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The map label for this gene is 170751541

Identifier: 170751541

GI number: 170751541

Start: 5488677

End: 5490866

Strand: Direct

Name: 170751541

Synonym: Mrad2831_5161

Alternate gene names: NA

Gene position: 5488677-5490866 (Clockwise)

Preceding gene: 170751532

Following gene: 170751542

Centisome position: 90.31

GC content: 76.07

Gene sequence:

>2190_bases
ATGCCGTTCTTCGCTCCACGATCCGCGCTCGAGCCCCCCCGCAACGCCGCGCTGTCACCCCTCTTCCTCGCGCTGCTGGC
GCTCCTCGTCATGCTCGCCTCGGCCCACGCGGCGCCGGGGCCGGCACGGGGCGGCCTCACGCTGCGCGGGCCGTCCGGCA
CCGCGCCGGTCGAGGCCGTCCAGCTCGCGACCGACATCAGCGTCGACGTCAGCGGCCCGACCGCCCGGGCCACCGTCACC
CAGGCCTTCCGCAACGTCACGGCGGAGTGGGTCGAGGGCACCTACCTGTACCCCCTGCCGGAGGACGCGGCCGTCGACAG
GATGAAGCTCGTCGTCGGCTCCCGCGTGATCATCGCCGACATCCGCGAGCGGGCGGCGGCCAAGCGCGCCTACGAGGCCG
CGAAGGCGGCCGGGCAAGCGGCGGCGCTCACCGCGCAGGAGCGGCCCAACGTGTTCACCAACGCGGTCGCCAATATCGGC
CCCGGCGAGACGGTGCTGGTCCAGATCACCTATCAGCAGACGATCCCCGTCTCCGGCGAGACGCGGACGCTGCGCCTGCC
CCTGGTCGTCGCGCCCCGCTACAATCCCGCCCCCACCTCGGTGGACGCGGTCTCCCTCGACGGCCCGGCCGCGGCGGCCC
GCGACCCGGTTCCGGATCGCGCCCGGATCAGCCCGCCGGTGCTCGACCCGGCCCTGTCCGCGCCGACCAACCCGGTCGCC
GTCACCGTGCGGCTCCGGGCGGGCTTCGCCGTCGGCGCCGTTCAGAGCGCGACCCACGCGATCCGCGTGATCGAGACCGG
CCCGGAGGCGCGGACCGTCACGCTCGCCGAGGGCGTCGTGCCGGCCGACCGCGATCTCGAGCTGACCTGGGCGCCGGTCC
CGAGCCGGATGCCCGGACTCGGCCTGTTCCGCGAGACCGTGGCCGGCCGGACCTATCTGCTGGCCGCCGTGAGCCCGCCG
GCGATCGAGGCCGACGCGGCCGCCCGGCCGGCGCGCGACGTCACCTTCGTCATCGACAATTCCGGCTCGATGTCGGGCGC
CTCGATGCGGCAGGCCAAGGCCGGGCTGCTGGCCGGCCTCGGCCGCCTGAGCCCGCGGGACCGCTTCAACGTCATCCGCT
TCGACGACACCTGGGACGCGCTGCATCCCGAGCCGGTCCCGGCGACGCGGGCGGCCCTGGCCGAGGCTGAAGCCTTCGTC
GCCGCCCTGGAGGCGCGCGGCGGCACCGAGATGCTGGCGCCGCTCAAGGCGGCGCTCGCCGACCCGCACCCGGAGGACGG
GCGCGTCCGCCAGGTCGTGTTCCTCACCGACGGCGCCGTCGGCGACGAGGAGCGGATCTTCGCGGCGATCCACGCGGATC
TCGGGCGCACGCGGCTGTTCATGGTCGGCATCGGCTCGGCGCCGAACGGCCACCTGATGCGCCACGCCGCCGAGATCGGC
CGCGGCAGCTTCACCGAGATCCGCGACCTCGCGCAGGTCGGCGAGCGGACCCGGGCACTGTACGAGAAGCTGGAATCGCC
CGCCGTCACCGACCTGACCGCGACCTTCTCGGTCCCGGGCGTCGCGGTCACGCCGGGCGCGCTGCCCGACCTGTACCGCG
GCGAGCCGCTGGTCTTCGCCGCGCAGCTGCCGGGATCGGCCGAGGAAGCGGCCCGCGGGACCGTGACCGTCTCGGGCCGG
GTGGGCGGCCGGACCTGGACCCGGACGCTGCCGCTCTCCGGAGCGGGTGAGGGCGCCGGCATCTCCAAGGTCTGGGCGCG
TTCCCGGATCGGCGAGACCGAGACGGCGCGCATCACCGGGCGGCTCGGCGCGGACGCGGCCGACGCCACCATCCTGGCGC
TGGCCCTGGAGCACGGCCTGACGACGCGGCTGACCAGCCTCGTGGCCATCGACGCGACCCCGCGCCGCGCGCCGGGCACG
GCCCTCGTCGCCGCCGACCTGCCGCTGAACCTGCCGGCGGGCTGGGACTTCGCCAAGGTGTTCGGCACGGACCGGCCCGG
CGCCGCGCCCGCCGACGACGGGGCGGCCCGGATCGTGCCGATCCGCGCCGACGGCGGGGCGGTCGACCTGCCGCAGACCG
GGGCCGGGATCGTGGCGAAGCTCGGCCTGGGCCTGCTCCTCGCCCTGTTGGGCCTCCTGCTGCGCACCGGCCCGACGATC
GGCGGCCGGCGGACCGGGAACGCGCGATGA

Upstream 100 bases:

>100_bases
AGCCGGGAAAAGGGCGAAGCTTCTCGTGGCGGCGCGGCGGCGGGCGCGGGAGCTTCAGCGACGGGCCGGCCCCGATCCGC
CGGCGCAGGAGGTTTCCCCG

Downstream 100 bases:

>100_bases
GCCGCCGTCCGGGGACCGGACTGGGGAGGGCCCTCGCGGCCCTCCTCACCCTCGCGGGAATCGGGCTGGCGGCGCAGGCC
GCCTGGATCCCCGCCAGGGC

Product: vault protein inter-alpha-trypsin subunit

Products: NA

Alternate protein names: Inter-Alpha-Trypsin Inhibitor Domain-Containing Protein; Vault Protein Inter-Alpha-Trypsin; Vault Protein Inter-Alpha-Trypsin Domain Protein; Cell Wall Anchor Domain-Containing Protein; Von Willebrand Factor Type A Domain-Containing Protein; Vault Protein Inter-Alpha-Trypsin Domain-Containing Protein; Von Willebrand Factor Type A; LPXTG-Motif Cell Wall Anchor Domain-Containing Protein; Transmembrane Protein; LPXTG-Motif Cell Wall Anchor Domain Protein; Vault Protein Inter-Alpha-Trypsin Domain; Inter-Alpha-Trypsin Inhibitor Domain Protein; Von Willebrand Factor; Von Willebrand Factor Type A Domain Protein

Number of amino acids: Translated: 729; Mature: 728

Protein sequence:

>729_residues
MPFFAPRSALEPPRNAALSPLFLALLALLVMLASAHAAPGPARGGLTLRGPSGTAPVEAVQLATDISVDVSGPTARATVT
QAFRNVTAEWVEGTYLYPLPEDAAVDRMKLVVGSRVIIADIRERAAAKRAYEAAKAAGQAAALTAQERPNVFTNAVANIG
PGETVLVQITYQQTIPVSGETRTLRLPLVVAPRYNPAPTSVDAVSLDGPAAAARDPVPDRARISPPVLDPALSAPTNPVA
VTVRLRAGFAVGAVQSATHAIRVIETGPEARTVTLAEGVVPADRDLELTWAPVPSRMPGLGLFRETVAGRTYLLAAVSPP
AIEADAAARPARDVTFVIDNSGSMSGASMRQAKAGLLAGLGRLSPRDRFNVIRFDDTWDALHPEPVPATRAALAEAEAFV
AALEARGGTEMLAPLKAALADPHPEDGRVRQVVFLTDGAVGDEERIFAAIHADLGRTRLFMVGIGSAPNGHLMRHAAEIG
RGSFTEIRDLAQVGERTRALYEKLESPAVTDLTATFSVPGVAVTPGALPDLYRGEPLVFAAQLPGSAEEAARGTVTVSGR
VGGRTWTRTLPLSGAGEGAGISKVWARSRIGETETARITGRLGADAADATILALALEHGLTTRLTSLVAIDATPRRAPGT
ALVAADLPLNLPAGWDFAKVFGTDRPGAAPADDGAARIVPIRADGGAVDLPQTGAGIVAKLGLGLLLALLGLLLRTGPTI
GGRRTGNAR

Sequences:

>Translated_729_residues
MPFFAPRSALEPPRNAALSPLFLALLALLVMLASAHAAPGPARGGLTLRGPSGTAPVEAVQLATDISVDVSGPTARATVT
QAFRNVTAEWVEGTYLYPLPEDAAVDRMKLVVGSRVIIADIRERAAAKRAYEAAKAAGQAAALTAQERPNVFTNAVANIG
PGETVLVQITYQQTIPVSGETRTLRLPLVVAPRYNPAPTSVDAVSLDGPAAAARDPVPDRARISPPVLDPALSAPTNPVA
VTVRLRAGFAVGAVQSATHAIRVIETGPEARTVTLAEGVVPADRDLELTWAPVPSRMPGLGLFRETVAGRTYLLAAVSPP
AIEADAAARPARDVTFVIDNSGSMSGASMRQAKAGLLAGLGRLSPRDRFNVIRFDDTWDALHPEPVPATRAALAEAEAFV
AALEARGGTEMLAPLKAALADPHPEDGRVRQVVFLTDGAVGDEERIFAAIHADLGRTRLFMVGIGSAPNGHLMRHAAEIG
RGSFTEIRDLAQVGERTRALYEKLESPAVTDLTATFSVPGVAVTPGALPDLYRGEPLVFAAQLPGSAEEAARGTVTVSGR
VGGRTWTRTLPLSGAGEGAGISKVWARSRIGETETARITGRLGADAADATILALALEHGLTTRLTSLVAIDATPRRAPGT
ALVAADLPLNLPAGWDFAKVFGTDRPGAAPADDGAARIVPIRADGGAVDLPQTGAGIVAKLGLGLLLALLGLLLRTGPTI
GGRRTGNAR
>Mature_728_residues
PFFAPRSALEPPRNAALSPLFLALLALLVMLASAHAAPGPARGGLTLRGPSGTAPVEAVQLATDISVDVSGPTARATVTQ
AFRNVTAEWVEGTYLYPLPEDAAVDRMKLVVGSRVIIADIRERAAAKRAYEAAKAAGQAAALTAQERPNVFTNAVANIGP
GETVLVQITYQQTIPVSGETRTLRLPLVVAPRYNPAPTSVDAVSLDGPAAAARDPVPDRARISPPVLDPALSAPTNPVAV
TVRLRAGFAVGAVQSATHAIRVIETGPEARTVTLAEGVVPADRDLELTWAPVPSRMPGLGLFRETVAGRTYLLAAVSPPA
IEADAAARPARDVTFVIDNSGSMSGASMRQAKAGLLAGLGRLSPRDRFNVIRFDDTWDALHPEPVPATRAALAEAEAFVA
ALEARGGTEMLAPLKAALADPHPEDGRVRQVVFLTDGAVGDEERIFAAIHADLGRTRLFMVGIGSAPNGHLMRHAAEIGR
GSFTEIRDLAQVGERTRALYEKLESPAVTDLTATFSVPGVAVTPGALPDLYRGEPLVFAAQLPGSAEEAARGTVTVSGRV
GGRTWTRTLPLSGAGEGAGISKVWARSRIGETETARITGRLGADAADATILALALEHGLTTRLTSLVAIDATPRRAPGTA
LVAADLPLNLPAGWDFAKVFGTDRPGAAPADDGAARIVPIRADGGAVDLPQTGAGIVAKLGLGLLLALLGLLLRTGPTIG
GRRTGNAR

Specific function: Unknown

COG id: COG2304

COG function: function code R; Uncharacterized protein containing a von Willebrand factor type A (vWA) domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI38195080, Length=679, Percent_Identity=25.7731958762887, Blast_Score=140, Evalue=5e-33,
Organism=Homo sapiens, GI194306644, Length=679, Percent_Identity=25.7731958762887, Blast_Score=140, Evalue=5e-33,
Organism=Homo sapiens, GI112789550, Length=598, Percent_Identity=23.4113712374582, Blast_Score=136, Evalue=6e-32,
Organism=Homo sapiens, GI210147462, Length=558, Percent_Identity=24.5519713261649, Blast_Score=113, Evalue=6e-25,
Organism=Homo sapiens, GI38348336, Length=339, Percent_Identity=30.3834808259587, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI262050538, Length=330, Percent_Identity=27.5757575757576, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI31542984, Length=330, Percent_Identity=27.5757575757576, Blast_Score=91, Evalue=5e-18,
Organism=Homo sapiens, GI133925809, Length=321, Percent_Identity=24.9221183800623, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI153945711, Length=243, Percent_Identity=25.1028806584362, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI153945780, Length=227, Percent_Identity=25.5506607929515, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI49355778, Length=227, Percent_Identity=25.5506607929515, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI156119625, Length=323, Percent_Identity=24.1486068111455, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI261878618, Length=323, Percent_Identity=24.1486068111455, Blast_Score=77, Evalue=8e-14,
Organism=Homo sapiens, GI261878616, Length=323, Percent_Identity=24.1486068111455, Blast_Score=77, Evalue=8e-14,
Organism=Homo sapiens, GI261878614, Length=323, Percent_Identity=24.1486068111455, Blast_Score=77, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 75532; Mature: 75401

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS50234 VWFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFFAPRSALEPPRNAALSPLFLALLALLVMLASAHAAPGPARGGLTLRGPSGTAPVEAV
CCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCHHHE
QLATDISVDVSGPTARATVTQAFRNVTAEWVEGTYLYPLPEDAAVDRMKLVVGSRVIIAD
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCEEEEHH
IRERAAAKRAYEAAKAAGQAAALTAQERPNVFTNAVANIGPGETVLVQITYQQTIPVSGE
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHCCCCCCEEEEEEEEEEEECCCCC
TRTLRLPLVVAPRYNPAPTSVDAVSLDGPAAAARDPVPDRARISPPVLDPALSAPTNPVA
CEEEEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCEE
VTVRLRAGFAVGAVQSATHAIRVIETGPEARTVTLAEGVVPADRDLELTWAPVPSRMPGL
EEEEEECCEEEHHHHHCCEEEEEEECCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCC
GLFRETVAGRTYLLAAVSPPAIEADAAARPARDVTFVIDNSGSMSGASMRQAKAGLLAGL
HHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
GRLSPRDRFNVIRFDDTWDALHPEPVPATRAALAEAEAFVAALEARGGTEMLAPLKAALA
CCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
DPHPEDGRVRQVVFLTDGAVGDEERIFAAIHADLGRTRLFMVGIGSAPNGHLMRHAAEIG
CCCCCCCCEEEEEEEECCCCCCHHHEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHC
RGSFTEIRDLAQVGERTRALYEKLESPAVTDLTATFSVPGVAVTPGALPDLYRGEPLVFA
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEECCCCCCHHHCCCCEEEE
AQLPGSAEEAARGTVTVSGRVGGRTWTRTLPLSGAGEGAGISKVWARSRIGETETARITG
EECCCCHHHHCCCEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEEE
RLGADAADATILALALEHGLTTRLTSLVAIDATPRRAPGTALVAADLPLNLPAGWDFAKV
ECCCCCHHHHHHHHHHHCCCHHHHHEEEEECCCCCCCCCCEEEEECCCCCCCCCCCHHHH
FGTDRPGAAPADDGAARIVPIRADGGAVDLPQTGAGIVAKLGLGLLLALLGLLLRTGPTI
HCCCCCCCCCCCCCCEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
GGRRTGNAR
CCCCCCCCC
>Mature Secondary Structure 
PFFAPRSALEPPRNAALSPLFLALLALLVMLASAHAAPGPARGGLTLRGPSGTAPVEAV
CCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCHHHE
QLATDISVDVSGPTARATVTQAFRNVTAEWVEGTYLYPLPEDAAVDRMKLVVGSRVIIAD
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCEEEEHH
IRERAAAKRAYEAAKAAGQAAALTAQERPNVFTNAVANIGPGETVLVQITYQQTIPVSGE
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHCCCCCCEEEEEEEEEEEECCCCC
TRTLRLPLVVAPRYNPAPTSVDAVSLDGPAAAARDPVPDRARISPPVLDPALSAPTNPVA
CEEEEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCEE
VTVRLRAGFAVGAVQSATHAIRVIETGPEARTVTLAEGVVPADRDLELTWAPVPSRMPGL
EEEEEECCEEEHHHHHCCEEEEEEECCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCC
GLFRETVAGRTYLLAAVSPPAIEADAAARPARDVTFVIDNSGSMSGASMRQAKAGLLAGL
HHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
GRLSPRDRFNVIRFDDTWDALHPEPVPATRAALAEAEAFVAALEARGGTEMLAPLKAALA
CCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
DPHPEDGRVRQVVFLTDGAVGDEERIFAAIHADLGRTRLFMVGIGSAPNGHLMRHAAEIG
CCCCCCCCEEEEEEEECCCCCCHHHEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHC
RGSFTEIRDLAQVGERTRALYEKLESPAVTDLTATFSVPGVAVTPGALPDLYRGEPLVFA
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEECCCCCCHHHCCCCEEEE
AQLPGSAEEAARGTVTVSGRVGGRTWTRTLPLSGAGEGAGISKVWARSRIGETETARITG
EECCCCHHHHCCCEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEEE
RLGADAADATILALALEHGLTTRLTSLVAIDATPRRAPGTALVAADLPLNLPAGWDFAKV
ECCCCCHHHHHHHHHHHCCCHHHHHEEEEECCCCCCCCCCEEEEECCCCCCCCCCCHHHH
FGTDRPGAAPADDGAARIVPIRADGGAVDLPQTGAGIVAKLGLGLLLALLGLLLRTGPTI
HCCCCCCCCCCCCCCEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
GGRRTGNAR
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA