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The map label for this gene is resD [H]

Identifier: 170755428

GI number: 170755428

Start: 332795

End: 333472

Strand: Direct

Name: resD [H]

Synonym: CLD_0494

Alternate gene names: 170755428

Gene position: 332795-333472 (Clockwise)

Preceding gene: 170754634

Following gene: 170756447

Centisome position: 8.41

GC content: 26.55

Gene sequence:

>678_bases
ATGAAAGAAACTATACTTGTTATAGATGATGAAGTTAAGATAATAGAAGTTATAAAATTGTATTTAGAAAATGAGGGATA
TACTGTGATACAGGCTACAAGTGGGATTGAGGCATTGAAAAAGCAAAGTGAGTTTAATCCTAATCTATTAATATTAGATT
TAATGTTACCTGATATATCAGGTGAAAATGTCTGTGAGCGCATAAGGAAAGAATCTGAAGTACCAATAATTATGCTAACT
GCTAAATCGAGTGAAGATAGTATACTAAATGGATATTCAATTGGAAGTGATGACTATATAACAAAACCATTTAGTCCAAA
ACAATTAGTAGCGAAGGTTAATGCAGTTTTAAAAAGAGTTAAGGGAAATCAATGTGAAAACTTAATTTTTAATAATGAAT
TAATCATAGATATTGTTAATAAGAAAGTAGAATACAATAACAAAGAAATTATATTAACTGCTTCGGAATATAAAATATTA
TCTATACTAGCTAGAAATCCTAATAAAATATTTTCAAGGGAAGAGTTAATGGATTATATAAGTAGAGATAATATTTGTAT
CTATGATAGAATAATTGATACTCATATAAAAAATATAAGGGCTAAACTAGATCAAGATAGTAAAAATCCAACCTATATAA
AAACTATTCGTGGTATGGGATATAGGTTCAATGTTTAA

Upstream 100 bases:

>100_bases
AAATTTAGTGTATGATCATGTAGGAATCATTGATAAAGAAATACTTGATGAAAATATAAATAAGATAATTAATTAAGTAC
CCATATGGAGGTATAATTTT

Downstream 100 bases:

>100_bases
TAAATTAAGATATAGAGTAAGCTTGATTTTTATATTATTTTCATTGAGTATCATATTTTTAGCAAACATAGTCAACCATT
ATTGTATTGAAAAGAAGTTT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKETILVIDDEVKIIEVIKLYLENEGYTVIQATSGIEALKKQSEFNPNLLILDLMLPDISGENVCERIRKESEVPIIMLT
AKSSEDSILNGYSIGSDDYITKPFSPKQLVAKVNAVLKRVKGNQCENLIFNNELIIDIVNKKVEYNNKEIILTASEYKIL
SILARNPNKIFSREELMDYISRDNICIYDRIIDTHIKNIRAKLDQDSKNPTYIKTIRGMGYRFNV

Sequences:

>Translated_225_residues
MKETILVIDDEVKIIEVIKLYLENEGYTVIQATSGIEALKKQSEFNPNLLILDLMLPDISGENVCERIRKESEVPIIMLT
AKSSEDSILNGYSIGSDDYITKPFSPKQLVAKVNAVLKRVKGNQCENLIFNNELIIDIVNKKVEYNNKEIILTASEYKIL
SILARNPNKIFSREELMDYISRDNICIYDRIIDTHIKNIRAKLDQDSKNPTYIKTIRGMGYRFNV
>Mature_225_residues
MKETILVIDDEVKIIEVIKLYLENEGYTVIQATSGIEALKKQSEFNPNLLILDLMLPDISGENVCERIRKESEVPIIMLT
AKSSEDSILNGYSIGSDDYITKPFSPKQLVAKVNAVLKRVKGNQCENLIFNNELIIDIVNKKVEYNNKEIILTASEYKIL
SILARNPNKIFSREELMDYISRDNICIYDRIIDTHIKNIRAKLDQDSKNPTYIKTIRGMGYRFNV

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=34.3612334801762, Blast_Score=167, Evalue=6e-43,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=36.9369369369369, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=35.1351351351351, Blast_Score=154, Evalue=3e-39,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=33.6244541484716, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=29.0909090909091, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=32.5991189427313, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=32.4561403508772, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=30.1801801801802, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=32.4200913242009, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=30.7339449541284, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=31.0810810810811, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=26.1467889908257, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=30.7359307359307, Blast_Score=98, Evalue=3e-22,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=29.004329004329, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1790299, Length=138, Percent_Identity=26.8115942028986, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25822; Mature: 25822

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKETILVIDDEVKIIEVIKLYLENEGYTVIQATSGIEALKKQSEFNPNLLILDLMLPDIS
CCCEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCEEEEEEECCCCC
GENVCERIRKESEVPIIMLTAKSSEDSILNGYSIGSDDYITKPFSPKQLVAKVNAVLKRV
CHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCCCCCCEECCCCHHHHHHHHHHHHHHH
KGNQCENLIFNNELIIDIVNKKVEYNNKEIILTASEYKILSILARNPNKIFSREELMDYI
CCCCCCEEEECCEEEEEEECCEEECCCCEEEEEECCCEEEEEEECCCHHHCCHHHHHHHH
SRDNICIYDRIIDTHIKNIRAKLDQDSKNPTYIKTIRGMGYRFNV
CCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEECC
>Mature Secondary Structure
MKETILVIDDEVKIIEVIKLYLENEGYTVIQATSGIEALKKQSEFNPNLLILDLMLPDIS
CCCEEEEEECCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCEEEEEEECCCCC
GENVCERIRKESEVPIIMLTAKSSEDSILNGYSIGSDDYITKPFSPKQLVAKVNAVLKRV
CHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCCCCCCEECCCCHHHHHHHHHHHHHHH
KGNQCENLIFNNELIIDIVNKKVEYNNKEIILTASEYKILSILARNPNKIFSREELMDYI
CCCCCCEEEECCEEEEEEECCEEECCCCEEEEEECCCEEEEEEECCCHHHCCHHHHHHHH
SRDNICIYDRIIDTHIKNIRAKLDQDSKNPTYIKTIRGMGYRFNV
CCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]