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The map label for this gene is bdlA [H]

Identifier: 170746827

GI number: 170746827

Start: 423916

End: 425376

Strand: Reverse

Name: bdlA [H]

Synonym: Mrad2831_0385

Alternate gene names: 170746827

Gene position: 425376-423916 (Counterclockwise)

Preceding gene: 170746828

Following gene: 170746826

Centisome position: 7.0

GC content: 64.75

Gene sequence:

>1461_bases
ATGTTCCGTAAGCCCGCCTTTGATGAGAACCAAGCCACCATCGACGCGCTGACGCGCTCGTTGGCTATCATCGAGTTCGG
CATGGATGGTACCATCCTGCGCGCCAACCCGAATTTCCTGGCCGTCGTGGACTACGATCTCGCTTCCCTGCAGGGTAAGC
ACCACCGGATCCTAGTCAGCGAGGAGACGGCCAACGGTCCGGAGTATGATGAATTCTGGTCGAAGCTGCGGGCCGGCGAA
TTCATGTCCGGTGAGTTCCCCCGCCGCGCGCGGTCCGGCGCGAGGGTCTGGCTCGAAGCCACCTACAACCCGATCCTGGG
CTCCGACGGCAAGCCGTTCAAGGTCATCAAGTTCGCCAGCGACATCACGGCCAAGAAGAGCGAGACCAACCGGCTGCTGC
GCATGATCGACGAGATGCCGGTCGCCGTCATGACCGCGGATCCGAAGAACGATTTCAAGATCAATTACATCAACAACACC
TCGCGCAAGACTCTGGAAGCCATCGAGCGGCATCTGCCGATCAAGGTCTCCGAGATGATGGGCAAGTCCTTCGACGTGTT
CCACAAGAACCCGCATCACCAGCGGAACATGCTCGCCGACGCGCGCCGACTGCCCCACCGCACCAAGATCAAGGTCGGAC
CCGAGACCCTCGATCTGCAGGTCTCCGCCATCACCGACGCGGACGGAGCCTATGTCGGGCCGATGTTGACATGGTCGGTC
ATCACCGCACAACTCGCCATGGCCGAGGACGTCGCCGGCGTCGTCGAGGCGCTCGGGACCGCGATCGGCGAGATGAAGGA
GTCGGCGGAGGGCCTGAACCGCTCGGCGGACGCGGCGAGCGAGCGCGCGAACTCCGTGGCGGCCGGATCCGAGGAGATGA
CCAGCTCGATCCACGAGATCTCGGGTCAAGTCGGGCGGGTCTCCGAGCGTACCCAGCAGATCGCCAGCCAGGCGACGGCG
ACGGACGTGACGGTTCGCAACCTCGCCGCCAATGCCGGCGAGGTCGACGCGGTGGTCGGAATGATCAAGTCTATCGCCGA
CCAGACCAATCTTCTCGCACTCAACGCCACGATCGAGGCGGCGCGCGCGGGTGCGGCCGGTCGTGGCTTCGCGGTAGTGG
CCACGGAGGTCAAGGAGCTTGCCGGCCAGACGGCGAGAGCGACCGGCGAGATCACGCACAAGGTCCACGCCATCCAGAAG
GCGACCGGCGAGGCCGTGACGGCGATCCGCTTGATCACCGACGAGGTGGCCGAGCTCTCGAAACTCACGCTGGCCATGGC
GAGCGCCGTCGAGGAGCAGGCCGCCTCGACCCAGGAGATGTCGTCCAACATCACCGGTGTCTCGGCCGCGGCCGGAGAGA
CGGGACAGCTCGCAGAGATGGTCCGGCGGATCTCCGACAAGCTCGAGGCGCATTCCGCCGGCCTCGGTGCCAGCATGGAG
AAGTACCTCAAGGCGAGTTGA

Upstream 100 bases:

>100_bases
TGGAACGTGGTGGCGCACGGTCCGAGCCGGATTCCGAGATGCGACTAAGACCAACTTATGGTCTCGATGTCACGATACGG
CGTCCAATGAGAGTTGCGCC

Downstream 100 bases:

>100_bases
TGAAAGCATAAGGAGGCCCTTCCAGCTATCTGCTTTAGGCTCTCCGAGGGGAGCTGAAGCGAGCGCTGCTCCGTCGATCC
TTCTGGGAGGCGCCGAGGTG

Product: methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MFRKPAFDENQATIDALTRSLAIIEFGMDGTILRANPNFLAVVDYDLASLQGKHHRILVSEETANGPEYDEFWSKLRAGE
FMSGEFPRRARSGARVWLEATYNPILGSDGKPFKVIKFASDITAKKSETNRLLRMIDEMPVAVMTADPKNDFKINYINNT
SRKTLEAIERHLPIKVSEMMGKSFDVFHKNPHHQRNMLADARRLPHRTKIKVGPETLDLQVSAITDADGAYVGPMLTWSV
ITAQLAMAEDVAGVVEALGTAIGEMKESAEGLNRSADAASERANSVAAGSEEMTSSIHEISGQVGRVSERTQQIASQATA
TDVTVRNLAANAGEVDAVVGMIKSIADQTNLLALNATIEAARAGAAGRGFAVVATEVKELAGQTARATGEITHKVHAIQK
ATGEAVTAIRLITDEVAELSKLTLAMASAVEEQAASTQEMSSNITGVSAAAGETGQLAEMVRRISDKLEAHSAGLGASME
KYLKAS

Sequences:

>Translated_486_residues
MFRKPAFDENQATIDALTRSLAIIEFGMDGTILRANPNFLAVVDYDLASLQGKHHRILVSEETANGPEYDEFWSKLRAGE
FMSGEFPRRARSGARVWLEATYNPILGSDGKPFKVIKFASDITAKKSETNRLLRMIDEMPVAVMTADPKNDFKINYINNT
SRKTLEAIERHLPIKVSEMMGKSFDVFHKNPHHQRNMLADARRLPHRTKIKVGPETLDLQVSAITDADGAYVGPMLTWSV
ITAQLAMAEDVAGVVEALGTAIGEMKESAEGLNRSADAASERANSVAAGSEEMTSSIHEISGQVGRVSERTQQIASQATA
TDVTVRNLAANAGEVDAVVGMIKSIADQTNLLALNATIEAARAGAAGRGFAVVATEVKELAGQTARATGEITHKVHAIQK
ATGEAVTAIRLITDEVAELSKLTLAMASAVEEQAASTQEMSSNITGVSAAAGETGQLAEMVRRISDKLEAHSAGLGASME
KYLKAS
>Mature_486_residues
MFRKPAFDENQATIDALTRSLAIIEFGMDGTILRANPNFLAVVDYDLASLQGKHHRILVSEETANGPEYDEFWSKLRAGE
FMSGEFPRRARSGARVWLEATYNPILGSDGKPFKVIKFASDITAKKSETNRLLRMIDEMPVAVMTADPKNDFKINYINNT
SRKTLEAIERHLPIKVSEMMGKSFDVFHKNPHHQRNMLADARRLPHRTKIKVGPETLDLQVSAITDADGAYVGPMLTWSV
ITAQLAMAEDVAGVVEALGTAIGEMKESAEGLNRSADAASERANSVAAGSEEMTSSIHEISGQVGRVSERTQQIASQATA
TDVTVRNLAANAGEVDAVVGMIKSIADQTNLLALNATIEAARAGAAGRGFAVVATEVKELAGQTARATGEITHKVHAIQK
ATGEAVTAIRLITDEVAELSKLTLAMASAVEEQAASTQEMSSNITGVSAAAGETGQLAEMVRRISDKLEAHSAGLGASME
KYLKAS

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Integral Membrane. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=524, Percent_Identity=24.0458015267176, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1787690, Length=231, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788194, Length=187, Percent_Identity=31.5508021390374, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI2367378, Length=183, Percent_Identity=32.2404371584699, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788195, Length=189, Percent_Identity=29.6296296296296, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 52152; Mature: 52152

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRKPAFDENQATIDALTRSLAIIEFGMDGTILRANPNFLAVVDYDLASLQGKHHRILVS
CCCCCCCCCCHHHHHHHHHHHHEEEECCCCEEEEECCCEEEEEECHHHHCCCCCEEEEEE
EETANGPEYDEFWSKLRAGEFMSGEFPRRARSGARVWLEATYNPILGSDGKPFKVIKFAS
CCCCCCCCHHHHHHHHHCCCCCCCCCCHHHCCCCEEEEEEECCCCCCCCCCCEEEEEEHH
DITAKKSETNRLLRMIDEMPVAVMTADPKNDFKINYINNTSRKTLEAIERHLPIKVSEMM
HHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEECCCHHHHHHHHHHHCCEEHHHHC
GKSFDVFHKNPHHQRNMLADARRLPHRTKIKVGPETLDLQVSAITDADGAYVGPMLTWSV
CCCCHHHCCCCCHHHHHHHHHHHCCCCCEEEECCCEEEEEEEEEECCCCCEECHHHHHHH
ITAQLAMAEDVAGVVEALGTAIGEMKESAEGLNRSADAASERANSVAAGSEEMTSSIHEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
SGQVGRVSERTQQIASQATATDVTVRNLAANAGEVDAVVGMIKSIADQTNLLALNATIEA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEECHHHH
ARAGAAGRGFAVVATEVKELAGQTARATGEITHKVHAIQKATGEAVTAIRLITDEVAELS
HHCCCCCCCCEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
KLTLAMASAVEEQAASTQEMSSNITGVSAAAGETGQLAEMVRRISDKLEAHSAGLGASME
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
KYLKAS
HHHCCC
>Mature Secondary Structure
MFRKPAFDENQATIDALTRSLAIIEFGMDGTILRANPNFLAVVDYDLASLQGKHHRILVS
CCCCCCCCCCHHHHHHHHHHHHEEEECCCCEEEEECCCEEEEEECHHHHCCCCCEEEEEE
EETANGPEYDEFWSKLRAGEFMSGEFPRRARSGARVWLEATYNPILGSDGKPFKVIKFAS
CCCCCCCCHHHHHHHHHCCCCCCCCCCHHHCCCCEEEEEEECCCCCCCCCCCEEEEEEHH
DITAKKSETNRLLRMIDEMPVAVMTADPKNDFKINYINNTSRKTLEAIERHLPIKVSEMM
HHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEECCCHHHHHHHHHHHCCEEHHHHC
GKSFDVFHKNPHHQRNMLADARRLPHRTKIKVGPETLDLQVSAITDADGAYVGPMLTWSV
CCCCHHHCCCCCHHHHHHHHHHHCCCCCEEEECCCEEEEEEEEEECCCCCEECHHHHHHH
ITAQLAMAEDVAGVVEALGTAIGEMKESAEGLNRSADAASERANSVAAGSEEMTSSIHEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
SGQVGRVSERTQQIASQATATDVTVRNLAANAGEVDAVVGMIKSIADQTNLLALNATIEA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEECHHHH
ARAGAAGRGFAVVATEVKELAGQTARATGEITHKVHAIQKATGEAVTAIRLITDEVAELS
HHCCCCCCCCEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
KLTLAMASAVEEQAASTQEMSSNITGVSAAAGETGQLAEMVRRISDKLEAHSAGLGASME
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
KYLKAS
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]