Click here to switch to the map view.

The map label for this gene is prcA [H]

Identifier: 17228876

GI number: 17228876

Start: 1636028

End: 1638016

Strand: Direct

Name: prcA [H]

Synonym: alr1381

Alternate gene names: 17228876

Gene position: 1636028-1638016 (Clockwise)

Preceding gene: 17228874

Following gene: 17228877

Centisome position: 25.51

GC content: 47.71

Gene sequence:

>1989_bases
ATGGTTCATGTCCGCTATGGTGGTCAGAACGGTGAACAGTACGAACTAGCAATTAGTGAAAATCATATTGTAGTGCGGAC
TGAAAGCCGCAGCTCGCTAATTAGCGATCGCCCCTTTGAAGCCGCCCCTGTTTCCTCCCAAGCCCGTAATATCCTCAATC
AGTTCGAGTTATCCACTCGTTTCAGCCAAGCGGGTGTAGAAGTTCTCCATGTGAAAGAACCGAGCCAGGATGGTGCTTTG
CGCGATACAGCCAGGGAAATTCTCAATCAAGAACCGGAAGTGCAATTTGCTGGACGTGTGTTAATTGATCCAGTCAGTCA
ACAACCCATAGTTTACACAGAAAACCTTTTCGTGAAGTTTGGCCACGAAGAAGACGTTAGTTTCTGCCAAGAAATTTTGG
GACGCTACGGCTTAACAATTAAACGTCAACTAGAATACGCCCGTAATGCCTACTTTGTCAGCGCACCCCCCAATACTGGT
TTAGCCATCTTTGATATTGCCGAAAGGTTGCTCAACGAGGAATCGGTGGAATTGTGTCATCCTGAATTGGTGCGGGAATT
TAGGCAACGTCAGGCATTTTCCCAACAATGGCACCTTAAGGAAACCACAATTGGGGGTAAGACTATCAAGGCTCATGCCA
ATGTTGAGGCGGCATGGAAGTTGAGCGATGGTACGGGAACGATTATTGCCATTATTGACGATGGTGTGGATGTTGACCAT
GAAGAATTCCGTTCTTCTGGTAAGATTGTTGCCCCTAGAGATGTCACACGCAAAACTAACTTTCCCACCCCAGGAAACCG
AGATAATCACGGTACTGCTTGTGCAGGTGTCGCTTGTGGTAATGGCAACTTTGGGGCTTCTGGTGTAGCGCCTGGGGCTA
AGTTAATGCCCATTCGTTTCGTTTCCGCCCTGGGTTCCCAAGATGAAGCCGACTCTTTTGTCTGGGCTGCTCAAAATGGT
GCGGATGTAATTTCCTGTAGTTGGGGGCCACCAGATGGTACATGGTGGGATGATAAAGACCCCCTACACAAGCAGAAAGT
ACCTCTACCCGATTCCACAAGACTAGCAATGGACTATGCCATCAATAAGGGGCGTAATGGCAAAGGATGTGTGATTTTAT
TCGCTGCGGGTAATGGTAACGAAAGCGTAGATAATGACGGCTACGCCAGCTATGAAAAGGTAATAGCTGTCGCGGCTTGT
AACGACTTTGGTACTAGAAGCGCTTATAGTGATTTTGGTCAAGCCGTCTGGTGTGCCTTCCCTAGTAACAACGGTAACCC
TTCCCAAACCCCTGGTATTTGGACTGCCGATCGCTCTGGTGTAGTTGGCTATAATTCTGGTAGTACCAATCTCGGTGATC
AAGCAGGTAATTATACAAATAGTTTCGGTGGTACTTCTAGCGCCTGTCCGGGTGCGGCTGGTGTCGCTGCCTTGATTCTC
TCCCGCAATCCAAATCTGCGTTGGGATGAGGTCAGAGATATTATTAAACGTTCATGCGATCGCATTGATCCAGTCGGTGG
TAACTATAACGCTGAAGGCCGTAGCCCATTCTACGGTTATGGTCGGATCAATGCCCTCAAAGCGGTAGAATTGGCACTAC
CAGCACAACCTGAGCCAGTCAGCATTTTTACAGCCGTCCAGGATGTCCCCATTAATGATTTGCAGACATCTCAACTCAGT
TTAGCGATCGCCAACACCAACCCCATCAAATCTATCAAAGTTACAGTAGACATCGAGCATACTTACATTGGTGACTTAAT
AGTTAGCCTCAACCCCCCTGGAGAATGTGGTGTATTACCGATCATCCTCCACGACCGCAAAGGTGGAGGCGCAGATGATA
TCAAACAAACTTACGATGAGGTGAGTACACCAGGACTGACTGCTTTGAAGGGTAAAATTCCTCAAGGAACCTGGACTCTA
GAAGTAGCAGATAAAGCACAGGCGGATACAGGGAAGATTCGCAGCTTGACTATTGAACTTGGGTTTTAG

Upstream 100 bases:

>100_bases
ACAGGAAATTATTCTCAGCTGCGTCTTATGTGTGCATCATTTTGGAAACCACACACAAAATACAAAGGCTTAGTATCAAC
TTAATAGTAGGAGATTAAGT

Downstream 100 bases:

>100_bases
GGGGATTGGGGACTGGGGATTGGGGACTGGGGATTGGGGACTGGGTAAAACTTTTACTGTTCTCTGCTCCTCTACCTCTT
AAGATTCCCCAGTTTCTCTG

Product: trypsin

Products: NA

Alternate protein names: Trypsin [H]

Number of amino acids: Translated: 662; Mature: 662

Protein sequence:

>662_residues
MVHVRYGGQNGEQYELAISENHIVVRTESRSSLISDRPFEAAPVSSQARNILNQFELSTRFSQAGVEVLHVKEPSQDGAL
RDTAREILNQEPEVQFAGRVLIDPVSQQPIVYTENLFVKFGHEEDVSFCQEILGRYGLTIKRQLEYARNAYFVSAPPNTG
LAIFDIAERLLNEESVELCHPELVREFRQRQAFSQQWHLKETTIGGKTIKAHANVEAAWKLSDGTGTIIAIIDDGVDVDH
EEFRSSGKIVAPRDVTRKTNFPTPGNRDNHGTACAGVACGNGNFGASGVAPGAKLMPIRFVSALGSQDEADSFVWAAQNG
ADVISCSWGPPDGTWWDDKDPLHKQKVPLPDSTRLAMDYAINKGRNGKGCVILFAAGNGNESVDNDGYASYEKVIAVAAC
NDFGTRSAYSDFGQAVWCAFPSNNGNPSQTPGIWTADRSGVVGYNSGSTNLGDQAGNYTNSFGGTSSACPGAAGVAALIL
SRNPNLRWDEVRDIIKRSCDRIDPVGGNYNAEGRSPFYGYGRINALKAVELALPAQPEPVSIFTAVQDVPINDLQTSQLS
LAIANTNPIKSIKVTVDIEHTYIGDLIVSLNPPGECGVLPIILHDRKGGGADDIKQTYDEVSTPGLTALKGKIPQGTWTL
EVADKAQADTGKIRSLTIELGF

Sequences:

>Translated_662_residues
MVHVRYGGQNGEQYELAISENHIVVRTESRSSLISDRPFEAAPVSSQARNILNQFELSTRFSQAGVEVLHVKEPSQDGAL
RDTAREILNQEPEVQFAGRVLIDPVSQQPIVYTENLFVKFGHEEDVSFCQEILGRYGLTIKRQLEYARNAYFVSAPPNTG
LAIFDIAERLLNEESVELCHPELVREFRQRQAFSQQWHLKETTIGGKTIKAHANVEAAWKLSDGTGTIIAIIDDGVDVDH
EEFRSSGKIVAPRDVTRKTNFPTPGNRDNHGTACAGVACGNGNFGASGVAPGAKLMPIRFVSALGSQDEADSFVWAAQNG
ADVISCSWGPPDGTWWDDKDPLHKQKVPLPDSTRLAMDYAINKGRNGKGCVILFAAGNGNESVDNDGYASYEKVIAVAAC
NDFGTRSAYSDFGQAVWCAFPSNNGNPSQTPGIWTADRSGVVGYNSGSTNLGDQAGNYTNSFGGTSSACPGAAGVAALIL
SRNPNLRWDEVRDIIKRSCDRIDPVGGNYNAEGRSPFYGYGRINALKAVELALPAQPEPVSIFTAVQDVPINDLQTSQLS
LAIANTNPIKSIKVTVDIEHTYIGDLIVSLNPPGECGVLPIILHDRKGGGADDIKQTYDEVSTPGLTALKGKIPQGTWTL
EVADKAQADTGKIRSLTIELGF
>Mature_662_residues
MVHVRYGGQNGEQYELAISENHIVVRTESRSSLISDRPFEAAPVSSQARNILNQFELSTRFSQAGVEVLHVKEPSQDGAL
RDTAREILNQEPEVQFAGRVLIDPVSQQPIVYTENLFVKFGHEEDVSFCQEILGRYGLTIKRQLEYARNAYFVSAPPNTG
LAIFDIAERLLNEESVELCHPELVREFRQRQAFSQQWHLKETTIGGKTIKAHANVEAAWKLSDGTGTIIAIIDDGVDVDH
EEFRSSGKIVAPRDVTRKTNFPTPGNRDNHGTACAGVACGNGNFGASGVAPGAKLMPIRFVSALGSQDEADSFVWAAQNG
ADVISCSWGPPDGTWWDDKDPLHKQKVPLPDSTRLAMDYAINKGRNGKGCVILFAAGNGNESVDNDGYASYEKVIAVAAC
NDFGTRSAYSDFGQAVWCAFPSNNGNPSQTPGIWTADRSGVVGYNSGSTNLGDQAGNYTNSFGGTSSACPGAAGVAALIL
SRNPNLRWDEVRDIIKRSCDRIDPVGGNYNAEGRSPFYGYGRINALKAVELALPAQPEPVSIFTAVQDVPINDLQTSQLS
LAIANTNPIKSIKVTVDIEHTYIGDLIVSLNPPGECGVLPIILHDRKGGGADDIKQTYDEVSTPGLTALKGKIPQGTWTL
EVADKAQADTGKIRSLTIELGF

Specific function: Degrades phycobiliproteins in vitro. Has a substrate specificity similar to that of trypsin [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI295424143, Length=533, Percent_Identity=25.140712945591, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI20336244, Length=563, Percent_Identity=27.708703374778, Blast_Score=127, Evalue=5e-29,
Organism=Homo sapiens, GI20336242, Length=532, Percent_Identity=25.187969924812, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI4505579, Length=534, Percent_Identity=24.5318352059925, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI27894285, Length=489, Percent_Identity=26.7893660531697, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI20336190, Length=489, Percent_Identity=26.7893660531697, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI20336188, Length=488, Percent_Identity=26.2295081967213, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI20336182, Length=488, Percent_Identity=25.8196721311475, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI4505577, Length=488, Percent_Identity=25.8196721311475, Blast_Score=106, Evalue=7e-23,
Organism=Homo sapiens, GI20336184, Length=488, Percent_Identity=25.8196721311475, Blast_Score=106, Evalue=7e-23,
Organism=Homo sapiens, GI20336180, Length=488, Percent_Identity=25.8196721311475, Blast_Score=106, Evalue=8e-23,
Organism=Homo sapiens, GI76443679, Length=494, Percent_Identity=26.9230769230769, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI20336246, Length=465, Percent_Identity=26.8817204301075, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI299523015, Length=470, Percent_Identity=26.3829787234043, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI20336248, Length=364, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI20336186, Length=369, Percent_Identity=28.1842818428184, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI71987206, Length=505, Percent_Identity=26.3366336633663, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71983555, Length=339, Percent_Identity=29.4985250737463, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71988301, Length=513, Percent_Identity=26.9005847953216, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71988315, Length=513, Percent_Identity=26.9005847953216, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71988321, Length=513, Percent_Identity=26.9005847953216, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71988297, Length=513, Percent_Identity=26.9005847953216, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI25141268, Length=355, Percent_Identity=28.7323943661972, Blast_Score=109, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI71988308, Length=512, Percent_Identity=26.5625, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI71988312, Length=512, Percent_Identity=26.5625, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17505240, Length=315, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71987215, Length=446, Percent_Identity=25.3363228699552, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324091, Length=436, Percent_Identity=31.8807339449541, Blast_Score=146, Evalue=1e-35,
Organism=Drosophila melanogaster, GI17136192, Length=607, Percent_Identity=25.8649093904448, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24642494, Length=480, Percent_Identity=27.5, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24642490, Length=480, Percent_Identity=27.5, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI45555723, Length=480, Percent_Identity=27.5, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24642492, Length=480, Percent_Identity=27.5, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281360987, Length=480, Percent_Identity=27.5, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24642488, Length=480, Percent_Identity=27.5, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24642484, Length=480, Percent_Identity=27.5, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24642486, Length=480, Percent_Identity=27.5, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI17864552, Length=481, Percent_Identity=27.8586278586279, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45553515, Length=480, Percent_Identity=26.4583333333333, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24650058, Length=480, Percent_Identity=26.4583333333333, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24650060, Length=480, Percent_Identity=26.4583333333333, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45553513, Length=480, Percent_Identity=26.4583333333333, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24650056, Length=479, Percent_Identity=27.7661795407098, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281360985, Length=249, Percent_Identity=30.1204819277108, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR002884 [H]

Pfam domain/function: PF01483 P_proprotein; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 71527; Mature: 71527

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHVRYGGQNGEQYELAISENHIVVRTESRSSLISDRPFEAAPVSSQARNILNQFELSTR
CEEEEECCCCCCEEEEEEECCEEEEEECCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
FSQAGVEVLHVKEPSQDGALRDTAREILNQEPEVQFAGRVLIDPVSQQPIVYTENLFVKF
HHHCCEEEEEEECCCCCCCHHHHHHHHHCCCCCEEECCEEEECCCCCCCEEEECCEEEEE
GHEEDVSFCQEILGRYGLTIKRQLEYARNAYFVSAPPNTGLAIFDIAERLLNEESVELCH
CCCCHHHHHHHHHHHHCCEEEEHHHHHCCEEEEECCCCCCEEHHHHHHHHHCCCCHHHCC
PELVREFRQRQAFSQQWHLKETTIGGKTIKAHANVEAAWKLSDGTGTIIAIIDDGVDVDH
HHHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCEEEEEEEECCCCEEEEEEECCCCCCH
EEFRSSGKIVAPRDVTRKTNFPTPGNRDNHGTACAGVACGNGNFGASGVAPGAKLMPIRF
HHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEHHHHH
VSALGSQDEADSFVWAAQNGADVISCSWGPPDGTWWDDKDPLHKQKVPLPDSTRLAMDYA
HHHHCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEH
INKGRNGKGCVILFAAGNGNESVDNDGYASYEKVIAVAACNDFGTRSAYSDFGQAVWCAF
HCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHEEEEEECCCCCCCHHHHHCCCEEEEEE
PSNNGNPSQTPGIWTADRSGVVGYNSGSTNLGDQAGNYTNSFGGTSSACPGAAGVAALIL
CCCCCCCCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEEEE
SRNPNLRWDEVRDIIKRSCDRIDPVGGNYNAEGRSPFYGYGRINALKAVELALPAQPEPV
ECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCEEEEEEECCCCCCCE
SIFTAVQDVPINDLQTSQLSLAIANTNPIKSIKVTVDIEHTYIGDLIVSLNPPGECGVLP
EEEEEEECCCCCCCCCCEEEEEEECCCCCEEEEEEEEEEEEEEEEEEEEECCCCCCCEEE
IILHDRKGGGADDIKQTYDEVSTPGLTALKGKIPQGTWTLEVADKAQADTGKIRSLTIEL
EEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEECCCCCCCCCCEEEEEEEE
GF
CC
>Mature Secondary Structure
MVHVRYGGQNGEQYELAISENHIVVRTESRSSLISDRPFEAAPVSSQARNILNQFELSTR
CEEEEECCCCCCEEEEEEECCEEEEEECCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
FSQAGVEVLHVKEPSQDGALRDTAREILNQEPEVQFAGRVLIDPVSQQPIVYTENLFVKF
HHHCCEEEEEEECCCCCCCHHHHHHHHHCCCCCEEECCEEEECCCCCCCEEEECCEEEEE
GHEEDVSFCQEILGRYGLTIKRQLEYARNAYFVSAPPNTGLAIFDIAERLLNEESVELCH
CCCCHHHHHHHHHHHHCCEEEEHHHHHCCEEEEECCCCCCEEHHHHHHHHHCCCCHHHCC
PELVREFRQRQAFSQQWHLKETTIGGKTIKAHANVEAAWKLSDGTGTIIAIIDDGVDVDH
HHHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCEEEEEEEECCCCEEEEEEECCCCCCH
EEFRSSGKIVAPRDVTRKTNFPTPGNRDNHGTACAGVACGNGNFGASGVAPGAKLMPIRF
HHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEHHHHH
VSALGSQDEADSFVWAAQNGADVISCSWGPPDGTWWDDKDPLHKQKVPLPDSTRLAMDYA
HHHHCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEH
INKGRNGKGCVILFAAGNGNESVDNDGYASYEKVIAVAACNDFGTRSAYSDFGQAVWCAF
HCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHEEEEEECCCCCCCHHHHHCCCEEEEEE
PSNNGNPSQTPGIWTADRSGVVGYNSGSTNLGDQAGNYTNSFGGTSSACPGAAGVAALIL
CCCCCCCCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEEEE
SRNPNLRWDEVRDIIKRSCDRIDPVGGNYNAEGRSPFYGYGRINALKAVELALPAQPEPV
ECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCEEEEEEECCCCCCCE
SIFTAVQDVPINDLQTSQLSLAIANTNPIKSIKVTVDIEHTYIGDLIVSLNPPGECGVLP
EEEEEEECCCCCCCCCCEEEEEEECCCCCEEEEEEEEEEEEEEEEEEEEECCCCCCCEEE
IILHDRKGGGADDIKQTYDEVSTPGLTALKGKIPQGTWTLEVADKAQADTGKIRSLTIEL
EEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEECCCCCCCCCCEEEEEEEE
GF
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1900347; 8944762 [H]