCCCCCCCEEEEEEEE
IGSRYTVRGFDGEMSLLGDRGFYWRNELQAPIGNTGLSLYGGLDYGHVYGPSTVGLAGTQ
ECCEEEEEECCCCEEEECCCCCEEHHHCCCCCCCCCEEEECCCCCCCEECCCCCCCCHHH
LAGAVIGLRGGWGTSYGSLSYDLFIGTPVYKPAAFNTARITTGFQLVYQY
HHCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEECCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2407716 [H]