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The map label for this gene is mntH [H]

Identifier: 170748451

GI number: 170748451

Start: 2160378

End: 2161679

Strand: Reverse

Name: mntH [H]

Synonym: Mrad2831_2033

Alternate gene names: 170748451

Gene position: 2161679-2160378 (Counterclockwise)

Preceding gene: 170748452

Following gene: 170748449

Centisome position: 35.57

GC content: 70.43

Gene sequence:

>1302_bases
ATGGACCAGCCCCGTCCGAAACCCGACACCGACGACCCGGACAGGCCACGCGGCCGTGGCAGCCTCCTCCACGCCCTCGG
TACCGGGGTGATCACCGGCGCCGCCGACGACGACCCCTCCGCCATCGGCACCTATGCGAGCGCCGGCGCCCGGTACGGCC
TCGGGTTCCTGTGGATCGCCCCGGTCGTCCTGCCGATGATGGTCGTGGTCGTCTACCTCTCTGCCAAGCTCGGGCAGGTC
TACGGCAAGGGCCTGTTCGCCATCGTGCGCGACCGCTACCCGCGCTGGGTCCTCTACCCGCTCGTGGCCGGCGCCTTCGG
GGGCAACGTCATCGAGGCGGCGGCCAATCTCGGCGGGATCGGCGCGGCCCTCAACCTGCTGGTCCCGGTCCCGATCCCCG
CCATCGTGGTCGGCGCCGCCGCGGCGATCCTGAGCCTGCAGATCTTCGGCTCCTACGCGCTCCTGCGGGACATCTTCCGC
TGGCTGGCGCTCGCCCTGTTCGCCTACGTGGCGGCCGCGATCCTGGCCCGTCCCGACCCCGCCGAGATCCTGCGCGGCAC
CCTCGTGCCGCAGGTCCGGTTCGATGCCGACTTCCTGGCGATGATCGTCGCCTGCATCGGCACCTCGCTCTCGGCCTACA
TCTACACGTGGCAGTCGAACCAGGAGGTCGAGGAGGAGATCGCCCTGGGACGGCGCACGCTGCGGCAGCGCAATGGTGCG
ACCGATGCCGAGCTGCGCAAGACCCGCCGGGACGTGATGATCGGGATGCTGTTCTCGAACATCATCCTCTACTTCATCGT
CCTGTCCACGGGCGCGACGCTGCATCAGGCGGGGCAGACCGAGATCGAGAGCGCCGCCCAGGCCGCGGCCGCCCTGGAGC
CCCTGGCGGGGGCAGGGGCCAAGTACCTGTTCGCCCTCGGGGTCGTCGGCGTCGGCTTCCTGGCGGTGCCGGTGATGACC
ACGGGGGCGGCCTACGACCTCGTGCAGGGGATCGGCCGGACGGGCAGCCTGCACGCCCGTCCGAGCGAGGCCAAGCTGTT
CTACGGCACGATCGCGGCCGTGACCGTGCTGGCGGTGGGTCTGAACTTTCTCGGCTTCAACCCGATGCGGGCGCTCGTCT
GGTCCGGCATCGTGCAGGGCTTCTCGGTGCCGCCGCTCCTGCTCCTCATGATGCTGATGACCAACGACCGGGCCGTGATG
GGCGGCCGCGTCAATGGCCGCGTGACCAACGGGCTCGGATGGCTGACCACCGCGGCGACCTTCCTCGCCACGCTCTGCCT
GGTCGGGACATGGGTCCTGTGA

Upstream 100 bases:

>100_bases
TCGCCTCGGGCGAGCCCCGGAATGACGGCGCGGATGCCTGACCGAGAACACTCGCGAAACCCGACCGGTTGGACCTCGGC
GCACCCTGCGACGAGGATCC

Downstream 100 bases:

>100_bases
GGCGCCGGCCGGGCCGCCTCAGAACGGCGCCGCGAGGCAGCCGTCGAGGGCCGCCTTCAGGGCGGCGGCGTCGGCCTCCG
CGACCGTGAACGTCGCCGTC

Product: natural resistance-associated macrophage protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MDQPRPKPDTDDPDRPRGRGSLLHALGTGVITGAADDDPSAIGTYASAGARYGLGFLWIAPVVLPMMVVVVYLSAKLGQV
YGKGLFAIVRDRYPRWVLYPLVAGAFGGNVIEAAANLGGIGAALNLLVPVPIPAIVVGAAAAILSLQIFGSYALLRDIFR
WLALALFAYVAAAILARPDPAEILRGTLVPQVRFDADFLAMIVACIGTSLSAYIYTWQSNQEVEEEIALGRRTLRQRNGA
TDAELRKTRRDVMIGMLFSNIILYFIVLSTGATLHQAGQTEIESAAQAAAALEPLAGAGAKYLFALGVVGVGFLAVPVMT
TGAAYDLVQGIGRTGSLHARPSEAKLFYGTIAAVTVLAVGLNFLGFNPMRALVWSGIVQGFSVPPLLLLMMLMTNDRAVM
GGRVNGRVTNGLGWLTTAATFLATLCLVGTWVL

Sequences:

>Translated_433_residues
MDQPRPKPDTDDPDRPRGRGSLLHALGTGVITGAADDDPSAIGTYASAGARYGLGFLWIAPVVLPMMVVVVYLSAKLGQV
YGKGLFAIVRDRYPRWVLYPLVAGAFGGNVIEAAANLGGIGAALNLLVPVPIPAIVVGAAAAILSLQIFGSYALLRDIFR
WLALALFAYVAAAILARPDPAEILRGTLVPQVRFDADFLAMIVACIGTSLSAYIYTWQSNQEVEEEIALGRRTLRQRNGA
TDAELRKTRRDVMIGMLFSNIILYFIVLSTGATLHQAGQTEIESAAQAAAALEPLAGAGAKYLFALGVVGVGFLAVPVMT
TGAAYDLVQGIGRTGSLHARPSEAKLFYGTIAAVTVLAVGLNFLGFNPMRALVWSGIVQGFSVPPLLLLMMLMTNDRAVM
GGRVNGRVTNGLGWLTTAATFLATLCLVGTWVL
>Mature_433_residues
MDQPRPKPDTDDPDRPRGRGSLLHALGTGVITGAADDDPSAIGTYASAGARYGLGFLWIAPVVLPMMVVVVYLSAKLGQV
YGKGLFAIVRDRYPRWVLYPLVAGAFGGNVIEAAANLGGIGAALNLLVPVPIPAIVVGAAAAILSLQIFGSYALLRDIFR
WLALALFAYVAAAILARPDPAEILRGTLVPQVRFDADFLAMIVACIGTSLSAYIYTWQSNQEVEEEIALGRRTLRQRNGA
TDAELRKTRRDVMIGMLFSNIILYFIVLSTGATLHQAGQTEIESAAQAAAALEPLAGAGAKYLFALGVVGVGFLAVPVMT
TGAAYDLVQGIGRTGSLHARPSEAKLFYGTIAAVTVLAVGLNFLGFNPMRALVWSGIVQGFSVPPLLLLMMLMTNDRAVM
GGRVNGRVTNGLGWLTTAATFLATLCLVGTWVL

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Escherichia coli, GI1788736, Length=422, Percent_Identity=27.9620853080569, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 45761; Mature: 45761

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQPRPKPDTDDPDRPRGRGSLLHALGTGVITGAADDDPSAIGTYASAGARYGLGFLWIA
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCEEECCCCCCCHHHHHHHHCCHHHCHHHHHHH
PVVLPMMVVVVYLSAKLGQVYGKGLFAIVRDRYPRWVLYPLVAGAFGGNVIEAAANLGGI
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEHHHHHHHHHCCHHHHHHHCCCCH
GAALNLLVPVPIPAIVVGAAAAILSLQIFGSYALLRDIFRWLALALFAYVAAAILARPDP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
AEILRGTLVPQVRFDADFLAMIVACIGTSLSAYIYTWQSNQEVEEEIALGRRTLRQRNGA
HHHHHHHCCCCEECCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCC
TDAELRKTRRDVMIGMLFSNIILYFIVLSTGATLHQAGQTEIESAAQAAAALEPLAGAGA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCH
KYLFALGVVGVGFLAVPVMTTGAAYDLVQGIGRTGSLHARPSEAKLFYGTIAAVTVLAVG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LNFLGFNPMRALVWSGIVQGFSVPPLLLLMMLMTNDRAVMGGRVNGRVTNGLGWLTTAAT
HHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEECCCCCCEEECCHHHHHHHHH
FLATLCLVGTWVL
HHHHHHHHHHHCC
>Mature Secondary Structure
MDQPRPKPDTDDPDRPRGRGSLLHALGTGVITGAADDDPSAIGTYASAGARYGLGFLWIA
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCEEECCCCCCCHHHHHHHHCCHHHCHHHHHHH
PVVLPMMVVVVYLSAKLGQVYGKGLFAIVRDRYPRWVLYPLVAGAFGGNVIEAAANLGGI
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEHHHHHHHHHCCHHHHHHHCCCCH
GAALNLLVPVPIPAIVVGAAAAILSLQIFGSYALLRDIFRWLALALFAYVAAAILARPDP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
AEILRGTLVPQVRFDADFLAMIVACIGTSLSAYIYTWQSNQEVEEEIALGRRTLRQRNGA
HHHHHHHCCCCEECCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCC
TDAELRKTRRDVMIGMLFSNIILYFIVLSTGATLHQAGQTEIESAAQAAAALEPLAGAGA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCH
KYLFALGVVGVGFLAVPVMTTGAAYDLVQGIGRTGSLHARPSEAKLFYGTIAAVTVLAVG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LNFLGFNPMRALVWSGIVQGFSVPPLLLLMMLMTNDRAVMGGRVNGRVTNGLGWLTTAAT
HHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEECCCCCCEEECCHHHHHHHHH
FLATLCLVGTWVL
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]