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The map label for this gene is feaR [H]

Identifier: 170751234

GI number: 170751234

Start: 5180653

End: 5181621

Strand: Reverse

Name: feaR [H]

Synonym: Mrad2831_4851

Alternate gene names: 170751234

Gene position: 5181621-5180653 (Counterclockwise)

Preceding gene: 170751236

Following gene: 170751231

Centisome position: 85.25

GC content: 68.21

Gene sequence:

>969_bases
ATGAGGACTTTGTTCTCGACGGCGGATTTCAAGCCGAAAGACAGTTTCCGCCTCTGGCGTGAAACGATCTTCGAGCGCAT
CGTGCCGGTCGAGCTGACCCCTGCGACGGCACACGCCTTCGCCGGCACCCTGGAGGCCGCCGAGGTCGGACCGCTGCTGA
TCACGCGCGTGACGCAGAGCGCCGTCACCACCGTCGCGACCCCGGACACGATCCGCCGGCACGGCAAGTACGAGACCCTG
AACGTCGCGATCACGCTGAAGGGCCGCGTGTACAGCGCGCAGGACGACCGCACCGCCATCCAGAATCCCGGCGACATCGT
CGTGATGGACCGGCGGCCGGCCACGATGGCCTCCGACGTCGACACGCAGACGCTGTTCGTCGAGCTGCCGCGCGAGTCGC
TGGAGCGCGCCCTCGGCTCGACGCGCCGCTTCACGTCCCTCACGATCGGCGCGGATCAGGTCGGCACGTCGATGGTCACG
ACCTTCTTCCAGGAACTGGTCCGCAATGCCGGGCGGCTGACGCCCGACATGTCGAACCGCATGGCGTCGGTCGGCGTCGA
TCTCATCGTCGCGAGCATCGCGGAGCGCCTCGCGCACGACACCCCCAAGAACATCCAGGGCGTCCTGATCTTCCAGCGCG
CCCTGGCACATATCGAGGCCCATCTCGGCGACCTGAACCTCGACCCCGCCCGGCTCGCGGCGGCCGTGGGCGTGTCGCTG
CGCCACCTCCAGGCCCTGTTCCGCGAGCAGGACCGGAACATCGCCGACTGGATCTGGCGGCGGCGCCTGGAGATCGCCGC
GCAGCGTCTGGCCGATCCCGGCTTCGCCCATCTCGCCGTCGGGGAACTGGCCTATAGCTGCGGCTTCTGCACCCAGAGCC
ATTTCAGCCGACGTTTCAAGGACAGCTACGGGATCTCACCGAGCGAGTACCGGTGGCGCAACCGGAGCGCGCCCGAACTC
GTCGGCTGA

Upstream 100 bases:

>100_bases
CAAGAACCTTCATAAGTTGGCCCGCGCCGTTGCGCTTGCCTGAGAGCGTGCTACCGTTTTCCCGAGCGCGCGCGGCGAAG
CATGAATACAAGAAGTTGCG

Downstream 100 bases:

>100_bases
CGATCCGCTACTGCAGGACGGCGCCCGCCGTGTTCGCGCGGATCCATCCCGGAGCGAGGATGTCGCCGCCCTCGGTGATG
ATCCAGGGATTGGCATCCTC

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MRTLFSTADFKPKDSFRLWRETIFERIVPVELTPATAHAFAGTLEAAEVGPLLITRVTQSAVTTVATPDTIRRHGKYETL
NVAITLKGRVYSAQDDRTAIQNPGDIVVMDRRPATMASDVDTQTLFVELPRESLERALGSTRRFTSLTIGADQVGTSMVT
TFFQELVRNAGRLTPDMSNRMASVGVDLIVASIAERLAHDTPKNIQGVLIFQRALAHIEAHLGDLNLDPARLAAAVGVSL
RHLQALFREQDRNIADWIWRRRLEIAAQRLADPGFAHLAVGELAYSCGFCTQSHFSRRFKDSYGISPSEYRWRNRSAPEL
VG

Sequences:

>Translated_322_residues
MRTLFSTADFKPKDSFRLWRETIFERIVPVELTPATAHAFAGTLEAAEVGPLLITRVTQSAVTTVATPDTIRRHGKYETL
NVAITLKGRVYSAQDDRTAIQNPGDIVVMDRRPATMASDVDTQTLFVELPRESLERALGSTRRFTSLTIGADQVGTSMVT
TFFQELVRNAGRLTPDMSNRMASVGVDLIVASIAERLAHDTPKNIQGVLIFQRALAHIEAHLGDLNLDPARLAAAVGVSL
RHLQALFREQDRNIADWIWRRRLEIAAQRLADPGFAHLAVGELAYSCGFCTQSHFSRRFKDSYGISPSEYRWRNRSAPEL
VG
>Mature_322_residues
MRTLFSTADFKPKDSFRLWRETIFERIVPVELTPATAHAFAGTLEAAEVGPLLITRVTQSAVTTVATPDTIRRHGKYETL
NVAITLKGRVYSAQDDRTAIQNPGDIVVMDRRPATMASDVDTQTLFVELPRESLERALGSTRRFTSLTIGADQVGTSMVT
TFFQELVRNAGRLTPDMSNRMASVGVDLIVASIAERLAHDTPKNIQGVLIFQRALAHIEAHLGDLNLDPARLAAAVGVSL
RHLQALFREQDRNIADWIWRRRLEIAAQRLADPGFAHLAVGELAYSCGFCTQSHFSRRFKDSYGISPSEYRWRNRSAPEL
VG

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=277, Percent_Identity=24.187725631769, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 35832; Mature: 35832

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLFSTADFKPKDSFRLWRETIFERIVPVELTPATAHAFAGTLEAAEVGPLLITRVTQS
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHCHHHHHHHHHH
AVTTVATPDTIRRHGKYETLNVAITLKGRVYSAQDDRTAIQNPGDIVVMDRRPATMASDV
HHHHCCCCHHHHHCCCCEEEEEEEEEECEEEECCCCCHHHCCCCCEEEECCCCCCHHCCC
DTQTLFVELPRESLERALGSTRRFTSLTIGADQVGTSMVTTFFQELVRNAGRLTPDMSNR
CCEEEEEECCHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
MASVGVDLIVASIAERLAHDTPKNIQGVLIFQRALAHIEAHLGDLNLDPARLAAAVGVSL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
RHLQALFREQDRNIADWIWRRRLEIAAQRLADPGFAHLAVGELAYSCGFCTQSHFSRRFK
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
DSYGISPSEYRWRNRSAPELVG
HHCCCCCHHHCCCCCCCCCCCC
>Mature Secondary Structure
MRTLFSTADFKPKDSFRLWRETIFERIVPVELTPATAHAFAGTLEAAEVGPLLITRVTQS
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHCHHHHHHHHHH
AVTTVATPDTIRRHGKYETLNVAITLKGRVYSAQDDRTAIQNPGDIVVMDRRPATMASDV
HHHHCCCCHHHHHCCCCEEEEEEEEEECEEEECCCCCHHHCCCCCEEEECCCCCCHHCCC
DTQTLFVELPRESLERALGSTRRFTSLTIGADQVGTSMVTTFFQELVRNAGRLTPDMSNR
CCEEEEEECCHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
MASVGVDLIVASIAERLAHDTPKNIQGVLIFQRALAHIEAHLGDLNLDPARLAAAVGVSL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
RHLQALFREQDRNIADWIWRRRLEIAAQRLADPGFAHLAVGELAYSCGFCTQSHFSRRFK
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
DSYGISPSEYRWRNRSAPELVG
HHCCCCCHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]