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The map label for this gene is selA [H]

Identifier: 170751523

GI number: 170751523

Start: 5468545

End: 5469987

Strand: Direct

Name: selA [H]

Synonym: Mrad2831_5143

Alternate gene names: 170751523

Gene position: 5468545-5469987 (Clockwise)

Preceding gene: 170751519

Following gene: 170751524

Centisome position: 89.98

GC content: 76.16

Gene sequence:

>1443_bases
ATGAACGGACCCGCCCCCACCCCTCAGGCCGTCGACCCGGCGCCGTCCCCGCGCCGGATTCCCTCGGTCGAGCGCCTCGT
CGGCGGCGCGCCGCCCGCCGATCTCGAGACCTACGGGCGGACGGCCTTCACGGACGCGATCCGGGCGGTGGTGGCCGGGC
TCCGGGCGGGGGGCGGTCCCGTCCCGGACGCGGCGGCGATCCGGGCGGCGGCGTCGGCGCGCCTCGCCGCCGAGCGGCGC
CCGTCCCTGCGGCCGGTCCTCAACCTGACCGGGACGGTTCTGCACACCAATCTCGGCCGCGCCCTGCTGCCCCGCTCGGC
CGCGGAGGCGGTGGCCGCCGTGATGGTGCAGGCGAGCAACCTCGAATTCGATCTCGAGACCGGCGCCCGCGGCGAGCGGG
ACGATCATGTCGAGGCCCTGATCTGCCGCCTGACCGGCGCCGAGGCCGCGGTCGTCGTCAACAACAACGCGGCCGCCGTC
CTGCTGGTGCTGAACGCGCTCGCCATGCGCAGGGAGGTGGTGGTCTCCCGCGGCGAGCTCGTGGAGATCGGCGGCTCGTT
CCGGGTGCCGGACGTGATGGTGCGGGCCGGTTGCCGCCTGCGCGAGGTCGGCACCACGAACCGTACCCACCTGCGCGACT
ACGCGGAGGCCCTCGGGCCCCGCACCGGCCTCGTGATGAAGGTGCACCCGAGCAACTACGCCATCGCGGGCTTCACCGCG
GCGGCGGATCCCGTCGCCCTCCACGCCCTCTGCCGGGAGCGCGGCGTGCCGCTGGCGGACGATCTCGGAAGCGGCAGCCT
CGTCGACCTCGCGGCCCACGGGCTGCCCCCCGAGCCCACGGTCCGCGCCGCCCTGGAGCGGGCCGACGTCGTCACCTTCA
GCGGCGACAAATTGCTCGGCGCGGTCCAGTGCGGCATCGTGGCGGGGCGGAGGGACCTGATCGCCCGCGTGCGCAAGAAC
CCGCTGAAGCGGGCCCTGCGCGTCGACAAGATGACCTACGCGGCGCTCGAGGCCGTGCTGCGGCTCTACCTGCACCCCGA
GCGGCTGCGCGCGGAGCTGCCGACCCTGCGGCTCCTGACCCGCGCGCGCGACGCGATCGCCGCGCAGGCCGAGCGCCTCG
CCCCCGCGGTGGCGGAGCGGCTCGCCGGCCGCGCCACGGTCACGGTCGCCGACTGCATCAGCCAGATCGGATCCGGCGCC
CTGCCGGTGGAGACCCTGCCCAGCGCCGCCCTGGTCCTGACGCCGGTCTCCGCGGGCGGCCGCGGCGCGGGCGGGCGGTG
CCGGCGGCTCGCCGAGGATCTGCGCCGGCTCCCGGTGCCGGTGATCGGCCGGATCAGCGACGAGGCCGTCCGCCTGGATC
TCCGGACGCTCGAGGACGAGCCGGGCTTCCTCGACGCACTGGCGGCGCTCCCGCCCGTCGTGGACGGGAGACGAACCCCA
TAG

Upstream 100 bases:

>100_bases
TCTGCCCTTACCGTCGGGCCGGGACCGGAACAACCTGCGCGAATTATCCGCGCGTCGACGGGCTGGCTCCGTGCAGCGGG
ATGGTTATCTCTGGCCTGAC

Downstream 100 bases:

>100_bases
GGTTGTTAAGAGAACGGGCCCGACGCTCGGAGCTTGCGCGCCGGCATCCCGTGTTATGGTATGATGACGAACCCGCGGTC
GCGGTCGAGTGTGGCGGTGC

Product: L-seryl-tRNA(Sec) selenium transferase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MNGPAPTPQAVDPAPSPRRIPSVERLVGGAPPADLETYGRTAFTDAIRAVVAGLRAGGGPVPDAAAIRAAASARLAAERR
PSLRPVLNLTGTVLHTNLGRALLPRSAAEAVAAVMVQASNLEFDLETGARGERDDHVEALICRLTGAEAAVVVNNNAAAV
LLVLNALAMRREVVVSRGELVEIGGSFRVPDVMVRAGCRLREVGTTNRTHLRDYAEALGPRTGLVMKVHPSNYAIAGFTA
AADPVALHALCRERGVPLADDLGSGSLVDLAAHGLPPEPTVRAALERADVVTFSGDKLLGAVQCGIVAGRRDLIARVRKN
PLKRALRVDKMTYAALEAVLRLYLHPERLRAELPTLRLLTRARDAIAAQAERLAPAVAERLAGRATVTVADCISQIGSGA
LPVETLPSAALVLTPVSAGGRGAGGRCRRLAEDLRRLPVPVIGRISDEAVRLDLRTLEDEPGFLDALAALPPVVDGRRTP

Sequences:

>Translated_480_residues
MNGPAPTPQAVDPAPSPRRIPSVERLVGGAPPADLETYGRTAFTDAIRAVVAGLRAGGGPVPDAAAIRAAASARLAAERR
PSLRPVLNLTGTVLHTNLGRALLPRSAAEAVAAVMVQASNLEFDLETGARGERDDHVEALICRLTGAEAAVVVNNNAAAV
LLVLNALAMRREVVVSRGELVEIGGSFRVPDVMVRAGCRLREVGTTNRTHLRDYAEALGPRTGLVMKVHPSNYAIAGFTA
AADPVALHALCRERGVPLADDLGSGSLVDLAAHGLPPEPTVRAALERADVVTFSGDKLLGAVQCGIVAGRRDLIARVRKN
PLKRALRVDKMTYAALEAVLRLYLHPERLRAELPTLRLLTRARDAIAAQAERLAPAVAERLAGRATVTVADCISQIGSGA
LPVETLPSAALVLTPVSAGGRGAGGRCRRLAEDLRRLPVPVIGRISDEAVRLDLRTLEDEPGFLDALAALPPVVDGRRTP
>Mature_480_residues
MNGPAPTPQAVDPAPSPRRIPSVERLVGGAPPADLETYGRTAFTDAIRAVVAGLRAGGGPVPDAAAIRAAASARLAAERR
PSLRPVLNLTGTVLHTNLGRALLPRSAAEAVAAVMVQASNLEFDLETGARGERDDHVEALICRLTGAEAAVVVNNNAAAV
LLVLNALAMRREVVVSRGELVEIGGSFRVPDVMVRAGCRLREVGTTNRTHLRDYAEALGPRTGLVMKVHPSNYAIAGFTA
AADPVALHALCRERGVPLADDLGSGSLVDLAAHGLPPEPTVRAALERADVVTFSGDKLLGAVQCGIVAGRRDLIARVRKN
PLKRALRVDKMTYAALEAVLRLYLHPERLRAELPTLRLLTRARDAIAAQAERLAPAVAERLAGRATVTVADCISQIGSGA
LPVETLPSAALVLTPVSAGGRGAGGRCRRLAEDLRRLPVPVIGRISDEAVRLDLRTLEDEPGFLDALAALPPVVDGRRTP

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=455, Percent_Identity=53.8461538461538, Blast_Score=412, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 50408; Mature: 50408

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGPAPTPQAVDPAPSPRRIPSVERLVGGAPPADLETYGRTAFTDAIRAVVAGLRAGGGP
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCC
VPDAAAIRAAASARLAAERRPSLRPVLNLTGTVLHTNLGRALLPRSAAEAVAAVMVQASN
CCHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHCCCHHHCCHHHHHHHHHHHHHHCC
LEFDLETGARGERDDHVEALICRLTGAEAAVVVNNNAAAVLLVLNALAMRREVVVSRGEL
CEEEECCCCCCCCCHHHHHHHHEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCE
VEIGGSFRVPDVMVRAGCRLREVGTTNRTHLRDYAEALGPRTGLVMKVHPSNYAIAGFTA
EEECCCCCCCHHHHHCCCCEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECC
AADPVALHALCRERGVPLADDLGSGSLVDLAAHGLPPEPTVRAALERADVVTFSGDKLLG
CCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHCCEEEECCCCHHH
AVQCGIVAGRRDLIARVRKNPLKRALRVDKMTYAALEAVLRLYLHPERLRAELPTLRLLT
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHH
RARDAIAAQAERLAPAVAERLAGRATVTVADCISQIGSGALPVETLPSAALVLTPVSAGG
HHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCHHHCCCCEEEEEECCCCC
RGAGGRCRRLAEDLRRLPVPVIGRISDEAVRLDLRTLEDEPGFLDALAALPPVVDGRRTP
CCCCHHHHHHHHHHHHCCCCCEECCCCHHHEEEHHHCCCCCCHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNGPAPTPQAVDPAPSPRRIPSVERLVGGAPPADLETYGRTAFTDAIRAVVAGLRAGGGP
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCC
VPDAAAIRAAASARLAAERRPSLRPVLNLTGTVLHTNLGRALLPRSAAEAVAAVMVQASN
CCHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHCCCHHHCCHHHHHHHHHHHHHHCC
LEFDLETGARGERDDHVEALICRLTGAEAAVVVNNNAAAVLLVLNALAMRREVVVSRGEL
CEEEECCCCCCCCCHHHHHHHHEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCE
VEIGGSFRVPDVMVRAGCRLREVGTTNRTHLRDYAEALGPRTGLVMKVHPSNYAIAGFTA
EEECCCCCCCHHHHHCCCCEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECC
AADPVALHALCRERGVPLADDLGSGSLVDLAAHGLPPEPTVRAALERADVVTFSGDKLLG
CCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHCCEEEECCCCHHH
AVQCGIVAGRRDLIARVRKNPLKRALRVDKMTYAALEAVLRLYLHPERLRAELPTLRLLT
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHH
RARDAIAAQAERLAPAVAERLAGRATVTVADCISQIGSGALPVETLPSAALVLTPVSAGG
HHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCHHHCCCCEEEEEECCCCC
RGAGGRCRRLAEDLRRLPVPVIGRISDEAVRLDLRTLEDEPGFLDALAALPPVVDGRRTP
CCCCHHHHHHHHHHHHCCCCCEECCCCHHHEEEHHHCCCCCCHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA