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The map label for this gene is ftsW [H]

Identifier: 170755973

GI number: 170755973

Start: 3692985

End: 3694214

Strand: Reverse

Name: ftsW [H]

Synonym: CLD_1124

Alternate gene names: 170755973

Gene position: 3694214-3692985 (Counterclockwise)

Preceding gene: 170754919

Following gene: 170757154

Centisome position: 93.33

GC content: 30.89

Gene sequence:

>1230_bases
ATGAAATGTGGGATGGTGAGAAGGATGGACTCTATAAAGGGTGAAAAGAGACTTTTAAGATATACTTATTTTTTATGTAT
AGTATGCTTTTTGAACTTAGCTATATTAAAACAACCTTTTGATAAAGGAGCTATGATAATAGCTGCAGTTACTTGTTTAT
TAATAGGATATTCCTATTTTATAATAAGAAAATTTTTCTCCGATGGAGATAAATATATGTTTATTTTTTCTAGTATACTA
TCAGTTATAGGCATAGTTATGCTTTACAGAATAGATGTAAGTACTTCCATAAAGCAGATAATATGGTTTGCTATTGGGGT
TACAGTTTTTATATTAATGGTAGTTTTACTGCCAGATCTAAAAAGGTTTGATAAATACAAGTATTTATTTTTAATAATTA
CTATTTTATTTATGGGTCTTGGAACTTTATTTGGGAAAGAAACATATGGAGCAAAGAACTGGGTAAATATAGGTGGTATT
GCTTTTCAGCCATCAGAGTTTGGAAAAATATTTTTAGTAGCTTATTTAGCTGCTTCATTAAAGGATTATGATGGTAAATT
TATAAAGTTAATAGAGCCAGCTGTAGTAGTTATGATGTGTTTAGGCTTTATGGTATTGCAAAGAGACTTGGGTTCCGCTT
TAATATTTTTTGGTATATCCATAACTATGTTGTATATAGCTACTTCTAAATTAAAATATGTATTAACTTGTTTAGGGTTA
TTTGGCGCAGGATCAGTTATATCTTATAAATTGTTTGATCATGTTCAGACAAGGGTGCTTATATGGAAAAATCCATGGCC
TTATGCTAGTGGGAAAAGCTATCAGATAGTCCAATCTATGCTTTCTATAGCATCTGGAGGATTAAGTGGAACTGGATTAG
GACTTGGACATCCAGAATATGTGCCAGTAAATACTACGGATTTTATATATGCAGTTATATGTGAAGAATTAGGAATACTA
ATGGGGTTTGCCATAATAATATTTTATTTTCTTTTATTTTATAGAGGTATGAGAGCAGCGGTTCATGCGGAAAATAACTT
TTCAAGACTTTTAGCAGTAGGGTATAGCGCTATGATAGCTTCTCAAGTATTAGTAATAGTAGGTGGAGTTATAAATATGA
TTCCTCTTACTGGTATAACATTACCTCTAGTAAGCCGTGGAGGAAGTTCCATGATGAGTATTTATATTTGTTTAGGTATA
TTACAAAAGATATCAGAAGAGGGTAGATAA

Upstream 100 bases:

>100_bases
TTAAATAATAAAAATATTACAGGAAAAAATCAGTTATCACCGGGAGATTTAATCAAAATAGGTGGTACGGTTTTTAAGGT
AATAGGATAAGATAAAATCC

Downstream 100 bases:

>100_bases
AATTATGAAGGATATTTCAAATAATATAAAAAAAGTTTTATTAGTTTTTTTAATATGCTTTATGGGACTTATAACCTATA
TAACCTATTTTGAAATAGTA

Product: cell cycle protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MKCGMVRRMDSIKGEKRLLRYTYFLCIVCFLNLAILKQPFDKGAMIIAAVTCLLIGYSYFIIRKFFSDGDKYMFIFSSIL
SVIGIVMLYRIDVSTSIKQIIWFAIGVTVFILMVVLLPDLKRFDKYKYLFLIITILFMGLGTLFGKETYGAKNWVNIGGI
AFQPSEFGKIFLVAYLAASLKDYDGKFIKLIEPAVVVMMCLGFMVLQRDLGSALIFFGISITMLYIATSKLKYVLTCLGL
FGAGSVISYKLFDHVQTRVLIWKNPWPYASGKSYQIVQSMLSIASGGLSGTGLGLGHPEYVPVNTTDFIYAVICEELGIL
MGFAIIIFYFLLFYRGMRAAVHAENNFSRLLAVGYSAMIASQVLVIVGGVINMIPLTGITLPLVSRGGSSMMSIYICLGI
LQKISEEGR

Sequences:

>Translated_409_residues
MKCGMVRRMDSIKGEKRLLRYTYFLCIVCFLNLAILKQPFDKGAMIIAAVTCLLIGYSYFIIRKFFSDGDKYMFIFSSIL
SVIGIVMLYRIDVSTSIKQIIWFAIGVTVFILMVVLLPDLKRFDKYKYLFLIITILFMGLGTLFGKETYGAKNWVNIGGI
AFQPSEFGKIFLVAYLAASLKDYDGKFIKLIEPAVVVMMCLGFMVLQRDLGSALIFFGISITMLYIATSKLKYVLTCLGL
FGAGSVISYKLFDHVQTRVLIWKNPWPYASGKSYQIVQSMLSIASGGLSGTGLGLGHPEYVPVNTTDFIYAVICEELGIL
MGFAIIIFYFLLFYRGMRAAVHAENNFSRLLAVGYSAMIASQVLVIVGGVINMIPLTGITLPLVSRGGSSMMSIYICLGI
LQKISEEGR
>Mature_409_residues
MKCGMVRRMDSIKGEKRLLRYTYFLCIVCFLNLAILKQPFDKGAMIIAAVTCLLIGYSYFIIRKFFSDGDKYMFIFSSIL
SVIGIVMLYRIDVSTSIKQIIWFAIGVTVFILMVVLLPDLKRFDKYKYLFLIITILFMGLGTLFGKETYGAKNWVNIGGI
AFQPSEFGKIFLVAYLAASLKDYDGKFIKLIEPAVVVMMCLGFMVLQRDLGSALIFFGISITMLYIATSKLKYVLTCLGL
FGAGSVISYKLFDHVQTRVLIWKNPWPYASGKSYQIVQSMLSIASGGLSGTGLGLGHPEYVPVNTTDFIYAVICEELGIL
MGFAIIIFYFLLFYRGMRAAVHAENNFSRLLAVGYSAMIASQVLVIVGGVINMIPLTGITLPLVSRGGSSMMSIYICLGI
LQKISEEGR

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=314, Percent_Identity=30.2547770700637, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1786853, Length=336, Percent_Identity=28.5714285714286, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 45545; Mature: 45545

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]