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The map label for this gene is helD [H]

Identifier: 170756517

GI number: 170756517

Start: 3629363

End: 3631492

Strand: Reverse

Name: helD [H]

Synonym: CLD_1179

Alternate gene names: 170756517

Gene position: 3631492-3629363 (Counterclockwise)

Preceding gene: 170757175

Following gene: 170754655

Centisome position: 91.75

GC content: 25.77

Gene sequence:

>2130_bases
ATGGATAATAATCAGATAAATAATTCCATGGATAAATATATAGAACTAAGTATGGAAAGAGAATATTTAGATTTTATAAT
AGATAAAGTAAGAAAAGAAACAGGAATATATTTAGATAAAAGAAAAGATATAGTAAAAGATATAGTAGAATATAGGAAAG
AATTTTTAGAAGAAGATAAAAATGATGAAGATAAAGTAGCAGAGTACTTTGATCATGAAAGATACTTAAAAGAAAAGCTT
TATGGTTTTACAGATAAAAAACTAAAAGAGCTCACAGTTTTAGAACAGAATCCTTACTTTGGAAAAGTTAATTTTATAGA
TGAAGGGGATGAAGATTCTATCTATATAGGTAGATACGGATTTTTAGAAACAGGTAATTATAAACCTTTTATTGTAGATT
GGAGAGCTCCTATATGTCAAATATTTTATCAGGGGAAATTAGGAAATATAGCATATGAATCACCAGATGGTAAAATAGAG
GTAGATGTAAAATCTAAAAGGCAATATGTTATCCGTAAGGGTATATTAAAAGGTATGTTTGATTCTGCTTTAGATGTAAA
AGATGAAGTTCTTCAAATGATTTTAAGTGAAAATACCAAAGAAAAATTAAAGGATATAGTTATGACTATACAAGAAGAGC
AAGATAACTTAATTAGACAACCTAAAGACAAAGCTATGATTGTTAATGGAGTTGCAGGTAGTGGTAAGACTACCATTGCT
CTTCATAGAGTAGCATACTTATTATATAATTATAGGAACCAAATACAAGATAAAGTACTAATACTAGGACCTAATAATAT
TTTCGTGGATTATATATCAGAAGTGTTACCGAGTCTAGGTGAAAATGGAGTTAAACAAACTACCTTTAAGGATTTTATAG
AAGACTTGCTACCTACAAATAATTTCCTAGAATATGATAACTATATAGAAAAATTTATAAAAAAAGATAATGAATTTATA
GAAGATATAGCATATAAACAATCTAAAGCATATATGGAAGATTTAGATAGTTTTATGGAAGATCTAGAACGAAACATATT
TATTACAGAAGATGTAATATTGATGGAAGAAGTTGCTATAGATAAAAAAGAAATAGACGAAATGCTTCATTCCTATTATA
AATATATGCCTTTATTTAAAAGAAGTAGGAAGATAAAAAGAATAGTATTTTCTAAAATAAGAGATGTGAGAAACAAAAAA
GTTTATGAAATTCAAAGACAATATGAAGAAAAAATAAAAAAGTTATCAGAGGAAGAACTACAACTAAATAAAAATAATTT
AGAGTTTGAAAGAAAAAATAATATAAGAAACATAGTTAGAAAATCTATGGAGTTAAAGAAATCATTAGTATGGTTAGATA
ATCCACAGGTTTTGGATATATATAATGAGTTTAATAATAACAACAAGCTTACTGTAGATGATATTATAGCTATATTATAT
TTAAGAATAAAATTAGAGGGTTTAAGATATAGGAATGGAATAAAACATATAGTAATAGACGAAGCACAGGATTATTCATT
TTTACAGTTTGTAGTATTAAAAGAACTTACAGATTGTCAATCTATAACTATAGTAGGAGATGTTAATCAAAGAACATTAC
CTTGCAAGGATGAAGTTCCTATGTTATGCTTAGATTCTGTCTTTAATAGAGTCGATGTAGAGTATTTTAATTTAGATAAA
AGTTATAGATCAACAAAAGAGATTATAGAGTACGCTAATAAACATTTAAAGACAAATAAAATTGTTCCTTTGGTGAGAGA
AGGAGACCCTGTAAAAGAAGTGACAGTGAAGAATTCAAGGGAAGCAATAGATAAAGTTAATTATTATTTAAGTTACTTAG
AAAATAAAGAGTATGAAAATATTGCAATTATAACAACTACACTAGAACAGGGGAAAGTTATAGGATCAGAATTAAAAAAG
CAAATGTATATTAATTTAATAGAAAGAGAAGATATAATTTATTCTGGAGGTAAGATAATAATTCCATCTTATTTATCAAA
AGGTTTAGAATTTGATGCTACTATTTTAATATTAGATGATAATAATATAGGAGAAAATTTAAAATATATAATGGCTACAA
GAGCTTTACATGAAATGATAGTTGTACACAAAGAAGGTAAAAAGTTATAA

Upstream 100 bases:

>100_bases
AAATATTAGATAAAAAGGCTGTAGATAAGCTTGTAGTGGATACAAAGGAAACAAGTGATAAATCACCTATAGAAGAATAA
ACCGGAATGGAGAGAGGTTT

Downstream 100 bases:

>100_bases
ACAGTGTGGATAACTTTTTACTAATAATGGGGACTATTTGTACAAAAATATTACATCATAAGTTGTAATTAATGATATTT
AAATAAAATTAATAAAAAGA

Product: putative helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 709; Mature: 709

Protein sequence:

>709_residues
MDNNQINNSMDKYIELSMEREYLDFIIDKVRKETGIYLDKRKDIVKDIVEYRKEFLEEDKNDEDKVAEYFDHERYLKEKL
YGFTDKKLKELTVLEQNPYFGKVNFIDEGDEDSIYIGRYGFLETGNYKPFIVDWRAPICQIFYQGKLGNIAYESPDGKIE
VDVKSKRQYVIRKGILKGMFDSALDVKDEVLQMILSENTKEKLKDIVMTIQEEQDNLIRQPKDKAMIVNGVAGSGKTTIA
LHRVAYLLYNYRNQIQDKVLILGPNNIFVDYISEVLPSLGENGVKQTTFKDFIEDLLPTNNFLEYDNYIEKFIKKDNEFI
EDIAYKQSKAYMEDLDSFMEDLERNIFITEDVILMEEVAIDKKEIDEMLHSYYKYMPLFKRSRKIKRIVFSKIRDVRNKK
VYEIQRQYEEKIKKLSEEELQLNKNNLEFERKNNIRNIVRKSMELKKSLVWLDNPQVLDIYNEFNNNNKLTVDDIIAILY
LRIKLEGLRYRNGIKHIVIDEAQDYSFLQFVVLKELTDCQSITIVGDVNQRTLPCKDEVPMLCLDSVFNRVDVEYFNLDK
SYRSTKEIIEYANKHLKTNKIVPLVREGDPVKEVTVKNSREAIDKVNYYLSYLENKEYENIAIITTTLEQGKVIGSELKK
QMYINLIEREDIIYSGGKIIIPSYLSKGLEFDATILILDDNNIGENLKYIMATRALHEMIVVHKEGKKL

Sequences:

>Translated_709_residues
MDNNQINNSMDKYIELSMEREYLDFIIDKVRKETGIYLDKRKDIVKDIVEYRKEFLEEDKNDEDKVAEYFDHERYLKEKL
YGFTDKKLKELTVLEQNPYFGKVNFIDEGDEDSIYIGRYGFLETGNYKPFIVDWRAPICQIFYQGKLGNIAYESPDGKIE
VDVKSKRQYVIRKGILKGMFDSALDVKDEVLQMILSENTKEKLKDIVMTIQEEQDNLIRQPKDKAMIVNGVAGSGKTTIA
LHRVAYLLYNYRNQIQDKVLILGPNNIFVDYISEVLPSLGENGVKQTTFKDFIEDLLPTNNFLEYDNYIEKFIKKDNEFI
EDIAYKQSKAYMEDLDSFMEDLERNIFITEDVILMEEVAIDKKEIDEMLHSYYKYMPLFKRSRKIKRIVFSKIRDVRNKK
VYEIQRQYEEKIKKLSEEELQLNKNNLEFERKNNIRNIVRKSMELKKSLVWLDNPQVLDIYNEFNNNNKLTVDDIIAILY
LRIKLEGLRYRNGIKHIVIDEAQDYSFLQFVVLKELTDCQSITIVGDVNQRTLPCKDEVPMLCLDSVFNRVDVEYFNLDK
SYRSTKEIIEYANKHLKTNKIVPLVREGDPVKEVTVKNSREAIDKVNYYLSYLENKEYENIAIITTTLEQGKVIGSELKK
QMYINLIEREDIIYSGGKIIIPSYLSKGLEFDATILILDDNNIGENLKYIMATRALHEMIVVHKEGKKL
>Mature_709_residues
MDNNQINNSMDKYIELSMEREYLDFIIDKVRKETGIYLDKRKDIVKDIVEYRKEFLEEDKNDEDKVAEYFDHERYLKEKL
YGFTDKKLKELTVLEQNPYFGKVNFIDEGDEDSIYIGRYGFLETGNYKPFIVDWRAPICQIFYQGKLGNIAYESPDGKIE
VDVKSKRQYVIRKGILKGMFDSALDVKDEVLQMILSENTKEKLKDIVMTIQEEQDNLIRQPKDKAMIVNGVAGSGKTTIA
LHRVAYLLYNYRNQIQDKVLILGPNNIFVDYISEVLPSLGENGVKQTTFKDFIEDLLPTNNFLEYDNYIEKFIKKDNEFI
EDIAYKQSKAYMEDLDSFMEDLERNIFITEDVILMEEVAIDKKEIDEMLHSYYKYMPLFKRSRKIKRIVFSKIRDVRNKK
VYEIQRQYEEKIKKLSEEELQLNKNNLEFERKNNIRNIVRKSMELKKSLVWLDNPQVLDIYNEFNNNNKLTVDDIIAILY
LRIKLEGLRYRNGIKHIVIDEAQDYSFLQFVVLKELTDCQSITIVGDVNQRTLPCKDEVPMLCLDSVFNRVDVEYFNLDK
SYRSTKEIIEYANKHLKTNKIVPLVREGDPVKEVTVKNSREAIDKVNYYLSYLENKEYENIAIITTTLEQGKVIGSELKK
QMYINLIEREDIIYSGGKIIIPSYLSKGLEFDATILILDDNNIGENLKYIMATRALHEMIVVHKEGKKL

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 83625; Mature: 83625

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNNQINNSMDKYIELSMEREYLDFIIDKVRKETGIYLDKRKDIVKDIVEYRKEFLEEDK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHCCC
NDEDKVAEYFDHERYLKEKLYGFTDKKLKELTVLEQNPYFGKVNFIDEGDEDSIYIGRYG
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEECCCCEEEEEECCCCCCCCEEEEEEE
FLETGNYKPFIVDWRAPICQIFYQGKLGNIAYESPDGKIEVDVKSKRQYVIRKGILKGMF
EEECCCCCCEEEECCCHHHHHHHCCCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHHHHH
DSALDVKDEVLQMILSENTKEKLKDIVMTIQEEQDNLIRQPKDKAMIVNGVAGSGKTTIA
HHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHH
LHRVAYLLYNYRNQIQDKVLILGPNNIFVDYISEVLPSLGENGVKQTTFKDFIEDLLPTN
HHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
NFLEYDNYIEKFIKKDNEFIEDIAYKQSKAYMEDLDSFMEDLERNIFITEDVILMEEVAI
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHC
DKKEIDEMLHSYYKYMPLFKRSRKIKRIVFSKIRDVRNKKVYEIQRQYEEKIKKLSEEEL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHH
QLNKNNLEFERKNNIRNIVRKSMELKKSLVWLDNPQVLDIYNEFNNNNKLTVDDIIAILY
HCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEEHHHHHCCCCCEEHHHHHHHHH
LRIKLEGLRYRNGIKHIVIDEAQDYSFLQFVVLKELTDCQSITIVGDVNQRTLPCKDEVP
HHHHHCCHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
MLCLDSVFNRVDVEYFNLDKSYRSTKEIIEYANKHLKTNKIVPLVREGDPVKEVTVKNSR
HHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHCCCCHH
EAIDKVNYYLSYLENKEYENIAIITTTLEQGKVIGSELKKQMYINLIEREDIIYSGGKII
HHHHHHHHHHHHHCCCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHCCCEEECCCCEE
IPSYLSKGLEFDATILILDDNNIGENLKYIMATRALHEMIVVHKEGKKL
ECHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHEECCCCCC
>Mature Secondary Structure
MDNNQINNSMDKYIELSMEREYLDFIIDKVRKETGIYLDKRKDIVKDIVEYRKEFLEEDK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHCCC
NDEDKVAEYFDHERYLKEKLYGFTDKKLKELTVLEQNPYFGKVNFIDEGDEDSIYIGRYG
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEECCCCEEEEEECCCCCCCCEEEEEEE
FLETGNYKPFIVDWRAPICQIFYQGKLGNIAYESPDGKIEVDVKSKRQYVIRKGILKGMF
EEECCCCCCEEEECCCHHHHHHHCCCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHHHHH
DSALDVKDEVLQMILSENTKEKLKDIVMTIQEEQDNLIRQPKDKAMIVNGVAGSGKTTIA
HHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHH
LHRVAYLLYNYRNQIQDKVLILGPNNIFVDYISEVLPSLGENGVKQTTFKDFIEDLLPTN
HHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
NFLEYDNYIEKFIKKDNEFIEDIAYKQSKAYMEDLDSFMEDLERNIFITEDVILMEEVAI
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHC
DKKEIDEMLHSYYKYMPLFKRSRKIKRIVFSKIRDVRNKKVYEIQRQYEEKIKKLSEEEL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHH
QLNKNNLEFERKNNIRNIVRKSMELKKSLVWLDNPQVLDIYNEFNNNNKLTVDDIIAILY
HCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEEHHHHHCCCCCEEHHHHHHHHH
LRIKLEGLRYRNGIKHIVIDEAQDYSFLQFVVLKELTDCQSITIVGDVNQRTLPCKDEVP
HHHHHCCHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
MLCLDSVFNRVDVEYFNLDKSYRSTKEIIEYANKHLKTNKIVPLVREGDPVKEVTVKNSR
HHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHCCCCHH
EAIDKVNYYLSYLENKEYENIAIITTTLEQGKVIGSELKKQMYINLIEREDIIYSGGKII
HHHHHHHHHHHHHCCCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHCCCEEECCCCEE
IPSYLSKGLEFDATILILDDNNIGENLKYIMATRALHEMIVVHKEGKKL
ECHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]