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The map label for this gene is infC

Identifier: 170761849

GI number: 170761849

Start: 274443

End: 275006

Strand: Direct

Name: infC

Synonym: UPA3_0235

Alternate gene names: 170761849

Gene position: 274443-275006 (Clockwise)

Preceding gene: 170762430

Following gene: 170762449

Centisome position: 36.51

GC content: 27.66

Gene sequence:

>564_bases
ATGAATACACCAAACAATCAACGCCATATGTCATCAAATAATGATGCACGTAAAAATCAACCTTTAATTAATGATCAAAT
TCGTTTTCGAACAATGGTTGTAATTGATGACCATGGTAATAATTTAGGTGAAATGAATCGTATTGATGCCCTTAATTTAG
CCGCTTCAAAGAATTTAGATTTAGTTGTTATTGCTAAAAAAGGAAATATTCCTGTAACAAAAATTTTAGATTATGGTAAG
TACAAATACGAACAAAAACGTCGTCAAAAAGAATCAAGAAAAAATCAAACAATTATTAAGGTAAAAGAAATCAAAATTAA
ACCAATGATTGGTGAACATGATTTAAAAGTAAGAGCAGAAAATGCTAAACGTTGATTAGAAGATAAAGACAACGTGAAAT
TTGTGATTGAAGCACGTGGACGTATGTGTACAAAAGATGAATTTATTGTACAAGCTTATGAAAAATTCATTGACTTAATT
AAAGATTATGGTACAGTTGTTCAAGCTAATAAAAAAGTTAGCAATTATCGATATGAAACAATTATTGAACCAATTAAAAA
ATAA

Upstream 100 bases:

>100_bases
AATAGGTTAATGCTTAATATTTCGATTATTACATCATTTATTCATGTTATAGATATAAATGATTTTCTTTATACATTTAA
TTTTTAATTAGGAGTGTTTA

Downstream 100 bases:

>100_bases
GGAAGGTAACTATAATGGCTAAAATTAGACAAAAAACAAAAAGAGCTGTTGCAAAACGTTTTAGTATTACAAAAAATGGT
AAATTAAAACGTAAACACGC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MNTPNNQRHMSSNNDARKNQPLINDQIRFRTMVVIDDHGNNLGEMNRIDALNLAASKNLDLVVIAKKGNIPVTKILDYGK
YKYEQKRRQKESRKNQTIIKVKEIKIKPMIGEHDLKVRAENAKRWLEDKDNVKFVIEARGRMCTKDEFIVQAYEKFIDLI
KDYGTVVQANKKVSNYRYETIIEPIKK

Sequences:

>Translated_187_residues
MNTPNNQRHMSSNNDARKNQPLINDQIRFRTMVVIDDHGNNLGEMNRIDALNLAASKNLDLVVIAKKGNIPVTKILDYGK
YKYEQKRRQKESRKNQTIIKVKEIKIKPMIGEHDLKVRAENAKR*LEDKDNVKFVIEARGRMCTKDEFIVQAYEKFIDLI
KDYGTVVQANKKVSNYRYETIIEPIKK
>Mature_187_residues
MNTPNNQRHMSSNNDARKNQPLINDQIRFRTMVVIDDHGNNLGEMNRIDALNLAASKNLDLVVIAKKGNIPVTKILDYGK
YKYEQKRRQKESRKNQTIIKVKEIKIKPMIGEHDLKVRAENAKR*LEDKDNVKFVIEARGRMCTKDEFIVQAYEKFIDLI
KDYGTVVQANKKVSNYRYETIIEPIKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=172, Percent_Identity=31.3953488372093, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 21701; Mature: 21701

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPNNQRHMSSNNDARKNQPLINDQIRFRTMVVIDDHGNNLGEMNRIDALNLAASKNLD
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHCCCCCC
LVVIAKKGNIPVTKILDYGKYKYEQKRRQKESRKNQTIIKVKEIKIKPMIGEHDLKVRAE
EEEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCEEEEEC
NAKRLEDKDNVKFVIEARGRMCTKDEFIVQAYEKFIDLIKDYGTVVQANKKVSNYRYETI
CHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHH
IEPIKK
HHHHCC
>Mature Secondary Structure
MNTPNNQRHMSSNNDARKNQPLINDQIRFRTMVVIDDHGNNLGEMNRIDALNLAASKNLD
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHCCCCCC
LVVIAKKGNIPVTKILDYGKYKYEQKRRQKESRKNQTIIKVKEIKIKPMIGEHDLKVRAE
EEEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCEEEEEC
NAKRLEDKDNVKFVIEARGRMCTKDEFIVQAYEKFIDLIKDYGTVVQANKKVSNYRYETI
CHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHH
IEPIKK
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11048724 [H]