Click here to switch to the map view.

The map label for this gene is atpD [H]

Identifier: 170747037

GI number: 170747037

Start: 645591

End: 647045

Strand: Reverse

Name: atpD [H]

Synonym: Mrad2831_0603

Alternate gene names: 170747037

Gene position: 647045-645591 (Counterclockwise)

Preceding gene: 170747038

Following gene: 170747036

Centisome position: 10.65

GC content: 68.04

Gene sequence:

>1455_bases
ATGGCGAACACCGCACTCCCCGGCACCGGCTCCAACAAGGTCGGCAAGATCACCCAGGTCATCGGCCCCGTGGTCGACGT
GCAGTTCGAGGGCCACCTGCCCGAGATCCTGAACGCCCTTGAGACCAAGAACAACGGCGCCCGCCTCGTCCTCGAGGTCG
CCCAGCAGCTCGGCGAGAACACCGTCCGCTGCATCGCCATGGACACGTCGGAGGGCCTGACCCGCGGCCAGGAGTGCACC
GACACCGGCGAGCCGATCAAGGTTCCCGTCGGCATGAATACCCTCGGCCGCATCATGAACGTCATCGGCGAGCCGATCGA
CGAGGCCGGCCCGGTCCAGGCCACCACCTACCGCGCCATCCACCAGCCGGCCCCCTCCTACGCCGAGCAGTCGACCGAGG
CACAGATCCTCGTCACCGGCATCAAGGTGGTGGACCTGCTCGCCCCCTACGCCAAGGGCGGCAAGATCGGCCTGTTCGGC
GGCGCCGGCGTCGGCAAGACCGTGCTGATCATGGAGCTGATCAACAACATCGCGAAGGTGCACTCGGGCTACTCGGTCTT
CGCCGGCGTGGGTGAGCGCACCCGCGAGGGCAACGACCTCTACCACGAGATGATCGAGTCCAAGGTGAACGTCGACCCGA
AGGAGCACGGCTCCGCCGAGGGCTCGAAGTGCGCCCTGGTCTACGGCCAGATGAACGAGTCGCCCGGCGCCCGCTCGCGC
GTCGCCCTGACCGGCCTGACCATCGCCGAGCAGTTCCGCGACGACGGCCAGGACGTGCTGTTCTTCGTCGACAACATCTT
CCGCTTCACGCAGGCGGGCTCCGAGGTGTCGGCGCTCCTCGGCCGCATCCCCTCGGCGGTGGGCTACCAGCCGACCCTCG
CCACCGACATGGGCGCCCTCCAGGAGCGCATCACCACCACGACCAAGGGCTCGATCACCTCGGTGCAGGCCATCTACGTG
CCGGCCGACGACCTGACCGACCCGGCGCCCGCCGCCTCCTTCGCCCACCTCGACGCCACGACCGTGCTGTCGCGCTCGAT
CGCCGAGAAGGGCATCTACCCGGCGGTGGATCCGCTGGACTCGACCTCGCGCATGCTGTCGCCGGCGATCCTCGGCGAGG
AGCACTACGACGTCGCCCGCCGCGTCCAGCAGACCCTGCAGCGCTACAAGGCGCTCCAGGACATCATCGCGATCCTGGGC
ATGGACGAGCTGTCCGAGGAGGATAAGCTGACCGTCGCCCGCGCCCGCAAGATCGAGCGCTTCTTCTCGCAGCCCTTCTC
CGTCGCCGAGGTCTTCACCGGCTCGCCGGGCAAGCAGGTGGCGCTGGAAGACACCATCAAGGGCTTCAAGGGCCTGGTGA
ACGGCGACTACGACGACCTCCCGGAGGCCGCCTTCTACATGGTCGGCACCATCGAGGAGGCCCAGGAGAAGGCCAAGAAG
CTCAAGGCCGCGTAA

Upstream 100 bases:

>100_bases
TCAGGCCATGATCACCAAGGAACTCATCGAGATCATCTCGGGCGCGGAAGCCCTCTGAGGCACCGCGACCCGACCGCACA
GCTTGAAGGGTAGGTTTACC

Downstream 100 bases:

>100_bases
GACGACATCCCCCCTTCCCCGCGCGGGAAGGGGGCAGAGGCTGCGCGGGCGACCCTCACCGGTGCCGTCCGCGCAGCCTT
TTCCGAGACGCTCCGCCCGC

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta [H]

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MANTALPGTGSNKVGKITQVIGPVVDVQFEGHLPEILNALETKNNGARLVLEVAQQLGENTVRCIAMDTSEGLTRGQECT
DTGEPIKVPVGMNTLGRIMNVIGEPIDEAGPVQATTYRAIHQPAPSYAEQSTEAQILVTGIKVVDLLAPYAKGGKIGLFG
GAGVGKTVLIMELINNIAKVHSGYSVFAGVGERTREGNDLYHEMIESKVNVDPKEHGSAEGSKCALVYGQMNESPGARSR
VALTGLTIAEQFRDDGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITTTTKGSITSVQAIYV
PADDLTDPAPAASFAHLDATTVLSRSIAEKGIYPAVDPLDSTSRMLSPAILGEEHYDVARRVQQTLQRYKALQDIIAILG
MDELSEEDKLTVARARKIERFFSQPFSVAEVFTGSPGKQVALEDTIKGFKGLVNGDYDDLPEAAFYMVGTIEEAQEKAKK
LKAA

Sequences:

>Translated_484_residues
MANTALPGTGSNKVGKITQVIGPVVDVQFEGHLPEILNALETKNNGARLVLEVAQQLGENTVRCIAMDTSEGLTRGQECT
DTGEPIKVPVGMNTLGRIMNVIGEPIDEAGPVQATTYRAIHQPAPSYAEQSTEAQILVTGIKVVDLLAPYAKGGKIGLFG
GAGVGKTVLIMELINNIAKVHSGYSVFAGVGERTREGNDLYHEMIESKVNVDPKEHGSAEGSKCALVYGQMNESPGARSR
VALTGLTIAEQFRDDGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITTTTKGSITSVQAIYV
PADDLTDPAPAASFAHLDATTVLSRSIAEKGIYPAVDPLDSTSRMLSPAILGEEHYDVARRVQQTLQRYKALQDIIAILG
MDELSEEDKLTVARARKIERFFSQPFSVAEVFTGSPGKQVALEDTIKGFKGLVNGDYDDLPEAAFYMVGTIEEAQEKAKK
LKAA
>Mature_483_residues
ANTALPGTGSNKVGKITQVIGPVVDVQFEGHLPEILNALETKNNGARLVLEVAQQLGENTVRCIAMDTSEGLTRGQECTD
TGEPIKVPVGMNTLGRIMNVIGEPIDEAGPVQATTYRAIHQPAPSYAEQSTEAQILVTGIKVVDLLAPYAKGGKIGLFGG
AGVGKTVLIMELINNIAKVHSGYSVFAGVGERTREGNDLYHEMIESKVNVDPKEHGSAEGSKCALVYGQMNESPGARSRV
ALTGLTIAEQFRDDGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITTTTKGSITSVQAIYVP
ADDLTDPAPAASFAHLDATTVLSRSIAEKGIYPAVDPLDSTSRMLSPAILGEEHYDVARRVQQTLQRYKALQDIIAILGM
DELSEEDKLTVARARKIERFFSQPFSVAEVFTGSPGKQVALEDTIKGFKGLVNGDYDDLPEAAFYMVGTIEEAQEKAKKL
KAA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=468, Percent_Identity=76.4957264957265, Blast_Score=710, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=303, Percent_Identity=28.3828382838284, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI19913426, Length=405, Percent_Identity=26.4197530864197, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI19913428, Length=413, Percent_Identity=27.1186440677966, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI50345984, Length=321, Percent_Identity=23.98753894081, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4757810, Length=321, Percent_Identity=23.98753894081, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1790170, Length=468, Percent_Identity=69.6581196581197, Blast_Score=652, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=362, Percent_Identity=30.3867403314917, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1790172, Length=329, Percent_Identity=26.7477203647416, Blast_Score=105, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=474, Percent_Identity=73.2067510548523, Blast_Score=703, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17565854, Length=325, Percent_Identity=28, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17510931, Length=358, Percent_Identity=25.6983240223464, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17570191, Length=363, Percent_Identity=26.9972451790634, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71988080, Length=328, Percent_Identity=23.1707317073171, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71988063, Length=328, Percent_Identity=24.0853658536585, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71988074, Length=280, Percent_Identity=23.9285714285714, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322581, Length=462, Percent_Identity=74.2424242424242, Blast_Score=683, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=361, Percent_Identity=28.808864265928, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6319370, Length=363, Percent_Identity=25.6198347107438, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320016, Length=260, Percent_Identity=25, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24638766, Length=468, Percent_Identity=76.7094017094017, Blast_Score=715, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=472, Percent_Identity=71.3983050847458, Blast_Score=676, Evalue=0.0,
Organism=Drosophila melanogaster, GI24638768, Length=90, Percent_Identity=70, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24583988, Length=327, Percent_Identity=27.82874617737, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24583986, Length=327, Percent_Identity=27.82874617737, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24583984, Length=327, Percent_Identity=27.82874617737, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24583992, Length=327, Percent_Identity=27.82874617737, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI20129479, Length=313, Percent_Identity=27.4760383386581, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281361666, Length=368, Percent_Identity=27.445652173913, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24646341, Length=368, Percent_Identity=27.445652173913, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17136796, Length=368, Percent_Identity=27.445652173913, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24658560, Length=328, Percent_Identity=23.780487804878, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 51816; Mature: 51685

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTALPGTGSNKVGKITQVIGPVVDVQFEGHLPEILNALETKNNGARLVLEVAQQLGEN
CCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHCCC
TVRCIAMDTSEGLTRGQECTDTGEPIKVPVGMNTLGRIMNVIGEPIDEAGPVQATTYRAI
CEEEEEEECHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
HQPAPSYAEQSTEAQILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNIAKV
HCCCCCHHHCCCCCEEEEHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHH
HSGYSVFAGVGERTREGNDLYHEMIESKVNVDPKEHGSAEGSKCALVYGQMNESPGARSR
HCCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHCCCCCCCEEEEEEECCCCCCCCCCE
VALTGLTIAEQFRDDGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGAL
EEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCCHHHHHHHH
QERITTTTKGSITSVQAIYVPADDLTDPAPAASFAHLDATTVLSRSIAEKGIYPAVDPLD
HHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
STSRMLSPAILGEEHYDVARRVQQTLQRYKALQDIIAILGMDELSEEDKLTVARARKIER
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHH
FFSQPFSVAEVFTGSPGKQVALEDTIKGFKGLVNGDYDDLPEAAFYMVGTIEEAQEKAKK
HHCCCCCHHHHHCCCCCCEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LKAA
HCCC
>Mature Secondary Structure 
ANTALPGTGSNKVGKITQVIGPVVDVQFEGHLPEILNALETKNNGARLVLEVAQQLGEN
CCCCCCCCCCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHCCC
TVRCIAMDTSEGLTRGQECTDTGEPIKVPVGMNTLGRIMNVIGEPIDEAGPVQATTYRAI
CEEEEEEECHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
HQPAPSYAEQSTEAQILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNIAKV
HCCCCCHHHCCCCCEEEEHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHH
HSGYSVFAGVGERTREGNDLYHEMIESKVNVDPKEHGSAEGSKCALVYGQMNESPGARSR
HCCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHCCCCCCCEEEEEEECCCCCCCCCCE
VALTGLTIAEQFRDDGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGAL
EEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCCHHHHHHHH
QERITTTTKGSITSVQAIYVPADDLTDPAPAASFAHLDATTVLSRSIAEKGIYPAVDPLD
HHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
STSRMLSPAILGEEHYDVARRVQQTLQRYKALQDIIAILGMDELSEEDKLTVARARKIER
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHH
FFSQPFSVAEVFTGSPGKQVALEDTIKGFKGLVNGDYDDLPEAAFYMVGTIEEAQEKAKK
HHCCCCCHHHHHCCCCCCEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LKAA
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA