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The map label for this gene is cssR [H]

Identifier: 170756225

GI number: 170756225

Start: 374941

End: 375615

Strand: Direct

Name: cssR [H]

Synonym: CLD_0455

Alternate gene names: 170756225

Gene position: 374941-375615 (Clockwise)

Preceding gene: 170755969

Following gene: 170757281

Centisome position: 9.47

GC content: 28.44

Gene sequence:

>675_bases
ATGGGAAGAAAAGTCTATCTTGTTGAAGATGAAAAAAGTCTGAATATATTATTAGAAAAGTATCTACAACGTGAAGGGTA
TGAAGTAACTACTTTTTTTAATGGAAGCTCTGCAATAGAGAGAATAAAAGATGTTCCAGATATTTGGATATTAGATATAA
TGTTACCTGATATAGATGGATATCAAATAATTAAAGCTGTAAAAGAAAACAATAAAAATACTCCAGTTATTTTTATGTCT
GCGAGGAATGAGGAACTGGATAGAGTGGTGGGATTAGAATTAGGAAGTGATGATTATTTATCAAAGCCATTTTTACCTAG
AGAGCTTATAATAAGAACTAATAAACTTATGGAAAGAATTTATGGGAAAAGTAATAATTCTATGGACATAATTACAAATA
TTGGAGAGTACAAAATAAGTAAAAGACAAAGAGCTGTTTTTTTCGGAGAAAAAGAAATTCAACTAACAAACAAAGAGTTT
GAACTATTAAATTTTTTTGTAGAGAATAGAAACAATGTTATATCTAGAGAACAAATTTTAATTAGTATTTGGGGAGAGGA
TTATTTCGGATCTGATAGAGTTATTGATGATACAATTAGGAGATTGCGCAAAAAGATGGATAAGTTAGATCTTGAAACTG
TATATGGATATGGTTATAAATTGGTGGTTAAATGA

Upstream 100 bases:

>100_bases
TTACTAATGTCATAGATGTAAAGCAAATGGCGACTGTAAAATTAAAAATAAGGTTTAATGGATAAACTAAAATACTGGAT
TATATTTTGAGGTGATAAAG

Downstream 100 bases:

>100_bases
TGAGGAGATTAAGATTTAAATCGTTAACAATGAGGATATGGACAACATTCACTGCTATAATTTTAATAATAATATGTAGT
ATTTCATTTTTATATTTAGT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MGRKVYLVEDEKSLNILLEKYLQREGYEVTTFFNGSSAIERIKDVPDIWILDIMLPDIDGYQIIKAVKENNKNTPVIFMS
ARNEELDRVVGLELGSDDYLSKPFLPRELIIRTNKLMERIYGKSNNSMDIITNIGEYKISKRQRAVFFGEKEIQLTNKEF
ELLNFFVENRNNVISREQILISIWGEDYFGSDRVIDDTIRRLRKKMDKLDLETVYGYGYKLVVK

Sequences:

>Translated_224_residues
MGRKVYLVEDEKSLNILLEKYLQREGYEVTTFFNGSSAIERIKDVPDIWILDIMLPDIDGYQIIKAVKENNKNTPVIFMS
ARNEELDRVVGLELGSDDYLSKPFLPRELIIRTNKLMERIYGKSNNSMDIITNIGEYKISKRQRAVFFGEKEIQLTNKEF
ELLNFFVENRNNVISREQILISIWGEDYFGSDRVIDDTIRRLRKKMDKLDLETVYGYGYKLVVK
>Mature_223_residues
GRKVYLVEDEKSLNILLEKYLQREGYEVTTFFNGSSAIERIKDVPDIWILDIMLPDIDGYQIIKAVKENNKNTPVIFMSA
RNEELDRVVGLELGSDDYLSKPFLPRELIIRTNKLMERIYGKSNNSMDIITNIGEYKISKRQRAVFFGEKEIQLTNKEFE
LLNFFVENRNNVISREQILISIWGEDYFGSDRVIDDTIRRLRKKMDKLDLETVYGYGYKLVVK

Specific function: Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=35.4260089686099, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=34.9137931034483, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=32.1739130434783, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=32.4561403508772, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI2367329, Length=235, Percent_Identity=36.1702127659575, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=34.7826086956522, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=32.4561403508772, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=33.1858407079646, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=30.5936073059361, Blast_Score=110, Evalue=5e-26,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=30.8370044052863, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=30.3030303030303, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=30.7692307692308, Blast_Score=102, Evalue=1e-23,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=27.6018099547511, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI145693140, Length=211, Percent_Identity=28.9099526066351, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1790299, Length=101, Percent_Identity=35.6435643564356, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788550, Length=102, Percent_Identity=32.3529411764706, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26342; Mature: 26211

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRKVYLVEDEKSLNILLEKYLQREGYEVTTFFNGSSAIERIKDVPDIWILDIMLPDIDG
CCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCEEEEEEECCCCCH
YQIIKAVKENNKNTPVIFMSARNEELDRVVGLELGSDDYLSKPFLPRELIIRTNKLMERI
HHHHHHHHHCCCCCCEEEEECCCCCHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
YGKSNNSMDIITNIGEYKISKRQRAVFFGEKEIQLTNKEFELLNFFVENRNNVISREQIL
HCCCCCCEEEEECCCHHHHCCCCEEEEECCCEEEEECHHHHHHHHHHHCCCCEECCEEEE
ISIWGEDYFGSDRVIDDTIRRLRKKMDKLDLETVYGYGYKLVVK
EEECCCCCCCCCCCHHHHHHHHHHHHHHCCHHEEECCCEEEEEC
>Mature Secondary Structure 
GRKVYLVEDEKSLNILLEKYLQREGYEVTTFFNGSSAIERIKDVPDIWILDIMLPDIDG
CCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCEEEEEEECCCCCH
YQIIKAVKENNKNTPVIFMSARNEELDRVVGLELGSDDYLSKPFLPRELIIRTNKLMERI
HHHHHHHHHCCCCCCEEEEECCCCCHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
YGKSNNSMDIITNIGEYKISKRQRAVFFGEKEIQLTNKEFELLNFFVENRNNVISREQIL
HCCCCCCEEEEECCCHHHHCCCCEEEEECCCEEEEECHHHHHHHHHHHCCCCEECCEEEE
ISIWGEDYFGSDRVIDDTIRRLRKKMDKLDLETVYGYGYKLVVK
EEECCCCCCCCCCCHHHHHHHHHHHHHHCCHHEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9639930; 9384377; 11555295 [H]