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The map label for this gene is pncB [H]

Identifier: 170748560

GI number: 170748560

Start: 2284375

End: 2285667

Strand: Reverse

Name: pncB [H]

Synonym: Mrad2831_2142

Alternate gene names: 170748560

Gene position: 2285667-2284375 (Counterclockwise)

Preceding gene: 170748561

Following gene: 170748559

Centisome position: 37.61

GC content: 69.06

Gene sequence:

>1293_bases
ATGCTGGATCTGGCGAAGCGAGTCTACGACCACAGCTTCCGCATCGACCCGATCGTGCGGTCGCTGCTCGACACGGATTT
CTACAAGCTCCTGATGGCGCAGACGATCCTGCGCCGACACCCCGACATCCGGACCACCTTCGGCATCACCAACCGCACGC
GGCGCATCCGCATCGCCGACGAGGTCGATGCCGGTCTGCTGCGCGAGCAGCTCGACCACGCCCGGACCCTGCGCCTCAGC
AAGGGCGAGATCACGTGGCTGCGCGGCAACGTCTTCCGCGGCCAGGGACGAATCCTGGGACCCGAATTCGTGAGCTGGTT
CGAGGCCTTCCAACTCCCCGAATACGAGCTCGCCGTCCATGACGGCCAGTACGAGCTGACCTTCCACGGTCCCTGGGTCG
AGACCACGATGTGGGAGGTCCCGGCGCTCGCGATCCTCAACGAGTTGCGGGCGCGGGCCGTGCTGCGTGGCCTCGGCAAG
CTCGACCTGCAGGTGCTCTACGCCCGCGCCATGACCCGGGTCTGGGAGAAGATCGAGCGCCTGCAGAGGCTGCCGGACCT
GTCGGTGGCGGATTTCGGCACGCGCCGGCGCCACGGCTTCCTGTGGCAGGACTGGTGCGTGCAGGCGATGGCGGAGGGTC
TCGGCGGCGCGTTCCTCGGCACCTCCAACTGCCTGATCGCGGCCCGGCAGGAGGTCGAGCCGGTCGGCACGAACGCTCAC
GAACTGCCGATGGTCTACGCGGCGCTCGCCGAGGACGACGCGGCGCTCGCCGCCGCGCCCTACGCGGTGCTGTCGGACTG
GCAGGAGGATTACGGCGGCAACCTGCTGGTGATCCTGCCCGACACCTACGGCACCACCGGATTCCTGGCGAACGCCCCGG
ACTGGGTGAGCGACTGGACCGGCATCCGCATCGACTCGAAGGACCCGATCGAGGGCGGCGAGGAGGCGATCCGCTTCTGG
CAGGCTCGCGGGCACGACCCGCGGGACAAGCTCGCGATCTTCTCCGACGGGCTCGACATCGACGAGATCGAGCGCATCCA
CGCCCGGTTCCACGGCCGCATGCGCATCGGCTACGGGTGGGGCACGCTGCTCACCAACGATTTCCGCGGGCTCCTGCCGG
AGGGGAAGCTCGACCCGGTCTCGATCGTCTGCAAGGTCACCGAGGCCGACGGCCGGCCGACCGTGAAGCTCTCCGACAAT
CCCACCAAGGCGCAGGGGCCGGCCGACGAGGTCGCCCGCTACCGGCGGGTCTTCGCCGTGGGCGAGCAGGAGGCGCTGCC
GGTACTGGTGTGA

Upstream 100 bases:

>100_bases
TTTCCGCGGGCGGTCTCCGGGAGGAGGCCGCCCGTCTTCTTGACGTCGGCGGTTCCGGCATGCGCTCTGCGCGATCGAAG
CGCGGCAGAGTGCCTTACGA

Downstream 100 bases:

>100_bases
CGGGCGCACACCACCGGCGGAGGACCCCGGCACCGCCGGCCTCGCGAGCGGAGCGACGTGATGACGGTGAGGGACCCGTC
CACCGAAGCGCTCGAGCGGA

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MLDLAKRVYDHSFRIDPIVRSLLDTDFYKLLMAQTILRRHPDIRTTFGITNRTRRIRIADEVDAGLLREQLDHARTLRLS
KGEITWLRGNVFRGQGRILGPEFVSWFEAFQLPEYELAVHDGQYELTFHGPWVETTMWEVPALAILNELRARAVLRGLGK
LDLQVLYARAMTRVWEKIERLQRLPDLSVADFGTRRRHGFLWQDWCVQAMAEGLGGAFLGTSNCLIAARQEVEPVGTNAH
ELPMVYAALAEDDAALAAAPYAVLSDWQEDYGGNLLVILPDTYGTTGFLANAPDWVSDWTGIRIDSKDPIEGGEEAIRFW
QARGHDPRDKLAIFSDGLDIDEIERIHARFHGRMRIGYGWGTLLTNDFRGLLPEGKLDPVSIVCKVTEADGRPTVKLSDN
PTKAQGPADEVARYRRVFAVGEQEALPVLV

Sequences:

>Translated_430_residues
MLDLAKRVYDHSFRIDPIVRSLLDTDFYKLLMAQTILRRHPDIRTTFGITNRTRRIRIADEVDAGLLREQLDHARTLRLS
KGEITWLRGNVFRGQGRILGPEFVSWFEAFQLPEYELAVHDGQYELTFHGPWVETTMWEVPALAILNELRARAVLRGLGK
LDLQVLYARAMTRVWEKIERLQRLPDLSVADFGTRRRHGFLWQDWCVQAMAEGLGGAFLGTSNCLIAARQEVEPVGTNAH
ELPMVYAALAEDDAALAAAPYAVLSDWQEDYGGNLLVILPDTYGTTGFLANAPDWVSDWTGIRIDSKDPIEGGEEAIRFW
QARGHDPRDKLAIFSDGLDIDEIERIHARFHGRMRIGYGWGTLLTNDFRGLLPEGKLDPVSIVCKVTEADGRPTVKLSDN
PTKAQGPADEVARYRRVFAVGEQEALPVLV
>Mature_430_residues
MLDLAKRVYDHSFRIDPIVRSLLDTDFYKLLMAQTILRRHPDIRTTFGITNRTRRIRIADEVDAGLLREQLDHARTLRLS
KGEITWLRGNVFRGQGRILGPEFVSWFEAFQLPEYELAVHDGQYELTFHGPWVETTMWEVPALAILNELRARAVLRGLGK
LDLQVLYARAMTRVWEKIERLQRLPDLSVADFGTRRRHGFLWQDWCVQAMAEGLGGAFLGTSNCLIAARQEVEPVGTNAH
ELPMVYAALAEDDAALAAAPYAVLSDWQEDYGGNLLVILPDTYGTTGFLANAPDWVSDWTGIRIDSKDPIEGGEEAIRFW
QARGHDPRDKLAIFSDGLDIDEIERIHARFHGRMRIGYGWGTLLTNDFRGLLPEGKLDPVSIVCKVTEADGRPTVKLSDN
PTKAQGPADEVARYRRVFAVGEQEALPVLV

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=396, Percent_Identity=31.5656565656566, Blast_Score=184, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6324783, Length=432, Percent_Identity=29.1666666666667, Blast_Score=171, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 48588; Mature: 48588

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLAKRVYDHSFRIDPIVRSLLDTDFYKLLMAQTILRRHPDIRTTFGITNRTRRIRIAD
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEHH
EVDAGLLREQLDHARTLRLSKGEITWLRGNVFRGQGRILGPEFVSWFEAFQLPEYELAVH
HHHHHHHHHHHHHHHEEEECCCCEEEEECCEEECCCCEECHHHHHHHHHHCCCCEEEEEE
DGQYELTFHGPWVETTMWEVPALAILNELRARAVLRGLGKLDLQVLYARAMTRVWEKIER
CCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LQRLPDLSVADFGTRRRHGFLWQDWCVQAMAEGLGGAFLGTSNCLIAARQEVEPVGTNAH
HHHCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCCCH
ELPMVYAALAEDDAALAAAPYAVLSDWQEDYGGNLLVILPDTYGTTGFLANAPDWVSDWT
HHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHCCCC
GIRIDSKDPIEGGEEAIRFWQARGHDPRDKLAIFSDGLDIDEIERIHARFHGRMRIGYGW
CEEECCCCCCCCHHHHHHHHHHCCCCCHHCEEEEECCCCHHHHHHHHHHHCCCEEEEECH
GTLLTNDFRGLLPEGKLDPVSIVCKVTEADGRPTVKLSDNPTKAQGPADEVARYRRVFAV
HHHHHCCHHCCCCCCCCCCEEEEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHC
GEQEALPVLV
CCCCCCCCCC
>Mature Secondary Structure
MLDLAKRVYDHSFRIDPIVRSLLDTDFYKLLMAQTILRRHPDIRTTFGITNRTRRIRIAD
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEHH
EVDAGLLREQLDHARTLRLSKGEITWLRGNVFRGQGRILGPEFVSWFEAFQLPEYELAVH
HHHHHHHHHHHHHHHEEEECCCCEEEEECCEEECCCCEECHHHHHHHHHHCCCCEEEEEE
DGQYELTFHGPWVETTMWEVPALAILNELRARAVLRGLGKLDLQVLYARAMTRVWEKIER
CCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LQRLPDLSVADFGTRRRHGFLWQDWCVQAMAEGLGGAFLGTSNCLIAARQEVEPVGTNAH
HHHCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCCCH
ELPMVYAALAEDDAALAAAPYAVLSDWQEDYGGNLLVILPDTYGTTGFLANAPDWVSDWT
HHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCHHHCCCC
GIRIDSKDPIEGGEEAIRFWQARGHDPRDKLAIFSDGLDIDEIERIHARFHGRMRIGYGW
CEEECCCCCCCCHHHHHHHHHHCCCCCHHCEEEEECCCCHHHHHHHHHHHCCCEEEEECH
GTLLTNDFRGLLPEGKLDPVSIVCKVTEADGRPTVKLSDNPTKAQGPADEVARYRRVFAV
HHHHHCCHHCCCCCCCCCCEEEEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHC
GEQEALPVLV
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA