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The map label for this gene is 170751395

Identifier: 170751395

GI number: 170751395

Start: 5333332

End: 5333772

Strand: Reverse

Name: 170751395

Synonym: Mrad2831_5014

Alternate gene names: NA

Gene position: 5333772-5333332 (Counterclockwise)

Preceding gene: 170751397

Following gene: 170751393

Centisome position: 87.76

GC content: 70.52

Gene sequence:

>441_bases
ATGCCCGAGACCGAAACTCTTCCGACCGAGGCGACGGTCGCCCCGGATGTCCCGCTCAGACCGGCGATTCACCTCGATCA
CTGCGTGATCCACGTCAGCGACTGGGCGCGCTCCAACACCTTCTACCGGGACGTGGTGGGTGCCGAGATCGTCGAGCGCG
GCGCCGGCTTCGCCTACCGGTTCGGCGGCGTCCAGCTCAATTGCCACGGCCCGGGCGTCGAGGCCGTGCCGGTGGCGGCG
ACTCCCGTCCAGCCGGGCAACAGCGACCTGTGCTTCCGCTGGTCGGGCGCGATCGAGACCGCGATCGCGCATCTCGAGGC
CGCCGGGGTCCCGGTGGAACTCGGCCCGGTGGAGCGGCACGGCGCCGCGGGTGCGGGGATCAGCGTCTACTTCCGGGATC
CGGACGGCTCGCTCCTGGAGTTCATCACCTACGCGGGATGA

Upstream 100 bases:

>100_bases
CCGCCGCAGCCGGCCGCGCGCGGGCCGCTCCCGCGGCCACGGTTGCGCCCTAATTCTGAATCGCAGAGGCGCTCTATTGC
GCCCGGCGCGGAGGTGAGCG

Downstream 100 bases:

>100_bases
TCAGCCCCGGCTCTCGGCCAGCGCCTGATTGGTCTGCTCCAGCCGCAGCGCCAGCACGCGCATCAGGGCGATGCTGATCT
GCGGAAACTGTGCCAGGAGT

Product: glyoxalase/bleomycin resistance protein/dioxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MPETETLPTEATVAPDVPLRPAIHLDHCVIHVSDWARSNTFYRDVVGAEIVERGAGFAYRFGGVQLNCHGPGVEAVPVAA
TPVQPGNSDLCFRWSGAIETAIAHLEAAGVPVELGPVERHGAAGAGISVYFRDPDGSLLEFITYAG

Sequences:

>Translated_146_residues
MPETETLPTEATVAPDVPLRPAIHLDHCVIHVSDWARSNTFYRDVVGAEIVERGAGFAYRFGGVQLNCHGPGVEAVPVAA
TPVQPGNSDLCFRWSGAIETAIAHLEAAGVPVELGPVERHGAAGAGISVYFRDPDGSLLEFITYAG
>Mature_145_residues
PETETLPTEATVAPDVPLRPAIHLDHCVIHVSDWARSNTFYRDVVGAEIVERGAGFAYRFGGVQLNCHGPGVEAVPVAAT
PVQPGNSDLCFRWSGAIETAIAHLEAAGVPVELGPVERHGAAGAGISVYFRDPDGSLLEFITYAG

Specific function: Is critically involved in promoting the replication of S.typhimurium cells inside host macrophages, suggesting a role in the establishment of bacterial colonization within macrophages. May be involved in the biosynthesis and modification of the peptidogly

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI254039722, Length=122, Percent_Identity=40.9836065573771, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 15420; Mature: 15289

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPETETLPTEATVAPDVPLRPAIHLDHCVIHVSDWARSNTFYRDVVGAEIVERGAGFAYR
CCCCCCCCCCCEECCCCCCCCCEEECEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEE
FGGVQLNCHGPGVEAVPVAATPVQPGNSDLCFRWSGAIETAIAHLEAAGVPVELGPVERH
ECCEEEEECCCCCCEEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHCCCCEEECCCCCC
GAAGAGISVYFRDPDGSLLEFITYAG
CCCCCCEEEEEECCCCCHHHHEECCC
>Mature Secondary Structure 
PETETLPTEATVAPDVPLRPAIHLDHCVIHVSDWARSNTFYRDVVGAEIVERGAGFAYR
CCCCCCCCCCEECCCCCCCCCEEECEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEE
FGGVQLNCHGPGVEAVPVAATPVQPGNSDLCFRWSGAIETAIAHLEAAGVPVELGPVERH
ECCEEEEECCCCCCEEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHCCCCEEECCCCCC
GAAGAGISVYFRDPDGSLLEFITYAG
CCCCCCEEEEEECCCCCHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]