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The map label for this gene is trxB [H]

Identifier: 170754359

GI number: 170754359

Start: 3744602

End: 3745465

Strand: Reverse

Name: trxB [H]

Synonym: CLD_1072

Alternate gene names: 170754359

Gene position: 3745465-3744602 (Counterclockwise)

Preceding gene: 170754340

Following gene: 170757775

Centisome position: 94.62

GC content: 30.67

Gene sequence:

>864_bases
ATGGGGAAAAGATATGATATAGCTATAATAGGTAGCGGACCTGCAGGGTTGGAAGCAGCCATAAATGCTAAAATAAGAAA
TAAGGATATAATAATATTTGGTAATAAGGAGTTAAGTTCAAAACTTGTGAAGGCTCCTAAAATAAATAATTATCTTGGTT
TTTATGATATTTCAGGTAATGAGCTAAAAGATAAATTTATAGATCATATAGATAAGATGGGAATAGAAATAACTTTTGAG
AGAATAAATAATGTTTATGCTATGGGAGAATATTTTGCTCTAATGGTTAATGAAAAAATGTATGAAGCTAAAACAGTTAT
ATTAGCTACTGGAGTAGAGTATGGGAAAGCATTAAAAGGTGAAGAGGAATTTTTAGGGAAAGGTGTAGGATATTGTGCTA
CTTGTGATGCACCACTTTATAAAAATAAGACAGTTGCCATAATAGGATATAATAAAGAAGCTGAGGAAGAAGCTAATTTT
GTAAGCGAATTAGCATCAAGACTTTATTATATTCCTATGTACAGATCAGATTATGAATTAAGTGAAAAAGTGGAAGTTAT
TAATGATAAACCTATAGAAATAGTAGGAAAACAACATGTGGAAAAATTAATTCTTAAAGATTCAGAAATAGAAGCAGATG
GTATTTTTGTTTTAAAAGATAGTATATCTCCCGCACAATTAGTACCGGGCTTAGAAATGGAAGATGAACATATAAAGGTT
GATAGGAAAATGAAAACTAATATATCAGGATGCTTTGCTGCAGGGGATTGTACTGGTAAACCATATCAATATATAAAATC
TGCAGGAGAAGGTCAAATTGCAGCATTAAGCGCAGTTTCTTATTTAGATAAACAGAGTTCTTAG

Upstream 100 bases:

>100_bases
AAGCTATAAAATCAGCAGTAGAAAAGCATATTTAATATAAAATAAATTGAGAATAGCATTAATGTTATTCTCAATTTTAC
ATTTTTTAGGAGGAGATATT

Downstream 100 bases:

>100_bases
CTTTAGAGGGAATTTTTACTCCCACTAAAGCTTATTAACAGAATTCTTAGGAGTTCTACTCCTTAGAAGTCGTTATCCTT
TAGGGGAAATCGTTATCCAG

Product: pyridine nucleotide-disulfide family oxidoreductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MGKRYDIAIIGSGPAGLEAAINAKIRNKDIIIFGNKELSSKLVKAPKINNYLGFYDISGNELKDKFIDHIDKMGIEITFE
RINNVYAMGEYFALMVNEKMYEAKTVILATGVEYGKALKGEEEFLGKGVGYCATCDAPLYKNKTVAIIGYNKEAEEEANF
VSELASRLYYIPMYRSDYELSEKVEVINDKPIEIVGKQHVEKLILKDSEIEADGIFVLKDSISPAQLVPGLEMEDEHIKV
DRKMKTNISGCFAAGDCTGKPYQYIKSAGEGQIAALSAVSYLDKQSS

Sequences:

>Translated_287_residues
MGKRYDIAIIGSGPAGLEAAINAKIRNKDIIIFGNKELSSKLVKAPKINNYLGFYDISGNELKDKFIDHIDKMGIEITFE
RINNVYAMGEYFALMVNEKMYEAKTVILATGVEYGKALKGEEEFLGKGVGYCATCDAPLYKNKTVAIIGYNKEAEEEANF
VSELASRLYYIPMYRSDYELSEKVEVINDKPIEIVGKQHVEKLILKDSEIEADGIFVLKDSISPAQLVPGLEMEDEHIKV
DRKMKTNISGCFAAGDCTGKPYQYIKSAGEGQIAALSAVSYLDKQSS
>Mature_286_residues
GKRYDIAIIGSGPAGLEAAINAKIRNKDIIIFGNKELSSKLVKAPKINNYLGFYDISGNELKDKFIDHIDKMGIEITFER
INNVYAMGEYFALMVNEKMYEAKTVILATGVEYGKALKGEEEFLGKGVGYCATCDAPLYKNKTVAIIGYNKEAEEEANFV
SELASRLYYIPMYRSDYELSEKVEVINDKPIEIVGKQHVEKLILKDSEIEADGIFVLKDSISPAQLVPGLEMEDEHIKVD
RKMKTNISGCFAAGDCTGKPYQYIKSAGEGQIAALSAVSYLDKQSS

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=313, Percent_Identity=33.2268370607029, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI87081763, Length=261, Percent_Identity=29.1187739463602, Blast_Score=97, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6320560, Length=312, Percent_Identity=32.6923076923077, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6321898, Length=316, Percent_Identity=31.0126582278481, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 31823; Mature: 31692

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKRYDIAIIGSGPAGLEAAINAKIRNKDIIIFGNKELSSKLVKAPKINNYLGFYDISGN
CCCEEEEEEEECCCCCCEEEEEEEECCCEEEEECCHHHHHHHHCCCCCCCEEEEEECCCC
ELKDKFIDHIDKMGIEITFERINNVYAMGEYFALMVNEKMYEAKTVILATGVEYGKALKG
HHHHHHHHHHHHCCCEEEEHHHCCCHHHHHEEEEEECCHHHHCEEEEEEECCHHHHHCCC
EEEFLGKGVGYCATCDAPLYKNKTVAIIGYNKEAEEEANFVSELASRLYYIPMYRSDYEL
CHHHHCCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHEEEEEEECCCCCH
SEKVEVINDKPIEIVGKQHVEKLILKDSEIEADGIFVLKDSISPAQLVPGLEMEDEHIKV
HHHHHHCCCCCCEEECHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHCCCCCCCCCCEEE
DRKMKTNISGCFAAGDCTGKPYQYIKSAGEGQIAALSAVSYLDKQSS
CCHHHCCCCEEEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
GKRYDIAIIGSGPAGLEAAINAKIRNKDIIIFGNKELSSKLVKAPKINNYLGFYDISGN
CCEEEEEEEECCCCCCEEEEEEEECCCEEEEECCHHHHHHHHCCCCCCCEEEEEECCCC
ELKDKFIDHIDKMGIEITFERINNVYAMGEYFALMVNEKMYEAKTVILATGVEYGKALKG
HHHHHHHHHHHHCCCEEEEHHHCCCHHHHHEEEEEECCHHHHCEEEEEEECCHHHHHCCC
EEEFLGKGVGYCATCDAPLYKNKTVAIIGYNKEAEEEANFVSELASRLYYIPMYRSDYEL
CHHHHCCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHEEEEEEECCCCCH
SEKVEVINDKPIEIVGKQHVEKLILKDSEIEADGIFVLKDSISPAQLVPGLEMEDEHIKV
HHHHHHCCCCCCEEECHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHCCCCCCCCCCEEE
DRKMKTNISGCFAAGDCTGKPYQYIKSAGEGQIAALSAVSYLDKQSS
CCHHHCCCCEEEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]