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The map label for this gene is ndh [H]

Identifier: 170747144

GI number: 170747144

Start: 749396

End: 750676

Strand: Reverse

Name: ndh [H]

Synonym: Mrad2831_0710

Alternate gene names: 170747144

Gene position: 750676-749396 (Counterclockwise)

Preceding gene: 170747145

Following gene: 170747141

Centisome position: 12.35

GC content: 73.3

Gene sequence:

>1281_bases
ATGGCGGAGAGACCACGGATCGTGATCGTCGGCGGCGGCGTCGCCGGTATCGAGGTGGCCACGAGCCTCGGACGCGGCGG
GCGGGCCGACGTCACCCTCGCCGATCGCAGCCTCTCGCATGTCTGGAAGCCGATGCTGCACACCTTCGCGGCCGGCACCG
CCCGGGCCGACCGGCAGAAGGTGGACTTCTTCGCCCAGGCGCGCCGCAACGGCTTCCGTTTCCAGCCCGGCGCCCTCGTC
GGCATCGACCGGCAAGCCAGGCGCGTCCGGCTCGCGGTCGAGGCCGCGGAGGGGCTCCCGGAGGTGGAGCGCGCCTACGA
CCTGCTGGTGCTCGCCATCGGCAGCCGCGCCAACGATTTCGGCACGCCGGGCGTGTCCGAGCATTGCCTGACGATCGACG
ACCTGACCGAGGCCGAGCACTTCCACCAACAGCTGCGGTGCCATCTCCTGGCCCGGCTCGACGGCGGCGGTCTGCTGCAG
ATCGCCATCGTCGGCGGCGGTGCGACCGGTGTCGAGCTGGCCGCCGAGCTCAAGCACGCCATCAACCTCCTCGCCGACTA
CGGCTCGCCCGACCTGCCGGGGCGCCTGCGCCTGACGCTGATCGAGAGCGGGCCGCGCCTGCTGCCGGCCTTCCCCGACA
AGGTCTCCCGCGCCGCCGCCCGCACGCTGTCGGATCTCGACGTGGAGGTCCGGACCAACGCGACGGTGACGGCGGCGGAC
GCGCAGGGATTCGTCCTGAAGGACGGCAGCCGCATCCCGGCCGGGCTGAAGGTCTGGGCCGCCGGCGTGAAGGCGCCGGA
CGTGCTCGCCGGCCTCGACGGCCTGGAGCGCTCCCGGACCGGGCAGCTCGTCGTCCGCCCGGACCTGCGCACGACCCGGG
ATCCGGCCATCGTCGCCCTCGGCGACTGTTCAAGCCTCACCGATCCCCGGACCGGCCGACCCGTACCGGCGACCGCGCAG
GCCGCCCGCCAGGAGGCGCAGCACCTCGCGCGGCATCTCGGCCGCGCGCTGGCGCGCGGGGACGGGACGGCCTCGGACCT
GCCGCCGTTCCACTACGTCGAGAAGGGCGCGATCGTCTCGCTGGCCGACTTCAACGGCTGGGGAACCCTCGGCCGCTACA
CCTTCGGCGGCGGGCACCTCAACGGGCTCTCGGCGCGGCTGACGCACGACCTCCTGTACCGGCAGCACCAGATCGGGCTC
TACGGGCCGCTGCGCGGGACGATGACGTGGGTCCTCGACGATCTTGACCACCTGATCAGCCCGCCGGTGCGGCTCGACTG
A

Upstream 100 bases:

>100_bases
GCGCAAGAGGTGCTGCCGACGACGGGCGGGATCGGCGCGGCCCGCGGCGAACACCGAGGCCGTGACCGGCGTTCCCGATC
GGTGAGGATGCGGAGACGTC

Downstream 100 bases:

>100_bases
GGCGGCCGGCGCGGATCCGGAGTCCCGGGGGCCGCGCCGTGCCGGCAGCGGCTCGTGCCGGCGATCCGCGTCCCGCGGCC
TCAATCCGGCCGTTCGCCCT

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MAERPRIVIVGGGVAGIEVATSLGRGGRADVTLADRSLSHVWKPMLHTFAAGTARADRQKVDFFAQARRNGFRFQPGALV
GIDRQARRVRLAVEAAEGLPEVERAYDLLVLAIGSRANDFGTPGVSEHCLTIDDLTEAEHFHQQLRCHLLARLDGGGLLQ
IAIVGGGATGVELAAELKHAINLLADYGSPDLPGRLRLTLIESGPRLLPAFPDKVSRAAARTLSDLDVEVRTNATVTAAD
AQGFVLKDGSRIPAGLKVWAAGVKAPDVLAGLDGLERSRTGQLVVRPDLRTTRDPAIVALGDCSSLTDPRTGRPVPATAQ
AARQEAQHLARHLGRALARGDGTASDLPPFHYVEKGAIVSLADFNGWGTLGRYTFGGGHLNGLSARLTHDLLYRQHQIGL
YGPLRGTMTWVLDDLDHLISPPVRLD

Sequences:

>Translated_426_residues
MAERPRIVIVGGGVAGIEVATSLGRGGRADVTLADRSLSHVWKPMLHTFAAGTARADRQKVDFFAQARRNGFRFQPGALV
GIDRQARRVRLAVEAAEGLPEVERAYDLLVLAIGSRANDFGTPGVSEHCLTIDDLTEAEHFHQQLRCHLLARLDGGGLLQ
IAIVGGGATGVELAAELKHAINLLADYGSPDLPGRLRLTLIESGPRLLPAFPDKVSRAAARTLSDLDVEVRTNATVTAAD
AQGFVLKDGSRIPAGLKVWAAGVKAPDVLAGLDGLERSRTGQLVVRPDLRTTRDPAIVALGDCSSLTDPRTGRPVPATAQ
AARQEAQHLARHLGRALARGDGTASDLPPFHYVEKGAIVSLADFNGWGTLGRYTFGGGHLNGLSARLTHDLLYRQHQIGL
YGPLRGTMTWVLDDLDHLISPPVRLD
>Mature_425_residues
AERPRIVIVGGGVAGIEVATSLGRGGRADVTLADRSLSHVWKPMLHTFAAGTARADRQKVDFFAQARRNGFRFQPGALVG
IDRQARRVRLAVEAAEGLPEVERAYDLLVLAIGSRANDFGTPGVSEHCLTIDDLTEAEHFHQQLRCHLLARLDGGGLLQI
AIVGGGATGVELAAELKHAINLLADYGSPDLPGRLRLTLIESGPRLLPAFPDKVSRAAARTLSDLDVEVRTNATVTAADA
QGFVLKDGSRIPAGLKVWAAGVKAPDVLAGLDGLERSRTGQLVVRPDLRTTRDPAIVALGDCSSLTDPRTGRPVPATAQA
ARQEAQHLARHLGRALARGDGTASDLPPFHYVEKGAIVSLADFNGWGTLGRYTFGGGHLNGLSARLTHDLLYRQHQIGLY
GPLRGTMTWVLDDLDHLISPPVRLD

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=433, Percent_Identity=44.3418013856813, Blast_Score=318, Evalue=6e-88,
Organism=Saccharomyces cerevisiae, GI6323794, Length=400, Percent_Identity=25.25, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6320118, Length=355, Percent_Identity=25.0704225352113, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323515, Length=461, Percent_Identity=24.0780911062907, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 45501; Mature: 45370

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERPRIVIVGGGVAGIEVATSLGRGGRADVTLADRSLSHVWKPMLHTFAAGTARADRQK
CCCCCEEEEEECCCHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHH
VDFFAQARRNGFRFQPGALVGIDRQARRVRLAVEAAEGLPEVERAYDLLVLAIGSRANDF
HHHHHHHHHCCCEECCCCEEECCHHHHHEEEEEEHHHCCHHHHHHHEEEEEEECCCCCCC
GTPGVSEHCLTIDDLTEAEHFHQQLRCHLLARLDGGGLLQIAIVGGGATGVELAAELKHA
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEECCCCHHHHHHHHHHHH
INLLADYGSPDLPGRLRLTLIESGPRLLPAFPDKVSRAAARTLSDLDVEVRTNATVTAAD
HHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEECCCEEEEEC
AQGFVLKDGSRIPAGLKVWAAGVKAPDVLAGLDGLERSRTGQLVVRPDLRTTRDPAIVAL
CCCEEEECCCCCCCCCEEEECCCCCCHHHHCCCCCCCCCCCCEEECCCCCCCCCCEEEEE
GDCSSLTDPRTGRPVPATAQAARQEAQHLARHLGRALARGDGTASDLPPFHYVEKGAIVS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCEEE
LADFNGWGTLGRYTFGGGHLNGLSARLTHDLLYRQHQIGLYGPLRGTMTWVLDDLDHLIS
EECCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHC
PPVRLD
CCCCCC
>Mature Secondary Structure 
AERPRIVIVGGGVAGIEVATSLGRGGRADVTLADRSLSHVWKPMLHTFAAGTARADRQK
CCCCEEEEEECCCHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHH
VDFFAQARRNGFRFQPGALVGIDRQARRVRLAVEAAEGLPEVERAYDLLVLAIGSRANDF
HHHHHHHHHCCCEECCCCEEECCHHHHHEEEEEEHHHCCHHHHHHHEEEEEEECCCCCCC
GTPGVSEHCLTIDDLTEAEHFHQQLRCHLLARLDGGGLLQIAIVGGGATGVELAAELKHA
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEECCCCHHHHHHHHHHHH
INLLADYGSPDLPGRLRLTLIESGPRLLPAFPDKVSRAAARTLSDLDVEVRTNATVTAAD
HHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEECCCEEEEEC
AQGFVLKDGSRIPAGLKVWAAGVKAPDVLAGLDGLERSRTGQLVVRPDLRTTRDPAIVAL
CCCEEEECCCCCCCCCEEEECCCCCCHHHHCCCCCCCCCCCCEEECCCCCCCCCCEEEEE
GDCSSLTDPRTGRPVPATAQAARQEAQHLARHLGRALARGDGTASDLPPFHYVEKGAIVS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCEEE
LADFNGWGTLGRYTFGGGHLNGLSARLTHDLLYRQHQIGLYGPLRGTMTWVLDDLDHLIS
EECCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHC
PPVRLD
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]