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The map label for this gene is mtaD [H]

Identifier: 170751533

GI number: 170751533

Start: 5480381

End: 5481922

Strand: Reverse

Name: mtaD [H]

Synonym: Mrad2831_5153

Alternate gene names: 170751533

Gene position: 5481922-5480381 (Counterclockwise)

Preceding gene: 170751534

Following gene: 170751529

Centisome position: 90.2

GC content: 69.58

Gene sequence:

>1542_bases
ATGGCCACATCGCTGATCCGCAGCCGGCGGATGATCACCCGTACCCTCGACCACGATCGCTGGGAGGAGATCGCCGACGG
CGCGGTCCTTCAGAAGGACGGGGTCATCGCGGCGGTCGGCACCTACGCGGACCTGCACGCCCGCTACCCCGACGCCCCGG
TGATCGGCTCCGGCCGCGAGATCCTGCTGCCGGGCTTCGTCAACGGCCACCACCATGTCGGCCTGACGCCGGTGCAGCTC
GGCTCACCCGACATGCCCCTGGAGCTGTGGTTCGTCACCCGCATGGTGGCGCGCAACCTGAACCTCTACCTCGACACCCT
CTACTCGGCCTTCGAGATGGTCGGCTCCGGGATCACCACGGTCCAGCACATCCACGGCTGGATGCCGGGCAGCCTGGAGG
AGGTCGAGGCGCGCTCCAACGAGGTGCTGCGCGCCTATCGCGACATCGGCATGCGGGTCTCGTACTGCTTCGCGGTCCGC
GACCAGAACCGTCTCGTCTACCAGGCCGACATGGATTTCGTGGCGAGCCTGCCGGCGCCGCTGCAGGACCCGATGAAGCG
CTGGTTCGAGCGCTTCCAGATGTCCCTGGAGGACAATTTCTCGCTCTTCCGCAGCCTGCATGCCGGCCAGGAGGGGGCCT
CGCGCGCCAAGATCCAGCTGGCGCCCGCCAACCTGCACTGGTGCTCCGACGCGGCCCTCGAAGGGCTCGCCGGACTGTCC
GAATCCTACGACGTGCCGATGCACATGCATCTCGTCGAGACCGCCTACCAGAAGGCCTACGCGGAGAAGCGCGGCGGCGG
TACCGCCCTCGAGTACCTCGACCGGTTCGGGATGCTCGGTCCGCGCCTGACGCTCGGCCACGGCGTCTGGCTCAACGAAT
CCGACATCGAGCGGGTGGCGGCGACCGGCACCTGCATCTGCCACAATTGCTCGTCGAACTTCCGGCTGCGCTCCGGCGTG
GCGGCGCTCAACCGGTTCGAGGCGAAGGGCATCAACACGGCGATCGGCCTCGACGAGGCCGGCATCAACGACGACCGCGA
CATGCTCCAGGAGATGCGCCTCGTGCTGCGCGCCCACCGGGTGCCCGGCATGGACGAGGCCGAGGTGCCGAGCATGGCGC
AGGTGCTTCGGATGGCGACCGTCGGCGGCGCCCGCACCACCCCCTACGGCGACGGCCTCGGCACGATCGAGGTCGGCAAG
GGCGCCGACCTCGTCCTGATCGACTGGGACCAGATCGCCTACCCGTATCTCGACCCGGAGACGCCGCTCCTCGACGCGGT
GATCCAGCGGGCCAAGACCGGCGGCGTCACCGCGGTGCTATGCGAGGGCGAGGTGCTCTACGCGGACGGGCGGTTCACGC
GGGTCGACCGCGACGCCGCCCTGAAGGCGCTCCACGACGACCTGTCGCGGGCGCTCTCGGACGACGAGGTCGAGCGGCGC
CAGCTCTCGAAGGCGCTGCTCCCCCACGCGCGGCGCTTCTACGCCGACTACATCGACCCGTCGCGGCACGAGCCGTTCTA
CCGCCCGAGCTCGCGCGTCTGA

Upstream 100 bases:

>100_bases
TGCGGCGTCACCTCACCGAGCTGCTGCGCGACGAGGTCGACCGGGCCTTCGCCGAGCAGGAAGCGCTCGTCTGACCCCCT
CCCCCAACACGGACACGACC

Downstream 100 bases:

>100_bases
CGGCGCGGGCCCGGGCCGGTCCTCAGCGGACCAGGCAGGGCTTCTTGTTGTCGAAGGTCCAGCCGGGGATCAGGAACTGC
ATGGCGGCCGCGTCGTCGCG

Product: amidohydrolase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MATSLIRSRRMITRTLDHDRWEEIADGAVLQKDGVIAAVGTYADLHARYPDAPVIGSGREILLPGFVNGHHHVGLTPVQL
GSPDMPLELWFVTRMVARNLNLYLDTLYSAFEMVGSGITTVQHIHGWMPGSLEEVEARSNEVLRAYRDIGMRVSYCFAVR
DQNRLVYQADMDFVASLPAPLQDPMKRWFERFQMSLEDNFSLFRSLHAGQEGASRAKIQLAPANLHWCSDAALEGLAGLS
ESYDVPMHMHLVETAYQKAYAEKRGGGTALEYLDRFGMLGPRLTLGHGVWLNESDIERVAATGTCICHNCSSNFRLRSGV
AALNRFEAKGINTAIGLDEAGINDDRDMLQEMRLVLRAHRVPGMDEAEVPSMAQVLRMATVGGARTTPYGDGLGTIEVGK
GADLVLIDWDQIAYPYLDPETPLLDAVIQRAKTGGVTAVLCEGEVLYADGRFTRVDRDAALKALHDDLSRALSDDEVERR
QLSKALLPHARRFYADYIDPSRHEPFYRPSSRV

Sequences:

>Translated_513_residues
MATSLIRSRRMITRTLDHDRWEEIADGAVLQKDGVIAAVGTYADLHARYPDAPVIGSGREILLPGFVNGHHHVGLTPVQL
GSPDMPLELWFVTRMVARNLNLYLDTLYSAFEMVGSGITTVQHIHGWMPGSLEEVEARSNEVLRAYRDIGMRVSYCFAVR
DQNRLVYQADMDFVASLPAPLQDPMKRWFERFQMSLEDNFSLFRSLHAGQEGASRAKIQLAPANLHWCSDAALEGLAGLS
ESYDVPMHMHLVETAYQKAYAEKRGGGTALEYLDRFGMLGPRLTLGHGVWLNESDIERVAATGTCICHNCSSNFRLRSGV
AALNRFEAKGINTAIGLDEAGINDDRDMLQEMRLVLRAHRVPGMDEAEVPSMAQVLRMATVGGARTTPYGDGLGTIEVGK
GADLVLIDWDQIAYPYLDPETPLLDAVIQRAKTGGVTAVLCEGEVLYADGRFTRVDRDAALKALHDDLSRALSDDEVERR
QLSKALLPHARRFYADYIDPSRHEPFYRPSSRV
>Mature_512_residues
ATSLIRSRRMITRTLDHDRWEEIADGAVLQKDGVIAAVGTYADLHARYPDAPVIGSGREILLPGFVNGHHHVGLTPVQLG
SPDMPLELWFVTRMVARNLNLYLDTLYSAFEMVGSGITTVQHIHGWMPGSLEEVEARSNEVLRAYRDIGMRVSYCFAVRD
QNRLVYQADMDFVASLPAPLQDPMKRWFERFQMSLEDNFSLFRSLHAGQEGASRAKIQLAPANLHWCSDAALEGLAGLSE
SYDVPMHMHLVETAYQKAYAEKRGGGTALEYLDRFGMLGPRLTLGHGVWLNESDIERVAATGTCICHNCSSNFRLRSGVA
ALNRFEAKGINTAIGLDEAGINDDRDMLQEMRLVLRAHRVPGMDEAEVPSMAQVLRMATVGGARTTPYGDGLGTIEVGKG
ADLVLIDWDQIAYPYLDPETPLLDAVIQRAKTGGVTAVLCEGEVLYADGRFTRVDRDAALKALHDDLSRALSDDEVERRQ
LSKALLPHARRFYADYIDPSRHEPFYRPSSRV

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Escherichia coli, GI87082177, Length=444, Percent_Identity=24.0990990990991, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 57044; Mature: 56912

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSLIRSRRMITRTLDHDRWEEIADGAVLQKDGVIAAVGTYADLHARYPDAPVIGSGRE
CCHHHHHHHHHHHHHHCHHHHHHHHCCCEEECCCEEEEECCHHHHHCCCCCCCEECCCCE
ILLPGFVNGHHHVGLTPVQLGSPDMPLELWFVTRMVARNLNLYLDTLYSAFEMVGSGITT
EEECCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHH
VQHIHGWMPGSLEEVEARSNEVLRAYRDIGMRVSYCFAVRDQNRLVYQADMDFVASLPAP
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCEEEEECCHHHHHCCCC
LQDPMKRWFERFQMSLEDNFSLFRSLHAGQEGASRAKIQLAPANLHWCSDAALEGLAGLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEECCHHHHHHHHCCC
ESYDVPMHMHLVETAYQKAYAEKRGGGTALEYLDRFGMLGPRLTLGHGVWLNESDIERVA
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEECCCEECCHHHHHHHH
ATGTCICHNCSSNFRLRSGVAALNRFEAKGINTAIGLDEAGINDDRDMLQEMRLVLRAHR
HCCCEEEECCCCCCEEHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHC
VPGMDEAEVPSMAQVLRMATVGGARTTPYGDGLGTIEVGKGADLVLIDWDQIAYPYLDPE
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEEHHHCCCCCCCCC
TPLLDAVIQRAKTGGVTAVLCEGEVLYADGRFTRVDRDAALKALHDDLSRALSDDEVERR
CHHHHHHHHHHCCCCEEEEEECCEEEEECCCEEECCHHHHHHHHHHHHHHHHCCHHHHHH
QLSKALLPHARRFYADYIDPSRHEPFYRPSSRV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ATSLIRSRRMITRTLDHDRWEEIADGAVLQKDGVIAAVGTYADLHARYPDAPVIGSGRE
CHHHHHHHHHHHHHHCHHHHHHHHCCCEEECCCEEEEECCHHHHHCCCCCCCEECCCCE
ILLPGFVNGHHHVGLTPVQLGSPDMPLELWFVTRMVARNLNLYLDTLYSAFEMVGSGITT
EEECCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHH
VQHIHGWMPGSLEEVEARSNEVLRAYRDIGMRVSYCFAVRDQNRLVYQADMDFVASLPAP
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCEEEEECCHHHHHCCCC
LQDPMKRWFERFQMSLEDNFSLFRSLHAGQEGASRAKIQLAPANLHWCSDAALEGLAGLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEECCHHHHHHHHCCC
ESYDVPMHMHLVETAYQKAYAEKRGGGTALEYLDRFGMLGPRLTLGHGVWLNESDIERVA
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEECCCEECCHHHHHHHH
ATGTCICHNCSSNFRLRSGVAALNRFEAKGINTAIGLDEAGINDDRDMLQEMRLVLRAHR
HCCCEEEECCCCCCEEHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHC
VPGMDEAEVPSMAQVLRMATVGGARTTPYGDGLGTIEVGKGADLVLIDWDQIAYPYLDPE
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEEHHHCCCCCCCCC
TPLLDAVIQRAKTGGVTAVLCEGEVLYADGRFTRVDRDAALKALHDDLSRALSDDEVERR
CHHHHHHHHHHCCCCEEEEEECCEEEEECCCEEECCHHHHHHHHHHHHHHHHCCHHHHHH
QLSKALLPHARRFYADYIDPSRHEPFYRPSSRV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]