Click here to switch to the map view.

The map label for this gene is lrgA [H]

Identifier: 170754934

GI number: 170754934

Start: 404985

End: 405341

Strand: Direct

Name: lrgA [H]

Synonym: CLD_0428

Alternate gene names: 170754934

Gene position: 404985-405341 (Clockwise)

Preceding gene: 170756003

Following gene: 170757151

Centisome position: 10.23

GC content: 29.13

Gene sequence:

>357_bases
TTGAGATTATTAAGACAGTTAGGAATAATTTTACTAATTTGCCTACTAGGTGAAGCCATACATGACTTCTTTAAGTTACC
TATACCAGGAAATGTTATAGGGATGATACTATTATTTCTATGCTTATCCTCAGGTATAATAAAATTAACTAAAATAAATT
ACATAAGTAAATTCTTACTTGATCATTTAGCTTTTTTCTTTGTACCGGCGGGAGTAGGAATTTTATCCTGTATGCCTATG
CTAAAAGGTAAATGGTTAGCATTTTTAGGAGTATGCTTAATAACAAGTATTATTATAATAGTTGTTACGGGTTGGACTAT
TCAACTATATATAAAATTAACAAGTAAGGAGGTGTAA

Upstream 100 bases:

>100_bases
TAAAAATTTCAACTTTTATTTTACTATGGCATTTATAATGAAAAAGTAATAAAATAAATACTGTCGTTTAAAACTTAATA
TTTAGAAAAGAGGTGTTACC

Downstream 100 bases:

>100_bases
GAATGATCCAAGATATTTTAAATTCCCCTGTTTTCGGAATCTTATTATCAATAATAGGTTTTGAAATAGGACTTTACATA
TATAGAAAAACAAAGATAGC

Product: lrgA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MRLLRQLGIILLICLLGEAIHDFFKLPIPGNVIGMILLFLCLSSGIIKLTKINYISKFLLDHLAFFFVPAGVGILSCMPM
LKGKWLAFLGVCLITSIIIIVVTGWTIQLYIKLTSKEV

Sequences:

>Translated_118_residues
MRLLRQLGIILLICLLGEAIHDFFKLPIPGNVIGMILLFLCLSSGIIKLTKINYISKFLLDHLAFFFVPAGVGILSCMPM
LKGKWLAFLGVCLITSIIIIVVTGWTIQLYIKLTSKEV
>Mature_118_residues
MRLLRQLGIILLICLLGEAIHDFFKLPIPGNVIGMILLFLCLSSGIIKLTKINYISKFLLDHLAFFFVPAGVGILSCMPM
LKGKWLAFLGVCLITSIIIIVVTGWTIQLYIKLTSKEV

Specific function: Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like proteins CidA and/or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in p

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. LrgA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 13135; Mature: 13135

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLRQLGIILLICLLGEAIHDFFKLPIPGNVIGMILLFLCLSSGIIKLTKINYISKFLL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
DHLAFFFVPAGVGILSCMPMLKGKWLAFLGVCLITSIIIIVVTGWTIQLYIKLTSKEV
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCC
>Mature Secondary Structure
MRLLRQLGIILLICLLGEAIHDFFKLPIPGNVIGMILLFLCLSSGIIKLTKINYISKFLL
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
DHLAFFFVPAGVGILSCMPMLKGKWLAFLGVCLITSIIIIVVTGWTIQLYIKLTSKEV
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA