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The map label for this gene is alr [H]

Identifier: 17229950

GI number: 17229950

Start: 2953896

End: 2955101

Strand: Direct

Name: alr [H]

Synonym: alr2458

Alternate gene names: 17229950

Gene position: 2953896-2955101 (Clockwise)

Preceding gene: 17229946

Following gene: 17229954

Centisome position: 46.06

GC content: 45.61

Gene sequence:

>1206_bases
GTGATAAGGGGGAGTGAAATGTTAAGTCGCCAACAAGCCTCAAGTATGGCTTCTCATCAACAATGTGATACCTATGCTTG
GTTTTCACAACGCGCTTGGGTAGAAATTGACCTAGAGGCGTTGTCGCACAATGTCCAGCAACTTAAGCAGTTTTTATCAC
CGCGTACTCAGTTAATGGCAGTAGTTAAAGCAGATGCTTATGGTCATGGTGCTGTGACGGTGGCACAGACAGCATTACAA
GCGGGGGCTAGTTGTTTGGGTGTCGCCACTGTTCCAGAGGGTATTCAATTGCGAGAGGCCGGTATTCAAGCGCCCATTTT
GATTTTAGGGGCTACCCATACACCAGAACAAATTCAGGCGATCGCTCAATGGCAACTCCAAGCAACTATTGGTAGTCCCA
AACAAGCTTTAATATTTTCCAATACCTTGGAAACCATCCAGCATGATTCTCCTATACCTGTACATATTAAGTTAGATACG
GGTATGTCTAGACTGGGTACTAACTGGCAACAAGCAGGGGAGTTTGTACAGTTAGTAGAGCGTTTACCCCATTTGGATAT
TGCTAGTGTTTACTCCCACCTAGCGACCGCAGATAGCCCAGATCCAGGGATTATGGAAGAACAGCATAGAAGATTTGAGG
AGGCGATCGCTCAAATCAAAACTTTGGGTATTAAAATTCCTAGCCTGCATTTAGCAAACTCGGCTGCAACCCTGGCAGAT
CCGAGATTACACTATGATATGGTACGGGTAGGTTTAGCCGTGTATGGACTCTATCCAGCCCCTCATTTACAGAATAAAAT
CAGCCTAAAACCAGTCATCCAAGTCCAAGCGCGAATTACCCACGTCAAAACAATTGCTGCCGGTACTGGCGTAAGCTACG
GACACCAATTTATAGCCCCTCATGAAATGCGCCTTGCCGTTGTGAGTATTGGTTACGCTGATGGCGTACCGCGTAATCTA
TCCAACAAAATGCAGGTTTTAATTCGTGGTCAACGAGTGCCACAAATCGGTGCTATCACGATGGATCAGTTGATGATAGA
TGCTAGTGCTTTACCAGACCTACAAGAAGGGGAAATTGTCACCTTACTTGGGAAACAAGGAAAGGAAAAAATCACAGCCG
ATGATTGGGCAGAAGCGTTAAACACTATTTCCTGGGAAGTTCTTTGTGGATTTAAACATCGCCTACCTCGTGTAGGCGTG
ATGTGA

Upstream 100 bases:

>100_bases
TGATTAACTCTGATGTGGCTATAAAACCAATTCGCAATAGCCTGCGGCAAGGCTAACGCCAACGCAATTCGGAATAAATA
CGCATTTAAAAAGCAGTGGT

Downstream 100 bases:

>100_bases
TTGTTACGAATTTTTAACTAATACCTATTATCTATTGCCTATTCCCTGAGATAAAGTGCTATACTAGTATAGTTGCATAA
GCGGATGTGGCGGAATTGGC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MIRGSEMLSRQQASSMASHQQCDTYAWFSQRAWVEIDLEALSHNVQQLKQFLSPRTQLMAVVKADAYGHGAVTVAQTALQ
AGASCLGVATVPEGIQLREAGIQAPILILGATHTPEQIQAIAQWQLQATIGSPKQALIFSNTLETIQHDSPIPVHIKLDT
GMSRLGTNWQQAGEFVQLVERLPHLDIASVYSHLATADSPDPGIMEEQHRRFEEAIAQIKTLGIKIPSLHLANSAATLAD
PRLHYDMVRVGLAVYGLYPAPHLQNKISLKPVIQVQARITHVKTIAAGTGVSYGHQFIAPHEMRLAVVSIGYADGVPRNL
SNKMQVLIRGQRVPQIGAITMDQLMIDASALPDLQEGEIVTLLGKQGKEKITADDWAEALNTISWEVLCGFKHRLPRVGV
M

Sequences:

>Translated_401_residues
MIRGSEMLSRQQASSMASHQQCDTYAWFSQRAWVEIDLEALSHNVQQLKQFLSPRTQLMAVVKADAYGHGAVTVAQTALQ
AGASCLGVATVPEGIQLREAGIQAPILILGATHTPEQIQAIAQWQLQATIGSPKQALIFSNTLETIQHDSPIPVHIKLDT
GMSRLGTNWQQAGEFVQLVERLPHLDIASVYSHLATADSPDPGIMEEQHRRFEEAIAQIKTLGIKIPSLHLANSAATLAD
PRLHYDMVRVGLAVYGLYPAPHLQNKISLKPVIQVQARITHVKTIAAGTGVSYGHQFIAPHEMRLAVVSIGYADGVPRNL
SNKMQVLIRGQRVPQIGAITMDQLMIDASALPDLQEGEIVTLLGKQGKEKITADDWAEALNTISWEVLCGFKHRLPRVGV
M
>Mature_401_residues
MIRGSEMLSRQQASSMASHQQCDTYAWFSQRAWVEIDLEALSHNVQQLKQFLSPRTQLMAVVKADAYGHGAVTVAQTALQ
AGASCLGVATVPEGIQLREAGIQAPILILGATHTPEQIQAIAQWQLQATIGSPKQALIFSNTLETIQHDSPIPVHIKLDT
GMSRLGTNWQQAGEFVQLVERLPHLDIASVYSHLATADSPDPGIMEEQHRRFEEAIAQIKTLGIKIPSLHLANSAATLAD
PRLHYDMVRVGLAVYGLYPAPHLQNKISLKPVIQVQARITHVKTIAAGTGVSYGHQFIAPHEMRLAVVSIGYADGVPRNL
SNKMQVLIRGQRVPQIGAITMDQLMIDASALPDLQEGEIVTLLGKQGKEKITADDWAEALNTISWEVLCGFKHRLPRVGV
M

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=369, Percent_Identity=31.4363143631436, Blast_Score=167, Evalue=8e-43,
Organism=Escherichia coli, GI1790487, Length=373, Percent_Identity=31.3672922252011, Blast_Score=167, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 43823; Mature: 43823

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRGSEMLSRQQASSMASHQQCDTYAWFSQRAWVEIDLEALSHNVQQLKQFLSPRTQLMA
CCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCHHHHHH
VVKADAYGHGAVTVAQTALQAGASCLGVATVPEGIQLREAGIQAPILILGATHTPEQIQA
HHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEHHCCCCCCEEEEECCCCHHHHHH
IAQWQLQATIGSPKQALIFSNTLETIQHDSPIPVHIKLDTGMSRLGTNWQQAGEFVQLVE
HHHHHEEEECCCCCEEEEEHHHHHHHHCCCCCEEEEEECCCHHHHCCCHHHHHHHHHHHH
RLPHLDIASVYSHLATADSPDPGIMEEQHRRFEEAIAQIKTLGIKIPSLHLANSAATLAD
HCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCEECCCEEECCCCHHHCC
PRLHYDMVRVGLAVYGLYPAPHLQNKISLKPVIQVQARITHVKTIAAGTGVSYGHQFIAP
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
HEMRLAVVSIGYADGVPRNLSNKMQVLIRGQRVPQIGAITMDQLMIDASALPDLQEGEIV
CCEEEEEEEEECCCCCCCCHHHHHHHHEECCCCCCCCCEEHHHHHHHHHHCCCCCCCCEE
TLLGKQGKEKITADDWAEALNTISWEVLCGFKHRLPRVGVM
EEECCCCCCCCCHHHHHHHHHHCCHHEEECHHHCCCCCCCC
>Mature Secondary Structure
MIRGSEMLSRQQASSMASHQQCDTYAWFSQRAWVEIDLEALSHNVQQLKQFLSPRTQLMA
CCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCHHHHHH
VVKADAYGHGAVTVAQTALQAGASCLGVATVPEGIQLREAGIQAPILILGATHTPEQIQA
HHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEHHCCCCCCEEEEECCCCHHHHHH
IAQWQLQATIGSPKQALIFSNTLETIQHDSPIPVHIKLDTGMSRLGTNWQQAGEFVQLVE
HHHHHEEEECCCCCEEEEEHHHHHHHHCCCCCEEEEEECCCHHHHCCCHHHHHHHHHHHH
RLPHLDIASVYSHLATADSPDPGIMEEQHRRFEEAIAQIKTLGIKIPSLHLANSAATLAD
HCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCEECCCEEECCCCHHHCC
PRLHYDMVRVGLAVYGLYPAPHLQNKISLKPVIQVQARITHVKTIAAGTGVSYGHQFIAP
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
HEMRLAVVSIGYADGVPRNLSNKMQVLIRGQRVPQIGAITMDQLMIDASALPDLQEGEIV
CCEEEEEEEEECCCCCCCCHHHHHHHHEECCCCCCCCCEEHHHHHHHHHHCCCCCCCCEE
TLLGKQGKEKITADDWAEALNTISWEVLCGFKHRLPRVGVM
EEECCCCCCCCCHHHHHHHHHHCCHHEEECHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]