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The map label for this gene is yehW [H]

Identifier: 170751270

GI number: 170751270

Start: 5216813

End: 5217556

Strand: Reverse

Name: yehW [H]

Synonym: Mrad2831_4887

Alternate gene names: 170751270

Gene position: 5217556-5216813 (Counterclockwise)

Preceding gene: 170751271

Following gene: 170751269

Centisome position: 85.85

GC content: 74.87

Gene sequence:

>744_bases
GTGATCGGCGCCCCGCGGATCGCCCGGGCCGCGCTCCTCGCCCTGCTGGGGGCGTTCCTGGTCGCTCCGGGCCTGTTCGC
GCCCCTGTTCCGGCCCTTCGCCCCCGGCGACGCGCCGCCGATCTACGCCCAGACGCCGCTGCTGACGCTCGCCGTCACCC
ACCTCCTGCTCGTCGCGGCCGCGACCACGATCGCGGCCGCGATCGCCCTCGGCCTCGCGGTCGCGGCCACGCGGCCGGCC
GGCCGCGACGTGCTGCCGTTCGCCCGGTCGGTGGCCCGCATCGGGCAGACCTTCCCGCCCGTCGCGGTCCTGGCCCTGGC
CGTCCCGATCCTCGGGTTCGGGGCGGTTCCGACCCTGATCGCCCTGGTCCTCTACGGGCTCCTGCCGATCTTCGAGACCG
CGCTCACCGGGCTCGAGGATCTCGACCCGGCGCTGATGGAGGCCGCGCGCGGCATGGGGCTGACCGACCGGCAGCGGCTC
GTCCGCGTCGAGCTGCCCCTGGCGCTGCCGATGATCCTGTCGGGGATCCGCCTCGCCGCCGTCATCGGGCTGGCGACGGC
GACGATCGGCTCGACGGTCGCGGCCAGCACCCTCGGCGAGGTGATCATCTCCGGCCTGCTCACCGGCAACACCGCCTACG
TGCTGCAGGGCGGCCTCGCCGTGTCCGCGCTGGCCCTGCTGATCGATGGCGGCTTCCGAAGCCTCGAGCGCGAAGCGGCA
CGACGGGCTGGATTTCGTTCCTAG

Upstream 100 bases:

>100_bases
AGAGCCTGTGGTCGCGGCGCCCGGCCCTGCCGGTCAGCCGCGACGGCGTCGTCCTGGGCCGGGTGACGCGGGAGGCCCTC
GCGGCGCGGGGTGCCCGGCC

Downstream 100 bases:

>100_bases
ACGCGACTAGAACGCCAGCGGGGCCGTACGCGCGGCCCTGGGGCGTGGAACCCCCTGTCTGATGGTCGGTGCCGACCACA
ACGGCACCCGTATCCTTGAC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MIGAPRIARAALLALLGAFLVAPGLFAPLFRPFAPGDAPPIYAQTPLLTLAVTHLLLVAAATTIAAAIALGLAVAATRPA
GRDVLPFARSVARIGQTFPPVAVLALAVPILGFGAVPTLIALVLYGLLPIFETALTGLEDLDPALMEAARGMGLTDRQRL
VRVELPLALPMILSGIRLAAVIGLATATIGSTVAASTLGEVIISGLLTGNTAYVLQGGLAVSALALLIDGGFRSLEREAA
RRAGFRS

Sequences:

>Translated_247_residues
MIGAPRIARAALLALLGAFLVAPGLFAPLFRPFAPGDAPPIYAQTPLLTLAVTHLLLVAAATTIAAAIALGLAVAATRPA
GRDVLPFARSVARIGQTFPPVAVLALAVPILGFGAVPTLIALVLYGLLPIFETALTGLEDLDPALMEAARGMGLTDRQRL
VRVELPLALPMILSGIRLAAVIGLATATIGSTVAASTLGEVIISGLLTGNTAYVLQGGLAVSALALLIDGGFRSLEREAA
RRAGFRS
>Mature_247_residues
MIGAPRIARAALLALLGAFLVAPGLFAPLFRPFAPGDAPPIYAQTPLLTLAVTHLLLVAAATTIAAAIALGLAVAATRPA
GRDVLPFARSVARIGQTFPPVAVLALAVPILGFGAVPTLIALVLYGLLPIFETALTGLEDLDPALMEAARGMGLTDRQRL
VRVELPLALPMILSGIRLAAVIGLATATIGSTVAASTLGEVIISGLLTGNTAYVLQGGLAVSALALLIDGGFRSLEREAA
RRAGFRS

Specific function: May be part of an ABC transporter complex involved in uptake of osmoprotectant molecules. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=216, Percent_Identity=46.7592592592593, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1788451, Length=156, Percent_Identity=37.8205128205128, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1789033, Length=184, Percent_Identity=27.1739130434783, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25149; Mature: 25149

Theoretical pI: Translated: 10.90; Mature: 10.90

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGAPRIARAALLALLGAFLVAPGLFAPLFRPFAPGDAPPIYAQTPLLTLAVTHLLLVAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
ATTIAAAIALGLAVAATRPAGRDVLPFARSVARIGQTFPPVAVLALAVPILGFGAVPTLI
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHH
ALVLYGLLPIFETALTGLEDLDPALMEAARGMGLTDRQRLVRVELPLALPMILSGIRLAA
HHHHHHHHHHHHHHHHCHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VIGLATATIGSTVAASTLGEVIISGLLTGNTAYVLQGGLAVSALALLIDGGFRSLEREAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
RRAGFRS
HHCCCCC
>Mature Secondary Structure
MIGAPRIARAALLALLGAFLVAPGLFAPLFRPFAPGDAPPIYAQTPLLTLAVTHLLLVAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
ATTIAAAIALGLAVAATRPAGRDVLPFARSVARIGQTFPPVAVLALAVPILGFGAVPTLI
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHH
ALVLYGLLPIFETALTGLEDLDPALMEAARGMGLTDRQRLVRVELPLALPMILSGIRLAA
HHHHHHHHHHHHHHHHCHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VIGLATATIGSTVAASTLGEVIISGLLTGNTAYVLQGGLAVSALALLIDGGFRSLEREAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
RRAGFRS
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]