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The map label for this gene is yeiE [H]

Identifier: 170751636

GI number: 170751636

Start: 5582061

End: 5582951

Strand: Direct

Name: yeiE [H]

Synonym: Mrad2831_5262

Alternate gene names: 170751636

Gene position: 5582061-5582951 (Clockwise)

Preceding gene: 170751635

Following gene: 170751637

Centisome position: 91.84

GC content: 72.28

Gene sequence:

>891_bases
ATGACCCTTGACCAGCTTCGCATCTTCGTGGCGGTGGCCGAGCGGCAGCACGTGACGCGGGCCGCCGAGGCGCTGAACCT
CGTCCAGTCGGCGGTCAGCACGGCGATCGCCAACATCGAGGGGCGGCACGCGACGAAGCTGTTTCACCGGGTTGGCCGCG
GGATCGAACTGACCGAAGCGGGGCGCGTGTTCCTCGTCGAGGCCCGCGCCGTGCTCGCCCGGGCCGAGGCCGCCGAACTT
GTGCTCGCCGACCTCAGCGGCATGCGACGCGGGACGCTGGCGCTCTACGCCAGCCAGACCATCGCGAGCGATTGGTTGCC
GCGCCACCTCGTCGCCTTCCGCCGCACCTACCCTGAGATCGCCCTGCGCTTGGCCGTGGGCAACACCACCGACGCCGCCG
ACGCGGTGCGCGCCGGGCAGGCCGAACTCGGCTTCGTCGAGGGGGCGTTGGACGACCCGACGCTTGCGAGCACCACCATC
GCGCGGGACCAACTCGTTCTCGTGGTCGCCCCAAACCATCACTTCGCCGGGGCGACCGCCCTCGCACCCGAAGACCTCGC
CGGGGCCGATTGGGTGCTGCGCGAGGCTGGATCGGGAACCCGCTCGGCCTTCGAGGCGGCGCTCACGGAGGCTGGCCTCG
CCCCGGCCCAACTCCGGGTCACGCTCGAACTGCCCTCGAACGAGGCGGTGCGCGCCGCCGTCGAGGCCGGGGGCGGGGCC
ACCGTCCTGTCCGAGACCGTGGTCGCCGCCGCGATTCGGGCCGGGACCCTGGTGCGGGCGGCGTTCGAGTTGCCAAGCCG
ACCCTTCCGGGTGCTGCGCCACAAGGAGCGCTACCGCAGTCGGGCCGCCGACGCGCTGCTCGAACTCATCGCAACGTCGG
ATCCCGGATGA

Upstream 100 bases:

>100_bases
CCTACGTCGTCACCGGCCGCACCGACGAGGCCCGGCTGCTCACCGTCGCGCAGGCGGTCGATGCGCAGGTCCGCGGCCTC
GCGCCGGATCGTCGGCAGCC

Downstream 100 bases:

>100_bases
GCGAGCCTGCGAAACCCGTGCCCCCCCCGACGACCCGCGGGTGAGGCTCGCCAAGGACCGGACTCGGCGTCGGCCTGGCC
GCTTAGCGCTTCCTGCGGGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MTLDQLRIFVAVAERQHVTRAAEALNLVQSAVSTAIANIEGRHATKLFHRVGRGIELTEAGRVFLVEARAVLARAEAAEL
VLADLSGMRRGTLALYASQTIASDWLPRHLVAFRRTYPEIALRLAVGNTTDAADAVRAGQAELGFVEGALDDPTLASTTI
ARDQLVLVVAPNHHFAGATALAPEDLAGADWVLREAGSGTRSAFEAALTEAGLAPAQLRVTLELPSNEAVRAAVEAGGGA
TVLSETVVAAAIRAGTLVRAAFELPSRPFRVLRHKERYRSRAADALLELIATSDPG

Sequences:

>Translated_296_residues
MTLDQLRIFVAVAERQHVTRAAEALNLVQSAVSTAIANIEGRHATKLFHRVGRGIELTEAGRVFLVEARAVLARAEAAEL
VLADLSGMRRGTLALYASQTIASDWLPRHLVAFRRTYPEIALRLAVGNTTDAADAVRAGQAELGFVEGALDDPTLASTTI
ARDQLVLVVAPNHHFAGATALAPEDLAGADWVLREAGSGTRSAFEAALTEAGLAPAQLRVTLELPSNEAVRAAVEAGGGA
TVLSETVVAAAIRAGTLVRAAFELPSRPFRVLRHKERYRSRAADALLELIATSDPG
>Mature_295_residues
TLDQLRIFVAVAERQHVTRAAEALNLVQSAVSTAIANIEGRHATKLFHRVGRGIELTEAGRVFLVEARAVLARAEAAELV
LADLSGMRRGTLALYASQTIASDWLPRHLVAFRRTYPEIALRLAVGNTTDAADAVRAGQAELGFVEGALDDPTLASTTIA
RDQLVLVVAPNHHFAGATALAPEDLAGADWVLREAGSGTRSAFEAALTEAGLAPAQLRVTLELPSNEAVRAAVEAGGGAT
VLSETVVAAAIRAGTLVRAAFELPSRPFRVLRHKERYRSRAADALLELIATSDPG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788481, Length=297, Percent_Identity=34.6801346801347, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1787530, Length=251, Percent_Identity=28.6852589641434, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI145693105, Length=241, Percent_Identity=25.3112033195021, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI157672245, Length=287, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788748, Length=294, Percent_Identity=26.8707482993197, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787806, Length=248, Percent_Identity=26.2096774193548, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788887, Length=197, Percent_Identity=30.9644670050761, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87082132, Length=263, Percent_Identity=26.2357414448669, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787601, Length=196, Percent_Identity=23.9795918367347, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790399, Length=244, Percent_Identity=23.7704918032787, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790262, Length=196, Percent_Identity=26.530612244898, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787879, Length=250, Percent_Identity=27.2, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788296, Length=220, Percent_Identity=29.5454545454545, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=23.5494880546075, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788297, Length=125, Percent_Identity=32.8, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI87081904, Length=175, Percent_Identity=31.4285714285714, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790208, Length=171, Percent_Identity=28.6549707602339, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789173, Length=256, Percent_Identity=26.5625, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789204, Length=268, Percent_Identity=26.1194029850746, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789639, Length=190, Percent_Identity=26.8421052631579, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787128, Length=301, Percent_Identity=27.5747508305648, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI2367136, Length=259, Percent_Identity=26.2548262548263, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788706, Length=139, Percent_Identity=35.2517985611511, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31317; Mature: 31186

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDQLRIFVAVAERQHVTRAAEALNLVQSAVSTAIANIEGRHATKLFHRVGRGIELTEA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECC
GRVFLVEARAVLARAEAAELVLADLSGMRRGTLALYASQTIASDWLPRHLVAFRRTYPEI
CCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCHHH
ALRLAVGNTTDAADAVRAGQAELGFVEGALDDPTLASTTIARDQLVLVVAPNHHFAGATA
EEEEEECCCCCHHHHHHCCCCHHCEECCCCCCCCHHHHEECCCEEEEEEECCCCCCCCCC
LAPEDLAGADWVLREAGSGTRSAFEAALTEAGLAPAQLRVTLELPSNEAVRAAVEAGGGA
CCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHCCCCH
TVLSETVVAAAIRAGTLVRAAFELPSRPFRVLRHKERYRSRAADALLELIATSDPG
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TLDQLRIFVAVAERQHVTRAAEALNLVQSAVSTAIANIEGRHATKLFHRVGRGIELTEA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEECC
GRVFLVEARAVLARAEAAELVLADLSGMRRGTLALYASQTIASDWLPRHLVAFRRTYPEI
CCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCHHH
ALRLAVGNTTDAADAVRAGQAELGFVEGALDDPTLASTTIARDQLVLVVAPNHHFAGATA
EEEEEECCCCCHHHHHHCCCCHHCEECCCCCCCCHHHHEECCCEEEEEEECCCCCCCCCC
LAPEDLAGADWVLREAGSGTRSAFEAALTEAGLAPAQLRVTLELPSNEAVRAAVEAGGGA
CCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHCCCCH
TVLSETVVAAAIRAGTLVRAAFELPSRPFRVLRHKERYRSRAADALLELIATSDPG
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]