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The map label for this gene is rsbS [H]

Identifier: 170751609

GI number: 170751609

Start: 5550757

End: 5551158

Strand: Direct

Name: rsbS [H]

Synonym: Mrad2831_5230

Alternate gene names: 170751609

Gene position: 5550757-5551158 (Clockwise)

Preceding gene: 170751608

Following gene: 170751610

Centisome position: 91.33

GC content: 67.91

Gene sequence:

>402_bases
ATGGAGCGCATCCCGATCCTCAAGCTGGGTGGCGTGCTGATCGTCACCATCCAGGTCGACATGCACGACCGCCTCGCGCT
CGCCCTGGAGGAGGACCTCACGGCGATGATCGCGCGCACCGGCGCGCGCGGCGTCCTGCTCGAAATCTCGGCGCTGGAAA
TCGTCGATTCCTTCATCGGCCGGATGCTGGTGAGTATCGCCGCGGTCTCGCGCGTCCTCGACGCCGAGACCGTCGTGGCG
GGCATGCGGCCCGCGGTGGCCATCACGTTGGTCGAGCTCGGCCTGGAGCTCACCGGCATCAGGACCGCGCTCAACGTCGA
GCGGGGCATGGCGCTGATCCAGGCCCGGATTTCCGAGGAGGACGACGGACACGGGAGCGACCGTGACCGTCACGAAGACT
GA

Upstream 100 bases:

>100_bases
TCGAAGGCCACCCTGGCCGACGCCTTCGCGGTCGCCCTGAGGCGGACCGGCCGTAAGGTGGTGCGGCAGCAGGCGGCGGT
CGAGGAGCGCCGCTGACGCC

Downstream 100 bases:

>100_bases
GACCTTGCCCGTCAGATCCGGCGACGACGTCGTCCGCGTGCGGCAGCGCGTGCGTGCGCTCGCCGTGGAAATCGGCCTCG
GCCTCGTCGACCAGACCAAG

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbS [H]

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MERIPILKLGGVLIVTIQVDMHDRLALALEEDLTAMIARTGARGVLLEISALEIVDSFIGRMLVSIAAVSRVLDAETVVA
GMRPAVAITLVELGLELTGIRTALNVERGMALIQARISEEDDGHGSDRDRHED

Sequences:

>Translated_133_residues
MERIPILKLGGVLIVTIQVDMHDRLALALEEDLTAMIARTGARGVLLEISALEIVDSFIGRMLVSIAAVSRVLDAETVVA
GMRPAVAITLVELGLELTGIRTALNVERGMALIQARISEEDDGHGSDRDRHED
>Mature_133_residues
MERIPILKLGGVLIVTIQVDMHDRLALALEEDLTAMIARTGARGVLLEISALEIVDSFIGRMLVSIAAVSRVLDAETVVA
GMRPAVAITLVELGLELTGIRTALNVERGMALIQARISEEDDGHGSDRDRHED

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 14352; Mature: 14352

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERIPILKLGGVLIVTIQVDMHDRLALALEEDLTAMIARTGARGVLLEISALEIVDSFIG
CCCCCEEEECCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHH
RMLVSIAAVSRVLDAETVVAGMRPAVAITLVELGLELTGIRTALNVERGMALIQARISEE
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
DDGHGSDRDRHED
CCCCCCCCCCCCC
>Mature Secondary Structure
MERIPILKLGGVLIVTIQVDMHDRLALALEEDLTAMIARTGARGVLLEISALEIVDSFIG
CCCCCEEEECCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHH
RMLVSIAAVSRVLDAETVVAGMRPAVAITLVELGLELTGIRTALNVERGMALIQARISEE
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
DDGHGSDRDRHED
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 8824586; 8682789 [H]