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The map label for this gene is dapB [H]

Identifier: 17230034

GI number: 17230034

Start: 3046252

End: 3047088

Strand: Direct

Name: dapB [H]

Synonym: alr2542

Alternate gene names: 17230034

Gene position: 3046252-3047088 (Clockwise)

Preceding gene: 17230033

Following gene: 17230035

Centisome position: 47.5

GC content: 44.56

Gene sequence:

>837_bases
ATGACAAATCAAGCTCCTATCCCAGTTATTGTCAATGGTGCTGCTGGCAAAATGGGACGTGAAGTAGTCAAAGCAGTAGC
CCAAGCACCAGACTTAAACTTATTGGGTGCAATTGACAGCAGTCCAGAACATCAAGGTAAAGATGCAGGAGAATTAGCGG
GGTTAAGTGAACCTCTGGAAGTTCCCATCACAAACCAACTAGAACCAATGCTGGGTTATGTCGCTGGAGAAAGACAGGGG
CCGCCAGGGGTAATAGTAGACTTTACTCATCCTGACTCAGTTTATGATAATGTACGCAGTGCGATCGCCTACGGTATTCG
TCCGGTTGTTGGTACGACAGGATTAAGCCCAGCACAAATCCAAAATTTAGCTGATTTTGCCGAAAAAGCCAGCACTGGCT
GTCTGATTATTCCTAACTTCTCCATAGGTATGGTGTTGCTACAACAAGCAGCCGTCACCGCATCACAATATTTTGACCAC
GTAGAAATCATCGAACTGCACCACAATCAAAAAGCCGATGCACCCAGTGGTACAGCTATTCAAACCGCCGAGTTACTAGC
AGAATTGGGTAAAACTTTTAACTCTGCTATTGTGGAAGAGACGGAAAAAATACCCGGAGCTAGAGGTAGTTTAGCTGAGG
AAGGAATTAGAATTCATAGCGTCCGCTTACCCGGACTGATAGCCCATCAAGAAGTAATTTTTGGCGCACCAGGACAAATT
TATACATTACGCCATGATACAAGCGATCGCGCCTGCTATATGCCTGGAGTTTTACTTGCGATTCGCAAAGTCTTACAGCT
AAAGTCGTTAGTATATGGTTTAGAAAAGATCCTTTAA

Upstream 100 bases:

>100_bases
GAAAAAAGCCTACTTGGGTTGATTATATTGCTGAGATCATTTACGTGGGAAAACTGATAATATCTGTGGGGATTGGTAAT
CGGTAAAATCAGGAAGAGTT

Downstream 100 bases:

>100_bases
ACTTCAAACTCCCCATTCCCCACTCATGTTAGTTCCACTGACTCGCCAGAAATTTGAACAACTAATTCCTTTAATTGCCA
CTGGCCCGCAGTATAAGTAC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MTNQAPIPVIVNGAAGKMGREVVKAVAQAPDLNLLGAIDSSPEHQGKDAGELAGLSEPLEVPITNQLEPMLGYVAGERQG
PPGVIVDFTHPDSVYDNVRSAIAYGIRPVVGTTGLSPAQIQNLADFAEKASTGCLIIPNFSIGMVLLQQAAVTASQYFDH
VEIIELHHNQKADAPSGTAIQTAELLAELGKTFNSAIVEETEKIPGARGSLAEEGIRIHSVRLPGLIAHQEVIFGAPGQI
YTLRHDTSDRACYMPGVLLAIRKVLQLKSLVYGLEKIL

Sequences:

>Translated_278_residues
MTNQAPIPVIVNGAAGKMGREVVKAVAQAPDLNLLGAIDSSPEHQGKDAGELAGLSEPLEVPITNQLEPMLGYVAGERQG
PPGVIVDFTHPDSVYDNVRSAIAYGIRPVVGTTGLSPAQIQNLADFAEKASTGCLIIPNFSIGMVLLQQAAVTASQYFDH
VEIIELHHNQKADAPSGTAIQTAELLAELGKTFNSAIVEETEKIPGARGSLAEEGIRIHSVRLPGLIAHQEVIFGAPGQI
YTLRHDTSDRACYMPGVLLAIRKVLQLKSLVYGLEKIL
>Mature_277_residues
TNQAPIPVIVNGAAGKMGREVVKAVAQAPDLNLLGAIDSSPEHQGKDAGELAGLSEPLEVPITNQLEPMLGYVAGERQGP
PGVIVDFTHPDSVYDNVRSAIAYGIRPVVGTTGLSPAQIQNLADFAEKASTGCLIIPNFSIGMVLLQQAAVTASQYFDHV
EIIELHHNQKADAPSGTAIQTAELLAELGKTFNSAIVEETEKIPGARGSLAEEGIRIHSVRLPGLIAHQEVIFGAPGQIY
TLRHDTSDRACYMPGVLLAIRKVLQLKSLVYGLEKIL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=283, Percent_Identity=29.3286219081272, Blast_Score=95, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 29522; Mature: 29391

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNQAPIPVIVNGAAGKMGREVVKAVAQAPDLNLLGAIDSSPEHQGKDAGELAGLSEPLE
CCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHCCCCCCCC
VPITNQLEPMLGYVAGERQGPPGVIVDFTHPDSVYDNVRSAIAYGIRPVVGTTGLSPAQI
CCCCCCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCHHHHCCCCCCHHHH
QNLADFAEKASTGCLIIPNFSIGMVLLQQAAVTASQYFDHVEIIELHHNQKADAPSGTAI
HHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHH
QTAELLAELGKTFNSAIVEETEKIPGARGSLAEEGIRIHSVRLPGLIAHQEVIFGAPGQI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEEEEECCCEEEHHHHEECCCCCE
YTLRHDTSDRACYMPGVLLAIRKVLQLKSLVYGLEKIL
EEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TNQAPIPVIVNGAAGKMGREVVKAVAQAPDLNLLGAIDSSPEHQGKDAGELAGLSEPLE
CCCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHCCCCCCCC
VPITNQLEPMLGYVAGERQGPPGVIVDFTHPDSVYDNVRSAIAYGIRPVVGTTGLSPAQI
CCCCCCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCHHHHCCCCCCHHHH
QNLADFAEKASTGCLIIPNFSIGMVLLQQAAVTASQYFDHVEIIELHHNQKADAPSGTAI
HHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHH
QTAELLAELGKTFNSAIVEETEKIPGARGSLAEEGIRIHSVRLPGLIAHQEVIFGAPGQI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEEEEECCCEEEHHHHEECCCCCE
YTLRHDTSDRACYMPGVLLAIRKVLQLKSLVYGLEKIL
EEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA