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The map label for this gene is cysS [H]

Identifier: 170751939

GI number: 170751939

Start: 5890172

End: 5891569

Strand: Direct

Name: cysS [H]

Synonym: Mrad2831_5571

Alternate gene names: 170751939

Gene position: 5890172-5891569 (Clockwise)

Preceding gene: 170751937

Following gene: 170751940

Centisome position: 96.91

GC content: 71.53

Gene sequence:

>1398_bases
ATGGCGCCGATGTTGCGGCTCTACAACACGCTGACCGGCGCCAAGGAGGCGTTCGCGCCGATCGACCCGCAGCATGTCCG
CGTCTACGCCTGCGGCCCGACGGTCTACGACGCCGCCCATATCGGCAACGCCCGACCGATCATCGTCTTCGACCTGCTGT
TCCGGCTGCTGCGCCACCTCTACGGGCCGGAGCACGTCACCTACGCCCGCAACGTCACGGACGTGGACGACAAGATCAAC
GCCCGGGCGGCCGAGCGCGGCGTCAGCATCCGCGAACTGACCGACGGCACGCTCGCGCAGTTCCACCGCGACGTGCGCGA
CCTCGGCGTGCTCATGCCGGAGGACGTGAACCTCACGGGCGCGCGGCCCCGCTTCGTCGAGCCCCGCGCCACCGACCACA
TCGTCGAGATGGTCACGATGATCGAGGCCCTGGTCCGGGCCGGCCACGCCTACGTGGCGGCGGATCACGTGCTGTTCGAC
GTCCCCTCGATGCCGGATTACGGCGGCCTGTCGAAGCGGCCCCTCGACGAGATGGAGGCGGGGGCCCGGGTCGAGGTCGC
CCCCTACAAGCGCTCGCCCCTCGACTTCGTCCTGTGGAAGCCCGCGAAGCCCGGCGAGCCGTCCTGGCCGTCGCCCGCCG
GGATCGCGGTCGCCGGGCGGCCGGGCTGGCACATCGAGTGCTCGGCCATGTCGGCCAAGCATCTCGGCCGGACCTTCGAC
ATCCACGCCGGCGGCATCGACCTGATCTTCCCGCACCACGAGAACGAGGTGGCGCAGTCGCGCTGCTGCTTCGGCACGCC
GGTGATGGCCAATGTCTGGCTGCACAACGGCTTCCTCCAGGTGGAGGGGGAGAAGATGTCGAAGTCGCTCGGCAACTTCA
TCACCATCCGCGACGTGCTGAACGACTGGCCGGGCGAGGTCGTGCGCCTCACCATGCTCAAGACCCAGTACCGGCAGCCG
ATCGACTGGACCCTGCGCGGCCTGGAGGAATCGGCCCGCGTGCTCGACCGCTGGTACAACGCCGCCGGCGACGCGCCCGC
CGCGTCCGACATCCCCGTCGGCGTTGTCGAGGCGCTCTGCGACGACCTCAACACGCCGGCGGCGATCAACGAACTTCACC
GGCTCGCGGGCGGCGCGGAGGCGCAGCCCGGTGCGCTGCGCGCCGGCGCGAATCTCCTCGGCTTCCTCGCGCGCACCCGC
AGCGACCGCGAGCAGGATCAGGTCGCGGCCTCGGGGGTCGACGTCGCGGCGGTCGAGGCGCTGATCGCCGCGCGCCGCGC
GGCCCGCGCCGCCAAAGACTGGGCCGCCTCCGACCGGGCGCGCGACGCCCTCGCGGCGATGGGCGTCGCCGTGAAGGACA
ACAAGGACGGCACCACGACCTGGACGGTGGCGCGCTGA

Upstream 100 bases:

>100_bases
TCGCCGCGCGGGGCCCTCAGGTCGTTGAAGGCAGGGCCGGATTTCCGGCCACGGCTCCGGTCCGGACGTCATCCCGGGCG
CCGGCAAAGGGATGGGTTTC

Downstream 100 bases:

>100_bases
TCGCGGAGCCGGCGGCCGATGACACGGATGTGACGGGGACCGCGTCCTCGCGCCCGCTTGCGCGGCGCGGCGCGGGCGGC
ATCTGTGGTCCGGGGACTCG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MAPMLRLYNTLTGAKEAFAPIDPQHVRVYACGPTVYDAAHIGNARPIIVFDLLFRLLRHLYGPEHVTYARNVTDVDDKIN
ARAAERGVSIRELTDGTLAQFHRDVRDLGVLMPEDVNLTGARPRFVEPRATDHIVEMVTMIEALVRAGHAYVAADHVLFD
VPSMPDYGGLSKRPLDEMEAGARVEVAPYKRSPLDFVLWKPAKPGEPSWPSPAGIAVAGRPGWHIECSAMSAKHLGRTFD
IHAGGIDLIFPHHENEVAQSRCCFGTPVMANVWLHNGFLQVEGEKMSKSLGNFITIRDVLNDWPGEVVRLTMLKTQYRQP
IDWTLRGLEESARVLDRWYNAAGDAPAASDIPVGVVEALCDDLNTPAAINELHRLAGGAEAQPGALRAGANLLGFLARTR
SDREQDQVAASGVDVAAVEALIAARRAARAAKDWAASDRARDALAAMGVAVKDNKDGTTTWTVAR

Sequences:

>Translated_465_residues
MAPMLRLYNTLTGAKEAFAPIDPQHVRVYACGPTVYDAAHIGNARPIIVFDLLFRLLRHLYGPEHVTYARNVTDVDDKIN
ARAAERGVSIRELTDGTLAQFHRDVRDLGVLMPEDVNLTGARPRFVEPRATDHIVEMVTMIEALVRAGHAYVAADHVLFD
VPSMPDYGGLSKRPLDEMEAGARVEVAPYKRSPLDFVLWKPAKPGEPSWPSPAGIAVAGRPGWHIECSAMSAKHLGRTFD
IHAGGIDLIFPHHENEVAQSRCCFGTPVMANVWLHNGFLQVEGEKMSKSLGNFITIRDVLNDWPGEVVRLTMLKTQYRQP
IDWTLRGLEESARVLDRWYNAAGDAPAASDIPVGVVEALCDDLNTPAAINELHRLAGGAEAQPGALRAGANLLGFLARTR
SDREQDQVAASGVDVAAVEALIAARRAARAAKDWAASDRARDALAAMGVAVKDNKDGTTTWTVAR
>Mature_464_residues
APMLRLYNTLTGAKEAFAPIDPQHVRVYACGPTVYDAAHIGNARPIIVFDLLFRLLRHLYGPEHVTYARNVTDVDDKINA
RAAERGVSIRELTDGTLAQFHRDVRDLGVLMPEDVNLTGARPRFVEPRATDHIVEMVTMIEALVRAGHAYVAADHVLFDV
PSMPDYGGLSKRPLDEMEAGARVEVAPYKRSPLDFVLWKPAKPGEPSWPSPAGIAVAGRPGWHIECSAMSAKHLGRTFDI
HAGGIDLIFPHHENEVAQSRCCFGTPVMANVWLHNGFLQVEGEKMSKSLGNFITIRDVLNDWPGEVVRLTMLKTQYRQPI
DWTLRGLEESARVLDRWYNAAGDAPAASDIPVGVVEALCDDLNTPAAINELHRLAGGAEAQPGALRAGANLLGFLARTRS
DREQDQVAASGVDVAAVEALIAARRAARAAKDWAASDRARDALAAMGVAVKDNKDGTTTWTVAR

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=523, Percent_Identity=33.0783938814532, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI62240992, Length=326, Percent_Identity=34.3558282208589, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI10835051, Length=326, Percent_Identity=34.0490797546012, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI21269877, Length=326, Percent_Identity=34.3558282208589, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI303304987, Length=326, Percent_Identity=34.3558282208589, Blast_Score=179, Evalue=3e-45,
Organism=Escherichia coli, GI1786737, Length=474, Percent_Identity=45.7805907172996, Blast_Score=373, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17509795, Length=329, Percent_Identity=33.1306990881459, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17509797, Length=329, Percent_Identity=33.1306990881459, Blast_Score=165, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6324082, Length=313, Percent_Identity=34.5047923322684, Blast_Score=169, Evalue=9e-43,
Organism=Drosophila melanogaster, GI19922218, Length=519, Percent_Identity=32.7552986512524, Blast_Score=225, Evalue=4e-59,
Organism=Drosophila melanogaster, GI19922364, Length=319, Percent_Identity=34.1692789968652, Blast_Score=173, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 50731; Mature: 50600

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPMLRLYNTLTGAKEAFAPIDPQHVRVYACGPTVYDAAHIGNARPIIVFDLLFRLLRHL
CCCHHHHHHHHHCCHHHCCCCCCCEEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHH
YGPEHVTYARNVTDVDDKINARAAERGVSIRELTDGTLAQFHRDVRDLGVLMPEDVNLTG
CCCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCC
ARPRFVEPRATDHIVEMVTMIEALVRAGHAYVAADHVLFDVPSMPDYGGLSKRPLDEMEA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCCCCCCCCCCCHHHHCC
GARVEVAPYKRSPLDFVLWKPAKPGEPSWPSPAGIAVAGRPGWHIECSAMSAKHLGRTFD
CCEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCEEEECCCCHHHCCCEEE
IHAGGIDLIFPHHENEVAQSRCCFGTPVMANVWLHNGFLQVEGEKMSKSLGNFITIRDVL
EECCCEEEEECCCCCHHHHHHCCCCCCHHHHHEEECCEEEECCHHHHHHHCCEEEHHHHH
NDWPGEVVRLTMLKTQYRQPIDWTLRGLEESARVLDRWYNAAGDAPAASDIPVGVVEALC
CCCCCHHEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
DDLNTPAAINELHRLAGGAEAQPGALRAGANLLGFLARTRSDREQDQVAASGVDVAAVEA
HCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHH
LIAARRAARAAKDWAASDRARDALAAMGVAVKDNKDGTTTWTVAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCEEEEEEC
>Mature Secondary Structure 
APMLRLYNTLTGAKEAFAPIDPQHVRVYACGPTVYDAAHIGNARPIIVFDLLFRLLRHL
CCHHHHHHHHHCCHHHCCCCCCCEEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHH
YGPEHVTYARNVTDVDDKINARAAERGVSIRELTDGTLAQFHRDVRDLGVLMPEDVNLTG
CCCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCC
ARPRFVEPRATDHIVEMVTMIEALVRAGHAYVAADHVLFDVPSMPDYGGLSKRPLDEMEA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCCCCCCCCCCCHHHHCC
GARVEVAPYKRSPLDFVLWKPAKPGEPSWPSPAGIAVAGRPGWHIECSAMSAKHLGRTFD
CCEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCEEEECCCCHHHCCCEEE
IHAGGIDLIFPHHENEVAQSRCCFGTPVMANVWLHNGFLQVEGEKMSKSLGNFITIRDVL
EECCCEEEEECCCCCHHHHHHCCCCCCHHHHHEEECCEEEECCHHHHHHHCCEEEHHHHH
NDWPGEVVRLTMLKTQYRQPIDWTLRGLEESARVLDRWYNAAGDAPAASDIPVGVVEALC
CCCCCHHEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
DDLNTPAAINELHRLAGGAEAQPGALRAGANLLGFLARTRSDREQDQVAASGVDVAAVEA
HCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHH
LIAARRAARAAKDWAASDRARDALAAMGVAVKDNKDGTTTWTVAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA