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The map label for this gene is hbpA [H]

Identifier: 170757770

GI number: 170757770

Start: 924912

End: 927392

Strand: Reverse

Name: hbpA [H]

Synonym: CLD_3757

Alternate gene names: 170757770

Gene position: 927392-924912 (Counterclockwise)

Preceding gene: 170756046

Following gene: 170757526

Centisome position: 23.43

GC content: 27.01

Gene sequence:

>2481_bases
ATGTTTAATTTTAAATTAAAAAGATCTTCCATAGATAAAAATATTAATAGCTTAAATGAAAAAAATATAGAAAAGCCCTG
TAATATTGCAATCTATGAAGATAACTTAAAAGTTCTAACTAATAACCAAAGAAAAATAGTAGACAAACTTGATAAAAAAA
TAATAGAAACAGATTCTGTTACAGAATTACTAATTAAAATGACAAAGGATATATCTAATTACGTAGAAATGGAAATGGAT
TCTATATCTAAAGTTACAGGAGAAATAAGCAATTATTCTGCCATAGCAGAGGAGGTTTTTTCTAGTACAGAAAATTCAAA
GCAAATATCAGAAAGTACCATGGAAGTTGCTAAAGAAGGTAATGGAGCTGCTTTAAATTCCATAGAAGCTATGAAAGAAA
TAGAAGGATCTATGTTATATTCTAAAACAGTAGTAAAGGATTTAAGTACTAAAGCTTTAGATATTAACAATATGCTAGAT
GTAATAAAAGATATTGCAAACAATACTAATTTATTATCTTTAAATGCCTCTATTGAAGCTGCAAGAGCTGGTGAGGCTGG
TAAAGGCTTCGCAGTAGTTGCACATGAAGTAAAAAAACTAGCAGAAAGAAGTATGGATTCCGTTGATTTTATAGGAAATA
ATATAAAAGAAATAAATATTAGCATAGACAATGCTATAAAGGCTATAAATGAAACTATGAATAAAGTAAAAGAAGGTACC
GAAATAGCTAATAAAACTATGGAAACCTTCAACAGCATAATATCTTCTATAAAAACCAGTACCTCTGTATCTGAAGAAAT
TAATGATGCTATTACAAAACAAATTGGTCATTTAGAAAACGTTATTAACTCTACTGAAGAGATGAATACTACTTCTGAAA
AGTTAATGTTTATAGTAGAATTAGTTTCTTTAAATACTCAATATACCAAAACTTCTTTAAAGGATTTATCCGAGGTTTCC
CAAAACTTAAAATATATTAGTAATAATCTTTTACATGAAATAGAAGTTGATTCTAAAGAAAATAATGTAATTTTAAATAC
TTATATTGATGGTAGACCTCTATATTTAGATCCTGCTCTAAGCTATGAACTTAATAGTAGCCTTCTATTAAATAATATAC
ATATAGGTCTTTTAACCATAAACTCCTATGGAGAAATATCTCCTGGAATAGCTAAAAGTTGGTATTTAGAAAAGGATAAC
CTTACTTGGATTTTTAATCTTAAAAAAGGAATAAAATTTCATAATGGTAAAGAGGTTACCTCAGAAGATGTAAAATTTTC
ATTAGAAAGACTTTTAGATCCTAAACTTGACTCTCCTAACGGTTGGCTACTAGAAATTATAGAAGGATCTGAAGATTTTA
AAGAAGGTGCAGCAAAACATGTTTCTGGCATTAAGATATTGGATAAATATAGAATTTCTTTAACCTTATCCTATTCATAC
AGTGGATTTTTATTAAATCTTGGATTAGAACTTTGCGGTATAATAAATAAGGATTCTATAAATCAGGGGGATGTAGTAGG
CTGTGGCCCTTATAAAATATCCGAATTTAATGATGAAGGATGCAAACTAGAGGCCTTCAAAGAATATTTTAATGGAGCTC
CTTATATTGATATTATAAATATTAATTTTAAATCTGAATCTCCTATAGATGATTTCTTAAATAAAGATTTAGATGTATTA
ACCATAAATGATAAAAACGAATATACAACTTTATGTTCTAATAAAAATATAAATCTTATAGAGCAAGATTTACTAGCAAC
TTACTATGCTAGTTTTAACATGAAATCCAACTCTATTTTTTCTAGGGATAAAGATGTAAGATATGCTCTTAACTTAGCTA
TAGACAAGAATAGAATAATAAAGGATATATTAGGTGGATTGGGAGTTGAAGCAAAGGGTCCTTTCCCTCCAAGCATAATA
CCTAATAATAAGTTAAAAGGTTTTTCTCATAATAAATCTAAAGCCAAAGAAATTCTTTCTAGAAGTGATTTTAATAGATC
CCGAGATAAATTAAATATATTAATCCGAAAAGACGAGGATTCTTTATTTTCTAAAATAACAGAATATATATTAGAAGATT
TAAAAAATATAGGAATAGATTGTATTGTAAAAGAAGTAAATTCTTCTGAATACTTAAATTTAGATAATATTTTAAAATGT
GACATGGCTATAAGCAGATGGTGCGCTGATTCTGGAGATCCTGATAATTTCTTAGAACCAATATTTAATATAGAAAATGT
GTCTAACATATCTAGGTATGACAATAAACTAGTAAATGAAAAATTAGAAATAGCTAAAAACTTAATTAATCCTGAAAAAA
GGAAAAAATTATATGAAGAAATACAGGAAATTATAGTAGAGGATGTTCCATGGATATTTTTATATCATCCTAAACTAGCT
ATAGCTGTACAAAATAATATACTTGGATTGAATGCTAATCCTTTAGGACTTTTCAAATATGAAGATATAATAAAAAATTA
G

Upstream 100 bases:

>100_bases
TTTTAAAAATTATATTTAAATGAATATTTTTCATACTTTAACAAATTATTTAAATGAGTTAAAATGTTGGTAGTAACTAT
TATTTTATAGGGGGATTGAA

Downstream 100 bases:

>100_bases
ATACCTCATATTTTTATCTTGTGAAAAGGGTTGTCTCAAAATAGATTTAATTTTGAGACAACTTTTAGTTTTATTATATT
AAAAATCCGCTGCTTGTGGA

Product: methyl-accepting chemotaxis protein/ extracellular solute-binding protein family 5

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 826; Mature: 826

Protein sequence:

>826_residues
MFNFKLKRSSIDKNINSLNEKNIEKPCNIAIYEDNLKVLTNNQRKIVDKLDKKIIETDSVTELLIKMTKDISNYVEMEMD
SISKVTGEISNYSAIAEEVFSSTENSKQISESTMEVAKEGNGAALNSIEAMKEIEGSMLYSKTVVKDLSTKALDINNMLD
VIKDIANNTNLLSLNASIEAARAGEAGKGFAVVAHEVKKLAERSMDSVDFIGNNIKEINISIDNAIKAINETMNKVKEGT
EIANKTMETFNSIISSIKTSTSVSEEINDAITKQIGHLENVINSTEEMNTTSEKLMFIVELVSLNTQYTKTSLKDLSEVS
QNLKYISNNLLHEIEVDSKENNVILNTYIDGRPLYLDPALSYELNSSLLLNNIHIGLLTINSYGEISPGIAKSWYLEKDN
LTWIFNLKKGIKFHNGKEVTSEDVKFSLERLLDPKLDSPNGWLLEIIEGSEDFKEGAAKHVSGIKILDKYRISLTLSYSY
SGFLLNLGLELCGIINKDSINQGDVVGCGPYKISEFNDEGCKLEAFKEYFNGAPYIDIININFKSESPIDDFLNKDLDVL
TINDKNEYTTLCSNKNINLIEQDLLATYYASFNMKSNSIFSRDKDVRYALNLAIDKNRIIKDILGGLGVEAKGPFPPSII
PNNKLKGFSHNKSKAKEILSRSDFNRSRDKLNILIRKDEDSLFSKITEYILEDLKNIGIDCIVKEVNSSEYLNLDNILKC
DMAISRWCADSGDPDNFLEPIFNIENVSNISRYDNKLVNEKLEIAKNLINPEKRKKLYEEIQEIIVEDVPWIFLYHPKLA
IAVQNNILGLNANPLGLFKYEDIIKN

Sequences:

>Translated_826_residues
MFNFKLKRSSIDKNINSLNEKNIEKPCNIAIYEDNLKVLTNNQRKIVDKLDKKIIETDSVTELLIKMTKDISNYVEMEMD
SISKVTGEISNYSAIAEEVFSSTENSKQISESTMEVAKEGNGAALNSIEAMKEIEGSMLYSKTVVKDLSTKALDINNMLD
VIKDIANNTNLLSLNASIEAARAGEAGKGFAVVAHEVKKLAERSMDSVDFIGNNIKEINISIDNAIKAINETMNKVKEGT
EIANKTMETFNSIISSIKTSTSVSEEINDAITKQIGHLENVINSTEEMNTTSEKLMFIVELVSLNTQYTKTSLKDLSEVS
QNLKYISNNLLHEIEVDSKENNVILNTYIDGRPLYLDPALSYELNSSLLLNNIHIGLLTINSYGEISPGIAKSWYLEKDN
LTWIFNLKKGIKFHNGKEVTSEDVKFSLERLLDPKLDSPNGWLLEIIEGSEDFKEGAAKHVSGIKILDKYRISLTLSYSY
SGFLLNLGLELCGIINKDSINQGDVVGCGPYKISEFNDEGCKLEAFKEYFNGAPYIDIININFKSESPIDDFLNKDLDVL
TINDKNEYTTLCSNKNINLIEQDLLATYYASFNMKSNSIFSRDKDVRYALNLAIDKNRIIKDILGGLGVEAKGPFPPSII
PNNKLKGFSHNKSKAKEILSRSDFNRSRDKLNILIRKDEDSLFSKITEYILEDLKNIGIDCIVKEVNSSEYLNLDNILKC
DMAISRWCADSGDPDNFLEPIFNIENVSNISRYDNKLVNEKLEIAKNLINPEKRKKLYEEIQEIIVEDVPWIFLYHPKLA
IAVQNNILGLNANPLGLFKYEDIIKN
>Mature_826_residues
MFNFKLKRSSIDKNINSLNEKNIEKPCNIAIYEDNLKVLTNNQRKIVDKLDKKIIETDSVTELLIKMTKDISNYVEMEMD
SISKVTGEISNYSAIAEEVFSSTENSKQISESTMEVAKEGNGAALNSIEAMKEIEGSMLYSKTVVKDLSTKALDINNMLD
VIKDIANNTNLLSLNASIEAARAGEAGKGFAVVAHEVKKLAERSMDSVDFIGNNIKEINISIDNAIKAINETMNKVKEGT
EIANKTMETFNSIISSIKTSTSVSEEINDAITKQIGHLENVINSTEEMNTTSEKLMFIVELVSLNTQYTKTSLKDLSEVS
QNLKYISNNLLHEIEVDSKENNVILNTYIDGRPLYLDPALSYELNSSLLLNNIHIGLLTINSYGEISPGIAKSWYLEKDN
LTWIFNLKKGIKFHNGKEVTSEDVKFSLERLLDPKLDSPNGWLLEIIEGSEDFKEGAAKHVSGIKILDKYRISLTLSYSY
SGFLLNLGLELCGIINKDSINQGDVVGCGPYKISEFNDEGCKLEAFKEYFNGAPYIDIININFKSESPIDDFLNKDLDVL
TINDKNEYTTLCSNKNINLIEQDLLATYYASFNMKSNSIFSRDKDVRYALNLAIDKNRIIKDILGGLGVEAKGPFPPSII
PNNKLKGFSHNKSKAKEILSRSDFNRSRDKLNILIRKDEDSLFSKITEYILEDLKNIGIDCIVKEVNSSEYLNLDNILKC
DMAISRWCADSGDPDNFLEPIFNIENVSNISRYDNKLVNEKLEIAKNLINPEKRKKLYEEIQEIIVEDVPWIFLYHPKLA
IAVQNNILGLNANPLGLFKYEDIIKN

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=510, Percent_Identity=24.3137254901961, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1787052, Length=495, Percent_Identity=24.8484848484848, Blast_Score=130, Evalue=4e-31,
Organism=Escherichia coli, GI87081878, Length=478, Percent_Identity=25.3138075313808, Blast_Score=126, Evalue=6e-30,
Organism=Escherichia coli, GI1787762, Length=488, Percent_Identity=23.3606557377049, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788194, Length=305, Percent_Identity=26.5573770491803, Blast_Score=99, Evalue=2e-21,
Organism=Escherichia coli, GI1787551, Length=472, Percent_Identity=22.8813559322034, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1789453, Length=275, Percent_Identity=25.4545454545455, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI2367378, Length=228, Percent_Identity=29.3859649122807, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1787495, Length=466, Percent_Identity=23.6051502145923, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788195, Length=264, Percent_Identity=26.5151515151515, Blast_Score=90, Evalue=7e-19,
Organism=Escherichia coli, GI1787690, Length=168, Percent_Identity=35.1190476190476, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1789887, Length=415, Percent_Identity=24.3373493975904, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 93010; Mature: 93010

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS01040 SBP_BACTERIAL_5 ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNFKLKRSSIDKNINSLNEKNIEKPCNIAIYEDNLKVLTNNQRKIVDKLDKKIIETDSV
CCCEEECHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCHHHHHHHHHHHHHCCCHH
TELLIKMTKDISNYVEMEMDSISKVTGEISNYSAIAEEVFSSTENSKQISESTMEVAKEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
NGAALNSIEAMKEIEGSMLYSKTVVKDLSTKALDINNMLDVIKDIANNTNLLSLNASIEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCH
ARAGEAGKGFAVVAHEVKKLAERSMDSVDFIGNNIKEINISIDNAIKAINETMNKVKEGT
HCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHHH
EIANKTMETFNSIISSIKTSTSVSEEINDAITKQIGHLENVINSTEEMNTTSEKLMFIVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LVSLNTQYTKTSLKDLSEVSQNLKYISNNLLHEIEVDSKENNVILNTYIDGRPLYLDPAL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEEEEEECCEEEEECCCC
SYELNSSLLLNNIHIGLLTINSYGEISPGIAKSWYLEKDNLTWIFNLKKGIKFHNGKEVT
CCCCCCCEEEEEEEEEEEEECCCCCCCCCCCCCEEEECCCEEEEEEECCCCEECCCCCCC
SEDVKFSLERLLDPKLDSPNGWLLEIIEGSEDFKEGAAKHVSGIKILDKYRISLTLSYSY
HHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEEEEEEEEEECC
SGFLLNLGLELCGIINKDSINQGDVVGCGPYKISEFNDEGCKLEAFKEYFNGAPYIDIIN
CCHHHHCCHHHHCCCCCCCCCCCCEEECCCEEECCCCCCCCHHHHHHHHHCCCCEEEEEE
INFKSESPIDDFLNKDLDVLTINDKNEYTTLCSNKNINLIEQDLLATYYASFNMKSNSIF
EEECCCCCHHHHHCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCC
SRDKDVRYALNLAIDKNRIIKDILGGLGVEAKGPFPPSIIPNNKLKGFSHNKSKAKEILS
CCCCCEEEEEEEEECHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
RSDFNRSRDKLNILIRKDEDSLFSKITEYILEDLKNIGIDCIVKEVNSSEYLNLDNILKC
HCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHH
DMAISRWCADSGDPDNFLEPIFNIENVSNISRYDNKLVNEKLEIAKNLINPEKRKKLYEE
HHHHHHHHCCCCCCHHHHHHHHCHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IQEIIVEDVPWIFLYHPKLAIAVQNNILGLNANPLGLFKYEDIIKN
HHHHHHHCCCEEEEECCEEEEEEECCEEECCCCCCEEEEHHHHHCC
>Mature Secondary Structure
MFNFKLKRSSIDKNINSLNEKNIEKPCNIAIYEDNLKVLTNNQRKIVDKLDKKIIETDSV
CCCEEECHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCHHHHHHHHHHHHHCCCHH
TELLIKMTKDISNYVEMEMDSISKVTGEISNYSAIAEEVFSSTENSKQISESTMEVAKEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
NGAALNSIEAMKEIEGSMLYSKTVVKDLSTKALDINNMLDVIKDIANNTNLLSLNASIEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCH
ARAGEAGKGFAVVAHEVKKLAERSMDSVDFIGNNIKEINISIDNAIKAINETMNKVKEGT
HCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHHH
EIANKTMETFNSIISSIKTSTSVSEEINDAITKQIGHLENVINSTEEMNTTSEKLMFIVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LVSLNTQYTKTSLKDLSEVSQNLKYISNNLLHEIEVDSKENNVILNTYIDGRPLYLDPAL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEEEEEECCEEEEECCCC
SYELNSSLLLNNIHIGLLTINSYGEISPGIAKSWYLEKDNLTWIFNLKKGIKFHNGKEVT
CCCCCCCEEEEEEEEEEEEECCCCCCCCCCCCCEEEECCCEEEEEEECCCCEECCCCCCC
SEDVKFSLERLLDPKLDSPNGWLLEIIEGSEDFKEGAAKHVSGIKILDKYRISLTLSYSY
HHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEEEEEEEEEECC
SGFLLNLGLELCGIINKDSINQGDVVGCGPYKISEFNDEGCKLEAFKEYFNGAPYIDIIN
CCHHHHCCHHHHCCCCCCCCCCCCEEECCCEEECCCCCCCCHHHHHHHHHCCCCEEEEEE
INFKSESPIDDFLNKDLDVLTINDKNEYTTLCSNKNINLIEQDLLATYYASFNMKSNSIF
EEECCCCCHHHHHCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCC
SRDKDVRYALNLAIDKNRIIKDILGGLGVEAKGPFPPSIIPNNKLKGFSHNKSKAKEILS
CCCCCEEEEEEEEECHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
RSDFNRSRDKLNILIRKDEDSLFSKITEYILEDLKNIGIDCIVKEVNSSEYLNLDNILKC
HCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHH
DMAISRWCADSGDPDNFLEPIFNIENVSNISRYDNKLVNEKLEIAKNLINPEKRKKLYEE
HHHHHHHHCCCCCCHHHHHHHHCHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IQEIIVEDVPWIFLYHPKLAIAVQNNILGLNANPLGLFKYEDIIKN
HHHHHHHCCCEEEEECCEEEEEEECCEEECCCCCCEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]