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The map label for this gene is apxIIID [H]

Identifier: 17228695

GI number: 17228695

Start: 1413295

End: 1415427

Strand: Direct

Name: apxIIID [H]

Synonym: alr1200

Alternate gene names: 17228695

Gene position: 1413295-1415427 (Clockwise)

Preceding gene: 17228694

Following gene: 17228696

Centisome position: 22.04

GC content: 46.65

Gene sequence:

>2133_bases
GTGAACACCTTACGCCGCCAAGAGAATGATTTTTGGCATCGATCGCATCAGCCAATTCCCGAAGAACTTCCTACCTTGGA
AGCTAACGAATTTTTACCCCATATTGGGAAATGGACAAGTATCGGTGGGGTAGTTGTCTTCAGTATCTTTATTGTGGGGG
TGGTGCTAACATCTGTTCTCAAGTACAACGTGACGGTGAAAGTGCCGGCGACTATTCGCCCTGTGGGAGAATTAAGGCTG
GTACAGTCGCTAATTAATGGCAAAATTCTCAAGATTAGTGTTGCAGAAAATCAGATGGTAGCCGAAGGACAAGCGATCGC
CTACATTGATGATTCCCGCCTCCAGACTCAAAAGAGCCAGTTACAAAACCTCATCCAGCAAAGTCAACTACAACTCAATA
AAATCGATGCACAGTTGGGAGAAATCGACGCTCAAATTACAGCACAGACAAATTTAAACGATCGCACCACAATCGCTGCA
CAAGCTGAACTGAGTGGTACACAACGCAACTATGCCGATCAGCAAGTGAAAGCTACGGCGGATATGACACAAGCACAATC
AGCCTTAACTTTAGCCAGGATCCAAAAAGACCGCCTGCAACGGGAAAAGCTGTTAACGGCGACTGTGCGAGAAACAGAAG
CCGCTTTGCAGTTAGCCAGGGTGCAAAGCGATCGCCTACAACGGGAAAAGCTGCTAAAAACTACCGTAGATGAAGCGGAA
AGAGGCTTAAAATTGGCGAGAGAACAACGCGATCGTTTACGACGGGATAGGCTTCTCAGGACGACTGTGCAAGAAACACA
GACGGCTTTGAACTTAGCAAAGGCGCAACAAGAAAGATTACAAAGGGAACAACTCTTAGCCAAAACTGTGCAGGAAGCAG
AAACCGCTTTAAATTTAGCCAGGGTACAACGCGATCGCCTACAACAAGATAGAGTTTTAACTGCAACTGTCCAAGAAGCA
GAAGCCGCCTTGAGTTTAGCTAGAGTACAGCGAGAAAGATTACAGCCGATAGTAGCATCAGGAGCGATCGCCCGTAGTTT
CTTCGAGGAAAAAGACCAAGCCGTAATATCGGCGGAGGCGAGGCTGGAACAAGCCAAAGCTAACGCTAAAAATCTGCTGG
AAGAGAAAGAACAAGCGGTGATTGCGGCGGAGGCGAAGTTGGAACAAGCCAAAGCCAACGCCAAAAATCTTTTGGAGGAG
AAAGAACAGGCTGTCAAATCAGCAGAAGCGAAGCTAGAACAAGCCAAAGCCAACGCTAAAAATCTCTTAGAAGAAAAAGA
CCAAGGGGTGATTGCGGCGGAGGCGAAACTGGAACAAGCCAAAGCCAACGCCAAAAATCTCTTAGAAGAGAAAGAACAAG
AGGTGATTGCGGCGGAGGCGAAACTGGAACAAGCCAAAGCTAACGCCAAAAATCTCCAAGAAGAAAAAGACCAAGCTTTA
ACAGTGGCGCAAACAAATCTCGCCAAGGCCAGAACAGCGATAAATCCCAATGATGCTAACGTGACTGTAGCATCGGAACG
AATTAAACAAGAACAAGCCAGGGGTGAAGTTACCTTAGCCGCCTTGAAAAAAGAAAGAGAAACTTTGCTACAACAACGCC
TAGAATTTCAAAAACAACTGGATAGAAACCGCAAAGAACTACAACAAGCCGAAAATGACTTAAAACAGAGTATAGTCCGC
GCACCCATCGCCGGGACAGTGCTGCAATTGAATTTGCGTAACCCTGGACAGGTAGTACAACCAAGTGAGGCGATCGCTCA
AATTGCGCCGTTAAATGCACCAATACAGATCAAAGCTAACGTCCAGGCGCAAGATATCAACAAAGTCAAACCCGGTCAAC
AAGTCCAAATGCAGGTTTCTGCTTGTCCCTATCCAGACTACGGCACTCTCAAAGGAACAGTCAAAACAATCGCCCCAGAT
GCCCTACCCGTAGCCAACAATAACCCACAGACCACCACAGCTAAAGCCACAGCCTATGAAGTCATTGTAGAACCACAAAC
CCCATACGTTGGTAGAGGCGATCGGCAATGTCAACTTAAAACCGGGATGCAGGGTAAAGCAGATATTATTTCCCGTCGAG
AAACAGTATTACGCTTCATCCTCCGCAAAGCCAGATTAATTGCAGATTTGTAA

Upstream 100 bases:

>100_bases
TTAACTCATCAACCCATGAATAACAGCGTCTATAAGAATAACCAAACACATCATTTAACAGCCTAATTTCTATCATATTC
ATATACCAAGGTGCAGTATC

Downstream 100 bases:

>100_bases
TTAGTTATTGGTCAATAGTCATTAGTCCATAGTCCATAGTCAATTTTCTTCCCCCTACACCCCTGCACCTAAAAAACTCC
GCGTACCTCCGCGCTAGCCT

Product: hypothetical protein

Products: NA

Alternate protein names: APX-IIID; Cytolysin IIID; CLY-IIID; Toxin RTX-III secretion protein D [H]

Number of amino acids: Translated: 710; Mature: 710

Protein sequence:

>710_residues
MNTLRRQENDFWHRSHQPIPEELPTLEANEFLPHIGKWTSIGGVVVFSIFIVGVVLTSVLKYNVTVKVPATIRPVGELRL
VQSLINGKILKISVAENQMVAEGQAIAYIDDSRLQTQKSQLQNLIQQSQLQLNKIDAQLGEIDAQITAQTNLNDRTTIAA
QAELSGTQRNYADQQVKATADMTQAQSALTLARIQKDRLQREKLLTATVRETEAALQLARVQSDRLQREKLLKTTVDEAE
RGLKLAREQRDRLRRDRLLRTTVQETQTALNLAKAQQERLQREQLLAKTVQEAETALNLARVQRDRLQQDRVLTATVQEA
EAALSLARVQRERLQPIVASGAIARSFFEEKDQAVISAEARLEQAKANAKNLLEEKEQAVIAAEAKLEQAKANAKNLLEE
KEQAVKSAEAKLEQAKANAKNLLEEKDQGVIAAEAKLEQAKANAKNLLEEKEQEVIAAEAKLEQAKANAKNLQEEKDQAL
TVAQTNLAKARTAINPNDANVTVASERIKQEQARGEVTLAALKKERETLLQQRLEFQKQLDRNRKELQQAENDLKQSIVR
APIAGTVLQLNLRNPGQVVQPSEAIAQIAPLNAPIQIKANVQAQDINKVKPGQQVQMQVSACPYPDYGTLKGTVKTIAPD
ALPVANNNPQTTTAKATAYEVIVEPQTPYVGRGDRQCQLKTGMQGKADIISRRETVLRFILRKARLIADL

Sequences:

>Translated_710_residues
MNTLRRQENDFWHRSHQPIPEELPTLEANEFLPHIGKWTSIGGVVVFSIFIVGVVLTSVLKYNVTVKVPATIRPVGELRL
VQSLINGKILKISVAENQMVAEGQAIAYIDDSRLQTQKSQLQNLIQQSQLQLNKIDAQLGEIDAQITAQTNLNDRTTIAA
QAELSGTQRNYADQQVKATADMTQAQSALTLARIQKDRLQREKLLTATVRETEAALQLARVQSDRLQREKLLKTTVDEAE
RGLKLAREQRDRLRRDRLLRTTVQETQTALNLAKAQQERLQREQLLAKTVQEAETALNLARVQRDRLQQDRVLTATVQEA
EAALSLARVQRERLQPIVASGAIARSFFEEKDQAVISAEARLEQAKANAKNLLEEKEQAVIAAEAKLEQAKANAKNLLEE
KEQAVKSAEAKLEQAKANAKNLLEEKDQGVIAAEAKLEQAKANAKNLLEEKEQEVIAAEAKLEQAKANAKNLQEEKDQAL
TVAQTNLAKARTAINPNDANVTVASERIKQEQARGEVTLAALKKERETLLQQRLEFQKQLDRNRKELQQAENDLKQSIVR
APIAGTVLQLNLRNPGQVVQPSEAIAQIAPLNAPIQIKANVQAQDINKVKPGQQVQMQVSACPYPDYGTLKGTVKTIAPD
ALPVANNNPQTTTAKATAYEVIVEPQTPYVGRGDRQCQLKTGMQGKADIISRRETVLRFILRKARLIADL
>Mature_710_residues
MNTLRRQENDFWHRSHQPIPEELPTLEANEFLPHIGKWTSIGGVVVFSIFIVGVVLTSVLKYNVTVKVPATIRPVGELRL
VQSLINGKILKISVAENQMVAEGQAIAYIDDSRLQTQKSQLQNLIQQSQLQLNKIDAQLGEIDAQITAQTNLNDRTTIAA
QAELSGTQRNYADQQVKATADMTQAQSALTLARIQKDRLQREKLLTATVRETEAALQLARVQSDRLQREKLLKTTVDEAE
RGLKLAREQRDRLRRDRLLRTTVQETQTALNLAKAQQERLQREQLLAKTVQEAETALNLARVQRDRLQQDRVLTATVQEA
EAALSLARVQRERLQPIVASGAIARSFFEEKDQAVISAEARLEQAKANAKNLLEEKEQAVIAAEAKLEQAKANAKNLLEE
KEQAVKSAEAKLEQAKANAKNLLEEKDQGVIAAEAKLEQAKANAKNLLEEKEQEVIAAEAKLEQAKANAKNLQEEKDQAL
TVAQTNLAKARTAINPNDANVTVASERIKQEQARGEVTLAALKKERETLLQQRLEFQKQLDRNRKELQQAENDLKQSIVR
APIAGTVLQLNLRNPGQVVQPSEAIAQIAPLNAPIQIKANVQAQDINKVKPGQQVQMQVSACPYPDYGTLKGTVKTIAPD
ALPVANNNPQTTTAKATAYEVIVEPQTPYVGRGDRQCQLKTGMQGKADIISRRETVLRFILRKARLIADL

Specific function: Involved in the transport of the toxin RTX-III [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 78953; Mature: 78953

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLRRQENDFWHRSHQPIPEELPTLEANEFLPHIGKWTSIGGVVVFSIFIVGVVLTSVL
CCCCCCCCCHHHHCCCCCCHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
KYNVTVKVPATIRPVGELRLVQSLINGKILKISVAENQMVAEGQAIAYIDDSRLQTQKSQ
HHCEEEECCCCCCCHHHHHHHHHHHCCEEEEEEECCCCHHHCCCEEEEECCHHHHHHHHH
LQNLIQQSQLQLNKIDAQLGEIDAQITAQTNLNDRTTIAAQAELSGTQRNYADQQVKATA
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEHHHCCCHHHHHHHHHHHHH
DMTQAQSALTLARIQKDRLQREKLLTATVRETEAALQLARVQSDRLQREKLLKTTVDEAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGLKLAREQRDRLRRDRLLRTTVQETQTALNLAKAQQERLQREQLLAKTVQEAETALNLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVQRDRLQQDRVLTATVQEAEAALSLARVQRERLQPIVASGAIARSFFEEKDQAVISAEA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLEQAKANAKNLLEEKEQAVIAAEAKLEQAKANAKNLLEEKEQAVKSAEAKLEQAKANAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLLEEKDQGVIAAEAKLEQAKANAKNLLEEKEQEVIAAEAKLEQAKANAKNLQEEKDQAL
HHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVAQTNLAKARTAINPNDANVTVASERIKQEQARGEVTLAALKKERETLLQQRLEFQKQL
HHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
DRNRKELQQAENDLKQSIVRAPIAGTVLQLNLRNPGQVVQPSEAIAQIAPLNAPIQIKAN
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEEC
VQAQDINKVKPGQQVQMQVSACPYPDYGTLKGTVKTIAPDALPVANNNPQTTTAKATAYE
CCHHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCEECCEEEE
VIVEPQTPYVGRGDRQCQLKTGMQGKADIISRRETVLRFILRKARLIADL
EEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTLRRQENDFWHRSHQPIPEELPTLEANEFLPHIGKWTSIGGVVVFSIFIVGVVLTSVL
CCCCCCCCCHHHHCCCCCCHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
KYNVTVKVPATIRPVGELRLVQSLINGKILKISVAENQMVAEGQAIAYIDDSRLQTQKSQ
HHCEEEECCCCCCCHHHHHHHHHHHCCEEEEEEECCCCHHHCCCEEEEECCHHHHHHHHH
LQNLIQQSQLQLNKIDAQLGEIDAQITAQTNLNDRTTIAAQAELSGTQRNYADQQVKATA
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEHHHCCCHHHHHHHHHHHHH
DMTQAQSALTLARIQKDRLQREKLLTATVRETEAALQLARVQSDRLQREKLLKTTVDEAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGLKLAREQRDRLRRDRLLRTTVQETQTALNLAKAQQERLQREQLLAKTVQEAETALNLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVQRDRLQQDRVLTATVQEAEAALSLARVQRERLQPIVASGAIARSFFEEKDQAVISAEA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLEQAKANAKNLLEEKEQAVIAAEAKLEQAKANAKNLLEEKEQAVKSAEAKLEQAKANAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLLEEKDQGVIAAEAKLEQAKANAKNLLEEKEQEVIAAEAKLEQAKANAKNLQEEKDQAL
HHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVAQTNLAKARTAINPNDANVTVASERIKQEQARGEVTLAALKKERETLLQQRLEFQKQL
HHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
DRNRKELQQAENDLKQSIVRAPIAGTVLQLNLRNPGQVVQPSEAIAQIAPLNAPIQIKAN
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEEC
VQAQDINKVKPGQQVQMQVSACPYPDYGTLKGTVKTIAPDALPVANNNPQTTTAKATAYE
CCHHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCEECCEEEE
VIVEPQTPYVGRGDRQCQLKTGMQGKADIISRRETVLRFILRKARLIADL
EEECCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8494611; 7927703 [H]