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The map label for this gene is ycgM [C]

Identifier: 170751450

GI number: 170751450

Start: 5385127

End: 5386011

Strand: Reverse

Name: ycgM [C]

Synonym: Mrad2831_5069

Alternate gene names: 170751450

Gene position: 5386011-5385127 (Counterclockwise)

Preceding gene: 170751452

Following gene: 170751449

Centisome position: 88.62

GC content: 70.73

Gene sequence:

>885_bases
ATGAAGCTCTTCCGGCACGGCCCGAGCGGCGACGAGAAGCCCGGCCTCGTGGATGCCAGCGGGGGGCTGCGCGACCTGTC
GGGCATCGTGCGCGACATCGCCGGGCCGGCCCTCGCGCCCGACTCGCTCGCGCGGCTGCGCGCGCTGGATCCCGAGACCC
TGCCGAAGCTGCCTCCGGACGTGCGCCTCGGCCCCTGCGTCGGCGGCACCCGGAACGTCGTCGCCATCGGCCTGAACTTC
GCCGATCACGCCGCCGAGACCGGCTCGCCGATCCCCGCGGAGCCGATCATCTTCAACAAAGCCCCGTCCAGCCTGTGCGG
GCCGAACGACACGGTCATCATCCCGAAGGGGTCGCACAGCACCGACTGGGAGGTGGAGCTCGCCGTGGTGATCGGGCGGC
GCGCCAGCTACGTCCACGCCAACGAGGCGCTGAGCTACGTGGCGGGCGCCTGCATCTGCAACGACGTCTCCGAGCGCGAA
TGGCAGATGAACCGCGGTCCGACCTGGACGAAGGGCAAGAGCGCGCCGACCTTCGGCCCCCTCGGGCCCTGGCTGGTGAC
GCTCGACGAGATTCCCGACCTGAAGAACCTCGCCATGAGCCTCGACGTGAACGGCGAGCGCCGGCAGACCGGCTCGACCG
CCACGATGATCTTCGACGTTCCCCAGCTCGTCGCCTACACGTCGCACTTCATGCTGCTGGAGCCGGGCGACGTGATCACC
ACCGGCACGCCGCCGGGCGTCGGCCTCGGCATGAAGCCGCCGCGCTACCTCAAGGCCGGGGACGAGATGGTCCTGCGCAT
CGACCGGCTCGGCGAGCAGCGCCAGAAGGTCATCGCGTTCGACGACTGGACCGCCAAGGTCTCGGCCGGGGAGCCGACGG
ACTGA

Upstream 100 bases:

>100_bases
CGGACCCGTAGCCGCGGCCGGCCTTGCACCCGGGTCGAGGCCCGGCCATGGTCCCGGCGTCCGGCGCAGACCGGTTCAGG
GAAGGATGAGGAGTGCGACC

Downstream 100 bases:

>100_bases
CAGGCTGGGCCGCCGCCTGCGCCCGGGCGGCGGCCTGTTCTCCGGGACTCCCCACCGATATCGGTGATCGCCTGACGCCG
GGTCCGGACGGGGTTTCTAC

Product: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MKLFRHGPSGDEKPGLVDASGGLRDLSGIVRDIAGPALAPDSLARLRALDPETLPKLPPDVRLGPCVGGTRNVVAIGLNF
ADHAAETGSPIPAEPIIFNKAPSSLCGPNDTVIIPKGSHSTDWEVELAVVIGRRASYVHANEALSYVAGACICNDVSERE
WQMNRGPTWTKGKSAPTFGPLGPWLVTLDEIPDLKNLAMSLDVNGERRQTGSTATMIFDVPQLVAYTSHFMLLEPGDVIT
TGTPPGVGLGMKPPRYLKAGDEMVLRIDRLGEQRQKVIAFDDWTAKVSAGEPTD

Sequences:

>Translated_294_residues
MKLFRHGPSGDEKPGLVDASGGLRDLSGIVRDIAGPALAPDSLARLRALDPETLPKLPPDVRLGPCVGGTRNVVAIGLNF
ADHAAETGSPIPAEPIIFNKAPSSLCGPNDTVIIPKGSHSTDWEVELAVVIGRRASYVHANEALSYVAGACICNDVSERE
WQMNRGPTWTKGKSAPTFGPLGPWLVTLDEIPDLKNLAMSLDVNGERRQTGSTATMIFDVPQLVAYTSHFMLLEPGDVIT
TGTPPGVGLGMKPPRYLKAGDEMVLRIDRLGEQRQKVIAFDDWTAKVSAGEPTD
>Mature_294_residues
MKLFRHGPSGDEKPGLVDASGGLRDLSGIVRDIAGPALAPDSLARLRALDPETLPKLPPDVRLGPCVGGTRNVVAIGLNF
ADHAAETGSPIPAEPIIFNKAPSSLCGPNDTVIIPKGSHSTDWEVELAVVIGRRASYVHANEALSYVAGACICNDVSERE
WQMNRGPTWTKGKSAPTFGPLGPWLVTLDEIPDLKNLAMSLDVNGERRQTGSTATMIFDVPQLVAYTSHFMLLEPGDVIT
TGTPPGVGLGMKPPRYLKAGDEMVLRIDRLGEQRQKVIAFDDWTAKVSAGEPTD

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=239, Percent_Identity=48.1171548117155, Blast_Score=213, Evalue=1e-55,
Organism=Homo sapiens, GI40786394, Length=239, Percent_Identity=46.8619246861925, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI215422413, Length=181, Percent_Identity=37.5690607734807, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI66348062, Length=181, Percent_Identity=37.5690607734807, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI13654274, Length=181, Percent_Identity=37.5690607734807, Blast_Score=129, Evalue=3e-30,
Organism=Escherichia coli, GI1787428, Length=203, Percent_Identity=39.4088669950739, Blast_Score=125, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17557057, Length=188, Percent_Identity=35.6382978723404, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324161, Length=218, Percent_Identity=27.9816513761468, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28572127, Length=291, Percent_Identity=37.1134020618557, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24663695, Length=238, Percent_Identity=35.7142857142857, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI28571789, Length=182, Percent_Identity=37.3626373626374, Blast_Score=123, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 31392; Mature: 31392

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFRHGPSGDEKPGLVDASGGLRDLSGIVRDIAGPALAPDSLARLRALDPETLPKLPPD
CCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHCCCCCCC
VRLGPCVGGTRNVVAIGLNFADHAAETGSPIPAEPIIFNKAPSSLCGPNDTVIIPKGSHS
CEECCCCCCCCCEEEEECCCHHHHHHCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCCC
TDWEVELAVVIGRRASYVHANEALSYVAGACICNDVSEREWQMNRGPTWTKGKSAPTFGP
CCCEEEEEEEECCCCCEEEHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCC
LGPWLVTLDEIPDLKNLAMSLDVNGERRQTGSTATMIFDVPQLVAYTSHFMLLEPGDVIT
CCCEEEEHHHCCCHHHEEEEECCCCCCCCCCCEEEEEEEHHHHHHHHCCEEEECCCCEEE
TGTPPGVGLGMKPPRYLKAGDEMVLRIDRLGEQRQKVIAFDDWTAKVSAGEPTD
CCCCCCCCCCCCCCHHHCCCCCEEEEHHHHCCCCCEEEEEECCEEEECCCCCCC
>Mature Secondary Structure
MKLFRHGPSGDEKPGLVDASGGLRDLSGIVRDIAGPALAPDSLARLRALDPETLPKLPPD
CCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHCCCCCCC
VRLGPCVGGTRNVVAIGLNFADHAAETGSPIPAEPIIFNKAPSSLCGPNDTVIIPKGSHS
CEECCCCCCCCCEEEEECCCHHHHHHCCCCCCCCCEEEECCCCCCCCCCCEEEEECCCCC
TDWEVELAVVIGRRASYVHANEALSYVAGACICNDVSEREWQMNRGPTWTKGKSAPTFGP
CCCEEEEEEEECCCCCEEEHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCC
LGPWLVTLDEIPDLKNLAMSLDVNGERRQTGSTATMIFDVPQLVAYTSHFMLLEPGDVIT
CCCEEEEHHHCCCHHHEEEEECCCCCCCCCCCEEEEEEEHHHHHHHHCCEEEECCCCEEE
TGTPPGVGLGMKPPRYLKAGDEMVLRIDRLGEQRQKVIAFDDWTAKVSAGEPTD
CCCCCCCCCCCCCCHHHCCCCCEEEEHHHHCCCCCEEEEEECCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA