Click here to switch to the map view.

The map label for this gene is 17228592

Identifier: 17228592

GI number: 17228592

Start: 1285583

End: 1286713

Strand: Direct

Name: 17228592

Synonym: alr1097

Alternate gene names: NA

Gene position: 1285583-1286713 (Clockwise)

Preceding gene: 17228591

Following gene: 17228597

Centisome position: 20.04

GC content: 39.79

Gene sequence:

>1131_bases
ATGAGCCTGAATCAACAAACCAAAAGTAATCTCAGCTTTTTTGAAAAATACCTCACTTTGTGGGTGTTTTTGTGCATCTT
TGTCGGCATAGCTTTAGGCAGATTATTTCCAGAGTTAGCGGTAAAACTAGATGCTATCAGTGTCTATCAAGTATCAATTC
CTATTGCAGTATGTCTATTTTTCATGATGTATCCCATCATGGTGAAGATAGACTTTACGCAAGCGATGAATGCGCTGCGT
ACCCCAAAACCTGTAATTCTTACCTTGGTGGTGAACTGGTTAATTAAACCATTCACGATGGTGGCCTTTTCTCAGTTCTT
TTTAGGCTGGTTGTTTCGTCCCTTAATTACGGGTACAGAATTAATTCGTGGTGGTGAAGTAGCGATCGCCAATTCTTACA
TAGCTGGGACGATTTTACTAGGGATTGCCCCTTGTACAGCAATGGTTTTGATGTGGGGTTATCTTTCCTATGGGAATCAA
GGTCACACTTTGGTGATGGTGGCTGTTAATTCTCTAGCAATGCTATTTTTGTATGCACCTTTGGGAAGGTGGTTACTAGC
AGCAAATGATTTAACTGTGCCTTGGCAAACTATAGTTTTATCTGTTTTAATTTACGTTGGCTTGCCATTAATTGCTGGCA
TATATAGCCGTTACTGGATTTTTAAATATAAAGGTAAAGAATGGTTTGAAAGTCGCTTTCTCAAATATCTTAGCCCCATT
GCTATTACGGCTTTGCTATTGACTTTAATCTTGTTATTTGCCTTTAAGGGCGAATTAATAGTTAAAAATCCCCTACATAT
TTTGTTGATAGCTGTACCACTATTTATTCAAACTAATTTCATCTTTTTAATTAGTTATGTAGCAGCCTTAAAGCTGAATC
TTGCTTACGAAGATGCTGCACCAGCCGCCTTAATTGGAGCTAGCAATCATTTTGAAGTGGCGATCGCTACAGCCGTAATG
CTGTTTGGTTTGAACTCTGGCGCTGCACTTGCCACAGTCGTGGGTGTTTTAATTGAAGTTCCCGTTATGTTGATGTTAGT
CGAGTTATGCAAACGTACAGCATCTTGGTTCCCCCGCCAGCCGGAAAAGGCAACTTTACGAGATCCACGGTGTATCACTT
CTTTTCATTGA

Upstream 100 bases:

>100_bases
CGTTTTTGGTATTAGGTGCAGCCGTAGTTTCCCTGAGATTACCAGATCCTAAACCAAGTAGAGCGAGCGCCTGGAAAGCT
GGAGACGGAGATTAAAAGCA

Downstream 100 bases:

>100_bases
GGTAGTGTCAAAGCGTTTCTGTTTATCTTCTGTAAGAGGGAGAAATCATGAAAAAAGTCATGTTTGTATGTAAGTATTTG
TAGCGACTGTCTTGAAAGTC

Product: multidrug-efflux transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MSLNQQTKSNLSFFEKYLTLWVFLCIFVGIALGRLFPELAVKLDAISVYQVSIPIAVCLFFMMYPIMVKIDFTQAMNALR
TPKPVILTLVVNWLIKPFTMVAFSQFFLGWLFRPLITGTELIRGGEVAIANSYIAGTILLGIAPCTAMVLMWGYLSYGNQ
GHTLVMVAVNSLAMLFLYAPLGRWLLAANDLTVPWQTIVLSVLIYVGLPLIAGIYSRYWIFKYKGKEWFESRFLKYLSPI
AITALLLTLILLFAFKGELIVKNPLHILLIAVPLFIQTNFIFLISYVAALKLNLAYEDAAPAALIGASNHFEVAIATAVM
LFGLNSGAALATVVGVLIEVPVMLMLVELCKRTASWFPRQPEKATLRDPRCITSFH

Sequences:

>Translated_376_residues
MSLNQQTKSNLSFFEKYLTLWVFLCIFVGIALGRLFPELAVKLDAISVYQVSIPIAVCLFFMMYPIMVKIDFTQAMNALR
TPKPVILTLVVNWLIKPFTMVAFSQFFLGWLFRPLITGTELIRGGEVAIANSYIAGTILLGIAPCTAMVLMWGYLSYGNQ
GHTLVMVAVNSLAMLFLYAPLGRWLLAANDLTVPWQTIVLSVLIYVGLPLIAGIYSRYWIFKYKGKEWFESRFLKYLSPI
AITALLLTLILLFAFKGELIVKNPLHILLIAVPLFIQTNFIFLISYVAALKLNLAYEDAAPAALIGASNHFEVAIATAVM
LFGLNSGAALATVVGVLIEVPVMLMLVELCKRTASWFPRQPEKATLRDPRCITSFH
>Mature_375_residues
SLNQQTKSNLSFFEKYLTLWVFLCIFVGIALGRLFPELAVKLDAISVYQVSIPIAVCLFFMMYPIMVKIDFTQAMNALRT
PKPVILTLVVNWLIKPFTMVAFSQFFLGWLFRPLITGTELIRGGEVAIANSYIAGTILLGIAPCTAMVLMWGYLSYGNQG
HTLVMVAVNSLAMLFLYAPLGRWLLAANDLTVPWQTIVLSVLIYVGLPLIAGIYSRYWIFKYKGKEWFESRFLKYLSPIA
ITALLLTLILLFAFKGELIVKNPLHILLIAVPLFIQTNFIFLISYVAALKLNLAYEDAAPAALIGASNHFEVAIATAVML
FGLNSGAALATVVGVLIEVPVMLMLVELCKRTASWFPRQPEKATLRDPRCITSFH

Specific function: Unknown

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=334, Percent_Identity=28.7425149700599, Blast_Score=95, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 41952; Mature: 41821

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNQQTKSNLSFFEKYLTLWVFLCIFVGIALGRLFPELAVKLDAISVYQVSIPIAVCLF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHH
FMMYPIMVKIDFTQAMNALRTPKPVILTLVVNWLIKPFTMVAFSQFFLGWLFRPLITGTE
HHHHHHHEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIRGGEVAIANSYIAGTILLGIAPCTAMVLMWGYLSYGNQGHTLVMVAVNSLAMLFLYAP
HHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHH
LGRWLLAANDLTVPWQTIVLSVLIYVGLPLIAGIYSRYWIFKYKGKEWFESRFLKYLSPI
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHH
AITALLLTLILLFAFKGELIVKNPLHILLIAVPLFIQTNFIFLISYVAALKLNLAYEDAA
HHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCC
PAALIGASNHFEVAIATAVMLFGLNSGAALATVVGVLIEVPVMLMLVELCKRTASWFPRQ
CEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PEKATLRDPRCITSFH
CCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLNQQTKSNLSFFEKYLTLWVFLCIFVGIALGRLFPELAVKLDAISVYQVSIPIAVCLF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHH
FMMYPIMVKIDFTQAMNALRTPKPVILTLVVNWLIKPFTMVAFSQFFLGWLFRPLITGTE
HHHHHHHEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIRGGEVAIANSYIAGTILLGIAPCTAMVLMWGYLSYGNQGHTLVMVAVNSLAMLFLYAP
HHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHH
LGRWLLAANDLTVPWQTIVLSVLIYVGLPLIAGIYSRYWIFKYKGKEWFESRFLKYLSPI
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHH
AITALLLTLILLFAFKGELIVKNPLHILLIAVPLFIQTNFIFLISYVAALKLNLAYEDAA
HHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCC
PAALIGASNHFEVAIATAVMLFGLNSGAALATVVGVLIEVPVMLMLVELCKRTASWFPRQ
CEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PEKATLRDPRCITSFH
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]