| Definition | Ureaplasma parvum serovar 3 str. ATCC 27815 chromosome, complete genome. |
|---|---|
| Accession | NC_010503 |
| Length | 751,679 |
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The map label for this gene is gyrB
Identifier: 170762124
GI number: 170762124
Start: 97123
End: 99075
Strand: Direct
Name: gyrB
Synonym: UPA3_0080
Alternate gene names: 170762124
Gene position: 97123-99075 (Clockwise)
Preceding gene: 170762045
Following gene: 170761893
Centisome position: 12.92
GC content: 30.72
Gene sequence:
>1953_bases ATGAACGATTCTAATAAAGAAAAAAAATACACCGCCGAAAGTATTAAAGTACTAGAAGGTTTAGAAGCAGTACGAAAACG TCCTGGTATGTACATTGGTTCAACCCAATCAGAGGGTCTACACCATATGATTTGAGAAATTGTTGATAATTCAATTGATG AGGCTATGGGCGGATTTGCAACAATTGTTAGAGTTATTCTAAAAAAAGACGGATCAGTACGTGTAGAAGATGATGGACGC GGAATTCCAATTGAAATTCACGAAAAAACAGGCTTATCAGGTGTTGAAACAGTATTAACAGTTTTACATGCTGGTGGTAA GTTTGATAATGATAGTTATAAAGTGTCTGGTGGATTACATGGTGTTGGTGCCTCTGTTGTTAATGCTTTAAGTAAAAATT TTAAGGTTTGAGTAAACAAGAATCATGTTCAATATTATGTTGAATTTATCAATGGCGGTCATGCTATTGAGCCACTAAAA CCGATTAATAATAAAGATGTTAAAGAAAAAGGAACAACAATTGAATTTATTCCAGATTTTGAAATTATGGAAGAAAATGA GTGAGATGAGCTTAAAATAATGGCTCGTTTAAAGCAATTAGCTTATCTTAACAAAGGTGTTAACATTGAATTTGAATCAG AATTAACTAACCGTAAAGAAAAATGACATTATGAAGGTGGTTTAAAAGAATATATAACAGATTTAAATGCTGAAAAAGAA CCATTATTTGATTTAATTGTTTATGGAGAAGAAGAAAAAGAAGTTAGAGTTCCAGGACATAACGAGCAAACTTATAACAT TAAATGTGAAGTTGCATTTCAATATAATAATTCATACAATAACTCAACCCATTCATTTTGTAATAACATCAATACCACTG AAGGTGGAACACACGAAGAAGGTTTTAAATTAGCGATTACGCGTTTATTAAATAAATATGCGGTCGATAAAAAATATTTA AAAGACACTGATGATAAAATCACTAAAGAAGACGTTAGTGAAGGATTAACAGCAATTATTTCAGTTAAGCATCCTAATCC TCAATATGAAGGTCAAACAAAAAAGAAATTAGGTAATAGTGAAGTTCGTCCTTATGTTAATGAAATCACATCTATTATTT TTGAAAAATTTTTAAATGAAAATCCTGAAGAATCAAAAAAAATTGTTGCTAAGGTTATGCAAGCTGCTGAAGCACGACGA CGTTCACATGAAGCACGTGAAGCTACACGGCGTAAATCACCTTTTGAATCAAATTCATTACCTGGTAAATTAGCTGACTG CTCAAATCGTGATTCAAGTGTTACTGAAATTTATATTGTCGAAGGAGATTCAGCGGGTGGTTCAGCAAAAACAGGTCGTG AGCGTGAATTTCAAGCAATTTTACCACTGCGTGGAAAGATTATTAATGTTGAAAAAGCTAAAATTGATAAGATTTTTGCT AATGAAGAAATTCAAAATATGATTACTGCTTTTGGAGCAGGAATAGGTCCTGAATTTAATATTGAAAAATTAAGATATTC AAAAATTATTATTATGACTGATGCGGATGTTGATGGCAGTCATATTCGAATTTTATTGCTAACATTTTTTTATCGATACA TGTTGCCATTGATTCAAAATGGAAATGTTTATATAGCGCAACCACCATTGTATAAAGTAAGTTATGCTAAAACAATTAAA TACGCATATTCTGATCAAGAGTTAGAAAGAATTAAATCAACAATATCAAATATTAAATATAACATTCAACGCTATAAAGG GTTAGGTGAAATGAATCCTGATCAATTGTGAGAAACAACAATGGATCCTAAAAATAGACTTTTATTAAAAGTTAATATTG AAGACGCTGCAATTGCTGATAAAACATTTTCTCTATTAATGGGTGATGATGTAGCTCCAAGAAAAGAATTTATTGAAAAA AATGCAAAATATGTAAAAAATATTGATGCTTAA
Upstream 100 bases:
>100_bases TAGAAAATAGACGTGGTCGTAAATTATATGATCAAATGATTATTAAAATAAAAAATCAATTGTATCAAATAGTTAAAACT AATGAGTAGATAGGAGTTTT
Downstream 100 bases:
>100_bases AATTGAGGTATATAAAATATTATGGCATTAAAAAAACCAAAAAAAAGTCGTTTAACCACCGAAGAAATTAAGCAACAATT AGAAGGTTCAACGATTAAAG
Product: DNA gyrase subunit B
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 650; Mature: 650
Protein sequence:
>650_residues MNDSNKEKKYTAESIKVLEGLEAVRKRPGMYIGSTQSEGLHHMIWEIVDNSIDEAMGGFATIVRVILKKDGSVRVEDDGR GIPIEIHEKTGLSGVETVLTVLHAGGKFDNDSYKVSGGLHGVGASVVNALSKNFKVWVNKNHVQYYVEFINGGHAIEPLK PINNKDVKEKGTTIEFIPDFEIMEENEWDELKIMARLKQLAYLNKGVNIEFESELTNRKEKWHYEGGLKEYITDLNAEKE PLFDLIVYGEEEKEVRVPGHNEQTYNIKCEVAFQYNNSYNNSTHSFCNNINTTEGGTHEEGFKLAITRLLNKYAVDKKYL KDTDDKITKEDVSEGLTAIISVKHPNPQYEGQTKKKLGNSEVRPYVNEITSIIFEKFLNENPEESKKIVAKVMQAAEARR RSHEAREATRRKSPFESNSLPGKLADCSNRDSSVTEIYIVEGDSAGGSAKTGREREFQAILPLRGKIINVEKAKIDKIFA NEEIQNMITAFGAGIGPEFNIEKLRYSKIIIMTDADVDGSHIRILLLTFFYRYMLPLIQNGNVYIAQPPLYKVSYAKTIK YAYSDQELERIKSTISNIKYNIQRYKGLGEMNPDQLWETTMDPKNRLLLKVNIEDAAIADKTFSLLMGDDVAPRKEFIEK NAKYVKNIDA
Sequences:
>Translated_650_residues MNDSNKEKKYTAESIKVLEGLEAVRKRPGMYIGSTQSEGLHHMI*EIVDNSIDEAMGGFATIVRVILKKDGSVRVEDDGR GIPIEIHEKTGLSGVETVLTVLHAGGKFDNDSYKVSGGLHGVGASVVNALSKNFKV*VNKNHVQYYVEFINGGHAIEPLK PINNKDVKEKGTTIEFIPDFEIMEENE*DELKIMARLKQLAYLNKGVNIEFESELTNRKEK*HYEGGLKEYITDLNAEKE PLFDLIVYGEEEKEVRVPGHNEQTYNIKCEVAFQYNNSYNNSTHSFCNNINTTEGGTHEEGFKLAITRLLNKYAVDKKYL KDTDDKITKEDVSEGLTAIISVKHPNPQYEGQTKKKLGNSEVRPYVNEITSIIFEKFLNENPEESKKIVAKVMQAAEARR RSHEAREATRRKSPFESNSLPGKLADCSNRDSSVTEIYIVEGDSAGGSAKTGREREFQAILPLRGKIINVEKAKIDKIFA NEEIQNMITAFGAGIGPEFNIEKLRYSKIIIMTDADVDGSHIRILLLTFFYRYMLPLIQNGNVYIAQPPLYKVSYAKTIK YAYSDQELERIKSTISNIKYNIQRYKGLGEMNPDQL*ETTMDPKNRLLLKVNIEDAAIADKTFSLLMGDDVAPRKEFIEK NAKYVKNIDA >Mature_650_residues MNDSNKEKKYTAESIKVLEGLEAVRKRPGMYIGSTQSEGLHHMI*EIVDNSIDEAMGGFATIVRVILKKDGSVRVEDDGR GIPIEIHEKTGLSGVETVLTVLHAGGKFDNDSYKVSGGLHGVGASVVNALSKNFKV*VNKNHVQYYVEFINGGHAIEPLK PINNKDVKEKGTTIEFIPDFEIMEENE*DELKIMARLKQLAYLNKGVNIEFESELTNRKEK*HYEGGLKEYITDLNAEKE PLFDLIVYGEEEKEVRVPGHNEQTYNIKCEVAFQYNNSYNNSTHSFCNNINTTEGGTHEEGFKLAITRLLNKYAVDKKYL KDTDDKITKEDVSEGLTAIISVKHPNPQYEGQTKKKLGNSEVRPYVNEITSIIFEKFLNENPEESKKIVAKVMQAAEARR RSHEAREATRRKSPFESNSLPGKLADCSNRDSSVTEIYIVEGDSAGGSAKTGREREFQAILPLRGKIINVEKAKIDKIFA NEEIQNMITAFGAGIGPEFNIEKLRYSKIIIMTDADVDGSHIRILLLTFFYRYMLPLIQNGNVYIAQPPLYKVSYAKTIK YAYSDQELERIKSTISNIKYNIQRYKGLGEMNPDQL*ETTMDPKNRLLLKVNIEDAAIADKTFSLLMGDDVAPRKEFIEK NAKYVKNIDA
Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]
COG id: COG0187
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 Toprim domain [H]
Homologues:
Organism=Homo sapiens, GI19913406, Length=613, Percent_Identity=26.9168026101142, Blast_Score=129, Evalue=6e-30, Organism=Homo sapiens, GI19913408, Length=693, Percent_Identity=25.3968253968254, Blast_Score=118, Evalue=2e-26, Organism=Escherichia coli, GI48994957, Length=574, Percent_Identity=48.6062717770035, Blast_Score=503, Evalue=1e-143, Organism=Escherichia coli, GI1789408, Length=613, Percent_Identity=38.1729200652529, Blast_Score=398, Evalue=1e-112, Organism=Caenorhabditis elegans, GI212645845, Length=555, Percent_Identity=25.5855855855856, Blast_Score=132, Evalue=5e-31, Organism=Caenorhabditis elegans, GI17535065, Length=617, Percent_Identity=26.742301458671, Blast_Score=131, Evalue=1e-30, Organism=Caenorhabditis elegans, GI212645657, Length=199, Percent_Identity=28.1407035175879, Blast_Score=74, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6324241, Length=669, Percent_Identity=26.0089686098655, Blast_Score=122, Evalue=2e-28, Organism=Drosophila melanogaster, GI17136538, Length=656, Percent_Identity=25.609756097561, Blast_Score=124, Evalue=2e-28,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR011557 - InterPro: IPR020568 - InterPro: IPR014721 - InterPro: IPR001241 - InterPro: IPR013759 - InterPro: IPR002288 - InterPro: IPR013506 - InterPro: IPR013760 - InterPro: IPR018522 - InterPro: IPR006171 [H]
Pfam domain/function: PF00204 DNA_gyraseB; PF00986 DNA_gyraseB_C; PF02518 HATPase_c; PF01751 Toprim [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 72709; Mature: 72709
Theoretical pI: Translated: 6.31; Mature: 6.31
Prosite motif: PS00177 TOPOISOMERASE_II
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNDSNKEKKYTAESIKVLEGLEAVRKRPGMYIGSTQSEGLHHMIEIVDNSIDEAMGGFAT CCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH IVRVILKKDGSVRVEDDGRGIPIEIHEKTGLSGVETVLTVLHAGGKFDNDSYKVSGGLHG HHHHHHHCCCCEEECCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCEEECCCCCH VGASVVNALSKNFKVVNKNHVQYYVEFINGGHAIEPLKPINNKDVKEKGTTIEFIPDFEI HHHHHHHHHHHCCEEECCCHHEEEEEECCCCCCCCCCCCCCCCCCHHCCCEEEEECCCHH MEENEDELKIMARLKQLAYLNKGVNIEFESELTNRKEKHYEGGLKEYITDLNAEKEPLFD HCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEE LIVYGEEEKEVRVPGHNEQTYNIKCEVAFQYNNSYNNSTHSFCNNINTTEGGTHEEGFKL EEEECCCCCEEECCCCCCCEEEEEEEEEEEECCCCCCCHHHHHCCCCCCCCCCCCCHHHH AITRLLNKYAVDKKYLKDTDDKITKEDVSEGLTAIISVKHPNPQYEGQTKKKLGNSEVRP HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHCCCCCCHH YVNEITSIIFEKFLNENPEESKKIVAKVMQAAEARRRSHEAREATRRKSPFESNSLPGKL HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC ADCSNRDSSVTEIYIVEGDSAGGSAKTGREREFQAILPLRGKIINVEKAKIDKIFANEEI CCCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHEECCCCCEEEECHHHHHHHHHCCHHH QNMITAFGAGIGPEFNIEKLRYSKIIIMTDADVDGSHIRILLLTFFYRYMLPLIQNGNVY HHHHHHHCCCCCCCCCHHEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE IAQPPLYKVSYAKTIKYAYSDQELERIKSTISNIKYNIQRYKGLGEMNPDQLETTMDPKN EECCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCC RLLLKVNIEDAAIADKTFSLLMGDDVAPRKEFIEKNAKYVKNIDA CEEEEEECCHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCCC >Mature Secondary Structure MNDSNKEKKYTAESIKVLEGLEAVRKRPGMYIGSTQSEGLHHMIEIVDNSIDEAMGGFAT CCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH IVRVILKKDGSVRVEDDGRGIPIEIHEKTGLSGVETVLTVLHAGGKFDNDSYKVSGGLHG HHHHHHHCCCCEEECCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCEEECCCCCH VGASVVNALSKNFKVVNKNHVQYYVEFINGGHAIEPLKPINNKDVKEKGTTIEFIPDFEI HHHHHHHHHHHCCEEECCCHHEEEEEECCCCCCCCCCCCCCCCCCHHCCCEEEEECCCHH MEENEDELKIMARLKQLAYLNKGVNIEFESELTNRKEKHYEGGLKEYITDLNAEKEPLFD HCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEE LIVYGEEEKEVRVPGHNEQTYNIKCEVAFQYNNSYNNSTHSFCNNINTTEGGTHEEGFKL EEEECCCCCEEECCCCCCCEEEEEEEEEEEECCCCCCCHHHHHCCCCCCCCCCCCCHHHH AITRLLNKYAVDKKYLKDTDDKITKEDVSEGLTAIISVKHPNPQYEGQTKKKLGNSEVRP HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHCCCCCCHH YVNEITSIIFEKFLNENPEESKKIVAKVMQAAEARRRSHEAREATRRKSPFESNSLPGKL HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC ADCSNRDSSVTEIYIVEGDSAGGSAKTGREREFQAILPLRGKIINVEKAKIDKIFANEEI CCCCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHEECCCCCEEEECHHHHHHHHHCCHHH QNMITAFGAGIGPEFNIEKLRYSKIIIMTDADVDGSHIRILLLTFFYRYMLPLIQNGNVY HHHHHHHCCCCCCCCCHHEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCEE IAQPPLYKVSYAKTIKYAYSDQELERIKSTISNIKYNIQRYKGLGEMNPDQLETTMDPKN EECCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCC RLLLKVNIEDAAIADKTFSLLMGDDVAPRKEFIEKNAKYVKNIDA CEEEEEECCHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8083173; 7569993; 8253680 [H]