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The map label for this gene is murB

Identifier: 170756034

GI number: 170756034

Start: 3686192

End: 3687112

Strand: Reverse

Name: murB

Synonym: CLD_1130

Alternate gene names: 170756034

Gene position: 3687112-3686192 (Counterclockwise)

Preceding gene: 170755437

Following gene: 170757064

Centisome position: 93.15

GC content: 29.42

Gene sequence:

>921_bases
ATGAACCAATATAAAAATTTTATCATGCAGTTTGAAGATATAGTTGGAAATAATAATGTTTTAATAGATGAGCCAATGAA
AAAACATACTTCATTTAAAGTTGGAGGACCAGCAGATTTATTAATTACACCTACAACTTTAGAACAAGTAAAGGATAGTA
TTATATTATGTAGAAATAATAGTATTCCTTATTATATAATAGGAAATGGGTCAAATTTATTAGTAAGAGATGGTGGAATA
AGAGGAGTAGTAATTAAGTTTTTAAAATTAGGTGATATAAAAGTAGAAGGAGATAGAGTAATAGCTCAAAGTGGAGCTCC
TTTAACTAATATTTGTAATGAAGCCTTAAAAAGTAATTTAGGTGGACTAGAGTTTGCTTGTGGTATACCAGGTAGCGTAG
GCGGAGCAGTTACAATGAATGCTGGTGCTTATAATGGAGAAATATCTCAAGTTATAGAAAGTGCTAAAGTTATAGACAAG
GATGGAAATGTATTTTTATTAAACAAAGAACAATTAGATTTGGGATATAGAATGAGTGCTATTCAAAAGTATCACTATAT
TGTTTTAGAAGTAACCTTTAAATTACATAATAGTGAATATGATACTATAAAAAATAGAATAATGGATTTAAATAGAAGAA
GAATAGAAAAACAACCTTTAGAATATCCATCAGCAGGTAGTACTTTTAAAAGGCCAGAAGGACATTTCGCAGCAAAACTT
ATAGAAGATACAGGTTTAAAGGGTGAATCTATAGGAGGGGCTCAAGTTTCAGAAAAACATTCTGGCTTTATAATAAATAA
GGGAGGAGCTACTGCAGGAGATATATTAAATCTTATAGAATTTGTACAAAATAAGGTTATGGAAAAGTTTCAAGTAGATC
TTCATACAGAAGTTAGAATAATTGGAGAGGAAAACAATTAG

Upstream 100 bases:

>100_bases
AAGGGAAGTTAAAGGATTTAAATCTTGATTAAGGGCTAAGCATACATTATACTAATAAGGGTATTTAATTTAGTAATAAA
AAAATCAAGGAGAATGTGTT

Downstream 100 bases:

>100_bases
AATATAATAAATAAGGGAAGTCTTAACAAATGACTTCCCTAGTTTATTGTTAAATAGGTATATGATATAATTAAATAAAA
CATAAAATAATATTCCTTAA

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNQYKNFIMQFEDIVGNNNVLIDEPMKKHTSFKVGGPADLLITPTTLEQVKDSIILCRNNSIPYYIIGNGSNLLVRDGGI
RGVVIKFLKLGDIKVEGDRVIAQSGAPLTNICNEALKSNLGGLEFACGIPGSVGGAVTMNAGAYNGEISQVIESAKVIDK
DGNVFLLNKEQLDLGYRMSAIQKYHYIVLEVTFKLHNSEYDTIKNRIMDLNRRRIEKQPLEYPSAGSTFKRPEGHFAAKL
IEDTGLKGESIGGAQVSEKHSGFIINKGGATAGDILNLIEFVQNKVMEKFQVDLHTEVRIIGEENN

Sequences:

>Translated_306_residues
MNQYKNFIMQFEDIVGNNNVLIDEPMKKHTSFKVGGPADLLITPTTLEQVKDSIILCRNNSIPYYIIGNGSNLLVRDGGI
RGVVIKFLKLGDIKVEGDRVIAQSGAPLTNICNEALKSNLGGLEFACGIPGSVGGAVTMNAGAYNGEISQVIESAKVIDK
DGNVFLLNKEQLDLGYRMSAIQKYHYIVLEVTFKLHNSEYDTIKNRIMDLNRRRIEKQPLEYPSAGSTFKRPEGHFAAKL
IEDTGLKGESIGGAQVSEKHSGFIINKGGATAGDILNLIEFVQNKVMEKFQVDLHTEVRIIGEENN
>Mature_306_residues
MNQYKNFIMQFEDIVGNNNVLIDEPMKKHTSFKVGGPADLLITPTTLEQVKDSIILCRNNSIPYYIIGNGSNLLVRDGGI
RGVVIKFLKLGDIKVEGDRVIAQSGAPLTNICNEALKSNLGGLEFACGIPGSVGGAVTMNAGAYNGEISQVIESAKVIDK
DGNVFLLNKEQLDLGYRMSAIQKYHYIVLEVTFKLHNSEYDTIKNRIMDLNRRRIEKQPLEYPSAGSTFKRPEGHFAAKL
IEDTGLKGESIGGAQVSEKHSGFIINKGGATAGDILNLIEFVQNKVMEKFQVDLHTEVRIIGEENN

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 33660; Mature: 33660

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQYKNFIMQFEDIVGNNNVLIDEPMKKHTSFKVGGPADLLITPTTLEQVKDSIILCRNN
CCHHHHHHHHHHHHCCCCCEEECCCHHHCCCEECCCCCEEEEECHHHHHHCCCEEEEECC
SIPYYIIGNGSNLLVRDGGIRGVVIKFLKLGDIKVEGDRVIAQSGAPLTNICNEALKSNL
CCCEEEEECCCEEEEECCCCHHHHHHHHHHCCEEECCCEEEECCCCCHHHHHHHHHHCCC
GGLEFACGIPGSVGGAVTMNAGAYNGEISQVIESAKVIDKDGNVFLLNKEQLDLGYRMSA
CCEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHEECCCCEEEEEHHCCCCCHHHHH
IQKYHYIVLEVTFKLHNSEYDTIKNRIMDLNRRRIEKQPLEYPSAGSTFKRPEGHFAAKL
HHHEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
IEDTGLKGESIGGAQVSEKHSGFIINKGGATAGDILNLIEFVQNKVMEKFQVDLHTEVRI
HHHCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEE
IGEENN
EECCCC
>Mature Secondary Structure
MNQYKNFIMQFEDIVGNNNVLIDEPMKKHTSFKVGGPADLLITPTTLEQVKDSIILCRNN
CCHHHHHHHHHHHHCCCCCEEECCCHHHCCCEECCCCCEEEEECHHHHHHCCCEEEEECC
SIPYYIIGNGSNLLVRDGGIRGVVIKFLKLGDIKVEGDRVIAQSGAPLTNICNEALKSNL
CCCEEEEECCCEEEEECCCCHHHHHHHHHHCCEEECCCEEEECCCCCHHHHHHHHHHCCC
GGLEFACGIPGSVGGAVTMNAGAYNGEISQVIESAKVIDKDGNVFLLNKEQLDLGYRMSA
CCEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHEECCCCEEEEEHHCCCCCHHHHH
IQKYHYIVLEVTFKLHNSEYDTIKNRIMDLNRRRIEKQPLEYPSAGSTFKRPEGHFAAKL
HHHEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
IEDTGLKGESIGGAQVSEKHSGFIINKGGATAGDILNLIEFVQNKVMEKFQVDLHTEVRI
HHHCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEE
IGEENN
EECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA