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The map label for this gene is nadA2 [H]

Identifier: 170751831

GI number: 170751831

Start: 5774285

End: 5775301

Strand: Direct

Name: nadA2 [H]

Synonym: Mrad2831_5463

Alternate gene names: 170751831

Gene position: 5774285-5775301 (Clockwise)

Preceding gene: 170751830

Following gene: 170751832

Centisome position: 95.01

GC content: 68.63

Gene sequence:

>1017_bases
ATGGCGGCGACCGTTGCACCCGTCTCCCGCACGACGATCCCGGGGCTGCCCCTTCCGGATCTCTACGCCCGCGTCAGCCG
GCACGTCCCCGCGATCGAGTGGCCGGCGCTCGCCCCCGACATCGAGGCGATCCTGCGCCTGAAGCGCGAGCGCAACGCCG
TCATCCTGGCGCACAACTACCAGGCGCCGGAGATCTTCCACACGGTGGCCGACATCGTCGGCGACAGCCTCGCGCTGGCC
CGCGAGGCCGTGAACGTCGACGCCGACGTGATCGTGCTGGCGGGCGTCCACTTCATGGCCGAGACCGCCAAGCTCCTGAA
CCCGAGCAAGACGGTGCTGATCCCCGACATGGGCGCCGGCTGCTCCCTGGCCGATTCGATCACCGCCGAGGACGTGCGCG
GTCTGCGCGCCAAGTACCCGGGCGTGCCGATCGTGACCTACGTGAACACCTCGGCGGCCGTTAAGGCCGAGTCCGACCTG
TGCTGCACCTCCGGCAACGCCGTCGCGGTGGTGAAGTCGCTGAACGCCCCCCGCGTTCTGATGATCCCCGACGAGTTCCT
CGCGCAGAACGTCCAGGCTGAGATCCCGGAGGTCGAGATCCTCACCTGGGCGGGCCACTGCGAGGTGCACGAGCGCTTCA
CCCCGGCCGACATCCGCGACGTCCGCGACAGCTATCCCGGCGTCACGGTGATCGCGCACCCGGAATGCCCGCCGGAGGTG
GTGGCCGAGTCGGACTTCTCCGGCTCCACGGCGATGATGATGGACTTCGTCGTCGAGAAGCGGCCGAAGCAGGTGGTGCT
CGTCACCGAGTGCTCGATGGCCGACAACATCGCGGCGCAGAACCCGGACATCGAATTCATCAAGCCCTGCAACATGTGCC
CGCACATGAAGCGGATGAGCCTGCGCAACATCCGGCGGTCGCTCGAGACGATGACCCACGAGGTCACGGTCGATCCGGCG
CTGGCCGACCGCGCCCGGGCAGCGGTGGAGCGCATGCTCCAGGTGCGCACGCGATGA

Upstream 100 bases:

>100_bases
GCAAAAGATTTATGCTCACAGCTAGCATATCTGGACAGGCGCGCGCGGCCCCCATAAGTTAGACGGCGCAATGCTCAAAC
TGAGCATAATGGAGGACGCC

Downstream 100 bases:

>100_bases
ACGCCGTCTCTCCCAACAACGCCGACCGCGTGGTCGTGGTCGGCGGCGGGGTCGCGGGCCTCAGCGTCGCGCTGCGCCTC
GCGCCCCGCCCGGTCACGCT

Product: quinolinate synthetase complex subunit A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MAATVAPVSRTTIPGLPLPDLYARVSRHVPAIEWPALAPDIEAILRLKRERNAVILAHNYQAPEIFHTVADIVGDSLALA
REAVNVDADVIVLAGVHFMAETAKLLNPSKTVLIPDMGAGCSLADSITAEDVRGLRAKYPGVPIVTYVNTSAAVKAESDL
CCTSGNAVAVVKSLNAPRVLMIPDEFLAQNVQAEIPEVEILTWAGHCEVHERFTPADIRDVRDSYPGVTVIAHPECPPEV
VAESDFSGSTAMMMDFVVEKRPKQVVLVTECSMADNIAAQNPDIEFIKPCNMCPHMKRMSLRNIRRSLETMTHEVTVDPA
LADRARAAVERMLQVRTR

Sequences:

>Translated_338_residues
MAATVAPVSRTTIPGLPLPDLYARVSRHVPAIEWPALAPDIEAILRLKRERNAVILAHNYQAPEIFHTVADIVGDSLALA
REAVNVDADVIVLAGVHFMAETAKLLNPSKTVLIPDMGAGCSLADSITAEDVRGLRAKYPGVPIVTYVNTSAAVKAESDL
CCTSGNAVAVVKSLNAPRVLMIPDEFLAQNVQAEIPEVEILTWAGHCEVHERFTPADIRDVRDSYPGVTVIAHPECPPEV
VAESDFSGSTAMMMDFVVEKRPKQVVLVTECSMADNIAAQNPDIEFIKPCNMCPHMKRMSLRNIRRSLETMTHEVTVDPA
LADRARAAVERMLQVRTR
>Mature_337_residues
AATVAPVSRTTIPGLPLPDLYARVSRHVPAIEWPALAPDIEAILRLKRERNAVILAHNYQAPEIFHTVADIVGDSLALAR
EAVNVDADVIVLAGVHFMAETAKLLNPSKTVLIPDMGAGCSLADSITAEDVRGLRAKYPGVPIVTYVNTSAAVKAESDLC
CTSGNAVAVVKSLNAPRVLMIPDEFLAQNVQAEIPEVEILTWAGHCEVHERFTPADIRDVRDSYPGVTVIAHPECPPEVV
AESDFSGSTAMMMDFVVEKRPKQVVLVTECSMADNIAAQNPDIEFIKPCNMCPHMKRMSLRNIRRSLETMTHEVTVDPAL
ADRARAAVERMLQVRTR

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=310, Percent_Identity=34.1935483870968, Blast_Score=167, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 36828; Mature: 36697

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATVAPVSRTTIPGLPLPDLYARVSRHVPAIEWPALAPDIEAILRLKRERNAVILAHNY
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECC
QAPEIFHTVADIVGDSLALAREAVNVDADVIVLAGVHFMAETAKLLNPSKTVLIPDMGAG
CCHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCCEEEEECCCCC
CSLADSITAEDVRGLRAKYPGVPIVTYVNTSAAVKAESDLCCTSGNAVAVVKSLNAPRVL
CCCHHCCCHHHHHHHHHCCCCCCEEEEECCCEEEECCCCCEECCCCEEEEEEECCCCEEE
MIPDEFLAQNVQAEIPEVEILTWAGHCEVHERFTPADIRDVRDSYPGVTVIAHPECPPEV
EECHHHHHCCHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCHHH
VAESDFSGSTAMMMDFVVEKRPKQVVLVTECSMADNIAAQNPDIEFIKPCNMCPHMKRMS
HCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHCCCCCCEEECCCCCCCHHHHHH
LRNIRRSLETMTHEVTVDPALADRARAAVERMLQVRTR
HHHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AATVAPVSRTTIPGLPLPDLYARVSRHVPAIEWPALAPDIEAILRLKRERNAVILAHNY
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECC
QAPEIFHTVADIVGDSLALAREAVNVDADVIVLAGVHFMAETAKLLNPSKTVLIPDMGAG
CCHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCCEEEEECCCCC
CSLADSITAEDVRGLRAKYPGVPIVTYVNTSAAVKAESDLCCTSGNAVAVVKSLNAPRVL
CCCHHCCCHHHHHHHHHCCCCCCEEEEECCCEEEECCCCCEECCCCEEEEEEECCCCEEE
MIPDEFLAQNVQAEIPEVEILTWAGHCEVHERFTPADIRDVRDSYPGVTVIAHPECPPEV
EECHHHHHCCHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCHHH
VAESDFSGSTAMMMDFVVEKRPKQVVLVTECSMADNIAAQNPDIEFIKPCNMCPHMKRMS
HCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHCCCCCCEEECCCCCCCHHHHHH
LRNIRRSLETMTHEVTVDPALADRARAAVERMLQVRTR
HHHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]