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The map label for this gene is aroE [H]

Identifier: 170746780

GI number: 170746780

Start: 364490

End: 365299

Strand: Reverse

Name: aroE [H]

Synonym: Mrad2831_0333

Alternate gene names: 170746780

Gene position: 365299-364490 (Counterclockwise)

Preceding gene: 170746781

Following gene: 170746779

Centisome position: 6.01

GC content: 72.84

Gene sequence:

>810_bases
ATGAACAGCGCGCTCACGGCGGCCGGGATCACGGGACGGACGCGGGTCTACGGGATCCTGGCGGATCCGATCTACCACGT
GAAGGCGCCCGAGGTGATGGGGGCACTCTTCGCCCGTCACGGCGTGGACGGCGTCCTCGTCCCGCTGCACGTGACGGCGG
ACGGCCTGGCCGCGGTAGTGGACGGGCTCAGGCACCTGCGCAATTTCGGCGGCTTCATCGCCACGGTCCCGCACAAGACG
GCGACGACCGGCCTGTGCGACGCGCTCACCCGCGAGGCCGAGCAGATCGGGGCCGTCAACTGCGTCCGACGGGATGCGGA
CGGGCGCATGATCGGCACGATGCTGGACGGGATCGGATTCGTCGAGGCACTGCGCGTCTCCGGCCTGGAACCGCGCGGCC
GAAATGTTGCCCTCGCGGGGGCCGGCGGCGCGGCGAGCGCCATCGCCTTCGCGCTTGCGGCGGCGGGCGTGGCGCGCCTG
ACCATCCTTAACCGCACCGCCGACCGCGCCGAGGCGCTGGCGGCGCGCCTGCGCGCCGCCTACCCTAGCCTCGCGATCGC
CGCGGAGGGCACCCAGGCGGAGCACGACCTCCTCGTCAACGGCACGTCGCTCGGCATGCGCCCGCAGGACGCCGCCCCCT
TCGATCTGACCACGCTCCACGCCGGCCAGTTCGTCGCCGAGGCGATCATGGATCCGGAGACCACGCCGCTCCTCGCCGCG
GCGCTGGCGGCCGGCTGCCGCATTCAGAGGGGGCTACCGATGCTGGAGTGCCAGATCGCCCTCATGGCCCGCCACATGGG
CGCCCTCTGA

Upstream 100 bases:

>100_bases
CCGAGGCCAGCTTCGTAACCGGACAGACCGTCGATGTCGCCGGCGGCCTCTACATGACGTGAGCCGGAGCCGGTCAGGAC
AGATGGACGGGAGGACGGCC

Downstream 100 bases:

>100_bases
GGCTGGATCCGAGGACTGAGCATGGCGCGCACCGTGGGATCGACCGACATCGACGTCGTCGCGGCGGGCGTCTTCGACTA
CGTGATCGTGGGCGGCGGCA

Product: shikimate dehydrogenase substrate binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MNSALTAAGITGRTRVYGILADPIYHVKAPEVMGALFARHGVDGVLVPLHVTADGLAAVVDGLRHLRNFGGFIATVPHKT
ATTGLCDALTREAEQIGAVNCVRRDADGRMIGTMLDGIGFVEALRVSGLEPRGRNVALAGAGGAASAIAFALAAAGVARL
TILNRTADRAEALAARLRAAYPSLAIAAEGTQAEHDLLVNGTSLGMRPQDAAPFDLTTLHAGQFVAEAIMDPETTPLLAA
ALAAGCRIQRGLPMLECQIALMARHMGAL

Sequences:

>Translated_269_residues
MNSALTAAGITGRTRVYGILADPIYHVKAPEVMGALFARHGVDGVLVPLHVTADGLAAVVDGLRHLRNFGGFIATVPHKT
ATTGLCDALTREAEQIGAVNCVRRDADGRMIGTMLDGIGFVEALRVSGLEPRGRNVALAGAGGAASAIAFALAAAGVARL
TILNRTADRAEALAARLRAAYPSLAIAAEGTQAEHDLLVNGTSLGMRPQDAAPFDLTTLHAGQFVAEAIMDPETTPLLAA
ALAAGCRIQRGLPMLECQIALMARHMGAL
>Mature_269_residues
MNSALTAAGITGRTRVYGILADPIYHVKAPEVMGALFARHGVDGVLVPLHVTADGLAAVVDGLRHLRNFGGFIATVPHKT
ATTGLCDALTREAEQIGAVNCVRRDADGRMIGTMLDGIGFVEALRVSGLEPRGRNVALAGAGGAASAIAFALAAAGVARL
TILNRTADRAEALAARLRAAYPSLAIAAEGTQAEHDLLVNGTSLGMRPQDAAPFDLTTLHAGQFVAEAIMDPETTPLLAA
ALAAGCRIQRGLPMLECQIALMARHMGAL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=262, Percent_Identity=30.1526717557252, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1789675, Length=254, Percent_Identity=31.1023622047244, Blast_Score=85, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 27757; Mature: 27757

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSALTAAGITGRTRVYGILADPIYHVKAPEVMGALFARHGVDGVLVPLHVTADGLAAVV
CCCCCCCCCCCCCCEEEEEECCCEEECCCHHHHHHHHHHCCCCCEEEEEEECHHHHHHHH
DGLRHLRNFGGFIATVPHKTATTGLCDALTREAEQIGAVNCVRRDADGRMIGTMLDGIGF
HHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCHHHHHEECCCCCCHHHHHHHHHH
VEALRVSGLEPRGRNVALAGAGGAASAIAFALAAAGVARLTILNRTADRAEALAARLRAA
HHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
YPSLAIAAEGTQAEHDLLVNGTSLGMRPQDAAPFDLTTLHAGQFVAEAIMDPETTPLLAA
CCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHH
ALAAGCRIQRGLPMLECQIALMARHMGAL
HHHHCCHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNSALTAAGITGRTRVYGILADPIYHVKAPEVMGALFARHGVDGVLVPLHVTADGLAAVV
CCCCCCCCCCCCCCEEEEEECCCEEECCCHHHHHHHHHHCCCCCEEEEEEECHHHHHHHH
DGLRHLRNFGGFIATVPHKTATTGLCDALTREAEQIGAVNCVRRDADGRMIGTMLDGIGF
HHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCHHHHHEECCCCCCHHHHHHHHHH
VEALRVSGLEPRGRNVALAGAGGAASAIAFALAAAGVARLTILNRTADRAEALAARLRAA
HHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
YPSLAIAAEGTQAEHDLLVNGTSLGMRPQDAAPFDLTTLHAGQFVAEAIMDPETTPLLAA
CCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHH
ALAAGCRIQRGLPMLECQIALMARHMGAL
HHHHCCHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA