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The map label for this gene is cimH [H]

Identifier: 170751470

GI number: 170751470

Start: 5409292

End: 5410623

Strand: Direct

Name: cimH [H]

Synonym: Mrad2831_5090

Alternate gene names: 170751470

Gene position: 5409292-5410623 (Clockwise)

Preceding gene: 170751469

Following gene: 170751471

Centisome position: 89.0

GC content: 67.42

Gene sequence:

>1332_bases
GTGGAGAACGGGCGCGCGGCCCGGTTCTGGCCGGACGTCTGGTGGCGCCTGATCGACTTCAAGATCGGCATCATACCGCT
CCCGATCTTCGTCATTCTGGCGATCCTCCTCACCGTCCTGGTTCAGGAGGGCGAGATCAAGCCCGACGGGCCGACCATGA
TCGCCGTGCTGGTGATGGGCGGCTTCACCTGCGCGGAGATCGGCAAGCGGATCCCCATCCTGAAGAACATCGGTGCCGGC
GCGATCTTCGCGACCTTCATCCCGTCGGCGCTGGTCTACTACGCGCTGGTGCCGCCGCAGATGGTGAAGGCGATCACCGA
TTTCACCAAGTTCACCAACTTCCTCTACATCTACATCGCCACGATCATCGTCGGCTCGATCCTCGGCATGGACCGCGAGG
TCCTGATCAAGGGCTTCCTCAAGATCTTCGCGCCGCTCGCCCTCGGCTCGGTGGCGGCGGCCCTGGTCGGCACGCTGGTC
GGCACGCTGCTCGGCCTCGGCCCCTACAAGACGTTCTTCTTCATCGTCGTGCCGATCATGGCCGGCGGCGTCGGGGAGGG
GGCGATTCCGCTCTCCATCGGCTACGCGGCGATCCTCGGCCTGCAGCAGGGCGTGGTCTTCGCCCAGGTGCTGCCGCCGG
TGATGCTGGGCTCCCTGACCGCGATCATCCTGTCGGGAGCCCTGAACTCCGTCGGCAAGCGCTACCCGCACCTCACCGGC
GAGGGCCGTCTCCAGCCCGATTCCGACGGCATCAAGTCGAGCGACGCCCAGGCCAGGGCCGAGGCCGCCAAGGGCCAGAT
CGACCCCGCGACGATCGGCGCGGCCGGGCTCACGGCGATCACCCTCTACCTGCTCGGTGTCATGGCCCATCACCTCGTCG
GCCTGCCGGCGCCGGTGGCGATGCTGTTCCTCGCCGTCCTGGCGAAGCTCGCCAGCGCGGTGTCGCCCCACCTCCAGGCC
GGCGGCTTCGTCGTCTACAAGTTCGTGCAGGTCTCGATGACCTACCCGCTGCTCTTCGCCATCGGCGTGGCGCTCACCCC
CTGGCACGAGCTGATGGCCGCCTTCACCCTGGTCAATCTGATCACGATCGTGTCGACCGTCGTGACGCTGATGGCCGTCG
GCTTCTTCGTCGGCCGCTGGCTCGGGATGTACCCGATCGAGACCGCCATCGTGAACGCCTGTCACAGCGGTCAGGGCGGC
ACCGGCGACGTGGCGATCCTCACGGCGGCGAACCGCATGGCGCTGATGCCCTTCGCGCAGATCGCCACCCGCATCGGCGG
CGCGCTGACCGTGACCGGCACGATCGTCGCCATGAAGTGGATCGGTGCCTGA

Upstream 100 bases:

>100_bases
AGGGCGCGGCGAAACGGCCCGCAAGCGGTCAGAGATCCGGGGGGACGCCATGACCAGCACCGCATCACCGAGCCCGATCC
CCTCGCCGGCAGAGGGGCGG

Downstream 100 bases:

>100_bases
TGGGCACCCGGAAAGGACGTCGTCATGGCCGGTGATCCCGGGGCCGTCGGGGCCACGCTCCAGTCGAGGATCGGCGCGAT
CCTCCGCTCGACGAGCGGCA

Product: citrate carrier protein

Products: NA

Alternate protein names: Citrate/malate-proton symporter [H]

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MENGRAARFWPDVWWRLIDFKIGIIPLPIFVILAILLTVLVQEGEIKPDGPTMIAVLVMGGFTCAEIGKRIPILKNIGAG
AIFATFIPSALVYYALVPPQMVKAITDFTKFTNFLYIYIATIIVGSILGMDREVLIKGFLKIFAPLALGSVAAALVGTLV
GTLLGLGPYKTFFFIVVPIMAGGVGEGAIPLSIGYAAILGLQQGVVFAQVLPPVMLGSLTAIILSGALNSVGKRYPHLTG
EGRLQPDSDGIKSSDAQARAEAAKGQIDPATIGAAGLTAITLYLLGVMAHHLVGLPAPVAMLFLAVLAKLASAVSPHLQA
GGFVVYKFVQVSMTYPLLFAIGVALTPWHELMAAFTLVNLITIVSTVVTLMAVGFFVGRWLGMYPIETAIVNACHSGQGG
TGDVAILTAANRMALMPFAQIATRIGGALTVTGTIVAMKWIGA

Sequences:

>Translated_443_residues
MENGRAARFWPDVWWRLIDFKIGIIPLPIFVILAILLTVLVQEGEIKPDGPTMIAVLVMGGFTCAEIGKRIPILKNIGAG
AIFATFIPSALVYYALVPPQMVKAITDFTKFTNFLYIYIATIIVGSILGMDREVLIKGFLKIFAPLALGSVAAALVGTLV
GTLLGLGPYKTFFFIVVPIMAGGVGEGAIPLSIGYAAILGLQQGVVFAQVLPPVMLGSLTAIILSGALNSVGKRYPHLTG
EGRLQPDSDGIKSSDAQARAEAAKGQIDPATIGAAGLTAITLYLLGVMAHHLVGLPAPVAMLFLAVLAKLASAVSPHLQA
GGFVVYKFVQVSMTYPLLFAIGVALTPWHELMAAFTLVNLITIVSTVVTLMAVGFFVGRWLGMYPIETAIVNACHSGQGG
TGDVAILTAANRMALMPFAQIATRIGGALTVTGTIVAMKWIGA
>Mature_443_residues
MENGRAARFWPDVWWRLIDFKIGIIPLPIFVILAILLTVLVQEGEIKPDGPTMIAVLVMGGFTCAEIGKRIPILKNIGAG
AIFATFIPSALVYYALVPPQMVKAITDFTKFTNFLYIYIATIIVGSILGMDREVLIKGFLKIFAPLALGSVAAALVGTLV
GTLLGLGPYKTFFFIVVPIMAGGVGEGAIPLSIGYAAILGLQQGVVFAQVLPPVMLGSLTAIILSGALNSVGKRYPHLTG
EGRLQPDSDGIKSSDAQARAEAAKGQIDPATIGAAGLTAITLYLLGVMAHHLVGLPAPVAMLFLAVLAKLASAVSPHLQA
GGFVVYKFVQVSMTYPLLFAIGVALTPWHELMAAFTLVNLITIVSTVVTLMAVGFFVGRWLGMYPIETAIVNACHSGQGG
TGDVAILTAANRMALMPFAQIATRIGGALTVTGTIVAMKWIGA

Specific function: Proton motive force-driven secondary transporter that catalyzes the uptake of both citrate and malate. Appears to be an electroneutral proton-solute symporter; the number of protons transported is equal to the valence of the transported anions. Is strictl

COG id: COG3493

COG function: function code C; Na+/citrate symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:citrate (SCF) symporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004679
- InterPro:   IPR018025 [H]

Pfam domain/function: PF03390 2HCT [H]

EC number: NA

Molecular weight: Translated: 46516; Mature: 46516

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCEEEHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHCCCEEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377; 11566984 [H]