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The map label for this gene is 170751614

Identifier: 170751614

GI number: 170751614

Start: 5557838

End: 5559553

Strand: Direct

Name: 170751614

Synonym: Mrad2831_5235

Alternate gene names: NA

Gene position: 5557838-5559553 (Clockwise)

Preceding gene: 170751613

Following gene: 170751616

Centisome position: 91.44

GC content: 69.52

Gene sequence:

>1716_bases
ATGCTGACCCGACGCATCCTCGCCCTGGTGGCGCTCGCCCTGGCGCCCGCGCTCGCGATCCAGGGCTACAACGAGTACGC
CCTGCGTACGTCACGCGATGCGGCGGTGCGGGCCGATGCGCTGGGCACCGCCCGGACCGTGGCCGCCGACCTGGGGCAGC
TCGCGCAGAGCCTGCGTCAGGTGCTTGACCTCGTCGGCAACGAGGAGGCCGTGCGGCGCAAGGATGCCGGCGCCTGCACC
GCCTACCTCGGGGCGATCATCGACCGGCTGCCGCAACTCAGCCTGCTCTCCGTCGCCGAACCCGATGGACGCGTCGTGTG
CGACTCCCGCGGTTCCACACCCGGGCTCTACTCGAACGCCGAGCGTGCCTACCACAAGCGCGTCTTGGCCAGCGATGACT
TCGCGGTGGGCGACTTCGTGATCGGCGTGCGCACGCGTCAGCCGGCGGTGCACTTCGCACAGCCCGTGCGCGGGTATGAC
GACCGCCTCACCGGCGTGGTCGTGGCCAGCGTCGACCTCGCCCGACTGTCGGAGCGCCTGCAGGCGGATTTGCGCTTCGC
CAGCACCACCCTGACGGTCACTGACCCGGAGGGAACGGTCTTGGTGCGCCGACCGGATCACGCGGCATGGGTCGGGCGCA
AGCTTTCAGGCGAGCGGCTGGCGCGGCTGATGCGAGCCGACGAGACCACCCGTTCCGTCGAAGGTCTCGACGGACGTGCG
CGCATCGTCGGTATCGCCAAGCCCGATGGCGCTCTCGCGGGATTCAACGTCATCGTCGGCCGGGACCGCGAGACGGCGTT
CGCCGACATCGATGCCGCCACCTATCGCGGCATAGCCGTAATCCTGCTCGGTGCCCTCCTCGCGGTGCTGGCGACGCTTC
TCGCGGGAAGGCGCTTCATCGAGCGGCCGGTGCGGCGCCTCCTGCGGGGCGTTGCCGCTTGGCAGGGGGGCGACCTCGAT
GCAAGGACCGGGATGAGCGGCCCCTCGGAGTTCGACCGCCTGGGCGCGGCGTTCGACGCCATGGCCACGACGCTTCAGGG
CCGGGAGGATGACCTGCACGGCGAGATCGCCCGGGGACGGAGGATGCAGGAGCAGCAGACGACGATGCTGCACGAGTTGA
ACCACCGAGTGAAGAACACGCTGGCCACGGTCCAATCGCTGGCACGCCAGGCACGCGGCGGCGAGGAGCAGGCGGCGCAA
CTGGAGGCCCGCATCCTCGCCCTGTCGAAGACGCACGACCTGCTGACCCGCGAGGATTGGACGGGCGCCTCGTTGCGGGA
CGTGATGGAGAACGAGCTGTCCCCTTACCGCACCGGCGACGACCACATCACCCTGGACGGACCGGACGTGCCCTTGCCGC
CACGCTACGCGCTCGCCATCGGCATGACGGTGCATGAACTGGCGACCAACGCGGCCAAGTACGGGGCCCTGTCGGATGTC
GGCGGGCAGGTCTGCGTCGCATGGCGTCTCGTGCATTGCGAGGGAGGTGGTCGACGCCTGCATCTCGACTGGCAGGAGAG
CGGCGGACCCCGGGTCGAGCCACCCTCCAGGAGTGGTTTTGGCACGAGGCTGATCGCTGGCGGAATGCAACGAGAACTCG
GCGGCGAGGTAAGTCTGACGTTCGATCCGACCGGGCTGCGCTGCCTTCTCGACGTACCGCTCCAGGGTAGCCACACGAGC
ATGCTGAGCCCGCTGGCGGATGGGTTGGCCCACTGA

Upstream 100 bases:

>100_bases
CAGAAGCCCTATTCGGCCGATGACCTGTCGAGGGTATTTCGGCGCGTGACGAGCCGGCGCCCGCATCCGACGCCTTTGCC
GGACTGAGCGCTCAGCCCCT

Downstream 100 bases:

>100_bases
GACAGTCGCAGCCCCGTTCTCCGCTCGGAATCCCGAGGACCCATGCGGCCGGGTCGGAAGAAGTCTGGATCGGACCGTGC
CGTCGGCAGGATGATGGTCG

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 571; Mature: 571

Protein sequence:

>571_residues
MLTRRILALVALALAPALAIQGYNEYALRTSRDAAVRADALGTARTVAADLGQLAQSLRQVLDLVGNEEAVRRKDAGACT
AYLGAIIDRLPQLSLLSVAEPDGRVVCDSRGSTPGLYSNAERAYHKRVLASDDFAVGDFVIGVRTRQPAVHFAQPVRGYD
DRLTGVVVASVDLARLSERLQADLRFASTTLTVTDPEGTVLVRRPDHAAWVGRKLSGERLARLMRADETTRSVEGLDGRA
RIVGIAKPDGALAGFNVIVGRDRETAFADIDAATYRGIAVILLGALLAVLATLLAGRRFIERPVRRLLRGVAAWQGGDLD
ARTGMSGPSEFDRLGAAFDAMATTLQGREDDLHGEIARGRRMQEQQTTMLHELNHRVKNTLATVQSLARQARGGEEQAAQ
LEARILALSKTHDLLTREDWTGASLRDVMENELSPYRTGDDHITLDGPDVPLPPRYALAIGMTVHELATNAAKYGALSDV
GGQVCVAWRLVHCEGGGRRLHLDWQESGGPRVEPPSRSGFGTRLIAGGMQRELGGEVSLTFDPTGLRCLLDVPLQGSHTS
MLSPLADGLAH

Sequences:

>Translated_571_residues
MLTRRILALVALALAPALAIQGYNEYALRTSRDAAVRADALGTARTVAADLGQLAQSLRQVLDLVGNEEAVRRKDAGACT
AYLGAIIDRLPQLSLLSVAEPDGRVVCDSRGSTPGLYSNAERAYHKRVLASDDFAVGDFVIGVRTRQPAVHFAQPVRGYD
DRLTGVVVASVDLARLSERLQADLRFASTTLTVTDPEGTVLVRRPDHAAWVGRKLSGERLARLMRADETTRSVEGLDGRA
RIVGIAKPDGALAGFNVIVGRDRETAFADIDAATYRGIAVILLGALLAVLATLLAGRRFIERPVRRLLRGVAAWQGGDLD
ARTGMSGPSEFDRLGAAFDAMATTLQGREDDLHGEIARGRRMQEQQTTMLHELNHRVKNTLATVQSLARQARGGEEQAAQ
LEARILALSKTHDLLTREDWTGASLRDVMENELSPYRTGDDHITLDGPDVPLPPRYALAIGMTVHELATNAAKYGALSDV
GGQVCVAWRLVHCEGGGRRLHLDWQESGGPRVEPPSRSGFGTRLIAGGMQRELGGEVSLTFDPTGLRCLLDVPLQGSHTS
MLSPLADGLAH
>Mature_571_residues
MLTRRILALVALALAPALAIQGYNEYALRTSRDAAVRADALGTARTVAADLGQLAQSLRQVLDLVGNEEAVRRKDAGACT
AYLGAIIDRLPQLSLLSVAEPDGRVVCDSRGSTPGLYSNAERAYHKRVLASDDFAVGDFVIGVRTRQPAVHFAQPVRGYD
DRLTGVVVASVDLARLSERLQADLRFASTTLTVTDPEGTVLVRRPDHAAWVGRKLSGERLARLMRADETTRSVEGLDGRA
RIVGIAKPDGALAGFNVIVGRDRETAFADIDAATYRGIAVILLGALLAVLATLLAGRRFIERPVRRLLRGVAAWQGGDLD
ARTGMSGPSEFDRLGAAFDAMATTLQGREDDLHGEIARGRRMQEQQTTMLHELNHRVKNTLATVQSLARQARGGEEQAAQ
LEARILALSKTHDLLTREDWTGASLRDVMENELSPYRTGDDHITLDGPDVPLPPRYALAIGMTVHELATNAAKYGALSDV
GGQVCVAWRLVHCEGGGRRLHLDWQESGGPRVEPPSRSGFGTRLIAGGMQRELGGEVSLTFDPTGLRCLLDVPLQGSHTS
MLSPLADGLAH

Specific function: Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG3920

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR013655
- InterPro:   IPR011102 [H]

Pfam domain/function: PF07536 HWE_HK; PF00989 PAS; PF08447 PAS_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61502; Mature: 61502

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS50885 HAMP ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTRRILALVALALAPALAIQGYNEYALRTSRDAAVRADALGTARTVAADLGQLAQSLRQ
CHHHHHHHHHHHHHHHHHHHCCCCHHHEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
VLDLVGNEEAVRRKDAGACTAYLGAIIDRLPQLSLLSVAEPDGRVVCDSRGSTPGLYSNA
HHHHHCCHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEECCCCCCCCCCCCH
ERAYHKRVLASDDFAVGDFVIGVRTRQPAVHFAQPVRGYDDRLTGVVVASVDLARLSERL
HHHHHHHHHCCCCCEECEEEEEEECCCCHHHHHHHCCCCCCHHCEEEEEHHHHHHHHHHH
QADLRFASTTLTVTDPEGTVLVRRPDHAAWVGRKLSGERLARLMRADETTRSVEGLDGRA
HHHHHEEEEEEEEECCCCEEEEECCCCHHHHCCCCCHHHHHHHHHHCHHHHHHCCCCCCE
RIVGIAKPDGALAGFNVIVGRDRETAFADIDAATYRGIAVILLGALLAVLATLLAGRRFI
EEEEEECCCCCEECCEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
ERPVRRLLRGVAAWQGGDLDARTGMSGPSEFDRLGAAFDAMATTLQGREDDLHGEIARGR
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
RMQEQQTTMLHELNHRVKNTLATVQSLARQARGGEEQAAQLEARILALSKTHDLLTREDW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
TGASLRDVMENELSPYRTGDDHITLDGPDVPLPPRYALAIGMTVHELATNAAKYGALSDV
CCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCHHHEECCHHHHHHHHHHHCCCHHHC
GGQVCVAWRLVHCEGGGRRLHLDWQESGGPRVEPPSRSGFGTRLIAGGMQRELGGEVSLT
CCCEEEEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHCCHHHHCCCEEEEE
FDPTGLRCLLDVPLQGSHTSMLSPLADGLAH
ECCCCCEEEEECCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTRRILALVALALAPALAIQGYNEYALRTSRDAAVRADALGTARTVAADLGQLAQSLRQ
CHHHHHHHHHHHHHHHHHHHCCCCHHHEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
VLDLVGNEEAVRRKDAGACTAYLGAIIDRLPQLSLLSVAEPDGRVVCDSRGSTPGLYSNA
HHHHHCCHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEECCCCCCCCCCCCH
ERAYHKRVLASDDFAVGDFVIGVRTRQPAVHFAQPVRGYDDRLTGVVVASVDLARLSERL
HHHHHHHHHCCCCCEECEEEEEEECCCCHHHHHHHCCCCCCHHCEEEEEHHHHHHHHHHH
QADLRFASTTLTVTDPEGTVLVRRPDHAAWVGRKLSGERLARLMRADETTRSVEGLDGRA
HHHHHEEEEEEEEECCCCEEEEECCCCHHHHCCCCCHHHHHHHHHHCHHHHHHCCCCCCE
RIVGIAKPDGALAGFNVIVGRDRETAFADIDAATYRGIAVILLGALLAVLATLLAGRRFI
EEEEEECCCCCEECCEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
ERPVRRLLRGVAAWQGGDLDARTGMSGPSEFDRLGAAFDAMATTLQGREDDLHGEIARGR
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
RMQEQQTTMLHELNHRVKNTLATVQSLARQARGGEEQAAQLEARILALSKTHDLLTREDW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
TGASLRDVMENELSPYRTGDDHITLDGPDVPLPPRYALAIGMTVHELATNAAKYGALSDV
CCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCHHHEECCHHHHHHHHHHHCCCHHHC
GGQVCVAWRLVHCEGGGRRLHLDWQESGGPRVEPPSRSGFGTRLIAGGMQRELGGEVSLT
CCCEEEEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHCCHHHHCCCEEEEE
FDPTGLRCLLDVPLQGSHTSMLSPLADGLAH
ECCCCCEEEEECCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA