Click here to switch to the map view.

The map label for this gene is mocR [H]

Identifier: 170747095

GI number: 170747095

Start: 706602

End: 708143

Strand: Reverse

Name: mocR [H]

Synonym: Mrad2831_0661

Alternate gene names: 170747095

Gene position: 708143-706602 (Counterclockwise)

Preceding gene: 170747098

Following gene: 170747085

Centisome position: 11.65

GC content: 78.47

Gene sequence:

>1542_bases
ATGGCCCGGGCTCCCCTGCCCCTGACGCTGACCCTCAACGCCGCGGCCGCGGCGCCGCTGCACGCCCAGCTCCGGGAGGC
TCTGCGCGCGGCGATCCTCGAACGCCGGCTGCCGCGCGGGGCCCGGCTCCCGGCCTCGCGGGTCCTGGCCGCCGACCTCG
GCTGCGCGCGCGGCACCGTCGTCCTGGCGCTGGAGCAGCTGACCGCCGAGGGCTACCTGACGGCGCGGCCGGGCTCCGCG
ACGCGCGTCGCCGCGACCTTGCCGGACGACGCGCTGCCGGCGCCCGGTCCGCTCCGGCGGCCGGGCACCGAGCCGGCCCC
GAACCTGTCCCGGCGGGGCACCCGCCTCGTGGCCGCGCCGCCGCGGCGCTACATGGCGGGTCCGGCGGTGCCCGACGCTT
TCGCCCTCGGCCGGCCGGCCCAGGACGCCTTTCCGTTCGAGGTCTGGGGCCGCCTGCTGCAGGCCGAATGGCGCCACGGC
CCGACCGAGCGGCCGGACCCGCGCGGCTCGCCGGCCCTGCGCGGCGCCATCGCCGCCTATCTGGGCCAAGCGCGCGGCGT
CGCCTGCGAGGCCGACGACGTCATCGTCACCGCGGGCATCCGCCAGAGCCTGCGCCTGCTCGCCGAGCTGCTCCTGGATC
CCGGCGAGGCCGCCCTGGTCGAGGAGCCCGGCTTCCCCGGCATCGCGCAGGCCCTCGCCAGCGCGGGCCTGAACCCGATC
CCTGTCCCGGTCGGTCCCGGGGGCCTGTCGGTGACCCCGGCCGCCGCGCGGACGCCCGGCGCGCGGCTCGCGGTGGTGAC
GCCGGCCCACCATTACCCCCTCGGGCACGCCATGAGCCTGGAGAACCGCCTCGACCTCCTGGCCTGGGCCGAGGCGGTCT
CGGGCTGGGTCGTGGAGGACGATTACGACGGCGCCTACCGCTATGCCGGGCGCCCGCTCGCGCCCCTGCGCACCCTCGAT
CGCGGCGGCCGGGTGATCTACGTCGGCAGCTTCTCGAAGCTGCTGCTGCCCGCCCTCGGCCTGAGCTACCTCGTGCTGCC
CCGCGGCCTCGTGGCACCCGTCAATCAGGCGCTGGCCGAGACGGGCCCCGCCCCGCCCGGGATCGGCCAGTGGGCGCTGG
CGCGCTTCATCGAGGACGGACACCTCGCCGGTCATCTCCGGCGGACCCGCCGCCTCTACGCCCTGCGCCAGGAGGCGCTG
ATCGAGGCCGCGTGCCGCCACGCCGGGGACGTCGCGGCGGTCGCCGCCATGGAGGGCGGGATGCACGTCATCGCCCGGCC
GGGGCCGGCCTGGGGCCCGGCCCTGAGCGACGTGGCCGCCGCGGCGGCGCTCGGGCGCGCGGGGATCTCGGCGGTCGCGC
TCTCGGCCTACCACGCCGGGCCGGCGGAGCCGGGCCTGCTCCTCGGCTACGCCGCCGTGCCGGAGCGGGCGATCGAGCCG
GCCGTGCGGCGCTTGGCGGAGACCCTGCGCGGTGCGCCGGATCCCCGTCCGAACGGCCACCCTCGAGACGCGCTCAGTGC
ACGATCGCGCCCGTCTCCATGA

Upstream 100 bases:

>100_bases
ATGGGCCTGTCCTGCGGCGGTCGTGCGGACCCGTGCTTGACCGTTCGGCGGTCCAGGCGAAAGGTCCAATTCTCGAACTG
CGACTGGACCAATTCGCTGC

Downstream 100 bases:

>100_bases
ACCGGTTCAGCCGCTCGATCAGCGGCGCGACCATCACCCGCTCGAGCTGCGGCAGCAATCCGCGCCGCGCGTGGGCCACG
TTGGCCTCGGCCTGTTCCCG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MARAPLPLTLTLNAAAAAPLHAQLREALRAAILERRLPRGARLPASRVLAADLGCARGTVVLALEQLTAEGYLTARPGSA
TRVAATLPDDALPAPGPLRRPGTEPAPNLSRRGTRLVAAPPRRYMAGPAVPDAFALGRPAQDAFPFEVWGRLLQAEWRHG
PTERPDPRGSPALRGAIAAYLGQARGVACEADDVIVTAGIRQSLRLLAELLLDPGEAALVEEPGFPGIAQALASAGLNPI
PVPVGPGGLSVTPAAARTPGARLAVVTPAHHYPLGHAMSLENRLDLLAWAEAVSGWVVEDDYDGAYRYAGRPLAPLRTLD
RGGRVIYVGSFSKLLLPALGLSYLVLPRGLVAPVNQALAETGPAPPGIGQWALARFIEDGHLAGHLRRTRRLYALRQEAL
IEAACRHAGDVAAVAAMEGGMHVIARPGPAWGPALSDVAAAAALGRAGISAVALSAYHAGPAEPGLLLGYAAVPERAIEP
AVRRLAETLRGAPDPRPNGHPRDALSARSRPSP

Sequences:

>Translated_513_residues
MARAPLPLTLTLNAAAAAPLHAQLREALRAAILERRLPRGARLPASRVLAADLGCARGTVVLALEQLTAEGYLTARPGSA
TRVAATLPDDALPAPGPLRRPGTEPAPNLSRRGTRLVAAPPRRYMAGPAVPDAFALGRPAQDAFPFEVWGRLLQAEWRHG
PTERPDPRGSPALRGAIAAYLGQARGVACEADDVIVTAGIRQSLRLLAELLLDPGEAALVEEPGFPGIAQALASAGLNPI
PVPVGPGGLSVTPAAARTPGARLAVVTPAHHYPLGHAMSLENRLDLLAWAEAVSGWVVEDDYDGAYRYAGRPLAPLRTLD
RGGRVIYVGSFSKLLLPALGLSYLVLPRGLVAPVNQALAETGPAPPGIGQWALARFIEDGHLAGHLRRTRRLYALRQEAL
IEAACRHAGDVAAVAAMEGGMHVIARPGPAWGPALSDVAAAAALGRAGISAVALSAYHAGPAEPGLLLGYAAVPERAIEP
AVRRLAETLRGAPDPRPNGHPRDALSARSRPSP
>Mature_512_residues
ARAPLPLTLTLNAAAAAPLHAQLREALRAAILERRLPRGARLPASRVLAADLGCARGTVVLALEQLTAEGYLTARPGSAT
RVAATLPDDALPAPGPLRRPGTEPAPNLSRRGTRLVAAPPRRYMAGPAVPDAFALGRPAQDAFPFEVWGRLLQAEWRHGP
TERPDPRGSPALRGAIAAYLGQARGVACEADDVIVTAGIRQSLRLLAELLLDPGEAALVEEPGFPGIAQALASAGLNPIP
VPVGPGGLSVTPAAARTPGARLAVVTPAHHYPLGHAMSLENRLDLLAWAEAVSGWVVEDDYDGAYRYAGRPLAPLRTLDR
GGRVIYVGSFSKLLLPALGLSYLVLPRGLVAPVNQALAETGPAPPGIGQWALARFIEDGHLAGHLRRTRRLYALRQEALI
EAACRHAGDVAAVAAMEGGMHVIARPGPAWGPALSDVAAAAALGRAGISAVALSAYHAGPAEPGLLLGYAAVPERAIEPA
VRRLAETLRGAPDPRPNGHPRDALSARSRPSP

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=231, Percent_Identity=24.2424242424242, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI33469970, Length=231, Percent_Identity=24.2424242424242, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1787710, Length=404, Percent_Identity=27.2277227722772, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790797, Length=385, Percent_Identity=27.5324675324675, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53407; Mature: 53276

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARAPLPLTLTLNAAAAAPLHAQLREALRAAILERRLPRGARLPASRVLAADLGCARGTV
CCCCCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHH
VLALEQLTAEGYLTARPGSATRVAATLPDDALPAPGPLRRPGTEPAPNLSRRGTRLVAAP
EEEHHHHCCCCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEECC
PRRYMAGPAVPDAFALGRPAQDAFPFEVWGRLLQAEWRHGPTERPDPRGSPALRGAIAAY
CHHHCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
LGQARGVACEADDVIVTAGIRQSLRLLAELLLDPGEAALVEEPGFPGIAQALASAGLNPI
HHHHCCCEECCCCEEEEHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCCC
PVPVGPGGLSVTPAAARTPGARLAVVTPAHHYPLGHAMSLENRLDLLAWAEAVSGWVVED
CCCCCCCCCEECCCCCCCCCCEEEEECCCCCCCCCCHHCHHHHHHHHHHHHHHCCCEEEC
DYDGAYRYAGRPLAPLRTLDRGGRVIYVGSFSKLLLPALGLSYLVLPRGLVAPVNQALAE
CCCCHHHHCCCCCHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TGPAPPGIGQWALARFIEDGHLAGHLRRTRRLYALRQEALIEAACRHAGDVAAVAAMEGG
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
MHVIARPGPAWGPALSDVAAAAALGRAGISAVALSAYHAGPAEPGLLLGYAAVPERAIEP
EEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEHHCCHHHHHH
AVRRLAETLRGAPDPRPNGHPRDALSARSRPSP
HHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCC
>Mature Secondary Structure 
ARAPLPLTLTLNAAAAAPLHAQLREALRAAILERRLPRGARLPASRVLAADLGCARGTV
CCCCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHH
VLALEQLTAEGYLTARPGSATRVAATLPDDALPAPGPLRRPGTEPAPNLSRRGTRLVAAP
EEEHHHHCCCCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEECC
PRRYMAGPAVPDAFALGRPAQDAFPFEVWGRLLQAEWRHGPTERPDPRGSPALRGAIAAY
CHHHCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
LGQARGVACEADDVIVTAGIRQSLRLLAELLLDPGEAALVEEPGFPGIAQALASAGLNPI
HHHHCCCEECCCCEEEEHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCCC
PVPVGPGGLSVTPAAARTPGARLAVVTPAHHYPLGHAMSLENRLDLLAWAEAVSGWVVED
CCCCCCCCCEECCCCCCCCCCEEEEECCCCCCCCCCHHCHHHHHHHHHHHHHHCCCEEEC
DYDGAYRYAGRPLAPLRTLDRGGRVIYVGSFSKLLLPALGLSYLVLPRGLVAPVNQALAE
CCCCHHHHCCCCCHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TGPAPPGIGQWALARFIEDGHLAGHLRRTRRLYALRQEALIEAACRHAGDVAAVAAMEGG
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCC
MHVIARPGPAWGPALSDVAAAAALGRAGISAVALSAYHAGPAEPGLLLGYAAVPERAIEP
EEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEHHCCHHHHHH
AVRRLAETLRGAPDPRPNGHPRDALSARSRPSP
HHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]