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The map label for this gene is sasA [H]

Identifier: 170746672

GI number: 170746672

Start: 236339

End: 237724

Strand: Reverse

Name: sasA [H]

Synonym: Mrad2831_0223

Alternate gene names: 170746672

Gene position: 237724-236339 (Counterclockwise)

Preceding gene: 170746673

Following gene: 170746669

Centisome position: 3.91

GC content: 68.61

Gene sequence:

>1386_bases
GTGCGCCTTCTTGAGATCCGGCGCACCAGCGGCTTCCGGGTCGCCTGCCTGTTCTTCGCGACCTTCGGGACCGCGTCGCT
CGCGCTGTCGGGCTTCCTGTACGTCGACACGCGCAGCTACGGCCGCAAGGCCGCGTTCGAGTGGGTCGGGTGGGAGTCGA
AGCACCTTCTGAGCCTGTCGCCGCGGGCGCTGCGCGAGCGCATCGACGCCTCCGAGGATTTCGCCGAAGGCGGCCGACCG
CTCGTCCTGTTCGGGCCAGACCACGTGCGCCGGGCGGGCGCGCCGATCGACTTTCCCGATCAGGCGCCGATCGGGAGGCC
GTTCATCCTGTCGCAGCCGGTGGACCACCGCAGCCGCACGCTGTTCAGCCAGCTCACCGAGCTCCCGAGCGGCGAATACG
TCCTGGTCAGCCGCTCGGCCCAGGATCTTCAGGCTCTCGAGAAGGCGCTGGTCGAGACCTTCGTCTGGGGGATGGCCGCC
ACCATCGTCATCGGCCTGATCGGTGCCGTGGTCTTCGGTGCCGGCTCACTGCGGCAGAACGATGCGATCACCAAGGCGGT
CGAGCGCATCATGCGCGGCGACCTGAGCGAGCGCCTGCCGACCCGCGGCGTCTCGGCCGACCTCGCCCACCTGACCCGCG
TCGTCAACGACATGCTGGATCAGCTCGAGCGGCTGATGCTGGAGATCAAGGGCGTTAACGAGAACATCGCCCACGACCTG
CGCACGCCGCTGACCCGGGTGGTCGGCACGCTGGAGCGCTCGCTCCGCAAGGCCGACAGCGTGGAGGCCTTTCGCACCTT
CAACGAGGACGTCCTCGCCGAGGTCAAGACCATCGTCGTCCGGTTCTCGGCCCTCTTGCGCATCTCCGAAATGGAAGACC
GTCTGCGCCGGTCGGGCTTCACGCAGGTCGATCTCGGTCGGCTGCTCGAGGACGCGGTGGAGTATTACGAACCCCTCGCC
AGCGAGCGCGGCATCGAACTCCTCTGGGACCGCCCGGAAGACACCTGTGCGATCGAGGGCGACCGCAGCCTGATCTTCGA
GGCGGTGAGCAACCTGATCGACAATGCCCTGAAGTTCACGCCGGCCGGAGGAGAGGTGACGGTCGCGCTGATCCGGAACC
CGCTGGGAATCCAGGTCACGGACACGGGCTGCGGCATCCCGCCCGAGGAGCTGAGTGCCGTTCGCGCCCGGTACCGCCGC
GGGGCGCTGAAGACCGACAAGAGCGGCTTCGGGATCGGCCTGAGCCTGGTCGACTCCATCGCGCGGCTGCACAGCGCCGC
CTTCGACATCGCCTCCGACGGGACCGGCTGCCGCGTGACCCTCAGCTGGACCCACACGGTCGGGACTGATCCGTCCGTCG
ATCTCCTGCCCGCCGCGTCCCACTGA

Upstream 100 bases:

>100_bases
AGCGTCATCGACGTCCATATCGGCAAGATCCGTAAGAAGTTGGATCCCGACGGGCTGAACCCGCGGATCCACACGGTGCG
CAACACCGGCTTCATTCTCC

Downstream 100 bases:

>100_bases
CGCCGTCGCGCCCGGCCGATCCCGTCCCGCGGGATCGGCCGGGCGCATGGCCTCGGAGGGGTCTCAGTAGGACGGCTGAC
CGCGCCGACGCTCGCGGCTG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MRLLEIRRTSGFRVACLFFATFGTASLALSGFLYVDTRSYGRKAAFEWVGWESKHLLSLSPRALRERIDASEDFAEGGRP
LVLFGPDHVRRAGAPIDFPDQAPIGRPFILSQPVDHRSRTLFSQLTELPSGEYVLVSRSAQDLQALEKALVETFVWGMAA
TIVIGLIGAVVFGAGSLRQNDAITKAVERIMRGDLSERLPTRGVSADLAHLTRVVNDMLDQLERLMLEIKGVNENIAHDL
RTPLTRVVGTLERSLRKADSVEAFRTFNEDVLAEVKTIVVRFSALLRISEMEDRLRRSGFTQVDLGRLLEDAVEYYEPLA
SERGIELLWDRPEDTCAIEGDRSLIFEAVSNLIDNALKFTPAGGEVTVALIRNPLGIQVTDTGCGIPPEELSAVRARYRR
GALKTDKSGFGIGLSLVDSIARLHSAAFDIASDGTGCRVTLSWTHTVGTDPSVDLLPAASH

Sequences:

>Translated_461_residues
MRLLEIRRTSGFRVACLFFATFGTASLALSGFLYVDTRSYGRKAAFEWVGWESKHLLSLSPRALRERIDASEDFAEGGRP
LVLFGPDHVRRAGAPIDFPDQAPIGRPFILSQPVDHRSRTLFSQLTELPSGEYVLVSRSAQDLQALEKALVETFVWGMAA
TIVIGLIGAVVFGAGSLRQNDAITKAVERIMRGDLSERLPTRGVSADLAHLTRVVNDMLDQLERLMLEIKGVNENIAHDL
RTPLTRVVGTLERSLRKADSVEAFRTFNEDVLAEVKTIVVRFSALLRISEMEDRLRRSGFTQVDLGRLLEDAVEYYEPLA
SERGIELLWDRPEDTCAIEGDRSLIFEAVSNLIDNALKFTPAGGEVTVALIRNPLGIQVTDTGCGIPPEELSAVRARYRR
GALKTDKSGFGIGLSLVDSIARLHSAAFDIASDGTGCRVTLSWTHTVGTDPSVDLLPAASH
>Mature_461_residues
MRLLEIRRTSGFRVACLFFATFGTASLALSGFLYVDTRSYGRKAAFEWVGWESKHLLSLSPRALRERIDASEDFAEGGRP
LVLFGPDHVRRAGAPIDFPDQAPIGRPFILSQPVDHRSRTLFSQLTELPSGEYVLVSRSAQDLQALEKALVETFVWGMAA
TIVIGLIGAVVFGAGSLRQNDAITKAVERIMRGDLSERLPTRGVSADLAHLTRVVNDMLDQLERLMLEIKGVNENIAHDL
RTPLTRVVGTLERSLRKADSVEAFRTFNEDVLAEVKTIVVRFSALLRISEMEDRLRRSGFTQVDLGRLLEDAVEYYEPLA
SERGIELLWDRPEDTCAIEGDRSLIFEAVSNLIDNALKFTPAGGEVTVALIRNPLGIQVTDTGCGIPPEELSAVRARYRR
GALKTDKSGFGIGLSLVDSIARLHSAAFDIASDGTGCRVTLSWTHTVGTDPSVDLLPAASH

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=285, Percent_Identity=26.3157894736842, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1790861, Length=279, Percent_Identity=28.3154121863799, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788279, Length=302, Percent_Identity=23.1788079470199, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786600, Length=216, Percent_Identity=28.7037037037037, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788393, Length=249, Percent_Identity=25.7028112449799, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788549, Length=210, Percent_Identity=27.1428571428571, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789403, Length=322, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790346, Length=245, Percent_Identity=24.4897959183673, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 50673; Mature: 50673

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLEIRRTSGFRVACLFFATFGTASLALSGFLYVDTRSYGRKAAFEWVGWESKHLLSLS
CCCEEEECCCCCEEHHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHCCCCCCCCEECCC
PRALRERIDASEDFAEGGRPLVLFGPDHVRRAGAPIDFPDQAPIGRPFILSQPVDHRSRT
HHHHHHHCCCCHHHHCCCCEEEEECCHHHHHCCCCCCCCCCCCCCCCEEECCCCCHHHHH
LFSQLTELPSGEYVLVSRSAQDLQALEKALVETFVWGMAATIVIGLIGAVVFGAGSLRQN
HHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DAITKAVERIMRGDLSERLPTRGVSADLAHLTRVVNDMLDQLERLMLEIKGVNENIAHDL
HHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
RTPLTRVVGTLERSLRKADSVEAFRTFNEDVLAEVKTIVVRFSALLRISEMEDRLRRSGF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TQVDLGRLLEDAVEYYEPLASERGIELLWDRPEDTCAIEGDRSLIFEAVSNLIDNALKFT
CHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHEEC
PAGGEVTVALIRNPLGIQVTDTGCGIPPEELSAVRARYRRGALKTDKSGFGIGLSLVDSI
CCCCCEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
ARLHSAAFDIASDGTGCRVTLSWTHTVGTDPSVDLLPAASH
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MRLLEIRRTSGFRVACLFFATFGTASLALSGFLYVDTRSYGRKAAFEWVGWESKHLLSLS
CCCEEEECCCCCEEHHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHCCCCCCCCEECCC
PRALRERIDASEDFAEGGRPLVLFGPDHVRRAGAPIDFPDQAPIGRPFILSQPVDHRSRT
HHHHHHHCCCCHHHHCCCCEEEEECCHHHHHCCCCCCCCCCCCCCCCEEECCCCCHHHHH
LFSQLTELPSGEYVLVSRSAQDLQALEKALVETFVWGMAATIVIGLIGAVVFGAGSLRQN
HHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DAITKAVERIMRGDLSERLPTRGVSADLAHLTRVVNDMLDQLERLMLEIKGVNENIAHDL
HHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
RTPLTRVVGTLERSLRKADSVEAFRTFNEDVLAEVKTIVVRFSALLRISEMEDRLRRSGF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TQVDLGRLLEDAVEYYEPLASERGIELLWDRPEDTCAIEGDRSLIFEAVSNLIDNALKFT
CHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHEEC
PAGGEVTVALIRNPLGIQVTDTGCGIPPEELSAVRARYRRGALKTDKSGFGIGLSLVDSI
CCCCCEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
ARLHSAAFDIASDGTGCRVTLSWTHTVGTDPSVDLLPAASH
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA