BacMap

Definition	Methylobacterium radiotolerans JCM 2831 chromosome, complete genome.
Accession	NC_010505
Length	6,077,833

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The map label for this gene is yusZ [H]

Identifier: 170748527

GI number: 170748527

Start: 2243487

End: 2244233

Strand: Reverse

Name: yusZ [H]

Synonym: Mrad2831_2109

Alternate gene names: 170748527

Gene position: 2244233-2243487 (Counterclockwise)

Preceding gene: 170748530

Following gene: 170748522

Centisome position: 36.92

GC content: 73.49

Gene sequence:

>747_bases
ATGAACACGATCCTGATCACCGGTTGCTCGTCCGGCTTCGGCCTGGAGACGGCCCGCACCTTCCTCGCGCGTGGCTGGCG
CGTGGTCGCCACGATGCGCAGGCCGCGGGGCGATCTGCTGCCGCCGTCCGATCGTCTCAGCCTCCTGCCGCTGGACGTGA
CCGACCGAGACAGCGTCGCCCGCGCGGTCGCGGCCGCCGGACCGATCGACGTGCTGGTCAACAACGCGGGCGTCGGGCTC
CTGAACGCGCTGGAGGGCGTCTCGATGGACGCCGCGCGGGAGGTGTTCGAGACGAACACCCTCGGCACGATCGCGATGAC
CCGGGCCGTACTGCCGCAGTTCCGGGAGCGCCGTGCGGGCGTCGTCGTCAACGTGACGTCGAGCGTGACGCAGCGCCCGC
TGCATCTGCTGTCGGTCTACACGGCGAGCAAGGCGGCGGTGAACGCCTTCACCGAGTCCCTGGCGCTGGAACTCGAACCG
TTCGGCGTGCGCGCGCGGCTGGTCATCCCCGGCCGCGCCCCGGAGACCGCGTTCGGCGCCAACGCGCGCGCCCGCATGGG
CATGGACATCCCCGAGGCCTACGCGGCGGTGGCCGCGCAGGTCTTCGCCGGCTTCCAGCAGGCGGACGAGGACCTGACCC
GGCCCGCGGATGTGGCGGAGGCGGTGTGGCGCGCGGCGACGGACCCGTCATGCCCCACGCGCCTGCCGGCCGGTGCCGAC
GCGGTGGCGTGGGCCAGGGCGGGCTGA

Upstream 100 bases:

>100_bases
GCATTCTCGGACGCTCGCCAATGCGAACCGGACTTGCGCACGTATCGGGTCCGGCCCGCGCTCCCTATCACCCCGTTGCC
CCATCTGCACGGGAGTTCCC

Downstream 100 bases:

>100_bases
GGGTGGGCTGAGGACGGAGTGCGCGCGGAGTGAGGCCGGCGGCGAACCGCGTCGGCCCCGGACCGGAGGTCCGGGATCCC
GACGCGGAAGCCCGGGCTCA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: ORFA [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MNTILITGCSSGFGLETARTFLARGWRVVATMRRPRGDLLPPSDRLSLLPLDVTDRDSVARAVAAAGPIDVLVNNAGVGL
LNALEGVSMDAAREVFETNTLGTIAMTRAVLPQFRERRAGVVVNVTSSVTQRPLHLLSVYTASKAAVNAFTESLALELEP
FGVRARLVIPGRAPETAFGANARARMGMDIPEAYAAVAAQVFAGFQQADEDLTRPADVAEAVWRAATDPSCPTRLPAGAD
AVAWARAG

Sequences:

>Translated_248_residues
MNTILITGCSSGFGLETARTFLARGWRVVATMRRPRGDLLPPSDRLSLLPLDVTDRDSVARAVAAAGPIDVLVNNAGVGL
LNALEGVSMDAAREVFETNTLGTIAMTRAVLPQFRERRAGVVVNVTSSVTQRPLHLLSVYTASKAAVNAFTESLALELEP
FGVRARLVIPGRAPETAFGANARARMGMDIPEAYAAVAAQVFAGFQQADEDLTRPADVAEAVWRAATDPSCPTRLPAGAD
AVAWARAG
>Mature_248_residues
MNTILITGCSSGFGLETARTFLARGWRVVATMRRPRGDLLPPSDRLSLLPLDVTDRDSVARAVAAAGPIDVLVNNAGVGL
LNALEGVSMDAAREVFETNTLGTIAMTRAVLPQFRERRAGVVVNVTSSVTQRPLHLLSVYTASKAAVNAFTESLALELEP
FGVRARLVIPGRAPETAFGANARARMGMDIPEAYAAVAAQVFAGFQQADEDLTRPADVAEAVWRAATDPSCPTRLPAGAD
AVAWARAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=257, Percent_Identity=34.2412451361868, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI223718074, Length=192, Percent_Identity=40.1041666666667, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI20149619, Length=186, Percent_Identity=31.1827956989247, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI150247226, Length=260, Percent_Identity=33.0769230769231, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI40548397, Length=179, Percent_Identity=37.9888268156425, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI214010158, Length=179, Percent_Identity=37.9888268156425, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI214010156, Length=179, Percent_Identity=37.9888268156425, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI22758144, Length=179, Percent_Identity=37.9888268156425, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI7705925, Length=171, Percent_Identity=34.5029239766082, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI19743808, Length=178, Percent_Identity=36.5168539325843, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI44680136, Length=215, Percent_Identity=31.1627906976744, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI44680133, Length=215, Percent_Identity=31.1627906976744, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI17738292, Length=215, Percent_Identity=31.1627906976744, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI7706318, Length=185, Percent_Identity=33.5135135135135, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI119392083, Length=184, Percent_Identity=34.7826086956522, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI50726952, Length=263, Percent_Identity=34.2205323193916, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI22507405, Length=194, Percent_Identity=34.5360824742268, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI4503817, Length=197, Percent_Identity=26.3959390862944, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI10190704, Length=180, Percent_Identity=31.1111111111111, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI19923817, Length=183, Percent_Identity=30.0546448087432, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI157739938, Length=184, Percent_Identity=26.6304347826087, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI32483357, Length=182, Percent_Identity=32.4175824175824, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI4504503, Length=183, Percent_Identity=29.5081967213115, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI33667109, Length=198, Percent_Identity=31.3131313131313, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI59889578, Length=163, Percent_Identity=33.7423312883436, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI5031737, Length=178, Percent_Identity=31.4606741573034, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787820, Length=237, Percent_Identity=34.1772151898734, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1786812, Length=174, Percent_Identity=31.0344827586207, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082100, Length=182, Percent_Identity=34.0659340659341, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786701, Length=180, Percent_Identity=31.6666666666667, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787335, Length=176, Percent_Identity=31.25, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790717, Length=180, Percent_Identity=27.2222222222222, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788459, Length=197, Percent_Identity=27.4111675126904, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=247, Percent_Identity=30.3643724696356, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=233, Percent_Identity=31.3304721030043, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=176, Percent_Identity=32.9545454545455, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=229, Percent_Identity=31.8777292576419, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17557780, Length=188, Percent_Identity=32.9787234042553, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=246, Percent_Identity=30.8943089430894, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=218, Percent_Identity=29.3577981651376, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=31.6, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI72001658, Length=208, Percent_Identity=26.9230769230769, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=32.7935222672065, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=206, Percent_Identity=28.6407766990291, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=185, Percent_Identity=29.1891891891892, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=243, Percent_Identity=27.5720164609054, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=192, Percent_Identity=29.1666666666667, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=204, Percent_Identity=27.9411764705882, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=192, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322067, Length=177, Percent_Identity=29.9435028248588, Blast_Score=69, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21358495, Length=184, Percent_Identity=30.9782608695652, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI23397609, Length=175, Percent_Identity=38.2857142857143, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI28571526, Length=229, Percent_Identity=32.3144104803493, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357041, Length=229, Percent_Identity=31.4410480349345, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24644339, Length=228, Percent_Identity=31.5789473684211, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24643142, Length=170, Percent_Identity=31.1764705882353, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24651139, Length=231, Percent_Identity=26.4069264069264, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356301, Length=199, Percent_Identity=26.1306532663317, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI116007238, Length=187, Percent_Identity=31.0160427807487, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI116007236, Length=190, Percent_Identity=31.5789473684211, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24584748, Length=213, Percent_Identity=27.2300469483568, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584744, Length=213, Percent_Identity=27.2300469483568, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161076933, Length=213, Percent_Identity=27.2300469483568, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28574402, Length=213, Percent_Identity=27.2300469483568, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26183; Mature: 26183

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTILITGCSSGFGLETARTFLARGWRVVATMRRPRGDLLPPSDRLSLLPLDVTDRDSVA
CCEEEEEECCCCCCHHHHHHHHHCCCEEEEEHHCCCCCCCCCCCCCEEEECCCCCHHHHH
RAVAAAGPIDVLVNNAGVGLLNALEGVSMDAAREVFETNTLGTIAMTRAVLPQFRERRAG
HHHHHCCCCEEEECCCCCHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
VVVNVTSSVTQRPLHLLSVYTASKAAVNAFTESLALELEPFGVRARLVIPGRAPETAFGA
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEECCCCCCCCCCC
NARARMGMDIPEAYAAVAAQVFAGFQQADEDLTRPADVAEAVWRAATDPSCPTRLPAGAD
CCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCC
AVAWARAG
HHHHCCCC
>Mature Secondary Structure
MNTILITGCSSGFGLETARTFLARGWRVVATMRRPRGDLLPPSDRLSLLPLDVTDRDSVA
CCEEEEEECCCCCCHHHHHHHHHCCCEEEEEHHCCCCCCCCCCCCCEEEECCCCCHHHHH
RAVAAAGPIDVLVNNAGVGLLNALEGVSMDAAREVFETNTLGTIAMTRAVLPQFRERRAG
HHHHHCCCCEEEECCCCCHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
VVVNVTSSVTQRPLHLLSVYTASKAAVNAFTESLALELEPFGVRARLVIPGRAPETAFGA
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEECCCCCCCCCCC
NARARMGMDIPEAYAAVAAQVFAGFQQADEDLTRPADVAEAVWRAATDPSCPTRLPAGAD
CCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCC
AVAWARAG
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377; 8396117 [H]