BacMap

Definition	Methylobacterium radiotolerans JCM 2831 chromosome, complete genome.
Accession	NC_010505
Length	6,077,833

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The map label for this gene is fabG3 [H]

Identifier: 170751771

GI number: 170751771

Start: 5706782

End: 5707558

Strand: Direct

Name: fabG3 [H]

Synonym: Mrad2831_5401

Alternate gene names: 170751771

Gene position: 5706782-5707558 (Clockwise)

Preceding gene: 170751769

Following gene: 170751777

Centisome position: 93.9

GC content: 73.62

Gene sequence:

>777_bases
ATGGCGGCGCAGCCGGATCAGCGCGCGCGGTATCCGAGCCTCGCCGGCAAGCGCGTCCTCGTGACCGGCGGCGCCTCGGG
CATCGGCGCGGGGCTGGTCGAGGCCTTCGTCGGGCAGGGGGCCCGCGTCCTGTTCTGCGATATCGCGGACGATGCGGCCC
GCGCCGTGGTGGCCCGTCTCGGGCCCGGCGCCGCGCACGCCCCGCTCTACCGGCGCTGCGACCTGACCGATGTCGACGCG
GTCCGCGCGCTGGTCGCCGAGGCCGACGCGGCCCTGGGCGGGCTCGACGTCCTGATCAACAATGCCGGCAACGACGACCG
CCACGCCCTCGCGGACGTGACGCCCGCCTACTGGGACGACCGGATGGCGGTGAACCTGCGCCACCTGTTCTTCGCCGCCC
AGGCGGCGGTCCCGGCCATGCAGCGCGCCGGCGGCGGCGTGATCCTCAACTTCGGATCGATCAGCTGGCATCTCGGGCTC
AGGGAGATGCCGCTCTACCAGACCGCCAAGGCGGCGATCGAGGGGATGACACGCGCCCTGGCCCGCGACCTCGGTCGCGA
CAACATCCGGGTGGCGACGGTCGTGCCCGGCAACGTTCAGACGCCCCGCCAGGAGCGATGGTACACGCCGGAGGGCGAGG
CGGAGATCGTCGCCGCGCAATGCCTCGACGGGCGGATCCAGCCGGCCGACGTCGCCGCGCTGGTCCTGTTCCTGGCCTCG
GACGACGCGCGCATGTGCACCGGCCACCCGTACTTCATCGACGCGGGCTGGCGCTGA

Upstream 100 bases:

>100_bases
GTTTCGCGAATCTCAGGCGGCCCCGCCACCGTTGCGGCGGCCGGCCACCGTGGTAAACTCAGACAAGTTCCGGTCTACCT
TAAAACCTCGAGGAGGTCCG

Downstream 100 bases:

>100_bases
ACCGAAGACGCGCAGGGGCCTGGCCGGGCTGAGCGCGCGGGACCGCGCTCCGGCCCGACGCGCTCGCGTGCCTCAGTCGC
AGCTCTCTTTCTTCACGGTC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MAAQPDQRARYPSLAGKRVLVTGGASGIGAGLVEAFVGQGARVLFCDIADDAARAVVARLGPGAAHAPLYRRCDLTDVDA
VRALVAEADAALGGLDVLINNAGNDDRHALADVTPAYWDDRMAVNLRHLFFAAQAAVPAMQRAGGGVILNFGSISWHLGL
REMPLYQTAKAAIEGMTRALARDLGRDNIRVATVVPGNVQTPRQERWYTPEGEAEIVAAQCLDGRIQPADVAALVLFLAS
DDARMCTGHPYFIDAGWR

Sequences:

>Translated_258_residues
MAAQPDQRARYPSLAGKRVLVTGGASGIGAGLVEAFVGQGARVLFCDIADDAARAVVARLGPGAAHAPLYRRCDLTDVDA
VRALVAEADAALGGLDVLINNAGNDDRHALADVTPAYWDDRMAVNLRHLFFAAQAAVPAMQRAGGGVILNFGSISWHLGL
REMPLYQTAKAAIEGMTRALARDLGRDNIRVATVVPGNVQTPRQERWYTPEGEAEIVAAQCLDGRIQPADVAALVLFLAS
DDARMCTGHPYFIDAGWR
>Mature_257_residues
AAQPDQRARYPSLAGKRVLVTGGASGIGAGLVEAFVGQGARVLFCDIADDAARAVVARLGPGAAHAPLYRRCDLTDVDAV
RALVAEADAALGGLDVLINNAGNDDRHALADVTPAYWDDRMAVNLRHLFFAAQAAVPAMQRAGGGVILNFGSISWHLGLR
EMPLYQTAKAAIEGMTRALARDLGRDNIRVATVVPGNVQTPRQERWYTPEGEAEIVAAQCLDGRIQPADVAALVLFLASD
DARMCTGHPYFIDAGWR

Specific function: Catalyzes A Reversible Reduction Of 5-Ketoglutanate To Form D-Gluconate. Dependent On Nadp, Almost Inactive With NAD. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI59889578, Length=230, Percent_Identity=34.7826086956522, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI15277342, Length=266, Percent_Identity=33.0827067669173, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI66933014, Length=250, Percent_Identity=32, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=29.6, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI7705925, Length=247, Percent_Identity=31.5789473684211, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI109715829, Length=243, Percent_Identity=29.2181069958848, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI31542939, Length=242, Percent_Identity=27.6859504132231, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=29.2181069958848, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI4758504, Length=242, Percent_Identity=31.404958677686, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=24.21875, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=26.7716535433071, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=28.0334728033473, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=30.4123711340206, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI224922801, Length=171, Percent_Identity=29.2397660818713, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI20149619, Length=224, Percent_Identity=26.7857142857143, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI4504505, Length=247, Percent_Identity=28.3400809716599, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI10190704, Length=245, Percent_Identity=28.9795918367347, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI83715985, Length=233, Percent_Identity=29.6137339055794, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=29.5081967213115, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=30.241935483871, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=30.1204819277108, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=33.3333333333333, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=30.4878048780488, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=29.7619047619048, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1789378, Length=241, Percent_Identity=31.1203319502075, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=27.2, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI2367365, Length=254, Percent_Identity=30.3149606299213, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788459, Length=170, Percent_Identity=32.3529411764706, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787526, Length=254, Percent_Identity=25.9842519685039, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786812, Length=252, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789057, Length=250, Percent_Identity=28, Blast_Score=68, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=31.7073170731707, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=31.3008130081301, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=27.6679841897233, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17544670, Length=272, Percent_Identity=27.9411764705882, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=29.0322580645161, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=29.9180327868852, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=27.710843373494, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=202, Percent_Identity=32.6732673267327, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=27.8625954198473, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=172, Percent_Identity=28.4883720930233, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=253, Percent_Identity=28.8537549407115, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=242, Percent_Identity=29.7520661157025, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=200, Percent_Identity=26, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=244, Percent_Identity=30.7377049180328, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=244, Percent_Identity=27.8688524590164, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=251, Percent_Identity=29.0836653386454, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=241, Percent_Identity=27.8008298755187, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=191, Percent_Identity=24.6073298429319, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=188, Percent_Identity=25, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=243, Percent_Identity=28.8065843621399, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71997099, Length=211, Percent_Identity=28.9099526066351, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=26.1538461538462, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=242, Percent_Identity=26.0330578512397, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=25.1908396946565, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=198, Percent_Identity=25.7575757575758, Blast_Score=62, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=29.6153846153846, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=29.718875502008, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI21355319, Length=241, Percent_Identity=26.9709543568465, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=27.7777777777778, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=29.4354838709677, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=27.9527559055118, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=28.1746031746032, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24644337, Length=258, Percent_Identity=31.7829457364341, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI281364892, Length=195, Percent_Identity=29.2307692307692, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17737361, Length=195, Percent_Identity=31.7948717948718, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=27.8350515463918, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24665243, Length=258, Percent_Identity=28.6821705426357, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221331218, Length=258, Percent_Identity=28.6821705426357, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281364494, Length=245, Percent_Identity=27.7551020408163, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24665247, Length=259, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI221331216, Length=259, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI116007236, Length=192, Percent_Identity=25.5208333333333, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.53 [H]

Molecular weight: Translated: 27413; Mature: 27282

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAQPDQRARYPSLAGKRVLVTGGASGIGAGLVEAFVGQGARVLFCDIADDAARAVVARL
CCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHC
GPGAAHAPLYRRCDLTDVDAVRALVAEADAALGGLDVLINNAGNDDRHALADVTPAYWDD
CCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHCCCCCCCC
RMAVNLRHLFFAAQAAVPAMQRAGGGVILNFGSISWHLGLREMPLYQTAKAAIEGMTRAL
CCEEHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEECCCCCCCHHHHHHHHHHHHHHHH
ARDLGRDNIRVATVVPGNVQTPRQERWYTPEGEAEIVAAQCLDGRIQPADVAALVLFLAS
HHHCCCCCEEEEEEECCCCCCCHHHCCCCCCCCCEEEEEEHHCCCCCHHHHHHHHHHHCC
DDARMCTGHPYFIDAGWR
CCCCEECCCCEEEECCCC
>Mature Secondary Structure 
AAQPDQRARYPSLAGKRVLVTGGASGIGAGLVEAFVGQGARVLFCDIADDAARAVVARL
CCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHC
GPGAAHAPLYRRCDLTDVDAVRALVAEADAALGGLDVLINNAGNDDRHALADVTPAYWDD
CCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHCCCCCCCC
RMAVNLRHLFFAAQAAVPAMQRAGGGVILNFGSISWHLGLREMPLYQTAKAAIEGMTRAL
CCEEHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEECCCCCCCHHHHHHHHHHHHHHHH
ARDLGRDNIRVATVVPGNVQTPRQERWYTPEGEAEIVAAQCLDGRIQPADVAALVLFLAS
HHHCCCCCEEEEEEECCCCCCCHHHCCCCCCCCCEEEEEEHHCCCCCHHHHHHHHHHHCC
DDARMCTGHPYFIDAGWR
CCCCEECCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]